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The use of polyphenols extracted from Chinese sweet leaf tea (Rubus suavissimus S. Lee.) as novel drugs for the treatment of metabolic dysfunction associated steatotic liver diseas...
Published 2025-07-01“…Gene expression analysis revealed modulation of key metabolic regulators, including SREBP1, ACACA, AMPK, and PPARα. …”
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Analysis of ferritinophagy-related genes associated with the prognosis and regulatory mechanisms in non-small cell lung cancer
Published 2025-03-01“…Lung cancer remains a major global health issue, with non-small cell lung cancer (NSCLC) constituting approximately 85% of cases. …”
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Astrocytic NLRP3 cKO mitigates depression-like behaviors induced by mild TBI in mice.
Published 2025-02-01“…Background: Reports indicate that depression is a common mental health issue following traumatic brain injury (TBI). Our prior research suggests that Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)-related neuroinflammation, modulated by glial cells such as astrocytes, is likely to play a crucial role in the progression of anxiety and cognitive dysfunction. …”
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Transgenerational effects of the genocide against the Tutsi in Rwanda: A post-traumatic stress disorder symptom domain analysis [version 2; peer review: 2 approved, 1 approved with...
Published 2020-01-01“…As a secondary analysis, we explored the relationship between DNA methylation in the glucocorticoid receptor (NR3C1) locus, an important stress modulating gene, and PTSD symptom domains, finding an association between DNA methylation and re-experiencing among genocide-exposed mothers that exceeded any other observed associations by approximately two-fold. …”
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Smart Waste Management Framework for Green Cities: Integrating IoT, LoRa, and Deep Learning for Efficient Waste Classification and Management
Published 2025-08-01“… Waste management is recognized as a crucial issue in modern civilization, requiring substantial effort and resources while significantly impacting various societal aspects. …”
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Low storage temperature maintains the quality, antioxidant activity, and nutraceutical properties of edible flowers and their anti-inflammatory effects on RAW 264.7 cells
Published 2025-06-01“…Moreover, the inflammatory and anti-inflammatory effects of MeOH extracts (0–5 mg/mL, at the zero time) were also explored in RAW 264.7 cells. Almost all flowers modulated inflammation; A. goyazensis effectively inhibited NO generation and is therefore a candidate functional food.…”
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Polymeric Nanomedicines in Diabetic Wound Healing: Applications and Future Perspectives
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Adipose Factor ANGPTL4: Its Role in Aging Mechanisms and Associated Diseases
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Highlight of Grid-connected PV systems in administrative buildings in Egypt
Published 2017-03-01“…The two components that determine the total initial price of a grid- connected PV system are the modules and the balance of systems (BOS). The BOS includes different components such as mounting frames, inverters and site- specific installation hardware.…”
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Interference in melanoma CD248 function reduces vascular mimicry and metastasis
Published 2022-11-01“…Abstract Background Tumor vascular mimicry is an emerging issue that affects patient survival while having no treatment at the current moment. …”
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Icariin-Enhanced Osteoclast-Derived Exosomes Promote Repair of Infected Bone Defects by Regulating Osteoclast and Osteoblast Communication
Published 2024-11-01“…Additionally, ICA-OC-Exo was administered into the localized bone defect of the infected bone rat models, and bone formation was assessed using Micro-CT.Results: Icariin increased the presence of MVBs in the cytoplasm through modulation of the MITF/Rab27A signaling pathway, resulting in higher number of ICA-OC-Exo compared to OC-Exo. …”
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The relationship between anti-merozoite antibodies and incidence of Plasmodium falciparum malaria: A systematic review and meta-analysis.
Published 2010-01-01“…Heterogeneity, in terms of clinical and methodological diversity between studies, was an important issue in the meta-analysis of IgG responses to merozoite antigens.…”
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