Therapeutic Effects of Fire Needling Acupuncture on Pain Relief and Cartilage Protection in MIA-Induced Knee Osteoarthritis Rats: The Role of Macrophage Polarization in Synovium an... by Wei J, Yang X, Ge X, Zhao L, Liu X, Zhang J, Zhou J, Zhang C, Li W, Li Z, Lyu T, Wang Y, Yuan F, Liu L, Li B

Get full text

Mast Cells Promote Inflammatory Th17 Cells and Impair Treg Cells Through an IL-1β and PGE2 Axis by Leveque E, Joulia R, Battut L, Laurent C, Valitutti S, Cénac N, Dietrich G, Espinosa E

Get full text

Dynamical Characteristics of Isolated Donors, Acceptors, and Complex Defect Centers in Novel ZnO by Devki N. Talwar, Piotr Becla

“…Despite earlier evidence of attaining p-type wz ZnO with N doping, the problem persists in achieving reproducible p-type conductivity. This issue is linked to charging compensation by intrinsic donors and/or background impurities. …”
Get full text

Delivery of miR-26a-5p by Subcutaneous Adipose Tissue-Derived Extracellular Vesicles Alleviates Acute Lung Injury in Mice Through CHUK/NF-κB Pathway by Xie Y, Ran L, Yue C, Wang C, Chen F, Su Y, Qin Y, Zhang Q, Liu J, Du N, Zhang L, Jiang Y, Liu G

Get full text

DS-Modified Paeoniflorin pH-Responsive Lipid–Polymer Hybrid Nanoparticles for Targeted Macrophage Polarization in a Rat Model of Rheumatoid Arthritis by Zhang J, Yang J, Yu Z, Bai H, Wang Y, Wang R

Get full text

Immune Microenvironment Characterization and Machine Learning-Guided Identification of Diagnostic Biomarkers for Ulcerative Colitis by Zheng Q, Wang L, Zhang Y, Peng J, Hou J, Wang H, Ma Y, Tang P, Li Y, Li H, Chen Y, Li J, Chen Y

Get full text

Multi-omics insights into functional alterations of the liver in growth-retarded offspring: transcriptomic, epigenetic and metabolomic profiles by Qun Lan, Sui Liufu, Xin Xu, Bohe Chen, Wenwu Chen, Kaiming Wang, Caihong Liu, Lanlin Xiao, Xiaolin Liu, Lei Yi, Jingwen Liu, Qiuchun Deng, Haiming Ma, Meng Kang

“…Abstract Background Growth retardation is a globally prevalent clinical issue, particularly in preterm offspring. It frequently occurs during the early postnatal development of piglets and results in high mortality. …”
Get full text

HMGB1 Inhibition Alleviates Chronic Nonbacterial Prostatitis by Suppressing M1 Polarization of Macrophages by Zhou J, Ding L, Chen J, Chen C, Jiang P, Mei Z, Jiang Q, Hua X

Get full text

Diseño de un Software de Intermediación de Comunicación para Sistemas Distribuidos de Tiempo Real Críticos en Java by Daniel Tejera, Alejandro Alonso, Miguel A. de Miguel

“…It provides independence from network protocol defining a network interface and modules. The JRMP protocol was modified to include two phases, non-functional parameters, and message size optimizations. …”
Get full text

N4BP3 Activates TLR4-NF-κB Pathway in Inflammatory Bowel Disease by Promoting K48-Linked IκBα Ubiquitination by Jiang W, Yin J, Han M, He W, Zhao Y, Hu J, Wang M, Wang S, Xu J, Deng C, Li J, Gong X, Shen Y

Get full text

Integration of co-culture conditions and 3D gelatin methacryloyl hydrogels to improve human-induced pluripotent stem cells-derived cardiomyocytes maturation by Ilaria Gisone, Monica Boffito, Elisa Persiani, Roberta Pappalardo, Elisa Ceccherini, Andrea Alliaud, Manuela Cabiati, Rossella Laurano, Letizia Guiducci, Chiara Caselli, Rosetta Ragusa, Claudio Cassino, Chiara Ippolito, Silvia Del Ry, Susanna Sartori, Antonella Cecchettini, Antonella Cecchettini, Salvador Fernández-Arroyo, Gianluca Ciardelli, Federico Vozzi

“…Approaches proposed to overcome this issue are based on better reproducing the in vivo native CMs microenvironment. …”
Get full text

Inhibition of Ferroptosis by Adipose Stem Cell-Derived Apoptotic Vesicles Enhances Angiogenesis and Accelerates Diabetic Wound Healing by Zhang J, Kuang J, Gong S, Wang H, Ding F, Zhao L, Shi L, Liu S, Zhao Y, Liu J, Dou G

Get full text

Addressing Disparities in access to expert physical therapy care and diagnosis for lumbar radiculopathy by Manum Tahir, Hammad Haider

“…It is our privilege to bring attention to this significant issue of Lumbar radiculopathy, its high economic burden in accessing medical diagnosis, expert physical therapy care and advanced electrotherapy modalities. …”
Get full text

Effect of the Foliar Application of Copper Nanoparticles on the Growth and Yield of Persian Leek (Allium ampeloprasum subsp. Persicum) under Salinity Stress by F. Shakarami, S. Mousavi-Fard, A. Rezaei Nejad, F. Beiranvand

“…Over recent decades, the escalating demand for irrigation in arid and semi-arid regions has intensified this issue, making it a major agricultural challenge. …”
Get full text

Level-8 Ph.D. Programs In Medical Sciences: High Time For The Higher Education Commission (HEC) Of Pakistan To Establish A Medical Wing by Wafa Omer

“…However, developing a proper competency framework with the inclusion of clinical modules uniformly across all these fields can improve the quality and ensure standardisation across all disciplines in Medical and Diagnostic Sciences. …”
Get full text

Analyse de pratiques interdisciplinaires dans l’enseignement supérieur by Valérie Camel, Agnès Fargue-Lelièvre

“…This study is a report covering several years on three teaching modules with different degrees of interdisciplinarity for engineering students. …”
Get full text

Systematic Review: How to reduce the car cabin temperature using solar energy? by Noor Al-Huda A.Taher, Ali A . F . Al- Hamadani

“… The two biggest issues we have are the energy crisis and global warming. …”
Get full text

WSN intrusion detection method using improved spatiotemporal ResNet and GAN by Yang Jing

“…Then, an improved spatiotemporal residual network model is designed, in which the spatial and temporal features of the data are extracted and fused through multi-scale one-dimensional convolution modules and gated loop unit modules, and identity maps are added based on the idea of residual networks to avoid network degradation and other issues. …”
Get full text

Renal denervation: a new life of the technology by T. Y. Chichkova, S. E. Mamchur, M. P. Romanova, E. A. Khomenko

Get full text

Messaging malignancy: Tumour-derived exosomes at the nexus of immune escape, vascular remodelling and metastatic competence by Yildirim Duygu T., Baki Yildirim A., Salzet Michel, Bertelli Matteo, Beccari Tommaso, Prakash Satya, Pascucci Luisa, Dundar Munis

“…Recent high-throughput technologies have enabled detailed profiling of exosomal cargo; however, substantial challenges persist in their clinical application due to issues in isolation and standardization. This review systematically dissects these molecular biogenesis controversies, the roles of tumor-derived exosomes in modulating angiogenesis, immune escape, metastasis, and therapy resistance, and critically evaluates barriers hindering their clinical adoption.…”
Get full text