Temporal GeneTerrain: advancing precision medicine through dynamic gene expression visualization by Ehsan Saghapour, Ehsan Saghapour, Rahul Sharma, Delower Hossain, Delower Hossain, Kevin Song, Kevin Song, Zhandos Sembay, Zhandos Sembay, Jake Y. Chen, Jake Y. Chen

“…Conventional visualization techniques, such as heatmaps and static clustering, often fail to effectively capture these temporal dynamics, particularly when analyzing large-scale multidimensional datasets. …”
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Mechanistic insights into Jianpi Qinghua Sanyu Yin treatment of raised erosive gastritis: ceRNA-mediated PI3K/AKT signaling pathways by Liya Liu, Liya Liu, Liya Liu, Ying Cheng, Ying Cheng, Guosheng Lin, Guosheng Lin, Huifang Zheng, Huifang Zheng, Xinran Zhang, Xinran Zhang, Peilin Zhao, Peilin Zhao, Meixuan Guo, Meixuan Guo, Qihong Liu, Qihong Liu, Wenyi Fang, Wenyi Fang, Wenrong Wang, Wenrong Wang, Anjum Jafri, Aling Shen, Aling Shen, Xiao Ke, Xiao Ke, Youqin Chen

“…This study aimed to investigate the potential mechanism of JPQHSYY’s therapeutic effects on REG.MethodsRNA-seq was employed to systematically analyze mRNA, lncRNA, and miRNA profiles in gastric mucosal tissues from REG patients before and after JPQHSYY treatment. …”
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Inspiring Social Capital Through Community Green Space: Pathways and Implications by Lin YE, Shi HE, Yinghao LI, Zhaohui YAN, Lei HUANG

“…First, green spaces act as important gathering places that encourage social interaction. Second, the interaction of social networks, trust, and norms is facilitated by social interactions in green spaces. …”
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Identification and leveling of factors affecting the acceptance of excellence model in Islamic Azad University by Seyedeh Somayeh Mousavi Siah Deleh, Samad Jabbari Asl, Musa Rezvani Chaman Zamin

“…The data collection tool is a semi-structured interview. In order to analyze the data, the theme analysis method was used, and in order to level the identified criteria, the interpretive structural modeling method was used in MACMIC software. …”
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Lactylation-related gene signature accurately predicts prognosis and immunotherapy response in gastric cancer by Xuezeng Sun, Haifeng Dong, Rishun Su, Jingyao Chen, Wenchao Li, Songcheng Yin, Changhua Zhang

“…Utilizing both anti-lactylation and anti-PD-L1 may prove to be an effective approach for treating GC in clinical settings. …”
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FCGR1A Alleviates Ischemic Stroke-induced Injury by Promoting Anti-Inflammatory Microglial Polarization via the AMPK–mTOR Signaling Pathway by Meng Liu, Xuhui Fan, Dongya Chen, Huibin Yao, Zhihui Huang, Heng Li, Qing Zhang, Yuqi Wang, Haihan Song, Yufeng Yan

“…Hub genes were found by analyzing protein–protein interaction (PPI) networks. …”
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Interlacing biology and engineering: An introduction to textiles and their application in tissue engineering by S. Scholpp, L.A. Hoffmann, E. Schätzlein, T. Gries, C. Emonts, A. Blaeser

“…Electrospinning, though highly effective in mimicking the ECM, is structurally limited. …”
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Fungal Footprints: Soil Fungal Communities in Black Walnut and Red Oak Forests by Shaneka S. Lawson, Juan P. Frene, Niall D. Lue Sue

“…Our study underscores that grasping these specific interactions is essential for effective forest management, especially when considering how to use fungal communities to boost plant growth. …”
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Neuronal guanine nucleotide exchange factor promotes the axonal growth and cancer cell proliferation via Ephrin-A3/EphA2 axis in lung adenocarcinoma by Jie Mi, Wentian Zhang, Yijiu Ren, Lei Zhu, Bei Yang, Hao Wang, Liang Duan

“…In animal model, NGEF overexpression significantly promoted tumor growth and increased the density of nerve fibers, and these effects were inhibited by ALW-II-41-27. Conclusions NGEF facilitates the infiltration of nerve and the growth of cancer cells in lung adenocarcinoma through the Ephrin-A3/EphA2 pathway, suggesting that NGEF is a promising target for disrupting interactions between nerves and tumors. …”
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Bank’s Credit Portfolio Optimization Using Actuarial Approach and Artificial Neural Networks by Saeed Bajalan, Saeid Fallahpour, Sara Raeesi

“…Considering the need to establish an optimal credit allocation and adopt effective policies, this study aims to develop an optimal model for credit allocation across economic sectors. …”
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Construction and clinical application of a risk model based on N6-methyladenosine regulators for colorectal cancer by Hanhan Zhu, Yu Yang, Zhenfeng Zhou

“…Method The bulk RNA-seq data from the Atlas and Compass of Immune-Colon cancer-Microbiome interactions (AC-ICAM) and GSE33113 CRC datasets were obtained from the cBioportal and GEO databases, and a total of 21 m6A regulators genes were collected from a previous study. …”
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Methodological Challenges in Randomized Controlled Trials of mHealth Interventions: Cross-Sectional Survey Study and Consensus-Based Recommendations by Jesus Lopez-Alcalde, L Susan Wieland, Yuqian Yan, Jürgen Barth, Mohammad Reza Khami, Siddharudha Shivalli, Cynthia Lokker, Harleen Kaur Rai, Paul Macharia, Sergi Yun, Elvira Lang, Agnes Bwanika Naggirinya, Concepción Campos-Asensio, Leila Ahmadian, Claudia M Witt

“…ObjectiveWe aimed to identify specific methodological challenges in RCTs testing mHealth interventions’ effects and develop consensus-based recommendations to address selected challenges. …”
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Thermo-hydro-mechanical coupling mechanisms and sensitivity analysis of abandoned mine thermal energy storage systems by Liyuan LIU, Yaohui LI, Tao WANG, Tongbin ZHAO, Qiang KOU, Zerui MI, Le ZHANG

“…A three-dimensional thermo-hydro-mechanical (THM) coupled numerical model is developed to calculate the coupled effects over a decade of system operation and analyze heat transfer processes along with stress variation patterns in the roadway’s surrounding rock. …”
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Antibacterial and antibiofilm activities of star anise-cinnamon essential oil against multidrug-resistant Salmonella Thompson by Jie Zhang, Jie Zhang, Dapei Zhang, Yanhua Chen, Yongyu Gong, Binfang Yuan, Zhiyuan Mo, Haibo Tang, Haibo Tang, Junyu Tao, Junyu Tao, Ziheng Xu

“…The FIC index calculated was 0.375, which suggests a synergistic interaction between the two. When SCEO was used in combination at specific ratios, it demonstrated enhanced antibacterial and anti-biofilm capabilities compared to the individual effects of CEO or SAEO, potentially through the disruption of bacterial cell membranes and cell walls. …”
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HIV infection drives proinflammatory adipocyte differentiation in an in vitro model and reveals a new inflammatory pathway by Rosa Nicole Freiberger, Cynthia Alicia Marcela López, Franco Agustin Sviercz, Patricio Jarmoluk, María Belén Palma, María Belén Palma, Marcela Nilda García, Jorge Quarleri, M. Victoria Delpino

“…Researchers assessed adipogenesis by analyzing lipid droplet formation, expression of adipogenic transcription factors (C/EBPα, C/EBPβ, PPAR-γ), lipogenic/lipolytic enzymes, SREBPs, cytokine secretion, and the effects of CXCR4 and CCR5 with specific inhibitors.ResultsHIV exposure influences adipogenesis, increasing lipid droplet size in a tropism dependent manner and upregulating key adipogenic factors such as C/EBPα, C/ EBPβ, and PPAR-γ. …”
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Distribution of Size-Fractionated Phytoplankton and Their Relationships with Environmental Variables in Bivalves Mariculture Areas of Haizhou Bay by Xue GONG, Jihong ZHANG, Xinmeng WANG, Wenguang WU, Rongzhao MENG, Liushuyi TAN, Haojie MA

“…Two-way variance and redundancy analyses were used to analyze the effects of environmental factors on size-fractionated phytoplankton. (1) The annual variation range of total Chl-a concentration in the investigated area was 0.86–18.49 µg/L, and the seasonal difference was significant (P < 0.05). …”
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“Locality – Adaptation” Research of Hydropower Resettlement Communities in the Jinsha River Basin: A Case Study of Ludila Hydropower Station by Fang WANG, Zhuoqi LI, Haoyi XU, Jiaqi YAN

“…By connecting the drastic environmental effects at the basin level with human behavioral responses at the settlement level, the research visually demonstrates how hydropower projects trigger residential space reconstruction through land resource constraints. …”
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The value-added model of the supply chain of petrochemical industries with a sustainable development approach by ali amiri, seyed abbas heydari, vahidreza Mirabi

“…The tool for gathering information is an interview. To collect and analyze data, Delphi technique was used to identify components. …”
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Long-Term Outcomes of a Health Information System-Based Feedback Intervention Study of Antimicrobial Prescriptions in Primary Care Institutions: Follow-Up of a Randomized Cross-Ove... by Yan Y, Yang J, Lu Y, Cui Z, Chang Y

“…The time-intervention interaction was utilized to evaluate the changing trends of group A and group B. …”
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In Vitro Characterization of the Immune Response to an Epitope Ensemble Vaccine Against Rhinovirus in Pediatric Asthma and Adults With Chronic Obstructive Pulmonary Disease: Protoc... by Sara Alonso Fernandez, Raquel Reyes-Manzanas, Susana Camara, Juan Mozas-Gutierrez, Myriam Calle-Rubio, Juan Rodriguez-Hermosa, Andres Bodas-Pinedo, Santiago Rueda Esteban, Esther M Lafuente, Jesús Reiné, Pedro A Reche

“…A detailed characterization of these immune responses will provide critical insights into host-pathogen interactions and may serve as a foundation for the development of effective T-cell–based vaccines or immunotherapies targeting HRV. …”
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