Effects of antagonistic network-targeted tDCS on brain co-activation patterns depends on the networks’ electric field: a simultaneous tDCS-fMRI study by Hechun Li, Hongru Shi, Sisi Jiang, Changyue Hou, Haonan Pei, Hanxi Wu, María Luisa Bringas Vega, Gang Yao, Dezhong Yao, Cheng Luo

“…Material and method: The current study utilized simultaneous network-targeted transcranial direct current stimulation(tDCS) and functional magnetic resonance imaging (fMRI) to investigate the effects of tDCS targeting antagonistic networks on brain dynamics. …”
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Alzheimer’s disease-specific transcriptomic and epigenomic changes in the tryptophan catabolic pathway by Kyonghwan Choe, Muhammad Ali, Roy Lardenoije, Renzo J.M. Riemens, Ehsan Pishva, Horst Bickel, Siegfried Weyerer, Per Hoffmann, Michael Pentzek, Steffi Riedel-Heller, Birgitt Wiese, Martin Scherer, Michael Wagner, Diego Mastroeni, Paul D. Coleman, Alfredo Ramirez, Inez H.G.B. Ramakers, Frans R.J. Verhey, Bart P.F. Rutten, Gunter Kenis, Daniel L.A. van den Hove

“…Molecular profiling, including assessing mRNA expression and DNA (hydroxy)methylation levels, was conducted using HumanHT-12 v4 Expression BeadChip and HM 450 K BeadChip arrays, respectively. Functional interactions between genes and identification of common phenotype-specific positive and negative elementary circuits were conducted using computational modeling, i.e. gene regulatory network (GRN) and network perturbational analysis. …”
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3D culturing as a promising strategy to enhance the angiogenic potential of adipose stem cell-derived secretome: insights into the role of miR-145-5p/ANGPT2 axis by G. Gerini, E. Mari, P. Pontecorvi, S. Camero, E. Romano, D. Ranieri, F. Megiorni, P. Fioramonti, A. Angeloni, C. Marchese, S. Ceccarelli

“…Recently, 3D culturing models has been shown to significantly influence the intrinsic characteristics of these cells, their gene expression and the secretome’s composition, thus affecting ASC paracrine effects and clinical potential. …”
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Crisis Communication About the Maui Wildfires on TikTok: Content Analysis of Engagement With Maui Wildfire–Related Posts Over 1 Year by Jim P Stimpson, Aditi Srivastava, Ketan Tamirisa, Joseph Keaweʻaimoku Kaholokula, Alexander N Ortega

“…Engagement metrics (likes and shares) were analyzed to assess public interaction with different themes. Multivariable linear regression models were used to examine the associations between log-transformed likes and shares and independent variables, including time intervals, video length, the inclusion of music or effects, content themes, and hashtags. …”
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Multidimensional bioinformatics analysis reveals the potential carcinogenic role of acrylamide in colorectal cancer by Xiaopeng Yu, Junjie Niu, Jinyang Hu

“…Validation across cohorts and experimental models is needed to confirm key targets and inform precision prevention. …”
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Combined Analysis of Transcriptome and Mendelian Randomization Reveals AKT1 and PPARG as Biomarkers Related to Glucose Metabolism in Sepsis by Ma J, Li W, Ma Q, Ding L, Wang Z, Wang R, Huang Y, Ma G, Gao J

“…Jie Ma,1,2,* Wendi Li,3 Qianqian Ma,1 Liying Ding,4 Zhaoyun Wang,1 Rong Wang,1 Yanan Huang,1 Gang Ma,2,* Jun Gao1,* 1Department of Anesthesia and Perioperative Medicine, First People’s Hospital of Yinchuan, The Second Clinical Medical College of Ningxia Medical University, Yinchuan, Ningxia, 750001, People’s Republic of China; 2Department of Anesthesia and Perioperative Medicine, General Hospital of Ningxia Medical University, The First Clinical Medical College of Ningxia Medical University, Yinchuan, Ningxia, 750004, People’s Republic of China; 3Department of Child Rehabilitation Education, Ningxia Rehabilitation Center for the Disabled, Yinchuan, Ningxia, 750002, People’s Republic of China; 4Department of Gynecology, Gynecology Clinic of Li Ying, Wuzhong, Ningxia, 751100, People’s Republic of China*These authors contributed equally to this workCorrespondence: Gang Ma, Department of Anesthesia and Perioperative Medicine, General Hospital of Ningxia Medical University, The First Clinical Medical College of Ningxia Medical University, Yinchuan, Ningxia, 750004, People’s Republic of China, Email magang2671@163.com Jun Gao, Department of Anesthesia and Perioperative Medicine, First People’s Hospital of Yinchuan, The Second Clinical Medical College of Ningxia Medical University, Yinchuan, Ningxia, 750001, People’s Republic of China, Email gaojun1605@sina.comIntroduction: This study aimed to identify diagnostic and therapeutic biomarkers related to glucose metabolism in sepsis, as hyperglycemia and blood glucose fluctuations influence sepsis progression.Methods: Datasets from public databases were analyzed using various methods, including differential expression analysis, PPI network screening, machine learning algorithms and Mendelian randomization. A nomogram model was developed, and biomarker functions were explored through enrichment analysis, immunoinfiltration analysis, transcription factors (TFs) and microRNA (miRNA) prediction, and drug prediction. …”
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ANATOMICAL AND GENETIC PREDISPOSITION FOR CARIES IN PERMANENT DENTITION. REVIEW by K.A. Udaltsova, E.O. Pisarenko

“…Childhood caries has strong heritability, with strongest effect in primary dentitions as revealed. Human models, including studies with twins, provide evidence that caries has a genetic component. …”
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Supply-Demand Matching Evaluation and Coupling Coordination of Cultural Ecosystem Services in Urban Park Green Spaces by Yang YU, Xian YANG, Xiang LI, Liyuan QIAN, Sixiang ZHOU

“…Second, the research applies a coupling coordination model to assess the coupling and coordination levels of CES supply and demand of urban park green spaces. …”
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Study on the Complexity Evolution of the Aviation Network in China by Shuolei Zhou, Cheng Li, Shiguo Deng

“…Unlike conventional studies focusing on isolated topological metrics, we introduce a triangulated methodology: ① a network sequence analysis capturing structural shifts in degree distribution, clustering coefficient, and path length; ② novel redundancy–entropy coupling quantifying complexity evolution beyond traditional efficiency metrics; and ③ economic-network coordination modeling with spatial autocorrelation validation. Key innovations reveal previously unrecognized dynamics: ① Time-embedded density matrices (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>ρ</mi></mrow></semantics></math></inline-formula>) demonstrate how sparsity balances information propagation efficiency (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>η</mi></mrow></semantics></math></inline-formula>) and response diversity, resolving the paradox of functional yet sparse connectivity. ② Redundancy–entropy synergy exposes adaptive trade-offs. …”
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Molecular mechanisms of the anchang group prescription in treating radiation enteritis: network pharmacology analysis and experimental evidence by Wei Liang, Bo Li, Yuehong Sun, Dapeng Jia, Tingting Hu, Rujing Huang, Zhilong Liu, Huan Yang, Baocai Chen, Xiaoming Yin, Xinying He, Yunchuan Sun

“…Functional enrichment analyses, including Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, were conducted via the DAVID database. …”
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The Effect of SLM Spreader Structures on the Powder Spreading Dynamics Mechanism of Diamond Tools by HUANG Guoqin, ZHANG Jiangtao, ZHU Xiaowei, XU Yangli, SUN Long, DU Yulong, ZHANG Yunhe

“…ObjectiveSelective laser melting (SLM)technology provides a new approach for the integratedmanufacture of metal-matrix diamond tools with structural and functional integration, which has drawn alot of interest from the academic and technicalcommunities. …”
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SERT-Deficient Mice Fed Western Diet Reveal Altered Metabolic and Pro-Inflammatory Responses of the Liver: A Link to Abnormal Behaviors by Raymond Cespuglio, Anna Gorlova, Konstantin Zabegalov, Kirill Chaprov, Evgeniy Svirin, Kseniia Sitdikova, Alisa Burova, Boris Shulgin, Ksenia Lebedeva, Alexei V. Deikin, Sergey Morozov, Tatyana Strekalova

“…This study presents the first evidence that altered liver functions are associated with pathological behaviors arising from genetic SERT deficiency.…”
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The Emergence of AI-Driven Virtual Hospitals: Redefining Patient Care Beyond Physical Boundaries by Ifrah Hameed, Hafiz Muhammad Haseeb Khaliq

“…Such individualized interactions make patient active in caring for their well-being. …”
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Protective effects of miR-24-2-5p in early stages of breast cancer bone metastasis by Margherita Puppo, Martine Croset, Davide Ceresa, Manoj Kumar Valluru, Victor Gabriel Canuas Landero, Monserrat Hernandez Guadarrama, Michele Iuliani, Francesco Pantano, Penelope Dawn Ottewell, Philippe Clézardin

“…Metastatic BC cells interact with bone cells, including osteoclasts and osteoblasts, creating a cancer niche where they seed and proliferate. …”
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Identifying the Dimensions and Components of Virtual Arabic Language Education in Iraq by Abbas Taher Allavi Gharabat, Nasrolah Ghashghaeizadeh, Jalal Shanta Jabir, Faranak mosavi

“…Theoretical Framework Virtual Education The term virtual education includes a wide range of applications and functions, including non-face-to-face education and electronic libraries (Abbasi Kasani, 2020). …”
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Childbearing and Family Instability: The Impact of Children on Women's Divorce Probability in Iran by Davoud Shahpari Sani, Mohammad Jalal Abbasi Shavazi

“…Conversely, alternative models, such as the role conflict model (Kaplan et al, 2020: 126-127; Twenge, 2003: 576), freedom restriction model (Garvin, 1997: 128), and financial cost model (Twenge, 2003: 576-578), posit that childbearing may contribute to marital dissolution by imposing additional burdens on couples. …”
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The Relationship Between Supply Environment, Supply Chain Integration and Performance Considering Opportunistic Behaviors by Abbas َAsadi, safanaz Heidari

“…Transaction costs also affect the way organizations interact with each other and cause organizations to show opportunistic behavior in order to maximize their profits. …”
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Re-use of Building Products in the Netherlands by Loriane Icibaci

“…The key findings in this segment were: Organizational The practice of reuse currently functions as an appendix of the demolition industry, bringing benefits as well as disadvantages. …”
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The Lived Experience of Women Regarding Family-Centric Roles in the Southern Neighbourhoods of Tehran by Fatemeh Farhadi babadi, Mehrdad Navabakhsh, Talieh Khademian

“…The study of family individualization in Iran with emphasis on the structural and functional changes trend of families (from 1957 to 2014). …”
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Protecting the Autonomy of Patients with Severe Mental Illness Through Psychiatric Advance Directive Peer-Facilitation by Nicholas Karasik

“…Shifting to a peer-support model would alleviate these constraints on providers, who could then focus on other aspects of patient care. …”
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