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Structural bioinformatics for rational drug design
Published 2025-01-01“…Key techniques, including structure- and ligand-based virtual screening, molecular dynamics simulations, and artificial intelligence–driven models are allowing researchers to explore vast chemical spaces, investigate molecular interactions, predict binding affinity, and optimize drug candidates with unprecedented accuracy and efficiency. …”
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The utility of dynamic forest structure from GEDI lidar fusion in tropical mammal species distribution models
Published 2025-05-01“…Moreover, as we examined predictor importance and partial dependence, the utility of GEDI Fusion predictors in hindcast models was evident in regards to ecological interpretability. …”
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186
Recognition of Underwater Engineering Structures Using CNN Models and Data Expansion on Side-Scan Sonar Images
Published 2025-02-01“…Side-scan sonar (SSS) is a critical tool in marine geophysical exploration, enabling the detection of seabed structures and geological phenomena. However, the manual interpretation of SSS images is time-consuming and relies heavily on expertise, limiting its efficiency and scalability. …”
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Deterministic and Stochastic Machine Learning Classification Models: A Comparative Study Applied to Companies’ Capital Structures
Published 2025-01-01“…Notably, all models delivered statistically similar results in the test sample, emphasizing the need to balance performance, simplicity, and interpretability. …”
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188
Integrating Large Language Models and Optimization in Semi- Structured Decision Making: Methodology and a Case Study
Published 2024-12-01“…Semi-structured decisions, which fall between highly structured and unstructured decision types, rely on human intuition and experience for the final choice, while using data and analytical models to generate tentative solutions. …”
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THE VELOCITY STRUCTURE OF THE UPPER MANTLE AND REGIONAL DEEP THERMODYNAMICS OF THE BAIKAL RIFT ZONE
Published 2015-10-01Get full text
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Advancing AI Interpretability in Medical Imaging: A Comparative Analysis of Pixel-Level Interpretability and Grad-CAM Models
Published 2025-02-01“…This study introduces the Pixel-Level Interpretability (PLI) model, a novel framework designed to address critical limitations in medical imaging diagnostics by enhancing model transparency and diagnostic accuracy. …”
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191
Simplified FE-Based Post-Earthquake Vulnerability Assessment of a Partially Collapsed Historic Mosque
Published 2025-05-01“…This study presents a simulation-based approach to rapidly assess the seismic vulnerability of this partially damaged historic masonry structure. Due to the complexity and urgent condition of such heritage buildings, a simplified finite element (FE) modeling methodology is employed to evaluate structural behavior and support immediate stabilization decisions. …”
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192
Prioritization and Ranking of Phases for the Management of the Construction Project of the LNG Plant Production Line
Published 2017-04-01Subjects: Get full text
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193
Structure of loop space at finite N
Published 2025-06-01“…We extend this analysis to multi-matrix models at finite N. Using the Molien-Weyl formula, we compute partition functions for various multi-matrix models at different N and interpret them through trace relations. …”
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194
The Postdramatic Structure of Müller’s The Hamlet Machine
Published 2022-12-01“…Müller’s The Hamlet Machine does not correspond to the formal structure of conventional theater known as drama. As a result of the discussions on theatricality, the theater sign system and the organization model of dramatic structure were revised. …”
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Performance Prediction of the Gearbox Elastic Support Structure Based on Multi-Task Learning
Published 2025-05-01“…Neural networks offer a powerful means of capturing and interpreting the intricate associations linking structural parameters with performance metrics. …”
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Effect of Soil Saturation On Seismic Performance of A Structure: A Numerical Approach
Published 2019-04-01“…More specifically, this paper examinesthe effect of the soil saturation leveltaking into account of soil-structureinteraction (SSI) on the structural response. For this purpose, a twodimensional (2D) finite element model was developed with Mohr-Coulomb failurecriterion under plane-strain conditions using geotechnical finite element codePLAXIS. …”
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Competition in mixed Scots pine and Pyrenean oak stands modifies allometry and partially affects biomass allocation during early stand development
Published 2025-07-01“…Here, we destructively sampled 90 trees and then applied ANCOVA to quantify the direct effects of competition on tree structural attributes and biomass allocation. Additionally, we used structural equation modeling (SEM) to evaluate the indirect effects of competition. …”
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PhyBaSE: A Bayesian structural equation model approach to causal inference in phylogenetic comparative analyses
Published 2025-06-01“…Abstract One of the main limitations of phylogenetic comparative analyses is that associations between traits can only be interpreted as correlations. Here, we present a novel Bayesian structural equation model (PhyBaSE) which allows us to disentangle direct from indirect relationships among variables to propose potential causal hypotheses while accounting for phylogenetic non‐independence. …”
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