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641
Nanodisc single-molecule pulldown to study lipid-protein interactions
Published 2025-07-01“…Beyond serving structural roles in the cell membrane, many phospholipids, including phosphatidylinositol phosphates (PIPs), are key signaling molecules that regulate a myriad of cellular processes. Specific interactions with PIPs are crucial for the functions of many signaling proteins, highlighting the need for a convenient and robust method to study lipid-protein interactions. …”
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643
Behavioral variant frontotemporal dementia as a model for understanding the cognitive and cerebral determinants of verbal creativity
Published 2025-08-01“…Current models highlight the interaction between associative and executive processes underpinned by the default mode (DMN), executive control (ECN) and salience networks (SN). …”
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644
Urban modelling experiences for the representation of the historical city in Holy Land
Published 2018-12-01“…In particular, the paper will present the model of a portion of San Giovanni of Acre, relating to the area of Al-Jazzar Mosque, for the analysis of the historical stratification of religious and urban environments; a portion of Jerusalem adjacent to the monumental walls, for which it was built an interactive platform for the fruition in AR of the survey database; and a portion of the historical center of Bethlehem, for which an analysis of the characteristics of the ahwash quarters and buildings is addressed, useful for a semantic decomposition of the urban structure functional to the creation of an intelligent model for the monitoring of structural risk.…”
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645
Pharmacokinetic analysis on compatibility of Atractylodes macrocephala and Paeoniae radix herb pair ameliorates functional constipation model rats using microdialysis with ultra‐pe...
Published 2025-05-01“…Abstract Background In a previous study, we found that Atractylodes macrocephala and Paeoniae radix (AM‐PR) was useful for the alleviation of functional constipation (FC). However, the precise mechanism underlying the compatibility between AM and PR in the treatment of FC remains uncertain. …”
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646
Toward a Blood Sensor for an IoT Monitoring: A New Approach for the Design and Implementation of Blood Light Absorption Systems Based on the Finite Element Method and the Diffusion...
Published 2025-03-01“…The mesh generation process adapts to the target architecture using COMSOL Multiphysics for fluid–structure interaction (FSI) modeling. The fluence computing function solves the diffusion equation to model light intensity attenuation due to RBCs, and the SIL function compares computed results with real-time measurements, ensuring accuracy for potential real-time embedded system applications. …”
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647
Modelling multi-pulse population dynamics from ultrafast spectroscopy.
Published 2011-03-01“…In addition, the (selective) excitation (photoselection) and anisotropy of populations that interact with single or multiple intense polarised laser pulses is demonstrated as function of power density and beam profile. …”
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Amorphization and siliconization of silicon carbide as a first wall material
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650
Interaction effect of comorbid depression and proactive positivity coping strategy on the 1-year survival of patients with advanced cancer: a nationwide multicentre study in South...
Published 2025-06-01“…Coping strategies based on “proactive positivity” may facilitate adaptation to functional decline and limited life expectancy. However, few studies have examined the impact of the interaction between depressive symptoms and coping strategies on survival outcomes in this population. …”
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651
Molecular Modelling and Prediction of the Physicochemical Properties of Polyols in Aqueous Solution
Published 2025-01-01“…In addition to these analyses, the solubilities of sorbitol and mannitol in water as function of temperature using the COSMO-UCA model are estimated, providing a comprehensive view of polyol-water interactions.…”
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652
Abnormal response to chronic social defeat stress and fear extinction in a mouse model of Lynx2-based cholinergic dysregulation
Published 2025-04-01“…Mice null for Lynx2/Lypd1 (Lynx2 KO) show elevated basal anxiety-like behavior in tests such as elevated plus maze, light-dark box and social interaction assays. Here, we queried how a line predisposed to basal anxiety-like behavior would respond to specific stressors, using validated models of experiential-based affective disorders such as fear extinction, acute and chronic social defeat stress assays. …”
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653
Interaction of vibroimpact lattice and screen sieve in anti-phase oscillation mode
Published 2022-11-01“…Such construction provides increasing the effectiveness of sieve cleaning due to the transfer to sieve impact impulse in each screen oscillation period and reducing its excessive damage and abrasion by increasing the area of vibroimpact lattice and sieve interaction. The purpose of the work is to determinate functional relationships of dynamical interaction between elements of three-mass vibroimpact ‘screen body – vibroimpact lattice – sieve’ system for providing the necessary value of impact impulse transferred to sieve in relation to screen body oscillation frequency and amount of gap between lattice and sieve.Materials and methods. …”
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654
Advanced Multiscale Modeling of Potassium‐Ion Batteries for Interplay of Electrochemical and Mechanical Behavior Across Scales
Published 2025-07-01“…In this work, a comprehensive multiscale modeling approach is introduced to analyze both the electrochemical and mechanical behavior of potassium‐ion batteries, integrating diffusion coefficient and mechanical properties derived from density functional theory calculations with the 3D particle network model. …”
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655
Laser cladded Ni60WC coatings: Structure evolution, atomic model and electrochemical corrosion
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656
Mathematical and Numerical Modelling of Interference of Immune Cells in the Tumour Environment
Published 2023-01-01“…In this article, the behaviour of tumour growth and its interaction with the immune system have been studied using a mathematical model in the form of partial differential equations. …”
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657
System Elements Identification Method for Heat Transfer Modelling in MBSE
Published 2025-04-01“…It is shown that a small set of recurring system elements can be used to represent a large number of individual thermal interactions, within TMS components and, therefore, streamline modelling efficiency significantly.…”
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658
Unraveling mitotic protein networks by 3D multiplexed epitope drug screening
Published 2018-08-01“…Our approach reveals novel insights into spindle fragility and chromatin stress, and predicts unknown interactions between proteins in specific mitotic pathways. 3D SPECS's ability to map potential drug targets by multiplexed immunofluorescence in 3D cell culture combined with our automated high‐content assay will inspire future functional protein expression and drug assays.…”
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659
Voronoi diagrams and Delaunay triangulation for modelling animal territorial behaviour
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660
Efficient Bayesian inference for mechanistic modelling with high-throughput data.
Published 2022-06-01“…By applying a detailed mathematical model of single cell motility, proliferation and death to a data set of 118 gene knockdowns, we characterise functional subgroups of gene knockdowns, each displaying its own typical combination of local cell density-dependent and -independent motility and proliferation patterns. …”
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