Suggested Topics within your search.
Suggested Topics within your search.
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6421
Engineered small extracellular vesicles for targeted delivery of perlecan to stabilise the blood–spinal cord barrier after spinal cord injury
Published 2025-06-01“…Perlecan is a crucial component of basement membranes, playing a vital role in stabilising BSCB homeostasis and functions through its interactions with other matrix components, growth factors, and receptors. …”
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6422
Cyber-Physical Systems Enabled Transport Networks in Smart Cities: Challenges and Enabling Technologies of the New Mobility Era
Published 2022-01-01“…The development of urban structures, functionality, and prosperity are intricately connected to how the city designs its mobility infrastructure. …”
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6423
Nonmuscle Myosin-2B Regulates Apical Cortical Mechanics, ZO-1 Dynamics and Cell Size in MDCK Epithelial Cells
Published 2025-07-01“…These results extend our understanding of the functions of NM2B by describing its role in the regulation of the mechanical properties of the apical membrane cortex and cell size and validate our model about the role of cingulin–NM2B interaction in the regulation of ZO-1 dynamics.…”
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6424
Association between multimorbidity and capacity impairment in the adult population of Chile: findings of the National Health Survey 2016–2017
Published 2025-07-01“…For capacity impairment, the survey included 24 items in eight dimensions that represent functioning as a reflection of the overall health experience perceived by an individual with a health condition and interacting with the environment.Results The 2016–2017 ENS (Encuesta Nacional de Salud) included 6233 participants (mean age 48.9±19.3, and 62% women). …”
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6425
Contemporary Coping Patterns Among Violence-Impacted Adolescent Black Males: An Interpretive Descriptive Study
Published 2025-04-01“…Integrating the Phenomenological Variant of Ecological Systems Theory (PVEST) and the Transactional Model of Stress and Coping (TMSC), we examined how structural and interpersonal factors shape YBM agency and coping responses. …”
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6426
Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold
Published 2023-12-01“…Finally, we used AlphaFold models of non-human LAMP-1 to understand the lack of mAb cross-reactivity. …”
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6427
A Lightweight Transformer-Based Spatiotemporal Analysis Prediction Algorithm for High-Dimensional Meteorological Data
Published 2024-12-01“…SA-Fit shortens training time and significantly reduces model parameters while using the Transformer structure to ensure prediction accuracy.…”
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6428
Sustainable optimization of high specific surface area Spartina alterniflora biochar for Rhodamine B removal and mechanism
Published 2025-07-01“…Microscopic analysis validated the presence of an appealing porous structure and surface functionalities that are key for the adsorption of RhB. …”
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6429
Galectin-9: diverse roles in skin disease
Published 2025-07-01“…Galectin-9 mediates its physiological functions through interactions with multiple membrane receptors, including T-cell immunoglobulin mucin-domain containing-3 (Tim-3), immunoglobulin E, and the hyaluronan receptor CD44. …”
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6430
Acaricide Resistance Monitoring and Structural Insights for Precision <i>Tetranychus urticae</i> Management
Published 2025-04-01“…Structural analysis revealed key interactions between acaricides and target proteins in both wild-type and mutant variants, providing novel insights into the functional impacts of these mutations. …”
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6431
Innovative optical imaging strategies for monitoring immunotherapy in the tumor microenvironments
Published 2024-10-01“…Technologies like FLI and BLI are pivotal in tracking immune responses in preclinical models, while PAI provides functional imaging with deeper tissue penetration. …”
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6432
IL-17 A expression negatively correlates with γδ T-Cell density in human psoriasis lesions: a novel implication for disease pathogenesis
Published 2025-07-01“…Abstract Background Psoriasis, an inflammatory autoimmune disease, arises from intricate interactions between the immune system and epithelium. …”
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6433
Investigating adhesion mechanisms in warm-mix recycled asphalt: a multiscale atomic force microscopy and molecular dynamics approach
Published 2025-07-01“…AFM and MD have a good univariate linear functional relationship, the decidability coefficient R2 > 0.9. …”
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6434
Identifying disease progression biomarkers in metabolic associated steatotic liver disease (MASLD) through weighted gene co-expression network analysis and machine learning
Published 2025-04-01“…Additionally, Protein-Protein Interaction (PPI) networks, functional enrichment, and immune infiltration analyses were performed. …”
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6435
BMP6, a potential biomarker of inflammatory fibrosis and promising protective factor for dilated cardiomyopathy
Published 2025-01-01“…Conclusion BMP6 emerges as a promising biomarker for DCM, and its functional role in exerting an antifibrotic effect underscores its potential as a therapeutic target.…”
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6436
Factors influencing the combined performance of hot-rolled bimetallic composite plates prepared via hot compression
Published 2018-04-01“…The hot-compression process of the 316L/Q345R system was simulated on its atom structure model. The potential functions of the embedded-atom method were employed to describe the interaction between Fe, Cr, and Ni. …”
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6437
High-Performance Identification and Control of MIMO (Multiple Input—Multiple Output) Experimental Module with Fractional-Order Approach Application
Published 2025-04-01“…Moreover, comparisons with integer order models and controllers (IOPID-IMC) were performed. …”
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6438
Trigger thresholds and propagation mechanism of meteorological drought to agricultural drought in an inland river basin
Published 2025-04-01“…In this study, based on Copula functions, we quantified the thresholds and process of meteorological drought to agricultural drought in an alpine-oasis-desert inland river basin of China for the period of 1980–2020. …”
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6439
Exploration of the mechanism of 5-Methylcytosine promoting the progression of hepatocellular carcinoma
Published 2025-02-01“…5-Methylcytosine (m5C) is a ubiquitous RNA modification that is closely related to various cellular functions. However, no studies have comprehensively demonstrated the role of m5C in hepatocellular carcinoma (HCC) progression. …”
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6440
Synthesis of Zn/Al layered double hydroxides magnetic-nanoparticle for removal of humic acid
Published 2024-01-01“…A novel adsorbent of Zn/Al-LDH functionalized magnetic composite nanomaterial was successfully synthesis using a hydrothermal co-precipitation approach with NaOH as precipitating agent, and applied for the removal of humic acid (HA) from aqueous solution. …”
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