Deletional Alpha-Thalassemia Alleles in Amazon Blood Donors by Fernanda Cozendey Anselmo, Natália Santos Ferreira, Adolfo José da Mota, Marilda de Souza Gonçalves, Sérgio Roberto Lopes Albuquerque, Nelson Abrahim Fraiji, Ana Carla Dantas Ferreira, José Pereira de Moura Neto

“…Alpha-thalassemia screening was carried out between 2016 and 2017 among 714 (72.1%) male and 275 (27.9%) female donors. The aims of this analysis were to describe the distribution of various alpha-thalassemia alleles by gender, along with their genotypic interactions, and to illustrate the hematological changes associated with each phenotype. …”
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Study on immunogenicity of recombinant ferritin hemagglutinin of canine distemper virus by Dongyu Liu, Bing Liu, Jinling Guo, Yanan Zhao, Dandan Yang, Yudie Zhang, Congmei Wu, Yuhe Yin

“…Methods In this study, H protein sequences were analyzed by conservation analysis and prediction of multiple immune cell epitopes, three possible epitope sequences were identified. …”
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Participatory Intervention Development of a Peer-Guided Self-Help App for Anxiety Disorders: Mixed Methods Study by Laura Duddeck, Timo Stolz, Christian Zottl, Thomas Berger, Johanna Boettcher

“…Peer-guided self-help apps offer a cost-effective alternative to traditional care, reaching those who might otherwise remain untreated. …”
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Discussion of the correlation between HIV-1 gp120-induced intestinal dysbiosis and intestinal barrier loss by Ms Jiachun Luo, Anyun Wang, Yuqi Wang, Yuyi Che, Xingyu Wan, Qiuming Peng, Dr Xuefeng Gao, Mr. Xuefeng Gao

“…And mouse IL-1β level in the tissue supernatant were detected by using IL-1β Meike Bio ELISA kits. Results: 16S rRNA analysis indicated that there are significant differences in fecal bacterial diversity in Tgm and WT mice. …”
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Functional Verification of Extended Kalman Filter on FPGA for Railway Wheelset Parameters Estimation by Khakoo Mal, Tayab Din Memon, Imtiaz Hussain Kalwar, Allah Rakhio Junejo, Majid Hussain Memon, Tarique Rafique Memon, Sufyan Ali Memon, Bhawani Shankar Chowdhry

“…Hence properly estimation of wheel-rail contact conditions with real-time implementation on FPGA can meet the expectation that railway vehicles would be extremely fast, comfortable, safe, and cost-effective modes of transportation worldwide.INDEX TERMS Adhesion conditions, accuracy index, extended Kalman filter, FPGA synthesis, simulation.…”
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Long Non-Coding RNA EPB41L4A-AS1 Serves as a Diagnostic Marker for Chronic Periodontitis and Regulates Periodontal Ligament Injury and Osteogenic Differentiation by Targeting miR-2... by Li R, Huang Z, Chen M

“…The diagnostic significance of EPB41L4A-AS1 was evaluated using receiver operating characteristic (ROC) analysis. The levels of inflammatory factors were measured using an enzyme-linked immunosorbent assay. …”
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Association Between HLA Class II Gene Polymorphisms and Cytokine Levels in PLWH with HIV-Related Dermatoses in Latvia by Alena Soha, Inga Azina, Maksims Zolovs, Darja Arina Miskina, Viktorija Murasko, Baiba Rozentale, Ilona Hartmane, Andris Rubins

“…Increased IL-1β levels may enhance immune responses, while higher IL-10 levels may exert anti-inflammatory effects, potentially reducing susceptibility to HIV-related dermatoses. …”
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Addictive behaviour of adolescents and young men in the education system: Review of psychological and pedagogical research by S. A. Minyurova, O. V. Kruzhkova, I. V. Vorobyeva, A. I. Matveeva

“…In addition, difficulties in learning and interacting with other subjects of the educational environment may (among other things) be a factor stimulating the emergence of addictive behaviour as a form of care or compensation. …”
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Think Before You Take: Understanding Adult Medication Literacy in Saudi Arabia by Alhomoud F, Alsaeed W, Alzainaldain F, Alelq K, Alhomoud FK, Alamer KA, Alsultan MM, Alqarni YS, Alshehail B, Alhifany AA

“…Other issues included refills, drug use in pregnancy, storage and disposal, expiration date, adverse effects, drug interactions, missed doses, label understanding, tablet splitting, and duration of therapy. …”
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Exploring Youth Perspectives on Digital Mental Health Platforms: Qualitative Descriptive Study by Sarah Daniel, Lauren Volcko, Emilie Bassi, Julia Hews-Girard, Katherine Bright, Marianne Barker, Lia Norman, Karina Pintson, Geneca Henry, Sumaya Soufi, Chukwudumbiri Efrem Omorotionmwan, Melanie Fersovitch, Leanne Stamp, Karen Moskovic, David W Johnson, Gina Dimitropoulos

“… Abstract BackgroundThe increasing prevalence of mental health disorders among youth underscores the need for accessible and effective interventions. Digital mental health (dMH) platforms like Innowell offer promising solutions by increasing access to mental health care for young people. …”
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A Model for Creating and Implementing Ambidextrous Innovation in Iranian Banking by Vahid Khashei Varnamkhasti, Sajad Farsi

“…The data collected was used to develop a self-interaction matrix and to proceed through the stages of structural-interpretive modeling (ISM). …”
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Focus on reflective competence: A triangulation to examine youth soccer coaches' reflective competence by Max Danner, Mareike Ahns, Günter Amesberger

“… Introduction & Purpose Coaching is recognized as a complex socio-educational interaction (Jones, 2007), a view supported by the German Football Association (DFB). …”
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A Spatial Shift in Flood–Drought Severity in the Decades Surrounding 2000 in Xinjiang, China by Sulei Naibi, Anming Bao, Ye Yuan, Jiayu Bao, Rafiq Hamdi, Tao Yu, Xiaoran Huang, Ting Wang, Tao Li, Jingyu Jin, Gang Long, Piet Termonia

“…While prior studies have explored the relationship between climate extremes and flood–drought dynamics, few have analyzed these interactions at different time and spatial scales using different method combinations. …”
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Sources of cigarettes for youth smokers in Malaysia: Findings from the National Health and Morbidity Survey (NHMS) 2022: Adolescents Health Survey (AHS) by Kuang Hock Lim, Yoon Ling Cheong, Kuang Kuay Lim, Jia Hui Lim, Hamizatul Akmal Abdul Hamid, Mohd Ruhaizie Riyadzi, Sumarni Mohd Ghazali, Chee Cheong Kee, Cheah Yong Kang, Chong Shao Hui, Ali Aman Marine, Mohd Hazilas Mat Hashim, Hui Li Lim

“…Introduction Developing effective intervention programs to lower adolescent smoking requires a thorough understanding of the sources and methods of youth tobacco product acquisition. …”
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Reverse vaccinology and immunoinformatics approaches for multi-epitope vaccine design against Klebsiella pneumoniae reveal a novel vaccine target protein by Mayada M. Elfadil, Samah Omer A. Samhoon, Moaaz M. Saadaldin, Sabah A.E. Ibrahim, Ahmed Abdelghyoum M. Mohamed, Omnia H. Suliman, Osama Mohamed, Nadzirah Damiri, Mohd Firdaus-Raih, Sofia B. Mohamed, Qurashi. M. Ali

“…Additionally, CABSflex 2.0 dynamics analysis confirmed stable vaccine–TLR4 interactions, with minimal residue-level fluctuations (RMSF <1.5 Å), indicating conformational stability of the complex. …”
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YWHAG promotes bladder cancer metastasis by regulating TMOD3 to activate ERK1/2 and JNK phosphorylation in the MAPK pathway by Tai Tian, Shiming He, Han Hao, Bao Guan, Yanqing Gong, Jian Fan, Zhenpeng Zhu, Wenzhi Gao, Yucai Wu, Ninghan Feng, Aixiang Wang, Yuexian Guo, Xuesong Li

“…Finally, TMOD3 knockdown experiments were conducted to verify whether the pro-metastatic effects of YWHAG in bladder cancer are mediated through TMOD3. …”
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Integrating multi-omics data reveals the antitumor role and clinical benefits of gamma-delta T cells in triple-negative breast cancer by Guixin Wang, Shuo Wang, Wenbin Song, Chenglu Lu, Zhaohui Chen, Long He, Xiaoning Wang, Yizeng Wang, Cangchang Shi, Zhaoyi Liu, Yue Yu, Xin Wang, Yao Tian, Yingxi Li

“…Results The γδT cell infiltration was closely associated with favorable prognosis in triple-negative breast cancer (TNBC) but not in other subtypes of breast cancer. γδT cells may exert antitumor effects through intrinsic lineage evolution or interact with antigen-presenting cells through ligand-receptor pairs. …”
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Early mental health intervention and supported self-care for LGBTQ+ young people in the UK: a mixed-methods study by Elizabeth McDermott, Rachael Eastham, Elizabeth Hughes, Emily Pattison, Katherine Johnson, Stephanie Davis, Steven Pryjmachuk, Ceu Mateus, Olu Jenzen, Felix McNulty

“…We used a four-stage data analysis strategy that was both deduction/inductive and within-case/cross-case. …”
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Timing of unsaturated fat intake improves insulin sensitivity via the gut microbiota-bile acid axis: a randomized controlled trial by Chunbo Wei, Xiaoqing Xu, Jia Zhang, Xuanyang Wang, Tianshu Han, Yingfeng Zhang, Sijia Pan, Zhu Ming, Ran Li, Fengge Lou, Yu Cheng, Huan Xu, Xingyuan Sun, Guannan Geng, Yujun Pan, Qianmin Liu, Haitao Qi, Xuemin Yan, Keke Dang, Jiaofeng Zhou, Changhao Sun, Ying Li

“…This 12-week, double-blind, randomized, controlled, 2 × 2 factorial-designed feeding trial investigated the effects of timing (lunch or dinner) and types of dietary USFA (high monounsaturated fat or polyunsaturated fat diet) intake on glucose metabolism in seventy prediabetes participants (mean age, 57 years). …”
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VASP, HCLS1, MSN, and EZR: Key molecular beacons in the pathophysiology of perihematomal edema Post-Intracerebral hemorrhage by Jingjing Chen, Yi Zhong, Xueshun Xie, Guannan Jiang, Lei Bai, Haiying Li, Xiang Li, Ximing Wang, Gang Chen

“…Extensive enrichment analysis and protein interactions were performed to examine the expression and clinical significance of the identified genes. …”
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