Identification and validation of three diagnostic autophagy-related genes associated with advanced plaques and immune cell infiltration in carotid atherosclerosis based on integrat... by Tiegen Huang, Chen Su, Quanli Su, Yali Nie, Zhenni Xiao, Yao Tang, Jiahao Wang, Xiaotian Luo, Yixin Tang

“…Hematoxylin and eosin (HE) staining was used to estimate the plaque histology in the AS mouse model. Western blotting, quantitative real-time PCR (qRT-PCR), and immunohistochemistry (IHC) were performed to validate the protein and mRNA expression levels of the key CAS-related DE-ATGs in the in vitro and in vivo models. …”
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Inhibition of the FEN1-PBX1 axis elicits cellular senescence in breast cancer via the increased intracellular reactive oxygen species levels by Min Wu, Benmeng Wu, Xiaoshan Huang, Zirui Wang, Miaolin Zhu, Yaqin Zhu, Lin Yu, Jingjing Liu

“…A xenograft mouse model was employed to validate the effect of FEN1 on breast cancer cell senescence and apoptosis. …”
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Sesbania grandiflora activated carbon as a high-efficiency stable and reusable adsorbent for sustainable fluoride removal by D. Sivakumar, M. Perarul Selvan, J. Nouri, M. Juhi Jabin, S. Priyanka, G. Madhubala

“…Adsorption isotherms and kinetics were analyzed using Freundlich and Langmuir models, while reusability was evaluated over five regeneration cycles with 0.1 mole sodium hydroxide.RESULTS: Fourier transform infrared spectroscopy revealed interactions between fluoride ions and surface functional groups. …”
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<i>Ab initio</i> Calculations of the Electronic-Energy Structure and Optical Properties of Lanthanum and Neodymium Pyrozirconates by A. A. Lavrentyev, B. V. Gabrelian, Vu Van Tuan, K. F. Kalmykova

“…Based on model calculations within the framework of the density functional theory, the electron-energy structure of pyrozirconates La2Zr2O7 and Nd2Zr2O7, containing Zr and having the crystal structure of pyrochlore was investigated. …”
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Investigation Into the Pathogenesis of Type 2 Cardiorenal Syndrome via the ROS–TRPM2 Signaling Axis by Yanxia Li, Fengrong Wang

“…Thus, this study aimed to explore the biological functions and mechanisms of the ROS–TRPM2 signaling axis in type 2 CRS. …”
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Review and Comparative Evaluation of Mobile Apps for Cardiovascular Risk Estimation: Usability Evaluation Using mHealth App Usability Questionnaire by Adrijana Svenšek, Lucija Gosak, Mateja Lorber, Gregor Štiglic, Nino Fijačko

“…Based on the apps’ characteristics (ie, developed for health care professionals or patient use) and their functions (single or multiple CVD risk calculators), we conducted a descriptive analysis. …”
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Exploring the mechanism of platycodin D in inhibiting nasopharyngeal carcinoma based on network pharmacology combined with experimental validation by LEI Benlan, YANG Jiangping, CHEN Yanfang, HUANG Jinglun, ZHANG Xiping, MA Canfang, LIANG Gang, JIAO Aijun

“…The protein-protein interaction (PPI) network of the intersection targets and the"platycodin D-target-nasopharyngeal carcinoma-pathway" network model were obtained using the STRING database and Cytoscape software. …”
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MiR-485-3p/MELK cascade mediates tumor progression in pancreatic cancer by Yishan Huang, Ting Yang, Chen Yang, Bo Tang, Bo Su, Xiaojun Yang

“…The identification of differentially expressed genes (DEGs) and subsequent analyses, including signaling pathway enrichment, functional classification, and protein-protein interaction (PPI) network construction, were conducted using three public datasets: GSE32676, GSE71989, and GSE16515. …”
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Study of the psychometric properties of the HLS-EU-12 questionnaire in rural Bangladesh. by Fakir M Amirul Islam

“…Initial examination indicated that the tool had a poor overall fit with the Rasch model, shown by a significant item-trait interaction (χ2 = 100.5 df = 48, p < 0.001). …”
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Clarification and Prioritization of Omnichannel Marketing Antecedents: A Meta-Synthesis Approach by Hamid Reza Irani, Elham Ebrahimi, Babak Somi

“…ConclusionAccording to the study's findings, the implementation of omnichannel marketing relies on four key concepts, which are processes and functions, environment, customer interaction, as well as resources and capital. …”
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Decoding per- and polyfluoroalkyl substances (PFAS) in hepatocellular carcinoma: a multi-omics and computational toxicology approach by Yanggang Hong, Deqi Wang, Zeyu Liu, Yuxin Chen, Yi Wang, Jiajun Li

“…We constructed a protein–protein interaction (PPI) network and a survival risk model, the PFAS-related HCC signature (PFASRHSig), based on integrated machine learning to identify prognostic biomarkers, with the goal of identifying core targets of PFAS in HCC progression and prognosis. …”
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Measuring attitudes towards ethnic minority patients: the revalidated REMP-3 instrument for graduate healthcare practitioners by Stijn Schelfhout, Robin Vandecasteele, Sara Willems, Eva Derous, Stéphanie De Maesschalck

“…We used structural equation modeling to model the framework of intercultural effectiveness on two waves of independent data, N 2021 = 368 and N 2022 = 390. …”
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Role of lysine acetylation-related genes in the diagnosis and prognosis of glioma by Min Zhou, Bing Wang, Richu Liang, Xinping Luan

“…Subsequently, enrichment analysis and protein–protein interaction (PPI) network was processed. Then, prognosis genes were selected, risk model was constructed and verified. …”
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Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South... by Angelique Hölzemer, Christina F Thobakgale, Camilo A Jimenez Cruz, Wilfredo F Garcia-Beltran, Jonathan M Carlson, Nienke H van Teijlingen, Jaclyn K Mann, Manjeetha Jaggernath, Seung-gu Kang, Christian Körner, Amy W Chung, Jamie L Schafer, David T Evans, Galit Alter, Bruce D Walker, Philip J Goulder, Mary Carrington, Pia Hartmann, Thomas Pertel, Ruhong Zhou, Thumbi Ndung'u, Marcus Altfeld

“…Better understanding of the mechanisms by which HIV-1 evades NK-cell-mediated immune pressure and the functional validation of a structural modeling approach will facilitate the development of novel targeted immune interventions to harness the antiviral activities of NK cells.…”
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<i>Heortia vitessoides</i> Infests <i>Aquilaria sinensis</i>: A Systematic Review of Climate Drivers, Management Strategies, and Molecular Mechanisms by Zongyu Yin, Yingying Chen, Huanrong Xue, Xiaofei Li, Baocai Li, Jiaming Liang, Yongjin Zhu, Keyu Long, Jinming Yang, Jiao Pang, Kaixiang Li, Shaoming Ye

“…Current research has preliminarily revealed its biological traits and gene functions. However, significant gaps persist in integrating climate adaptation mechanisms, control technologies, and host interaction networks across disciplines. …”
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Single-cell and spatial atlas of glioblastoma heterogeneity: characterizing the PCLAF+ subtype and YEATS4’s oncogenic role by Siqi Ma, Yuwei Sun, Shaowei Zheng, Yilong Fu, Liangyu Wang, Dun Liu, Henan Jiao, Xuqiang Zhu, Xueyuan Li, Dongming Yan, Di Chen, Zi Ye

“…Furthermore, the C2 PCLAF+ subtype established a specific interaction with fibroblasts through the MDK-LRP1 ligand–receptor pair. …”
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Research on the Synergistic Mechanism of Maize–Soybean Rotation and Bio-Organic Fertiliser in Cold Regions by Zijian Wang, Hao Tian, Nan Sun, Haocheng Wang, Songyan Tang, Shengjie Chen, Xuebing Wang, Shiwei Ren, Xiangyuan Zuo, Xingbo Zhao

“…Bio-organic fertilisers combine the benefits of organic fertiliser substrates with those of functional microorganisms. Correlation, cluster, and interaction analyses revealed that the synergistic mechanisms between maize–soybean rotation and bio-organic fertilisers in cold regions are primarily reflected in improved soil quality, enhanced nutrient cycling efficiency, increased nitrogen fixation in soybean root nodules, stimulated microbial activity, and greater resilience to environmental stress. …”
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SOCIAL COMPETENCE FORMATION AMONG TEENAGERS FROM HUMANIST TREND MULTIPLE-AGED GROUPS by Larisa A. Krapivina

“…The author describes objective conditions for the uprise of extremist, subcultural youth of multiple-aged groups, and the reasons whence they begin to perform distinctive functions that are specific for teenagers. Options for models of MAG humanistic educational systems formed in Russian and foreign social and pedagogical practice are listed. …”
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Control of Clostridioides difficile virulence and physiology by the flagellin homeostasis checkpoint FliC-FliW-CsrA in the absence of motility by Duolong Zhu, Katherine J. Wozniak, Firas Midani, Shaohui Wang, Xingmin Sun, Robert A. Britton

“…ABSTRACT Mutations affecting Clostridioides difficile flagellin (FliC) have been shown to be hypervirulent in animal models and display increased toxin production and alterations in central metabolism. …”
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Circ_HUWE1: a novel regulator of lipid accumulation, inflammation, and gut microbiota in atherosclerosis by Zulong Sheng, Yi Fan, Zhenjun Ji, Yanru He, Rui Zhang, Yuyu Yao, Genshan Ma

“…Methods Circ_HUWE1 expression was evaluated in coronary artery disease (CAD) patients and in fecal samples from AS patients. An ApoE−/− mouse model of high-fat diet (HFD)-induced atherosclerosis was employed to assess functional role of circ_HUWE1. …”
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