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6301
Vapor Phase Installation of CpCo(CO)2 in MOF‐808
Published 2025-07-01“…The mechanism of cobalt installation in MOF‐808 through atomic layer deposition (ALD) upon CpCo(CO)2 exposure is investigated through in situ FTIR spectroscopy complemented by density functional theory modeling. The role of subsequent H2O exposure in the hydrolysis of carbonyl and cyclopentadienyl ligands to complete the installation is also investigated. …”
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6302
miRNA-29b-1-5p mediates an antiviral activity by targeting the HBV entry receptor in human hepatocytes
Published 2025-07-01“…Functional analysis indicated that miR-29b-1-5p directly targeted the NTCP 3ʹ-UTR, leading to significant inhibition of NTCP transcripts. …”
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6303
Sequential pretreatment with hydroxyl radical and manganese peroxidase for the efficient enzymatic saccharification of corn stover
Published 2024-11-01“…Subsequently, in vitro functional studies found that ⋅OH possessed the ability to disrupt the smooth surface structure of corn stover, resulting in increased enzymatic saccharification and cellulose accessibility. …”
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6304
Glucofuranose as corrosion inhibitor in API 5 L X70 steel immersed in NaCl 3 % by different hydrodynamic conditions and theoretical study
Published 2025-09-01“…According to the SEM-EDS analysis, the metal's protection is evidenced by the formation of a α-D-glucofuranose monolayer on its surface, which isolates it from the corrosive environment. To explain the interactions and adsorption mechanism between the glucofuranose molecule and the API 5 L X70 steel surface, a computational approach was carried out at the density functional theory level with dispersion correction known as BPW91-D2/6–311++G(2d, 2p). …”
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6305
Exploring the inhibitory performance of expired moxifloxacin and norfloxacin on copper corrosion in saline environment
Published 2025-03-01“…In this report, two expired drugs, moxifloxacin and norflo¬xacin, were used as inhibitors for copper corrosion in 3.5 % NaCl solution at di¬f-ferent temperatures using several experimental approaches including chemical, electro¬chemical and spectroscopic techniques. The interaction of these two molecules on the copper surface was also inspected using different adsorption models. …”
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6306
Molecular insights into glioblastoma progression: role of CHCHD2P9 in tumor heterogeneity and prognosis
Published 2025-06-01“…Although the role of mitochondrial proteins in cancer has garnered increasing attention, their specific functions in the nervous system, particularly in gliomas, remain poorly understood.MethodsWe integrated single-cell RNA sequencing with cellular assays and flow cytometry to investigate the molecular characteristics and cellular interactions within glioblastoma subpopulations during tumor progression.ResultsSingle-cell RNA sequencing revealed several differentially expressed genes (DEGs) within glioblastoma subpopulations. …”
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6307
Assessment of Urethral Elasticity by Shear Wave Elastography: A Novel Parameter Bridging a Gap Between Hypermobility and ISD in Female Stress Urinary Incontinence
Published 2025-04-01“…Stress urinary incontinence (SUI) results from complex anatomical and functional interactions, including urethral mobility, muscle activity, and pelvic floor support. …”
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6308
Evaluation of thiocarbohydrazide derivative as corrosion inhibitor for C1018 carbon steel in 3.5% NaCl + 500ppm HAc solution: Electrochemical, SEM, FTIR and computational studies
Published 2024-12-01“…PHCT adsorbs, principally, using its NH2, C = S and C = C functional groups, based on FTIR characterization. Computational modeling using the FMO and MEP analyses confirmed that PHCT exhibits higher electron donating than electron accepting power and interacts with the metal surface through nitrogen and sulfur atoms. …”
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6309
Design, Synthesis, and Antifungal Analysis of Pyrazoline Derivatives Against <i>Candida</i> Species: A Comprehensive <i>In Vitro</i> and <i>In Silico</i> Approach
Published 2025-07-01“…Molecular docking and pharmacophore modeling have shown that 4e interacts efficiently with critical residues of lanosterol 14α-demethylase (CYP51). …”
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6310
Spatial immunogenomic patterns associated with lymph node metastasis in lung adenocarcinoma
Published 2024-10-01“…Additionally, we used multiplex immunohistochemistry (mIHC) on a propensity score-matched cohort, which enabled us to profile the immune microenvironment of primary tumors in detail while preserving cellular metaclusters, interactions, and neighborhood functional units. By integrating data from NGS and mIHC, we successfully identified spatial immunogenomic patterns and developed a predictive model for LN metastasis, which was subsequently validated independently. …”
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6311
Gender-specific effects of genetic variants within Th1 and Th17 cell-mediated immune response genes on the risk of developing rheumatoid arthritis.
Published 2013-01-01“…In phase 2, we genotyped these SNPs in 754 RA patients and 519 controls, leading to consistent gender-specific associations for Dectin-2 rs4264222, MCP-1 rs1024611, MCP-1 rs13900 and DC-SIGN rs4804803 polymorphisms in the pooled sample (OR = 1.38, 95%CI 1.08-1.77; OR = 0.74, 95%CI 0.58-0.94; OR = 0.76, 95%CI 0.59-0.97 and OR = 0.56, 95%CI 0.34-0.93). SNP-SNP interaction analysis of significant SNPs also showed a significant two-locus interaction model in women that was not seen in men. …”
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6312
BdNRT2A and BdNRT3.2 Are the Major Components of the High‐Affinity Nitrate Transport System in Brachypodium distachyon
Published 2025-06-01“…An effective nitrate transport in the heterologous expression system Xenopus oocytes required the coexpression of BdNRT2A and BdNRT3.2 that characterizes two‐component system of the HATS. Functional interaction between BdNRT2A‐GFP and BdNRT3.2‐RFP fusion proteins was observed at the plasma membrane in Arabidopsis protoplasts in transient expression experiments with BdNRT3.2 being necessary for the plasma membrane localization of BdNRT2A. …”
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6313
Genome-wide identification and gene expression analysis of the malate dehydrogenase (MDH) gene family in Eucalyptus grandis
Published 2025-08-01“…Malate dehydrogenases are pivotal in plant metabolism and stress responses, yet their evolutionary dynamics and functional diversification in woody angiosperms remain underexplored. …”
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6314
Nutrition-induced changes in the microbiota can cause dysbiosis and disease development
Published 2025-04-01“…Here, we report a causal link between environment-induced shifts in the microbiota and disease development. Using the model organism Hydra, we observed changes in microbial composition when transferring laboratory-grown Hydra to natural lake environments. …”
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6315
Effects of Workplace-Related Factors on the Prevalence of Fibromyalgia among Israeli Kindergarten Teachers
Published 2020-01-01“…Fibromyalgia syndrome (FMS), a chronic widespread pain disorder, has been associated with various models of stress, including those that are workplace-related. …”
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6316
Nano-Biochar Enhanced Adsorption of NO<sub>3</sub><sup>−</sup>-N and Its Role in Mitigating N<sub>2</sub>O Emissions: Performance and Mechanisms
Published 2025-07-01“…The results demonstrate that NBC exhibits nearly twice the NO<sub>3</sub><sup>−</sup>-N adsorption capacity compared to bulk biochar (BC), with adsorption behavior best described by a physical adsorption model. The enhanced adsorption performance was primarily attributed to NBC’s significantly increased specific surface area, pore volume, abundance of surface acidic functional groups, and higher aromaticity, which collectively strengthened multiple sorption mechanisms, including physical adsorption, electrostatic interactions, π–π interactions, and apparent ion exchange. …”
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6317
A comprehensive analysis of molecular characteristics of hot and cold tumor of gastric cancer
Published 2025-02-01“…Subsequently, 101 machine learning algorithm combinations were employed to construct a prognostic model based on the identified gene modules. Single-cell analysis was conducted to investigate cellular interactions associated with the immune-determinant gene module. …”
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6318
The Roles of Transcrustal Magma- and Fluid-Conducting Faults in the Formation of Mineral Deposits
Published 2025-05-01“…Experimental modeling of deep processes allowed us to identify the quantum character of crystal structure interactions of minerals with “inert” gases under elevated thermobaric conditions. …”
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6319
Health Care Social Robots in the Age of Generative AI: Protocol for a Scoping Review
Published 2025-04-01“…Generative artificial intelligence (AI) is an emerging technology with the potential to enhance the functionality of SR and promote user acceptance by further improving human-robot interaction. …”
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6320
Unveiling purine metabolism dysregulation orchestrated immunosuppression in advanced pancreatic cancer and concentrating on the central role of NT5E
Published 2025-04-01“…Moreover, cell development and cell-cell interaction analysis elucidated the alterations in TME induced by PM dysregulation. …”
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