Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy by Peter Illes, Patrizia Rubini, Henning Ulrich, Hai‐Yan Yin, Yong Tang

“…However, on the opposite, the increased stimulation of the microglial/astrocytic P2X7R‐channel by ATP causes neuroinflammation and in consequence depressive‐like behavior. …”
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Antiphospholipid Antibodies Bind ATP: A putative Mechanism for the Pathogenesis of Neuronal Dysfunction by J. Chapman, L. Soloveichick, S. Shavit, Y. Shoenfeld, A. D. Korczyn

“…Furthermore, addition of β2-GPI to aPL IgG significantly increased the amount of aPL binding to an ATP column. …”
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LINE-1 transposition into murine Thyroglobulin results in congenital thyroid dysplasia. by Wendy J Bailey, Bart M G Smits, Zoltan Erdos, John M Gaspar, Pamela Lane, Sabu Kuruvilla, Thomas W Rosahl, Douglas Thudium, Jingzhou Wang, Warren E Glaab, Melissa MacGowan, Heather Multari, Christine Cumo, Adam Navis, Thomas Forest

“…In addition, serum Thyroid Stimulating Hormone (TSH) level was strongly increased in homozygotes at 6-8 months of age, consistent with hypothyroidism. …”
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Multi-omics insights into the mechanisms of muscle damage induced by molybdenum exposure in goats by Xinhong Zhou, Xiaoyun Shen

“…Molybdenum (Mo) is an essential trace element, yet excessive intake can result in toxicity, adversely affecting animal health and food safety. Due to increasing environmental Mo contamination from industrial and agricultural activities, understanding its toxic effects on livestock is of global concern. …”
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Antiangiogenic activity of 2-deoxy-D-glucose. by Jaime R Merchan, Krisztina Kovács, Jaclyn W Railsback, Metin Kurtoglu, Yuqi Jing, Yolanda Piña, Ningguo Gao, Timothy G Murray, Mark A Lehrman, Theodore J Lampidis

“…Since glucose uptake and metabolism are increased to meet this energy need, the effects of the glycolytic inhibitor 2-deoxy-D-glucose (2-DG) on in vitro and in vivo angiogenesis were investigated.…”
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NLRP3 overexpression exacerbated synovium tissue degeneration in juvenile collagen-induced arthritis by Fater A. Khadour, Younes A. Khadour, Tao Xu

“…Moreover, we also found that increases in the expression of NLRP3 impairs autophagy capacity and increases activation of the pyroptosis pathway in the synovium of the juvenile CIA rats. …”
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Non-Thermal Dielectric Barrier Discharge (DBD) Effects on Proliferation and Differentiation of Human Fibroblasts Are Primary Mediated by Hydrogen Peroxide. by Julian Balzer, Kiara Heuer, Erhan Demir, Martin A Hoffmanns, Sabrina Baldus, Paul C Fuchs, Peter Awakowicz, Christoph V Suschek, Christian Opländer

“…In addition, the total number of myofibroblasts was reduced, whereas in contrast, the myofibroblast frequency was significantly increased 12 days after DBD treatment or exposure to DBD-treated PBS. …”
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GM-1111 reduces radiation-induced oral mucositis in mice by targeting pattern recognition receptor-mediated inflammatory signaling. by Abigail Pulsipher, Justin R Savage, Thomas P Kennedy, Kavita Gupta, Benjamin G Cuiffo, Stephen T Sonis, Won Yong Lee

“…The lesions showed selective increases in PRR and pro-inflammatory cytokine gene expression levels. …”
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Maternal exposure to an environmentally relevant dose of triclocarban results in perinatal exposure and potential alterations in offspring development in the mouse model. by Heather A Enright, Miranda J S Falso, Michael A Malfatti, Victoria Lao, Edward A Kuhn, Nicholas Hum, Yilan Shi, Ana Paula Sales, Kurt W Haack, Kristen S Kulp, Bruce A Buchholz, Gabriela G Loots, Graham Bench, Kenneth W Turteltaub

“…Our findings suggest that early-life exposure to TCC may interfere with lipid metabolism and could have implications for human health.…”
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In vitro Allelopathic Potential of Leaf Water Extracts of Plantago lanceolata and P. major on the Germination of Some Crops by Onur Yaraş, Nadim Yılmazer

“…Alongside increasing productivity in plant production, reducing crop losses has become a major focus for the struggle of today’s man against hunger. …”
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The impact of intermittent preventive treatment in school aged children with dihydroartemisinin piperaquine and artesunate amodiaquine on IgG response against six blood stage Plasm... by Eric Lyimo, Geofrey Makenga, Louise Turner, Thomas Lavstsen, John P A Lusingu, Jean-Pierre Van Geertruyden, Daniel T R Minja, Christian W Wang, Vito Baraka

“…Breadth of malaria antigen recognition increased significantly during and after the intervention phases and did not differ between the study groups (Trend test: DP, z-score = 5.92, p < 0.001, ASAQ, z-score = 6.64, p < 0.001 and control, z-score = 5.85, p < 0.001). …”
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Quantifying Zinc Contamination from Laboratory Syringes by Sarah G. Lindgren, Laura J. Sakol, Monica Hoover, Timothy M. Raymond, Dabrina D. Dutcher

“…The results, which ranged from less than 20 to over 600 μg L⁻¹, revealed increased zinc concentration at both extreme pH values, while remaining lower but measurable at neutral pH levels. …”
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RAB5 is a host dependency factor for the generation of SARS-CoV-2 replication organelles by Yuexuan Chen, Susanne Klute, Konstantin Maria Johannes Sparrer, Ruth Serra-Moreno

“…ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains a threat due to the emergence of variants with increased transmissibility and enhanced escape from immune responses. …”
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Physicochemical and sensory properties of honey powder from different climatic regions by Mona Vosoghi, Shima Yousefi, Masoud Honarvar

“…The conversion of honey into powder through spray drying led to a notable increase in hydroxymethylfurfural (HMF), attributed to the high processing temperatures, and a significant decline in diastase activity, likely due to the presence of maltodextrin, which interferes with enzymatic activity, likely through dilution and structural modifications. …”
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The impact of autoimmune thyroid disease on cognitive and psychiatric disorders: focus on clinical, pre-clinical and molecular studies by Agnieszka Piekiełko-Witkowska, Monika K Duda, Joanna Bogusławska, Urszula Mackiewicz

“…The growing body of evidence suggests that AITD can interfere with brain function. Here, we review the impact of AITD on cognition, mood, and psychiatric disorders by analysing data from clinical, animal, ex vivo and in vitro studies to reveal the molecular mechanisms by which AITD affects brain function. …”
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Systematic review of electron transfer study in DNA relevant to Parkinson’s disease and scanning tunneling microscopy by Muhammad Hanif Che Lah, Mohammed Faruque Reza, Shaharum Shamsuddin, Isao Watanabe, Jafri M. Abdullah

“…Results From the thirty studies identified, PD appears to be caused by various causes, including increased levels of cytochrome c, reactive oxygen species produced by the mitochondria, dysfunction of complex I that interferes with the electron transfer process, and mitochondrial dysfunction triggered by PINK1 mutation. 6.7% of prior research has focused on utilizing DNA as a specific sample for investigating electron transfer in synthetic DNA through the use of STM. …”
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Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis. by Vino T Cheriyan, Ying Wang, Magesh Muthu, Shazia Jamal, Di Chen, Huanjie Yang, Lisa A Polin, Adi L Tarca, Harvey I Pass, Q Ping Dou, Sunita Sharma, Anil Wali, Arun K Rishi

“…DSF-Cu inhibited growth of the murine as well as human MPM cells in part by increasing levels of ubiquitinated proteins. DSF-Cu exposure stimulated apoptosis in MPM cells that involved activation of stress-activated protein kinases (SAPKs) p38 and JNK1/2, caspase-3, and cleavage of poly-(ADP-ribose)-polymerase, as well as increased expression of sulfatase 1 and apoptosis transducing CARP-1/CCAR1 protein. …”
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Interleukin-1 and interferon-γ orchestrate β-glucan-activated human dendritic cell programming via IκB-ζ modulation. by Marco Cardone, Amiran K Dzutsev, Hongchuan Li, Nicolas Riteau, Franca Gerosa, Kevin Shenderov, Robin Winkler-Pickett, Lisa Provezza, Elena Riboldi, Robert M Leighty, Selinda J Orr, Folkert Steinhagen, Mark D Wewers, Alan Sher, Stephen K Anderson, Romina Goldszmid, Daniel W McVicar, Lyudmila Lyakh, Giorgio Trinchieri

“…Interferon (IFN)-γ interferes with the IL-1/IκB-ζ axis in β-glucan-activated DCs and promotes T cell-mediated immune responses with increased release of IFN-γ and IL-22, and diminished production of IL-17. …”
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Vertical distribution and factors influencing tropical forest soil magnetic susceptibility in Xishuangbanna, Southwest China by Xiaoling Zhang, Xiaoling Zhang, Xiaoling Zhang, Haidong Wang, Haidong Wang, Hongzhan Liu, Hongzhan Liu, Haixia Li, Haixia Li, Haixia Li, Yucheng Shi, Guangyu Zheng, Fengrui Li, Daxiang Liu, Xiaoping Jiang, Erhui Ren, Gangqiang Li

“…In soil systems, the relationship between environmental factors and magnetic susceptibility is complex and interferes with the interpretation of magnetic susceptibility data. …”
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Exogenous prion-like proteins and their potential to trigger cognitive dysfunction by Jofre Seira Curto, Adan Dominguez Martinez, Genis Perez Collell, Estrella Barniol Simon, Marina Romero Ruiz, Berta Franco Bordés, Paula Sotillo Sotillo, Sandra Villegas Hernandez, Maria Rosario Fernandez, Natalia Sanchez de Groot

“…Based on these findings, we rationally designed a set of synthetic prion-like sequences that form amyloid fibrils, interfere with amyloid-beta-peptide aggregation, and trigger prion propagation when introduced in the yeast Sup35 model. …”
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