Distinct network patterns emerge from Cartesian and XOR epistasis models: a comparative network science analysis by Zhendong Sha, Philip J. Freda, Priyanka Bhandary, Attri Ghosh, Nicholas Matsumoto, Jason H. Moore, Ting Hu

“…In contrast, the exclusive-or (XOR) epistatic model has shown promise in detecting a broader range of epistatic interactions and revealing more biologically relevant functions associated with interacting variants. …”
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Associations of one-carbon metabolism, related B-vitamins and ApoE genotype with cognitive function in older adults: identification of a novel gene-nutrient interaction by Shane Gordon, Leane Hoey, Helene McNulty, Jordan Keenan, Faith Pangilinan, Lawrence C. Brody, Mary Ward, J. J. Strain, Liadhan McAnena, Adrian McCann, Anne M. Molloy, Conal Cunningham, Kevin McCarroll, Catherine F. Hughes

“…We examined associations between folate, B12, B6, riboflavin, and cognitive function in older adults, including interactions with the ApoE ε4 genotype. …”
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Multiple Chaperone DnaK–FliC Flagellin Interactions are Required for Pseudomonas aeruginosa Flagellum Assembly and Indicate a New Function for DnaK by Gabriella Molinari, Sara S. Ribeiro, Katrin Müller, Benjamin E. Mayer, Manfred Rohde, Alejandro Arce‐Rodriguez, Juan José Vargas‐Guerrero, Albert Avetisyan, Josef Wissing, Werner Tegge, Lothar Jänsch, Mark Brönstrup, Antoine Danchin, Martina Jahn, Kenneth N. Timmis, Simon Ebbinghaus, Dieter Jahn, José Manuel Borrero‐de Acuña

“…Remarkably, in vitro fast relaxation imaging (FReI) experiments mimicking ATP‐deprived extracellular environment conditions exhibited DnaK ATP‐independent holdase activity, regardless of its co‐chaperone DnaJ and its nucleotide exchange factor GrpE. We present a model for the DnaK‐FliC interactions involving dynamic states throughout the flagellum assembly stages. …”
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Interaction between APOE Ɛ4 status, chemotherapy and endocrine therapy on cognitive functioning among breast cancer survivors: the CANTO-Cog longitudinal study by Mylène Duivon, François Christy, Emilie Thomas, Justine Lequesne, Hélène Castel, Catherine Gaudin, Dominique Delmas, Sandrine Boyault, Olivier Rigal, Chayma Bousrih, Christelle Lévy, Florence Lerebours, Antonio Di Meglio, Patricia A. Ganz, Kathleen Van Dyk, Ines Vaz Luis, Marie Lange, Florence Joly

“…We fitted logistic and linear mixed models to assess associations of APOE4 status with cognitive impairment over time and interactions of APOE4 with CT and ET. …”
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Molecular structure data and modelling roadmap for optimized oxidized graphene quantum dot and epoxy interface and mechanical propertiesMendeley Data by Prathamesh Deshpande, Robert Chan-Jobe, Ozgur Keles

“…Their small size enables simultaneous enhancement of stiffness, strength and toughness. In addition, functionalization of these materials enables other supramolecular interactions like hydrogen bonding which improve the interfacial interaction with the epoxy. …”
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Agarose Hydrogels Enriched by Humic Acids as a Functional Model for the Transport of Pharmaceuticals in Nature Systems by Martina Klučáková, Petra Závodská

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Brain organoid models for studying the function of iPSC-derived microglia in neurodegeneration and brain tumours by Angelica Maria Sabogal-Guaqueta, Teresa Mitchell-Garcia, Jasmijn Hunneman, Daniëlle Voshart, Arun Thiruvalluvan, Floris Foijer, Frank Kruyt, Marina Trombetta-Lima, Bart J.L. Eggen, Erik Boddeke, Lara Barazzuol, Amalia M. Dolga

“…The interplay between microglia and other cells in the central nervous system, such as neurons or other glial cells, influences the function and ability of microglia to respond to various stimuli. …”
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Pattern formation with jump discontinuity in a predator–prey model with Holling-II functional response by Gaihui Guo, Xiaoyi Yang, Conghui Zhang, Shanbing Li

“…This paper is focused on the existence and uniqueness of nonconstant steady states in a reaction–diffusion–ODE system, which models the predator–prey interaction with Holling-II functional response. …”
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Systematic review and consensus conceptual model of meaningful symptoms and functional impacts in early Parkinson’s Disease by Jennifer R. Mammen, Jamie L. Adams, Rikki Mangrum, Yuge Xiao, William Barbosa, Mirinda Tyo, Christopher Redmond, Cheryl Carter, Kelly Cifelli, Robert Cifelli, Hope Maruzo, Jim Meeker, Gerry Shultz, Colbren Thomas, Claire Bale, Evan Davies, Catherine M. Kopil, Connie Marras, Tiago Mestre, Thomas Morel, Tanya Simuni, Glenn T. Stebbins, Daniel Weintraub, Diane Stephenson

“…Abstract A comprehensive, patient-centered conceptual model of early Parkinson’s is lacking and is greatly needed. …”
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A Stage Structure Prey Predator Model Using Pentagonal Fuzzy Numbers and Functional Response by Vinothini Palani, Kavitha Krishnan

“…The interaction between the species is done by using functional responses, such as the Holling type I reaction for immature prey and the Crowley Martin functional response for mature prey. …”
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MATHEMATICAL MODEL OF THE FUNCTIONING PROCESS OF A RUBBER BUSHING ON THE HOOKE AND SAINT-VENANT ELEMENTS’ BASIS by D. A. Tikhov-Tinnikov, V. S. Baradiev, A. I. Fedotov, A. V. Alekseev

“…The paper presents a mathematical description of the bushing simulation functioning results, accuracy of approach, areas of application of the mathematical model.Materials and methods. …”
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Cognitive model of the national financial market: creating process and prospects for assessing the security of its functioning by E. A. Loktionova

“…The aim of the study is to develop a cognitive model of the Russian financial market to assess the security of its functioning. …”
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Decellularized liver scaffolds for constructing drug-metabolically functional ex vivo human liver models by Juan Liu, Ariel Hanson, Wenzhen Yin, Qiao Wu, Eliane Wauthier, Jinmei Diao, Timothy Dinh, Jeff Macdonald, Ruihong Li, Masahiko Terajima, Mitsuo Yamauchi, Ziye Chen, Praveen Sethupathy, Jiahong Dong, Lola M. Reid, Yunfang Wang

“…We have developed a bioengineered, perfused, organ-level human liver model that accurately replicates key liver functions, including metabolic activities, and protein synthesis, thus addressing some of the limitations associated with traditional liver monolayers, organoids, and matrix-embedded liver cells. …”
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A Multicellular In Vitro Model of the Human Intestine with Immunocompetent Features Highlights Host‐Pathogen Interactions During Early Salmonella Typhimurium Infection by Spyridon Damigos, Aylin Caliskan, Gisela Wajant, Sara Giddins, Adriana Moldovan, Sabine Kuhn, Evelyn Putz, Thomas Dandekar, Thomas Rudel, Alexander J. Westermann, Daniela Zdzieblo

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CHCHD4 Oxidoreductase Activity: A Comprehensive Analysis of the Molecular, Functional, and Structural Properties of Its Redox-Regulated Substrates by Nicole Balasco, Nazanine Modjtahedi, Alessandra Monti, Menotti Ruvo, Luigi Vitagliano, Nunzianna Doti

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Neural Cell Interactions with a Surgical Grade Biomaterial Using a Simulated Injury in Brain Organotypic Slices by Jessica Patricia Wiseman, Divya Maitreyi Chari

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Interaction of brequinar and analogs with PD-L1: a molecular docking analysis by Gérard Vergoten, Christian Bailly

“…Methods: The present study evaluated the capacity of BQR to interact directly with the PD-L1 protein dimer using molecular modeling. …”
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Modeling of Ozone Interactions with Various Air Pollutants and Meteorological Factors Using Jaya and Teaching-Learning Based Optimization (TLBO) Algorithms by Nurcan Öztürk

“…Some statistical indices have been applied to evaluate the performance of these models. In conclusion, it is shown that Jaya and TLBO algorithms can be used in the optimization of the regression function coefficients in modelling some air pollutants interactions and the best-fit equation for each parameter is obtained from the quadratic function.…”
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Linolenic acid-enriched supercritical carbon dioxide extract from seeds of Phyllanthus emblica L., a functional food with quorum quenching and anti-biofilm action, rescues Caenorha... by Acharya Balkrishna, Nem Kumar Ngpoore, Saurabh Bhatti, Yash Varshney, Manisha Kabdwal, Pardeep Nain, Rishabh Dev, Savita Lochab, Anurag Varshney

Subjects: “…Functional food…”
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Auditory evoked-potential abnormalities in a mouse model of 22q11.2 Deletion Syndrome and their interactions with hearing impairment by Chen Lu, Jennifer F. Linden

“…It is not known if these risks interact. Here we used the Df1/+ mouse model of the 22q11.2 deletion to investigate how hearing impairment might interact with increased genetic vulnerability to psychiatric disease to affect brain function. …”
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