The Fanconi anemia group C protein interacts with uncoordinated 5A and delays apoptosis. by FengFei Huang, Manel Ben Aissa, Audrey Magron, Caroline C Huard, Chantal Godin, Georges Lévesque, Madeleine Carreau

“…FANCC modulates cell sensitivity to UNC5A-mediated apoptosis; we observed reduced UNC5A-mediated apoptosis in the presence of FANCC and increased apoptosis in FANCC-depleted cells. Our results show that FANCC interferes with UNC5A's functions in apoptosis and suggest that FANCC may participate in developmental processes through association with the dependence receptor UNC5A.…”
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Nanoparticles and female reproductive toxicity: A review by C. Kumar, R. K. Sharma

“…Due to anthropogenic methods of nanoparticles synthesis, the applications have increased dramatically within the last century. This increase in consumption has led to increase in potential toxicity of nanoparticles especially in reproductive system. …”

PENERAPAN IPTEK PADA INDUSTRI TAHU KHAS BANDUNGAN KABUPATEN SEMARANG by Muhammad Khumaedi, Sudarman Sudarman, Siti Harnina Bintari

“…Outputs management aspects: 1) bookkeeping financial / business better, and 2) further increased marketing / marketing a wider range.…”
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Chronic stress inhibits weight gain and decreases beta-hydroxybutyrate levels and glucose tolerance in female BALB/c fed a high-fat ketogenic diet by Ana L. Cantú-Ruiz, Diana Caballero-Hernández, Isaias Gutierrez-Leal, Ana C. Martínez-Torres, Ricardo Gomez-Flores, Patricia Tamez-Guerra, Reyes Tamez-Guerra, Cristina Rodríguez-Padilla

“…Results Levels of β-hydroxybutyrate increased in the KD group in both sexes. However, under stress, the increase in ketone bodies was lower in female mice. …”
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Hydatid Cyst Protoscolices Induce Cell Death in WEHI-164 Fibrosarcoma Cells and Inhibit the Proliferation of Baby Hamster Kidney Fibroblasts In Vitro by Hossein Yousofi Darani, Narges Soozangar, Soliman Khorami, Fatomeh Taji, Mortaza Yousofi, Hedayatollah Shirzad

“…Both in vitro and in vivo models have demonstrated that some parasites can interfere with tumor cell growth. The present study investigates the anticancer activity of hydatid cyst protoscolices on WEHI-164 fibrosarcoma cells and baby hamster kidney (BHK) fibroblast cells in vitro. …”
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Tergitol-15-S-9 inactivates SARS-CoV-2 and boosts immunoassay signals by Michael G Berg, Eitan Israeli, Erin Quaco, Gavin A Cloherty, Philip M Hemken

“…Inactivation of SARS-CoV-2 virus is necessary to mitigate risk but may interfere with diagnostic assay performance. We examined the effect of heat inactivation on a prototype SARS-CoV-2 antigen immunoassay run on the ARCHITECT automated analyzer. …”
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Mechanisms underlying delayed loss of HBeAg and HBV DNA following HBsAg seroclearance in PEG-IFNα treated patients of chronic hepatitis B by Bei Jiang, Guiwen Guan, Kaitao Zhao, Zhiqiang Gu, Lin Wang, Weilin Gu, Minghui Li, Yuchen Xia, Xiangmei Chen, Yifei Guo, Jiming Zhang, Zhenhuan Cao, Man-fung Yuen, Fengmin Lu

“…In vitro experiments demonstrated that introduced SP1/SP2 inactive mutations would enhance PC/BCP transcriptional activity by a mechanism known as adjacent transcriptional interference. Furthermore, the deletion of L-HBsAg facilitated intracellular cccDNA replenishment.Conclusion This study elucidates that under IFNα treatment and low viral load, transcriptional suppression of SP1/SP2 promoters through mutations and/or epigenetic changes would favour the maintenance of sustain chronic HBV infection, via enhancing the transcription activity of BCP to promote cccDNA replenishment.Impact and implications In clinical practice with IFNα antiviral treatment for CHB patients, a “paradoxical” phenomenon is observed where serum HBsAg disappears while HBV DNA or/and HBeAg remains at low positive levels, with delayed disappearance. …”
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Energy Failure Mechanism and Bedding Effect of Soaked Coal Under Uniaxial Compression by Xiaoling LIU, Zetian ZHANG, Ru ZHANG, Zhiguo CAO, Li REN, Ziwan SUN, Ersheng ZHA

“…Pure water is used for immersion in the experiment to avoid the interference of special element composition with the test results. …”
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Immunity Against <i>Mycobacterium avium</i> Induced by DAR-901 and BCG by Getahun Abate, Krystal A. Meza, Chase G. Colbert, Octavio Ramos-Espinosa, Nancy J. Phillips, Christopher S. Eickhoff

“…<b>Results</b>: Our results showed that (i) DAR-901 induced cross-reactive immunity to MAC to a similar level as BCG, (ii) DAR-901 and BCG protected against aerosol MAC challenge, (iii) mucosal BCG vaccination, compared to systemic BCG and DAR-901 vaccinations, provided the best protection against MAC challenge, (iv) BCG vaccination did not interfere with anti-MAC activities of clarithromycin, (v) BCG-vaccinated mice had increased inflammation and increased frequencies of activated CD4 and CD8 T cells following MAC infection, and (vi) doxycycline treatment of tetR BCG-vaccinated mice decreased lung BCG CFU without affecting MAC immunity. …”
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Opposite Trends in the Northern Hemisphere Stratosphere Between Mid‐Winter and Early Spring Linked to Surface Temperature Anomalies by Gwendal Rivière, Fabio D’Andrea, Daniela I. V. Domeisen, Alice Portal

“…This is associated with an increased Northern Hemisphere annular mode in March in the stratosphere and the troposphere. …”
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A high‐affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain by Nikolaj R Christensen, Marta De Luca, Michael B Lever, Mette Richner, Astrid B Hansen, Gith Noes‐Holt, Kathrine L Jensen, Mette Rathje, Dennis Bo Jensen, Simon Erlendsson, Christian RO Bartling, Ina Ammendrup‐Johnsen, Sofie E Pedersen, Michèle Schönauer, Klaus B Nissen, Søren R Midtgaard, Kaare Teilum, Lise Arleth, Andreas T Sørensen, Anders Bach, Kristian Strømgaard, Claire F Meehan, Christian B Vægter, Ulrik Gether, Kenneth L Madsen

“…As an alternative, we developed a cell‐permeable, high‐affinity (~2 nM) peptide inhibitor, Tat‐P4‐(C5)2, of the PDZ domain protein PICK1 to interfere with increased AMPAR expression. The affinity is obtained partly from the Tat peptide and partly from the bivalency of the PDZ motif, engaging PDZ domains from two separate PICK1 dimers to form a tetrameric complex. …”
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Lingual and Maxillary Labial Frenuloplasty with Myofunctional Therapy as a Treatment for Mouth Breathing and Snoring by Chirag Govardhan, Janine Murdock, Leyli Norouz-Knutsen, Sanda Valcu-Pinkerton, Soroush Zaghi

“…The patient was also observed to have increased compliance with myofunctional therapy exercises. …”
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Root cause analysis of noise transfer in an entire tractor system using multi-layer operational transfer path analysis by Hyun-Woo Han, Min-Woo Kang, Seong-Hyun Lee, Yun-Ho Seo, Seung-Je Cho, Jeong-Gil Kim, Young-Joo Kim, Young-Jun Park

“…Tractor noise and vibrations adversely affect the health of operators, reduce work efficiency, and interfere with the creation of a comfortable working environment. …”
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Cell type-specific neuroprotective activity of untranslocated prion protein. by Elena Restelli, Luana Fioriti, Susanna Mantovani, Simona Airaghi, Gianluigi Forloni, Roberto Chiesa

“…A cyclopeptolide that interferes with the correct insertion of the PrP signal sequence into the translocon increased the amount of untranslocated PrP in cortical and hippocampal cells, and induced its synthesis in cerebellar neurons. …”
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Do we miss half of the injuries sustained during rape because we cannot see them? An overview of the use of toluidine blue tissue stain in the medical assessment of rape cases by J. M. Kotzé, H. Brits

“…McCauley found that the detection of vaginal lacerations increased from one in 24 to 14 in 24 in reported adult rape cases when toluidine blue was used. …”
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Organic compounds with high Ni content: Effects on soil and strawberry production by Luís F. Roveda, Francine L. Cuquel, Antônio C. V. Motta, Vander de F. Melo

“…The mineral Ni source was almost 15-fold more effective than the organic source at increasing leaf Ni content. Application of OC caused an increase of organic matter, Ca, sum of bases, cation exchange capacity, base saturation, Zn, Mn, and Cu, but reduced the levels of Mg in soil.…”
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Ambiguity in the Margins of the Text by Sidi Mohamed LAKHDAR BARKA

“…Subsequently to a policy of ‘democratization’ of education in Algeria, the potential of readers has massively increased, inducing new needs with new reading habits, often mimetic. …”
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Phosphate and potassium fertilization on agronomic and physico-chemical characteristics and bioactive compounds of eggplant by Luciene A. de Oliveira, Ernani C. da Silva, Lanamar de A. Carlos, Gabriel M. Maciel

“…Phenolic compounds and anthocyanins are some of the compounds that interfere in this antioxidant capacity and may be influenced by the mineral nutrition of the plant. …”
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The prevalence of exercise-induced asthma among school children by Bhekiwe F. Mtshali, Kebogile E. Mokwena

“…The prevalence of EIA is reported to be on the increase among school children worldwide. The aim of this study was to indicate EIA prevalence among primary-school children in South Africa. …”
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Community care of individuals at risk of suicide: the Life Promotion Clinic model by Kairi Kolves, Urska Arnautovska, Angelo De Gioannis, Diego De Leo

“…We can conclude that establishing a specialist service for treatment of individuals at increased risk for suicide requires consideration of both patient and clinicians needs. …”
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