The RNA-Binding Protein KSRP Modulates Cytokine Expression of CD4+ T Cells by Rudolf Käfer, Lisa Schmidtke, Katharina Schrick, Evelyn Montermann, Matthias Bros, Hartmut Kleinert, Andrea Pautz

“…As KSRP regulates innate immune responses, for instance by the modulation of type I interferon mRNA stability, we were interested whether knockdown of the protein (KSRP-/-) interferes with T cell activation and polarization. …”
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Whole body and hematopoietic cell-specific deletion of G-protein coupled receptor 65 (GPR65) improves insulin sensitivity in diet-induced obese mice by Yingjiang Zhou, EunJu Bae, Simon S. Hoffman, Da Young Oh, Gordon I. Smith, Samuel Klein, Saswata Talukdar

“…Objective: Acidic extracellular microenvironments, resulting from enhanced glycolysis and lactic acid secretion by immune cells, along with metabolic acidosis may interfere with the insulin signaling pathway and contribute to the development of insulin resistance. …”
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Tandospirone prevents anesthetic-induced respiratory depression through 5-HT1A receptor activation in rats by Meng-ran Song, Ming-zhi Huang, Wei-jie Tao, Zheng Yong, Rui-bin Su

“…Treatment with specific antagonists or respiratory stimulants can reverse respiratory depression caused by anesthetics; however, they also interfere with the sedative effects of anesthetics. …”
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Tumor Necrosis Factor and Interleukin-1β Modulate Synaptic Plasticity during Neuroinflammation by Francesca Romana Rizzo, Alessandra Musella, Francesca De Vito, Diego Fresegna, Silvia Bullitta, Valentina Vanni, Livia Guadalupi, Mario Stampanoni Bassi, Fabio Buttari, Georgia Mandolesi, Diego Centonze, Antonietta Gentile

“…However, when cytokines dramatically increase, establishing a status of neuroinflammation, the synaptic action of such molecules remarkably interferes with brain circuits of learning and cognition and contributes to excitotoxicity and neurodegeneration. …”
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Variations in conventional and non-conventional semen characteristics of selected rabbit breeds by Eva Tvrdá, Filip Benko, Michal Ďuračka, Anton Kováčik, Jakub Vozaf, Andrea Svoradová, Jaromír Vašíček, Andrej Baláži, Peter Supuka, Simona Kunová, Jana Žiarovská, Miroslava Kačániová, Peter Chrenek

“…., Micrococcus spp. and Acinetobacter spp. Significantly increased levels of alanine transaminase and creatinine (Crea) were found in New Zealand rabbits in comparison to the Liptov Baldspotted breed (p < 0.001). …”
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Integrative causal inference illuminates gene-environment interactions linking endocrine disruptors to female infertility by Yanggang Hong, Zhuoyi Du, Jiajun Li, Yi Wang, Yirong Wang, Wanyi Shu, Qinxi Shen, Feng Chen, Sisi Li

“…Among environmental contributors, endocrine-disrupting chemicals (EDCs), which interfere with hormonal systems, have gained attention for their potential impact on reproductive health. …”
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Chilling and drought stresses in maize: Mitigation strategies and potential management opportunities by Ambreen FATIMA, Athar MAHMOOD, Hussam F. Najeeb ALAWADI, Muhammad Mansoor JAVAID, Hafiz Bashir AHMAD, Jameel Mohammed AL-KHAYRI, Mohammed Ibrahim ALDAEJ, Othman AL-DOSSARY, Bader ALSUBAIE, Wael Fathi SHEHATA

“…Conversely, drought stress, which is brought on by insufficient water availability, interferes with essential functions like the roots' ability to absorb water and nutrients, increases transpiration losses, causes the leaves to roll, and delays senescence.  …”
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Sustainable forest management: success and challenges in Ethiopia by Rusha Begna Wakweya

“…Generally, the most important state led FLR initiatives aimed at reducing forest and land degradation in Ethiopia include engaging communities in the management of state-owned natural forests through participatory forest management (PFM), assisting natural regeneration in degraded lands by excluding human and animal interference through the establishment of area enclosures/enclosures (AEs), and mobilization of communities and engaging them in soil and water conservation works and tree planting campaigns through sustainable land management programs and the recent Green Legacy Initiative (SLM-GLI) to promote tree planting and increase national forest cover. …”
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Interpreting high levels of unfolded Von Willebrand Factor in patients with the antiphospholipid syndrome by Romy de Laat-Kremers, Shengshi Huang, Shengshi Huang, Hugo ten Cate, Hugo ten Cate, Marisa Ninivaggi, Bas de Laat, Bas de Laat, Katrien Devreese, Katrien Devreese

“…IntroductionUnfolded Von Willebrand Factor (VWF) is increased in thrombotic pathologies such as myocardial infarction. …”
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From Antiretroviral to Antibacterial: Deep-Learning-Accelerated Repurposing and In Vitro Validation of Efavirenz Against Gram-Positive Bacteria by Ezzeldin Saleh, Omar A. Soliman, Nancy Attia, Nouran Rafaat, Daniel Baecker, Mohamed Teleb, Abeer Ghazal, Ahmed Noby Amer

“…EFV showed restored sensitivity of β-lactams against Methicillin-resistant <i>S. aureus</i> (MRSA). It increased the effectiveness of antibiotics tested against Methicillin-sensitive <i>S. aureus</i> (MSSA). …”
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Autism Spectrum Disorder, Oral Implications, and Oral Microbiota by Emiliana D’Angelo, Fausto Fiori, Giuseppe A. Ferraro, Assunta Tessitore, Luca Nazzaro, Rosario Serpico, Maria Contaldo

“…<b>Results:</b> Individuals with ASD face unique oral health challenges, including injuries from self-injurious behaviors and increased sensory sensitivity, which complicate oral hygiene and care. …”
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Gal-3 blocks the binding between PD-1 and pembrolizumab by Henrik Schmidt, Torben Steiniche, Bent Deleuran, Malene Hvid, Morten Aagaard Nielsen, Stinne Ravn Greisen, Mia Bendix, Kathrine Pedersen, Nina Haunstrup Jensen, Jakob Hauge Mikkelsen, Taner Drace, Thomas Boesen

“…Soluble PD-1 levels in plasma increased after treatment with pembrolizumab and correlated with disease progression.Conclusion We demonstrate that the interaction between PD-1 and Gal-3 interferes with the binding of pembrolizumab, supporting that an immune suppression induced by Gal-3 in the tumor microenvironment cannot be rescued by pembrolizumab.…”
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Comparative genomics analyses of Actinobacteriota identify Golgi phosphoprotein 3 (GPP34) as a widespread ancient protein family associated with sponge symbiosis by Cláudia Ferreira, Ilia Burgsdorf, Tzipora Perez, Gustavo Ramírez, Maya Lalzar, Dorothée Huchon, Laura Steindler

“…Results Our analysis uncovered several differences between symbiotic and free-living bacteria, including an increased abundance of genes encoding prokaryotic defense systems (PDSs) and eukaryotic-like proteins (ELPs) in symbionts. …”
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The sphingosine‐1‐phosphate signaling pathway (sphingosine‐1‐phosphate and its receptor, sphingosine kinase) and epilepsy by Lin Wang, Qingxia Kong, Xinyi Leng, Howan Leung, Yang Li

“…The use of newer antiepileptic drugs has increased, but this has not improved overall outcomes. …”
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Biochanin a modulates steroidogenesis and cellular metabolism in human granulosa cells through TAS2Rs activation: a spotlight on ovarian function by Francesca Paola Luongo, Sofia Passaponti, Alesandro Haxhiu, Irene Ortega Baño, Rosetta Ponchia, Giuseppe Morgante, Paola Piomboni, Alice Luddi

“…Abstract Background Endocrine-disrupting chemicals (EDCs) interfere with the endocrine system and negatively impact reproductive health. …”
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Assessing the success of breeding maize inbred lines with contrasting diferulate concentrations by Ana López-Malvar, Rosa Ana Malvar, Ana Butrón, Xose Carlos Souto, Rogelio Santiago

“…Abstract Background The crosslinking of maize cell wall components, particularly mediated by the formation of ferulic acid dimers or diferulates, has been associated with important crop valorization traits such as increased pest resistance, lower forage digestibility, or reduced bioethanol production. …”
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Efficient gas extraction technology via surface wells in goaf areas of deep outburst-prone coal mines by YANG Jidong, TONG Yanjun

“…Surface well extraction did not interfere with the normal operation of the high-extraction roadway. …”
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CsrA-mediated regulation of a virulence switch in Acinetobacter baumannii by Raja Singh, María Pérez-Varela, Jennifer M. Colquhoun, Carsten Kröger, Fergal J. Hamrock, Ali Shaibah, Ellen L. Neidle, Philip N. Rather

“…Individual deletions of each sRNA increased the frequency of VIR-O to AV-T switching, with loss of CsrB giving the highest increase at 2.4-fold. …”
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Metastatic papillary thyroid carcinoma presenting with elevated serum levels of carbohydrate antigen 19-9 (CA19-9): a case report by Minoru Kihara, Akira Miyauchi, Mitsuyoshi Hirokawa, Makoto Fujishima, Hiroo Masuoka, Takuya Higashiyama, Naoyoshi Onoda, Yasuhiro Ito, Akihiro Miya

“…The patient’s serum Tg levels increased progressively during follow-up and his serum TgAb was negative. …”
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TACTICS OF THE DENTIST DURING ORTHOPEDIC TREATMENT WITH DIFFERENT PROSTHESIS DESIGNS IN NON-STANDARD CLINICAL SITUATIONS by V.M. Dvornyk, H.M. Kuz, O.I. Teslenko, O.V. Dobrovolska, V.S. Kuz, K.Yu. Nedashkivskyi, K.V. Marchenko

“…Correction of the dentures to eliminate areas of increased pressure is performed on the day of denture placement, as well as repeatedly during follow-up visits. …”
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