Enhancement of in vitro digestive properties of silver carp (Hypophthalmichthys olivaceus) surimi gels by oxidized dihydromyricetin by Qianhui Yu, Jinlin Li, Qinye Yu, Yongjie Zhou, Yuqing Tan, Yongkang Luo, Hui Hong

“…Improving the digestibility of surimi products is key to boosting both their nutritional value and functional benefits. This study investigated how oxidized dihydromyricetin (oDMY) influences the digestion of silver carp surimi. …”
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YY1-induced Long non-coding RNA HOXA11-AS activates oxidative stress and inflammation by epigenetic modification of Nrf2 pathway to promote keloid formation by Jun Jin, Kai Wang, Chenxi Lu, Chenghao Yao, Feng Xie

“…An in vivo mouse xenograft model validated the findings.Results HOXA11-AS was upregulated in keloids. …”
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Co-expression of multi-genes for polynary perovskite electrocatalysts for reversible solid oxide cells by Xiaoxin Zhang, Hongyuan He, Yu Chen, Guangming Yang, Xiao Xiao, Haiping Lv, Yongkang Xiang, Shuxiong Wang, Chang Jiang, Jianhui Li, Zhou Chen, Subiao Liu, Ning Yan, Xue Yong, Abdullah N. Alodhayb, Yuanming Pan, Ning Chen, Jinru Lin, Xin Tu, Zongping Shao, Yifei Sun

“…This data-driven approach establishes a quantitative framework bridging entropy engineering and catalytic functionality in complex oxides.…”
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Preparation and characterization of a novel walnut peptide–calcium chelate and its role in promoting calcium absorption in calcium-deficient mice by Yaoxin Zhang, Xuehang Wang, Yuan Qi, Pengyuan Pan, Xiaoyi Li, Yue Leng, Ji Wang

“…Results showed that WP showed a calcium-binding capacity of 14.22 μg/mg, primarily through interactions with nitrogen and oxygen atoms. WP-Ca had good thermal stability and gastrointestinal digestive stability. …”
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Genomic insights and metabolic profiling of gut commensal Luoshenia tenuis at strain level by Xin-Wei Sun, Hao-Jie Huang, Yu-Zhi Zhao, Hao-Yu Chen, Chang-Yu Wang, Zheng Zhou, Yu Jiang, Run-Yu Han, He Jiang, Chang Liu, Shuang-Jiang Liu

“…Abstract Luoshenia tenuis, a newly identified gut commensal microbe from the family Christensenellaceae, has shown therapeutic effects on weight control and metabolic disorders in model mice. Bacterial strains are essential for investigations on the host-microbe interaction and further development of medical applications. …”
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4D structural biology–quantitative dynamics in the eukaryotic RNA exosome complex by Jobst Liebau, Daniela Lazzaretti, Torben Fürtges, Anna Bichler, Michael Pilsl, Till Rudack, Remco Sprangers

“…Here, we demonstrate that dedicated NMR experiments can provide quantitative insights into functionally important dynamic regions in very large asymmetric protein complexes. …”
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Pressure-induced structural phase transitions in CrSBr by Luther J. Langston, Alberto M. Ruiz, Carla Boix-Constant, Samuel Mañas-Valero, Eugenio Coronado, José J. Baldoví, Zhenxian Liu, Janice L. Musfeldt

“…By tracking how the phonons change under pressure, we uncover a remarkable chain of complex symmetry modifications, interlayer interactions, and chemical reactions. A group-subgroup analysis suggests that CrSBr undergoes an orthorhombic P m m n → monoclinic P2/m transition at 7.6 GPa, and based upon a comparison with model oxychlorides like FeOCl and CrOCl, we propose that changes in the pendant halide groups drive the system to a P21/m-like space group above 15.3 GPa. …”
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Super-enhancer-hijacking RBBP7 potentiates metastasis and stemness of breast cancer via recruiting NuRD complex subunit LSD1 by Yuanyin Xi, Ruoding Wang, Man Qu, Qinwen Pan, Minghao Wang, Xiang Ai, Zihan Sun, Chao Zhang, Peng Tang, Jun Jiang, Ying Hu

“…The PDOs and PDX models were used to assess the clinical significance of ORY-1001 in suppressing BCa. …”
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Enhancing the structural and optoelectronic properties of carboxymethyl cellulose sodium filled with ZnO/GO and CuO/GO nanocomposites for antimicrobial packaging applications by Rania Badry, Noha M. Sabry, Medhat A. Ibrahim

“…These results were confirmed by the quantum mechanical calculations utilizing density functional theory (DFT). Total dipole moment (TDM), frontier molecular orbitals (FMOs), chemical reactivity descriptors, and molecular electrostatic potential (MESP) maps were all studied using the B3LYP/LanL2DZ model. …”
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Identification of Genes for Improving Cold Sensitivity in Nerve-Damaged Rats Via Lumbar Sympathectomy Using Poly(A)-seq by Xi Meng, Hanrui Fan, Ping Xu, Lei Yang, Yong Fei, Wenping Zhang

“…Poly(A)-seq identified 278 DEGs (177 upregulated and 101 downregulated) in the spinal cords of SNI model rats compared with control rats. We identified 174 DEGs in the gene expression profile of lumbar sympathectomized SNI rats, including 69 upregulated and 105 downregulated genes, compared with SNI model rats. …”
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Integrated bioinformatics and experiment validation reveal cuproptosis-related biomarkers and therapeutic targets in sepsis-induced myocardial dysfunction by Xuemei Shi, Zhonghan Yan, Ruilin Ding, Fenfen Xia, Yan Du, Xiaojie Wang, Qing Peng

“…Diagnostic genes were selected through SVM–RFE, LASSO, and random forest models. Additionally, potential gene-targeting agents were predicted using drug-gene interaction analysis. …”
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CLN-619, a MICA/B monoclonal antibody that promotes innate immune cell-mediated antitumor activity by Naveen K Mehta, Kristan Meetze, Patrick A Baeuerle, Jennifer S Michaelson, Kerry A Whalen, Kavya Rakhra, Catherine C Henry, Safak Yalcin, Neil W Gibson

“…Potent antitumor activity of CLN-619 as a monotherapy was observed in several preclinical models. Activity of CLN-619 required a functional Fcγ1 domain, suggesting the requirement of simultaneous engagement of NKG2D and cluster of differentiation 16A (CD16A) on immune cells for optimal cytotoxicity. …”
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Application of Post-Occupancy Evaluation in the Design of Collegiatae Educational Space: (Case study: Faculty of Arts and Architecture, Islamic Azad University-Tehran South Branch) by Reza Naghdbishi, Zeinab Gohari

“…By engaging users and designers in a two-way interaction, the aim is to enhance building residents' satisfaction and improve overall performance.The research focuses on assessing the alignment between user needs and the functional response of the building, comparing these responses to established design standards. …”
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An empirical study of the naïve REINFORCE algorithm for predictive maintenance by Rajesh Siraskar, Satish Kumar, Shruti Patil, Arunkumar Bongale, Ketan Kotecha, Ambarish Kulkarni

“…For the REINFORCE, a basic hyperparameter sensitivity and interaction analysis is conducted to better understand the dynamics and present results for the hyperparameters learning rate, discount factor $$\gamma$$ γ and the network activation functions (ReLU and Tanh). …”
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THE LEARNING PROCESS FROM THE PERSPECTIVE OF INTERDISCIPLINARY RESEARCH by I. M. Osmolovskaya, L. A. Krasnova

“…Moreover, interdisciplinary research provides the effective design of various learning models in a scientifically rigorous context.…”
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The mechanism of RNA methylation writing protein-related prognostic genes in lung adenocarcinoma based on bioinformatics by Sha Yin, Guangyan Luo, Lei Luo

“…In addition, genes’ potential functions and regulatory mechanisms were explored through gene-gene interaction (GGI) networks and competing endogenous RNA (ceRNA) networks.ResultsWe selected 202 genes associated with RNA methylation writer proteins, from which we identified the three genes (CLEC3B, GRIA1, and ANOS1). …”
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Tectona Grandis seed powder and Mangifera Indica leaf powder as bio adsorbents for removal of methylene blue from aqueous solution by Divya N. Shetty, Vinola A. Lobo, Suman Rani, Narasimha Raghavendra

“…The adsorption process were more in line with the Langmuir model than the other models. At neutral pH (7), TG showed maximum percentage removal of 73.12 % whereas, MI powder showed a maximum percentage removal of 50.5 %. …”
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High expression of SOX9 is a diagnostic and prognostic indicator of glioma by Libo Xu, Zhenhao Wang, Mao Li, Qingsong Li

“…In recent years, SOX9 has been reported to play an important role in many diseases and cancers, and is a promising target, but it has been rarely reported in GBM.MethodsRNA sequencing data of GBM were obtained from the Cancer Genome Atlas (TCGA) database and the Genotype-Tissue Expression (GTEx) database for analysis of SOX9 expression and differentially expressed genes (DEGs). Moreover, functional enrichment analysis of GBM-related DEGs was performed by GO/KEGG, GSEA, and protein-protein interaction (PPI) network. …”
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Brake rigging dynamic simulation under braking on a track section with irregularities (the case of a passenger car) by I. A. Yaitskov, V. V. Kosarevskii

“…The subject of the study is the force interaction of the elements and dynamic processes in the brake system of passenger cars.Materials and Methods. …”
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Deep Cleaning of Crystal Violet and Methylene Blue Dyes from Aqueous Solution by Dextran-Based Cryogel Adsorbents by Maria Marinela Lazar, Roxana P. Damaschin, Irina Volf, Maria Valentina Dinu

“…Moreover, the average pore sizes of the DxPF cryogels loaded with dyes further decreased from 42.30 ± 7.96 μm to 23.68 ± 2.69 μm, indicating a strong interaction between the functional groups of the cryogel matrix and those of the dye molecules. …”
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