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Termination sequence between an inducible promoter and ubiquitous chromatin opening element (UCOE) reduces gene expression leakage and silencing
Published 2025-04-01“…It also suggests investigating how termination of transcription modulates gene silencing as a novel design parameter. …”
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Exosome-Loaded GelMA Hydrogel as a Cell-Free Therapeutic Strategy for Hypertrophic Scar Inhibition
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Gut microbiota-derived gamma-aminobutyric acid improves host appetite by inhibiting satiety hormone secretion
Published 2024-10-01“…ABSTRACT Globally, appetite disorders have become an increasingly prominent public health issue. While short-term appetite loss may seem relatively harmless, prolonged instances can lead to serious physical and mental damage. …”
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FOLR1-Targeted Oxygen-Delivering Nanosomes Enhance Chemo-Induced Apoptosis in Hypoxic Cancer
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Development of a novel macroscopic regulation and microscopic intervention mode nanosystem for osteoporosis treatment
Published 2025-06-01“…Osteoporosis is a widespread global health issue characterized by progressive bone loss and impaired regeneration, largely due to an acidic bone microenvironment that suppresses osteoblast differentiation and fails to initiate effective osteogenesis. …”
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Flexible Glass Hybridized Colloidal Quantum Dots for Gb/s Visible Light Communications
Published 2018-01-01“…The flexible glass/CQD format addresses the issue of limited modulation speed of typical phosphor-converted LEDs while enhancing the photostability of the color converters and facilitating their integration with the μLEDs. …”
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Clinical trial to compare safety and tolerability between intravenous infusion and bolus intravenous injection of ApTOLL in healthy volunteers
Published 2025-03-01“…ApTOLL, a new modulator of Toll-like receptor 4, has demonstrated safety and efficacy in healthy subjects and in stroke patients; however, the route of administration used so far (30 min infusion) can potentially be an issue in the acute stroke units where “time is brain.” …”
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Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice
Published 2025-07-01“…Abstract Sepsis is a severe global health issue with high mortality rates, and sepsis-associated encephalopathy (SAE) further exacerbates this risk. …”
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Smart injectable hydrogels for periodontal regeneration: Recent advancements in biomaterials and biofabrication strategies
Published 2025-06-01“…Hence, the drastic increase in dental implants for periodontitis has become a severe clinical issue. Injectable hydrogel based on extracellular matrix (ECM) is highly biocompatible and tissue-regenerative with tailor-made mechanical properties and high payload capacity for in situ delivery of bioactive molecules to treat periodontitis. …”
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Penerapan Importance Performance Analysis (IPA) pada Evaluasi Keberlanjutan Penggunaan e-filing untuk Pelaporan Pajak Perorangan
Published 2022-02-01“…E-filing merupakan bentuk penerapan sistem Modul Penerimaan Negara Generasi Kedua (MPN G2) yang mulai diterapkan pada tahun 2007. …”
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Silicon and heavy metal dynamics in soil-rice systems: A taihu lake plain case study on silicon depletion
Published 2025-09-01“…This study addresses the critical issue of heavy metal contamination (Ni, Cu, As, Cd, Pb) in rice cultivation, with particular focus on silicon-deficient paddy soils in the Taihu Lake Plain, where SiNaAc is 87.97 mg kg−1. …”
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