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  1. 641

    Nanodisc single-molecule pulldown to study lipid-protein interactions by Adriana Reyes-Ordoñez, Shweta Shree, Nilmani Singh, Stephen G. Sligar, Jie Chen

    Published 2025-07-01
    “…Beyond serving structural roles in the cell membrane, many phospholipids, including phosphatidylinositol phosphates (PIPs), are key signaling molecules that regulate a myriad of cellular processes. Specific interactions with PIPs are crucial for the functions of many signaling proteins, highlighting the need for a convenient and robust method to study lipid-protein interactions. …”
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    Urban modelling experiences for the representation of the historical city in Holy Land by Sandro Parrinello, Francesca Picchio, Raffaella De Marco

    Published 2018-12-01
    “…In particular, the paper will present the model of a portion of San Giovanni of Acre, relating to the area of Al-Jazzar Mosque, for the analysis of the historical stratification of religious and urban environments; a portion of Jerusalem adjacent to the monumental walls, for which it was built an interactive platform for the fruition in AR of the survey database; and a portion of the historical center of Bethlehem, for which an analysis of the characteristics of the ahwash quarters and buildings is addressed, useful for a semantic decomposition of the urban structure functional to the creation of an intelligent model for the monitoring of structural risk.…”
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  5. 645

    Pharmacokinetic analysis on compatibility of Atractylodes macrocephala and Paeoniae radix herb pair ameliorates functional constipation model rats using microdialysis with ultra‐pe... by Xiaoting Wang, Xiaojun Li, Rui Zhang, Yin Hong, Jiaqi Guan

    Published 2025-05-01
    “…Abstract Background In a previous study, we found that Atractylodes macrocephala and Paeoniae radix (AM‐PR) was useful for the alleviation of functional constipation (FC). However, the precise mechanism underlying the compatibility between AM and PR in the treatment of FC remains uncertain. …”
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  6. 646

    Toward a Blood Sensor for an IoT Monitoring: A New Approach for the Design and Implementation of Blood Light Absorption Systems Based on the Finite Element Method and the Diffusion... by Mouna Dhmiri, Yassine Manai, Tahar Ezzedine

    Published 2025-03-01
    “…The mesh generation process adapts to the target architecture using COMSOL Multiphysics for fluid–structure interaction (FSI) modeling. The fluence computing function solves the diffusion equation to model light intensity attenuation due to RBCs, and the SIL function compares computed results with real-time measurements, ensuring accuracy for potential real-time embedded system applications. …”
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  7. 647

    Modelling multi-pulse population dynamics from ultrafast spectroscopy. by Luuk J G W van Wilderen, Craig N Lincoln, Jasper J van Thor

    Published 2011-03-01
    “…In addition, the (selective) excitation (photoselection) and anisotropy of populations that interact with single or multiple intense polarised laser pulses is demonstrated as function of power density and beam profile. …”
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  10. 650

    Interaction effect of comorbid depression and proactive positivity coping strategy on the 1-year survival of patients with advanced cancer: a nationwide multicentre study in South... by Ju Youn Jung, Je-Yeon Yun, Jung Hun Kang, Su-Jin Koh, Yu Jung Kim, Seyoung Seo, Jung Hoon Kim, JaeKyung Cheon, Eun Joo Kang, Eun-Kee Song, Eun Mi Nam, Ho-Suk Oh, Hye Jin Choi, Jung Hye Kwon, Woo-Kyun Bae, Jung Eun Lee, Kyung Hae Jung, EunKyo Kang, Young Ho Yun

    Published 2025-06-01
    “…Coping strategies based on “proactive positivity” may facilitate adaptation to functional decline and limited life expectancy. However, few studies have examined the impact of the interaction between depressive symptoms and coping strategies on survival outcomes in this population. …”
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  11. 651

    Molecular Modelling and Prediction of the Physicochemical Properties of Polyols in Aqueous Solution by Fontenele Maria, Dumouilla Vincent, Boit Baptiste, Dussap Claude-Gilles

    Published 2025-01-01
    “…In addition to these analyses, the solubilities of sorbitol and mannitol in water as function of temperature using the COSMO-UCA model are estimated, providing a comprehensive view of polyol-water interactions.…”
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  12. 652

    Abnormal response to chronic social defeat stress and fear extinction in a mouse model of Lynx2-based cholinergic dysregulation by Kristin R. Anderson, Peter J. Rogu, Talulla B. Palumbo, Julie M. Miwa

    Published 2025-04-01
    “…Mice null for Lynx2/Lypd1 (Lynx2 KO) show elevated basal anxiety-like behavior in tests such as elevated plus maze, light-dark box and social interaction assays. Here, we queried how a line predisposed to basal anxiety-like behavior would respond to specific stressors, using validated models of experiential-based affective disorders such as fear extinction, acute and chronic social defeat stress assays. …”
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  13. 653

    Interaction of vibroimpact lattice and screen sieve in anti-phase oscillation mode by V. S. Sizikov, S. A. Sizikov

    Published 2022-11-01
    “…Such construction provides increasing the effectiveness of sieve cleaning due to the transfer to sieve impact impulse in each screen oscillation period and reducing its excessive damage and abrasion by increasing the area of vibroimpact lattice and sieve interaction. The purpose of the work is to determinate functional relationships of dynamical interaction between elements of three-mass vibroimpact ‘screen body – vibroimpact lattice – sieve’ system for providing the necessary value of impact impulse transferred to sieve in relation to screen body oscillation frequency and amount of gap between lattice and sieve.Materials and methods. …”
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  14. 654

    Advanced Multiscale Modeling of Potassium‐Ion Batteries for Interplay of Electrochemical and Mechanical Behavior Across Scales by Subeen Kim, Yun Kim, Yoon Koo Lee, Jihwan Song

    Published 2025-07-01
    “…In this work, a comprehensive multiscale modeling approach is introduced to analyze both the electrochemical and mechanical behavior of potassium‐ion batteries, integrating diffusion coefficient and mechanical properties derived from density functional theory calculations with the 3D particle network model. …”
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    Mathematical and Numerical Modelling of Interference of Immune Cells in the Tumour Environment by Sweta Sinha, Paramjeet Singh, Mehmet Emir Koksal

    Published 2023-01-01
    “…In this article, the behaviour of tumour growth and its interaction with the immune system have been studied using a mathematical model in the form of partial differential equations. …”
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  17. 657

    System Elements Identification Method for Heat Transfer Modelling in MBSE by Patrick Jagla, Georg Jacobs, Vincent Derpa, Lukas Irnich, Gregor Höpfner, Stefan Wischmann, Joerg Berroth

    Published 2025-04-01
    “…It is shown that a small set of recurring system elements can be used to represent a large number of individual thermal interactions, within TMS components and, therefore, streamline modelling efficiency significantly.…”
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  18. 658

    Unraveling mitotic protein networks by 3D multiplexed epitope drug screening by Lorenz J Maier, Stefan M Kallenberger, Katharina Jechow, Marcel Waschow, Roland Eils, Christian Conrad

    Published 2018-08-01
    “…Our approach reveals novel insights into spindle fragility and chromatin stress, and predicts unknown interactions between proteins in specific mitotic pathways. 3D SPECS's ability to map potential drug targets by multiplexed immunofluorescence in 3D cell culture combined with our automated high‐content assay will inspire future functional protein expression and drug assays.…”
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    Efficient Bayesian inference for mechanistic modelling with high-throughput data. by Simon Martina Perez, Heba Sailem, Ruth E Baker

    Published 2022-06-01
    “…By applying a detailed mathematical model of single cell motility, proliferation and death to a data set of 118 gene knockdowns, we characterise functional subgroups of gene knockdowns, each displaying its own typical combination of local cell density-dependent and -independent motility and proliferation patterns. …”
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