Probiotic treatment in an intensive care unit: a narrative review by Sato Takeaki

“…Probiotics, defined as live beneficial microorganisms, can counteract dysbiosis by modulating immune responses, restoring microbial balance, and reducing intestinal inflammation. …”
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Vitamin D, Calcium, Parathyroid Hormone, and Sex Steroids in Bone Health and Effects of Aging by Hitesh Kumar Bhattarai, Shreya Shrestha, Kabita Rokka, Rosy Shakya

“…Bone health is a complex issue affected by multiple hormones and minerals. …”
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Artificial Intelligence in Medical Education: Promise, Pitfalls, and Practical Pathways by Saroha S

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DEVELOPING YOUTH RESILIENCE IN CONDITIONS OF SOCIAL INSTABILITY AND WAR by Vira Syniakova, Yuliia Bokhonkova, Mykyta Minin

“…In the context of ongoing social instability and armed conflict in Ukraine, the issue of youth resilience has become increasingly relevant. …”
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Effect of a 6-Month Functional Food Intervention on the Microbiota of Stunted Children in East Nusa Tenggara, Indonesia—A Randomized Placebo-Controlled Parallel Trial by Ingrid S. Surono, Koen Venema, Subijanto Martosudarmo, Pratiwi D. Kusumo

“…In conclusion, although there was no difference between the interventions, understanding the dynamics and the role of the gut microbiota in this process might allow healthcare providers to develop targeted nutritional strategies aimed at optimizing health outcomes for children at risk of stunting, thereby addressing a critical global health issue.…”
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Immunotherapy and vaccine-based approaches for atherosclerosis prevention: a systematic review study by Mansoureh Shekarchizadeh Esfahani, Mansour Siavash, Raheleh Sadat Sajad, Amirhossein Ramezani Ahmadi, Mozhgan Karimifar, Mojtaba Akbari, Masood Shekarchizadeh

“…Abstract Introduction Cardiovascular disease is a major global health issue, and atherosclerosis is a leading cause of cardiovascular conditions. …”
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Pharmacological underlying mechanisms of the anticancer effect of licorice: Bioinformatics and experimental verification by Mengqi Liu, Lingping Fu, Hao Fu, Yu Chen, Mengxia Wu, Hanchun Liu

“…Purpose: Cancer is the second leading cause of human mortality and has rapidly become a major global issue. According to traditional Chinese medicine (TCM) theory, the primary pathogenesis of cancer is the deficiency of ''vital Qi''. …”
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Embedded machine learning for fault detection in conveyor systems using multi-sensor data and discrete wavelet transform by Hoang Duc Do, Quang Minh Vien, Khang Hoang Vinh Nguyen, Can Duy Le

“…The microcontroller is equipped with a 6-axis Inertial Measurement Unit (IMU) and a Pulse Density Modulation (PDM) microphone, enabling it to monitor vibrations and sounds generated during conveyor belt operation. …”
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The effects of 5-HT on vascular endothelial dysfunction in patients with panic disorder by Yueqi Feng, Xixi Li, Zijia Li, Xinyi He, Yanqing Tang, Wen Tian

“…However, the influence of SSRIs on CVD outcomes remains a controversial issue with conflicting findings from various studies. …”
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Exploring mental health challenges and violence risks in high school population by Saleha Khan, Samratul Fuadah, Nadeem Ikram, Elias Aljouny, Mohammed Talha Mohammed Zubair, Sumera Nisar

“…Concerns for adolescence mental health is an emerging global issue. Second to home, students spend a lot of time in school and amongst peers thus it is important to maintain a school environment conducive to optimal mental and physical health. …”
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3-D UXSE-Net for Seismic Channel Detection Based on Satellite Image Enhanced Synthetic Datasets by Xinke Zhang, Yihuai Lou, Naihao Liu, Daosheng Ling, Yunmin Chen

“…However, insufficient labeled training data remains a key challenge for refining DL models. To address this issue, we propose a workflow that automatically generates synthetic datasets by integrating channel features extracted from high-resolution satellite images. …”
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TAK-653 Reverses Core Depressive Symptoms in Chronic Stress-Induced Monkey Model by Ling Li, Zhiting Zhang, Xinhe Liu, Mengni Zhou, Shenglin Wen, Ji Dai

“…<b>Background:</b> Major Depressive Disorder represents a prevalent and critical mental health issue that highlights the pressing need for innovative therapeutic solutions. …”
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Fine‐Tuning 2D Heterogeneous Channels for Charge‐Lock Enhanced Lithium Separation from Brine by Yaxin Hao, Xin Liu, Yaoling Zhang, Xin Zhang, Zhan Li, Ximeng Chen

“…This approach integrates porous ZnFe2O4/ZnO nanosheets into Ag+‐modulated sub‐nanometer interlayer channels, forming channels optimized for Li⁺ extraction. …”
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Protective effects of Nippostrongylus brasiliensis-derived uridine via the apical sodium-dependent bile acid transporter in a mouse model of TNBS-induced inflammatory bowel disease by Caiyi Yuan, Qiang Wang, Yuying Chen, Yuying Chen, Xin Ding, Qiang Zhang, Jiakai Yao, Bei Zhang, Yang Dai, Yang Dai, Hongxia Bai

“…The exploration of novel intervention strategies remains a key scientific issue that is urgently needed for IBD treatment. …”
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Cenobamate reduces epileptiform activity in the ex vivo F98 rat glioma model by Ferdinand Forberger, Fabiana Santana Kragelund, Katrin Porath, Rüdiger Köhling, Rüdiger Köhling, Timo Kirschstein, Timo Kirschstein, Falko Lange, Falko Lange

“…There is a need for new anticonvulsants to address this issue. Therefore, for the first time, we evaluated the efficacy of cenobamate, a novel anticonvulsant shown to inhibit persistent sodium currents and modulate GABAA receptor function, in a preclinical model of glioma-associated epilepsy. …”
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A Combination of Flavonoids Suppresses Cell Proliferation and the E6 Oncogenic Pathway in Human Papillomavirus-Transformed Cells by Federico De Marco, Fabio Altieri, Stefano Giuliani, Italia Falcone, Susanna Falcucci, Mariassunta Tedesco, Roberto Becelli

“…To shed light on such a controversial issue, a restricted list of promising polyphenols were evaluated for their antineoplastic activity on HPV-transformed cells. …”
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RNF138 contributes to cisplatin resistance in nasopharyngeal carcinoma cells by Hangyu Xu, Qing Yin, Linna Fan, Yating Zhao, Biying Song, Qifan Xu, Jie Zhu, Meifen Xu

“…These findings indicate that the modulation of RNF138 could potentially address the issue of chemotherapy failure by overcoming cisplatin resistance in NPC cells, making it a promising candidate for targeted drug therapy.…”
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Effect of <i>Hottentotta judaicus</i> Scorpion Venom on Nociceptive Response and Inflammatory Cytokines in Mice Using Experimental Hyperalgesia by Lara Haddad, Amira Chender, Rabih Roufayel, Claudine Accary, Adolfo Borges, Jean Marc Sabatier, Ziad Fajloun, Marc Karam

“…Scorpion envenomation is a public health issue in tropical and subtropical regions. Currently, there is limited data on the biological effects of <i>Hottentotta judaicus</i> scorpion venom (HjSV) in mammals. …”
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Omega-3 Fatty Acids and Exercise in Obesity Management: Independent and Synergistic Benefits in Metabolism and Knowledge Gaps by Viviana Sandoval, Álvaro Vergara-Nieto, Amanda Bentes, Saulo Silva, Carolina Núñez, Sergio Martínez-Huenchullán

“…Obesity is a significant global health issue, profoundly affecting metabolic and cardiovascular health and other related chronic conditions. …”
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Metabolically Engineered Extracellular Vesicles Released From a Composite Hydrogel Delivery System Regulate the Microenvironment for Periprosthetic Osteolysis Treatment by Chenchen Wang, Jiang Ju, Chao Fu, Bingbo Bao, Tianhui Ren, Yanan Li, Yuan Wang, Sheng Han, Yuan Wang, Xuan Huang, Hongxing Hu, Xianyou Zheng

“…Collectively, our findings establish DS‐EVs as a transformative therapeutic modality for periprosthetic osteolysis through dual modulation of the osseointegration microenvironment and macrophage phenotypic heterogeneity.…”
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