Features of the Development Strategy Customer Relationship Management by I. M. Gurova

“…Functional, strategic and economic analysis, methods of formalization, forecasting and expert assessments are used to generalize information and solve assigned tasks. …”
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Marek's disease virus-1 unique gene LORF1 is involved in viral replication and MDV-1/Md5-induced atrophy of the bursa of Fabricius. by Chenyi Bao, Jun Chu, Qi Gao, Shasha Yang, Xiaoyu Gao, Wenwen Chen, Fuchun Yang, Fei Jiang, Chenxi Tong, Mingyi Lei, Linlin Jiao, Jitong Li, Kexin Wei, Xue Lian, Kai Li, Suresh Kumar Tikoo, Nikolaus Osterrieder, Lorne A Babiuk, Yufeng Li, Yong-Sam Jung, Yingjuan Qian

“…Importantly, it also serves as a comparative model for studying herpesvirus-induced tumor formation in humans. …”
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Molecularly imprinted biomimetic plasmonic sensor decorated with gold nanoparticles for selective and sensitive detection of bisphenol A by Ilgım Göktürk, Süleyman Aşır, Deniz Türkmen, Adil Denizli, Fatma Yılmaz

“…Molecularly imprinted polymers inspired by antigen-antibody interactions have received substantial interest as a biomimetic artificial receptor system in environmental applications. …”
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Role of community health workers in type 2 diabetes mellitus self-management: A scoping review. by Bonaventure Amandi Egbujie, Peter Arthur Delobelle, Naomi Levitt, Thandi Puoane, David Sanders, Brian van Wyk

“…Support services included informational, emotional, appraisal and instrumental support. Models of CHW care included facility linked nurse-led CHW coordination, facility-linked CHW led coordination and standalone CHW interventions without facility interaction.…”
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Investigating the impact of process parameters on the thermomechanical properties of three-dimensional (3D) printed polymer-nanoclay composites by Sheymaa Alazzawi, Noor Hassan Ali, Suha K. Shihab, Muammel M. Hanon

“…The results of this work mark a great milestone in the field given the great potential of using environmentally friendly, plant-based composite systems in high-performance applications such as functional prototypes, medical models, and complex industrial components. …”
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Leading Factors of Progression in Patients with Cardiac Amyloidosis by A. S. Rameeva, V. V. Rameev, I. N. Bobkova, A. F. Safarova, Zh. D. Kobalava, S. V. Moiseev

“…In the special investigation group (n=58) of AL (n=55) and ATTR (n=3) amyloidotic cardiopathy patients there were evaluated prognostically important structural and functional changes in myocardium with standard and impulse-wave tissue dopplerometric echocardiography in comparison with NTproBNP serum levels.Results. …”
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Effects of Mind-Body Qigong Exercise on Overall Health, Fatigue/Sleep, and Cognition in Older Chinese Immigrants in the US: An Intervention Study with Control by Jianghong Liu, Yi Yang, Clara Li, Adriana Perez, Adrian Raine, Haoer Shi, Liye Zou

“…Repeated measures general linear model (GLM) and paired samples t-tests were used for data analyses. …”
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Aptamer‑mediated modulation of eEF1 enhances salt stress tolerance in rice by Yongxiang Huang, Haomin Chen, Zhihao Xie, Daming Chen, Mingming Chen

“…Functionally, rice seedlings transfected with S2-A aptamer under 150 mM NaCl stress exhibited improved growth, enhanced chlorophyll content, reduced lipid peroxidation, and a coordinated upregulation of key salt stress-responsive genes (OsSOS1, OsHKT1, OsDREB2A). …”
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Identification and validation of ANXA3 and SOCS3 as biomarkers for acute myocardial infarction related to sphingolipid metabolism by Ling Sun, Lingyan He, Hai-Hua Pan, Chang-Lin Zhai

“…Single-cell RNA sequencing (scRNA-seq) identified key cell types and their functions. Biomarkers were validated via reverse transcription quantitative polymerase chain reaction (RT-qPCR). …”
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Ailanthone blocks mitophagy to promote mtDNA leakage through BAX-BAK1 pores and suppress hepatocellular carcinoma cell proliferation by Yan Qin, Ying Gao, Dan Wu, Qing-Qing Liu, Chang Su, Guan Liu, Le Yang, Ming-Gao Zhao, Jing-Yue Yao

“…WB and IHC experiments were applied to detect protein expression. Protein-protein interactions detected by immunoprecipitation and immunofluorescence imaging. …”
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Polyvinyl alcohol film comprising biochar modified titanium dioxide nanocomposites as decoloring and disinfectant agents by Ahmed F. Ghanem, Abdelrahman A. Badawy, Ahmed A. Youssef, Naema S. Yehia, Farag A. Issa, Manal A. Nofal

“…FTIR showed strong interactions between the surface functional groups of the obtained nanomaterials. …”
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Berberine in the treatment of radiation-induced skin injury: insights from proteomics and network pharmacology by Jie Zou, Jie Zou, Xia-Juan Xiao, Ping Zhang, Xing-Zi Huang, Jing Wang, Chun-Qin Tao, Xiao-Lan Ou, Gong Chen, Ting-Hao He, Long Yang, Biao Huang, Dao-Jiang Yu, Dao-Jiang Yu, Yu Zhao

“…Molecular functions and pathways were analyzed through GO and KEGG pathway enrichment analyses. …”
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Microbiota-derived IPA alleviates intestinal mucosal inflammation through upregulating Th1/Th17 cell apoptosis in inflammatory bowel disease by Han Gao, Mingming Sun, Ai Li, Qiaoyan Gu, Dengfeng Kang, Zhongsheng Feng, Xiaoyu Li, Xuehong Wang, Liang Chen, Hong Yang, Yingzi Cong, Zhanju Liu

“…The gut microbiota-derived metabolite indole-3-propionic acid (IPA) plays an important role in maintaining intestinal mucosal homeostasis, while the molecular mechanisms underlying IPA regulation on mucosal CD4+ T cell functions in inflammatory bowel disease (IBD) remain elusive. …”
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COMMD3 Regulates Copper Metabolism via the ATOX1-ATP7A-LOX Axis to Promote Multiple Myeloma Progression by Yajun Wang, Bo Zhang, Fengjuan Fan, Fei Zhao, Jian Xu, Yuhuan Zheng, Chunyan Sun, Yu Hu

“…RNA sequencing was conducted on COMMD3 knockdown cells to identify differentially expressed genes. Functional assays measured cell proliferation, migration, apoptosis, and copper metabolism, with a non-obese diabetic severe combined immune-deficiency gamma (NSG) mouse xenograft model providing in vivo validation. …”
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The minor allele rs2295613(A), protective against systemic lupus erythematosus, makes a differential contribution to the activity of the <i>SLAMF1</i> gene promoter in T helpers an... by A. N. Uvarova, L. V. Putlyaeva, E. A. Zheremyan, E. M. Stasevich, M. M. Murashko, E. A. Bogomolova, K. V. Korneev, D. E. Demin, A. M. Schwartz, D. V. Kuprash

“…In the present work, we performed a functional analysis of single nucleotide promoter polymorphisms rs2295614(A&gt;T) and rs2295613(G&gt;A) of the SLAMF1 gene in the models of T-regulatory lymphocytes (MT-2 cell line) and T helpers (Jurkat cell line). …”
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Eimeria tenella aspartyl protease is identified as a potential TLR15 ligand and activates macrophages and dendritic cells in chickens by Chen Chen, Zhichao Men, Xianglin Pu, Mingmin Lu, Lixin Xu, Ruofeng Yan, Xiangrui Li, Xiaokai Song

“…However, the avian-specific TLR15 has unclear immunological functions, including its specific ligands and role in anti-coccidia immunity. …”
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Experimental Evaluation and Thermodynamic Analysis of Magnetic Fe₃O₄@La-Zr-MOFs for Highly Efficient Fluoride and Phosphate Removal by Ziyi Zhang, Xinyun Chen, Yongyi Yu, Wenbin Pan, Ruilai Liu, Jiangyan Song, Jiapeng Hu

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Environmentally Friendly Synthesis of New Mono- and Bis-Pyrazole Derivatives; In Vitro Antimicrobial, Antifungal, and Antioxidant Activity; and In Silico Studies: DFT, ADMETox, and... by Oussama Merzouki, Nadia Arrousse, Elhachmia Ech-chihbi, Ashwag S. Alanazi, El Houssine Mabrouk, Mohamed Hefnawy, Abdelfattah El Moussaoui, Hanane Touijer, Azeddin El Barnossi, Mustapha Taleb

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Genome editing of TXNIP in human pluripotent stem cells for the generation of hepatocyte-like cells and insulin-producing islet-like aggregates by Leonardo Traini, Javier Negueruela, Bernat Elvira, Wadsen St-Pierre-Wijckmans, Valerie Vandenbempt, Carlos E. Buss, Ao Li, Israel Pérez-Chávez, Francisco Ribeiro-Costa, Mariana Nunes, Joris Messens, Daria Ezeriņa, David C. Hay, Mayank Bansal, Esteban N. Gurzov

“…Conclusions Our study demonstrates that TXNIP deficiency does not improve the differentiation or functionality of HLCs and SC-islets. We present the generation and characterisation of TXNIP −/− and TXNIP +/+ H1-hESCs, HLCs, and SC-islets as valuable models for future studies on the role of TXNIP in metabolic cell biology.…”
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Unique target binding by the C-terminal region of FHR1 provides a new perception of aHUS pathology by Luce Perie, Selina Stippa, Christoph Saffer, Christoph Saffer, Andrea Hartmann, Mathias Mörgelin, Svante L. H. Zipfel, Marc Thilo Figge, Marc Thilo Figge, Thorsten Wiech, Christine Skerka, Peter F. Zipfel, Peter F. Zipfel

“…The action profiles of FHR1 and Factor H were calculated and compared.ResultsFunctional data revealed that residues YVQ vs HLE in SCR3 and LA vs SV in SCR5 altered ligand binding and surface interaction, influenced target recognition and complement control. …”
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