Extreme-phenotype genome-wide association study (XP-GWAS) of powdery mildew race 2 W tolerance in the USDA Citrullus germplasm collection by Sandra E. Branham, Venkata Rao Ganaparthi, W. Patrick Wechter, Younghoon Park, Todd Wehner, Angela Davis, Antonia Tetteh, Laura Massey, Sue Hammar, Rebecca Grumet, Shaker Kousik, Amnon Levi

“…Two adjacent SNPs on chromosome 7 were significantly associated with P. xanthii race 2 W tolerance in the bulks and two additional SNPs had a strong signal in the XP-GWAS analysis. Kompetitive Allele-Specific PCR (KASP) markers were designed for sixteen SNPs across the three genomic regions. …”
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A cross-sectional study of the current status of psychological health and its correlation with academic performance in medical students: taking medical students in a medical univer... by Han Chunhong, Han Chunhong, Ding Jingjing, He Huan, Zheng Peiyao, Zhang Xiaona, Yang Xiaowen, Zheng Aiming

“…Analysis of the first and second-year academic performances of 2022 undergraduates revealed that assessment scores of PHQ-9, PSS, ISI, and BSSI had a correlation with the total GPA. However, no correlation was found between the GAD-7 values and the GPA. …”
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Plant-microbe interactions influence plant performance via boosting beneficial root-endophytic bacteria by Sai Guo, Rubin Pan, Yan Zhang, Quanwei Gu, Qirong Shen, Jian Yang, Luqi Huang, Zongzhuan Shen, Rong Li

“…We found that medicinal plants with different growth status had distinct root-endophytic bacterial communities. …”
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Association between magnesium depletion score and prostate cancer by Hongyang Gong, Xiaomei Lin, Shaoqun Huang

“…A total of 16,043 participants were included in this study, of whom 511 had PCa. After adjusting for all variables using multivariable logistic regression, each 1-unit increase in MDS was associated with a 26% higher prevalence of PCa (OR = 1.26, 95% CI: 1.05, 1.50). …”
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Caution when using network partners for target identification in drug discovery by Dandan Tan, Yiheng Chen, Yann Ilboudo, Kevin Y.H. Liang, Guillaume Butler-Laporte, J. Brent Richards

“…Two recent papers from Open Targets claimed that around half of US Food and Drug Administration-approved drugs had targets with direct human genetic evidence. …”
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Cardiovascular disease risk prediction by Framingham risk score in women with polycystic ovary syndrome by Mina Amiri, Maryam Mousavi, Mahsa Noroozzadeh, Fereidoun Azizi, Fahimeh Ramezani Tehrani

“…Results The Cox proportional hazards (HRs) model revealed that the CVD risk increased by 38% for each one-unit increase in the FRS [HR: 1.38 (95% CI: 1.14, 1.66)] in PCOS patients. The FRS had a C-statistic of 0.765, which indicated a satisfactory fit for CVD prediction in this population. …”
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Vagal nerve stimulation dynamically alters anxiety-like behavior in rats by A.G. Butler, J.K. Bassi, A.A. Connelly, M.R. Melo, A.M. Allen, S.J. McDougall

“…In contrast, higher-intensity VNS had no effect on c-Fos expression in noradrenergic neurons of either the nucleus of the solitary tract or locus coeruleus. …”
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The Impact of Coronavirus Disease-19 on Pregnancy Outcomes, A Case Series by Bilge Cetinkaya Demir, Ozge Albayrak, Kiper Aslan

“…Five of the patients treated in the intensive care unit died due to respiratory failure. Two patients had a miscarriage before the 20th week. There were four stillbirths. …”
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Relationship between METS-IR and ABSI index and the prevalence of nocturia: a cross-sectional analysis from the 2005–2020 NHANES data by Fei Xue, Yating Zhou

“…Specifically, compared to the lowest quartile (Q1), participants in the highest quartile (Q4) had an OR of 1.45 (95% CI: 1.30–1.61, p < 0.0001) for METS-IR and 1.38 (95% CI: 1.23–1.55, p < 0.0001) for ABSI. …”
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Attributes of cognitive impairment in patients on maintenance hemodialysis – A cohort study by Geet Gaurav, Deepa Sanjeev Sajjanar, G. V. Naregal, Sanjeev L. Sajjanar

“…About 88.6% of participants (n = 62) showed considerable cognitive impairment and 1.4% had frank dementia. A positive association was noted between cognitive impairment and the conditions of diabetes mellitus and hypertension with a relative risk of 1.02 and 1.11, respectively. …”
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A randomised trial comparing the clinical effectiveness of different emergency department healthcare professionals in soft tissue injury management by Jonathan Richard Benger, Jane Powell, Fiona Cramp, Carey Middleton McClellan

“…Patients were excluded if they had any of the following: injury greater than 72 hours old; systemic disease; dislocated joints; recent surgery; unable to give informed consent (eg, dementia), open wounds; major deformities; opiate analgesia required; concurrent chest/rib injury; neurovascular deficits and associated fracture.Interventions Patients were randomised to treatment by ESPs, ENPs or routine care provided by doctors (of all grades).Main outcome measures Upper-limb and lower-limb functional scores, quality of life, physical well-being, preference-based health measures and the number of days off work.Results The clinical outcomes of soft tissue injury treated by ESPs and ENPs in the ED were equivalent to routine care provided by doctors.Conclusions As all groups were clinically equivalent it is other factors such as cost, workforce sustainability, service provision and skill mix that become important. …”
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Exploring DNA methylation, telomere length, mitochondrial DNA, and immune function in patients with Long-COVID by Andrea Polli, Lode Godderis, Dries S. Martens, Madhura Shekhar Patil, Jolien Hendrix, Arne Wyns, Jente Van Campenhout, Emma Richter, Lara Fanning, Olivia Vandekerckhove, Eveline Claeys, Wim Janssens, Natalie Lorent

“…Results Of the 358 participants, 328 were hospitalised, of which 130 had severe symptoms requiring intensive care admission; 30 patients were ambulatory referrals. …”
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Efficacy and fibrinogen correlations of defibrinogen therapy in idiopathic sudden sensorineural hearing loss by Bing Wang, Wen Zhang, Jin Zhang, Qimei Yang, Bing Han, Hui Liu, Ziyu Zhao

“…Spearman’s rank correlation analysis indicated weak negative correlations between fibrinogen levels on day 1 and day 3 and hearing improvement, while the level on day 5±1 had a moderate negative correlation. Throughout the follow-up period, no major complications were observed. …”
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Improved early postoperative cognition in elderly gastrointestinal patients: a randomized controlled trial on the role of ultrasound-guided stellate ganglion block by Ruyue Xue, Yuexian Li, Mei Zhan, Lin Yang, Defeng Sun

“…Blood samples were analyzed for interleukin-6 (IL-6), superoxide dismutase (SOD), and malondialdehyde (MDA).ResultsThe SGB group had a significantly lower incidence of POCD on postoperative day one (p &lt; 0.05). …”
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Differences in Sexual Function Between Trimesters During Pregnancy: An Observational Study by Sunullah Soysal, Abdullah Sarioz, Umran Kilincdemir Turgut, Gokce Anik Ilhan, Yusuf Arman, Begum Yildizhan, Tanju Pekin

“…Index of female sexual function had a total and six sub-domain scores which assess the quality and frequency of sexual intercourse, desire, overall satisfaction, ability to achieve orgasm, and degree of clitoral sensation (c.sensation). …”
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Chemical Characteristics and Trends of Indian Summer Monsoon Rainfall: A Review by Aditi Majumdar, Dhrubajyoti Samanta, Reshmi Das

“…The majority of the ions in rainwater were highest in the Northwest while lowest in the Peninsular region. Cl– had a significant correlation with Na+ and NH4+ in the Hilly region, and with Na+ and Mg2+ in the West Central region suggesting it is sourced from both marine and anthropogenic sources. …”
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U-shaped association between TC/HDL-C ratio and osteoporosis risk in older adults by Chuanwei Zhao, Xiaochun Zhang, Xu Zhang, Bo Zhao, Yane Yang, Mu Lin, Wenli Qiao, Zeyao Hu, Haijie Yang

“…Among the participants, 1,608 had osteoporosis. A higher TC/HDL-C ratio was inversely associated with osteoporosis (OR: 0.92, 95% CI: 0.86–0.99, p = 0.02). …”
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Differences in fatty infiltration in thigh muscles and physical function between people with and without knee osteoarthritis and similar body mass index: a cross-sectional study by Jessica B. Aily, Marcos de Noronha, Ricardo J. Ferrari, Stela M. Mattiello

“…Results Forty-six participants were analyzed (23 in each group). The affected group had significantly higher intraMAT compared to the unaffected group (p < 0.05), but no differences were observed for interMAT. …”
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Examining tolerability, safety, and blinding in 1032 transcranial electrical stimulation sessions for children and adolescents with neuropsychiatric and neurodevelopmental disorder... by Andrea Battisti, Giulia Lazzaro, Luciana Ursumando, Barbara D’Aiello, Valeria Zanna, Floriana Costanzo, Stefano Vicari, Deny Menghini

“…Itching was the most common symptom, and active sessions were found to be more likely to induce AEs compared to sham sessions. Notably, tRNS had a higher AE likelihood than tDCS, possibly due to experimental differences. …”
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Peripheral neuropathy in the phase 3 ASPEN study of Bruton tyrosine kinase inhibitors for Waldenström macroglobulinemia by Benjamin M. Heyman, Stephen S. Opat, Björn E. Wahlin, Meletios-Athanasios C. Dimopoulos, Jorge J. Castillo, Alessandra Tedeschi, Constantine S. Tam, Christian Buske, Roger G. Owen, Véronique Leblond, Judith Trotman, Gisoo Barnes, Wai Y. Chan, Jingjing Schneider, Heather Allewelt, Aileen Cohen, Jeffrey V. Matous

“…Patients with PN symptom resolution had greater improvement in HRQOL. Physical functioning improved in patients with PN symptom resolution and was unchanged in patients without resolution. …”
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