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α‐ZnO Manipulated Growth of Ag Gird on AgNWs Enables High Conductive Flexible Electrode for Large‐Area Monolithic Organic Photovoltaics
Published 2025-03-01“…However, the complex 3D multi‐component structure of AgNWs electrodes will exacerbate the aggregation of large Ag particles, causing the device short circuits. To address this issue, the relationship between the surface energy of modification layers and the morphology and conductivity of ultrathin Ag on AgNWs is studied. …”
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SIRT7 remodels the cytoskeleton via RAC1 to enhance host resistance to Mycobacterium tuberculosis
Published 2024-10-01“…Mechanistically, we demonstrated that SIRT7 limits Mtb infection by directly interacting with and activating RAC1, through which cytoskeletal remodeling is modulated. Therefore, we concluded that SIRT7, in its role regulating cytoskeletal remodeling through RAC1, is critical for host responses during Mtb infection and proposes a potential target for tuberculosis treatment.IMPORTANCETuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a significant global health issue. …”
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In vitro antibacterial efficacy of a novel chicken-derived Bacillus subtilis GX15 strain and its protective mechanisms in mice challenged by Salmonella enterica serovar typhymurium
Published 2025-07-01“…Abstract Background The escalating issue of bacterial resistance, coupled with stringent restrictions on antibiotic use in many countries, has prompted the search for alternative strategies to combat bacterial infections. …”
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Ginsenoside Rb1 and berberine synergistically protect against type 2 diabetes mellitus via GDF15/HAMP pathway throughout the liver lobules: Insights from spatial transcriptomics an...
Published 2025-05-01“…Type 2 diabetes mellitus (T2DM) is a significant public health issue with high morbidity and mortality. Ginsenoside Rb1 (Rb1) and berberine (BBR), the main bioactive compounds of Panax ginseng and Coptis chinensis, respectively, are known for their hypoglycemic effects. …”
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Association between the composite dietary antioxidant index and cardiovascular-kidney-metabolic syndrome among U.S. adults: evidence from NHANES 2007–2018
Published 2025-07-01“…ObjectiveCardiovascular-kidney-metabolic (CKM) syndrome is a major public health issue worldwide. However, direct evidence on dietary modulators in CKM syndrome is lacking. …”
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Injectable Nanocomposite Hydrogel for Accelerating Diabetic Wound Healing Through Inflammatory Microenvironment Regulation
Published 2025-02-01“…This hydrogel effectively suppresses inflammatory responses, modulates the polarization of macrophages towards the M2 phenotype, and promotes angiogenesis, thus fostering a favorable immune microenvironment for skin regeneration. …”
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Astrocytic NLRP3 cKO mitigates depression-like behaviors induced by mild TBI in mice.
Published 2025-02-01“…Background: Reports indicate that depression is a common mental health issue following traumatic brain injury (TBI). Our prior research suggests that Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)-related neuroinflammation, modulated by glial cells such as astrocytes, is likely to play a crucial role in the progression of anxiety and cognitive dysfunction. …”
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