Role of VapBC4 toxin-antitoxin system of Sulfolobus acidocaldarius in heat stress adaptation by Arghya Bhowmick, Alejandra Recalde, Chandrima Bhattacharyya, Ankita Banerjee, Jagriti Das, Ulises E. Rodriguez-Cruz, Sonja-Verena Albers, Abhrajyoti Ghosh

“…Toxins can cause cell death, reversible growth stasis, and direct inhibition of crucial cellular processes through various mechanisms, while antitoxins neutralize the effects of toxins. In bacteria, these systems have been studied in detail, whereas their function in archaea remains elusive. …”
Get full text

Health professions education in Serbia: Evaluation and measures for quality improvement through experiential education, interprofessional education and teaching competencies develo... by Kovačević Milena, Odalović Marina, Đukić-Ćosić Danijela, Vasiljević Dragana, Parojčić Jelena, Tasić Ljiljana

“…A comprehensive situation analysis was performed among academic staff, healthcare practitioners, and healthcare science students to address and respond to new trends. …”
Get full text

Evaluation of a Novel eHealth Tool for Pulmonary Rehabilitation in People With Chronic Obstructive Pulmonary Disease: Randomized Controlled Pilot and Feasibility Trial by Åsa Karlsson, Pernilla Sönnerfors, Sara Lundell, Annika Toots, Karin Wadell

“…The test procedures seemed feasible, although the recruitment process needs further consideration. The effectiveness of the intervention remains to be evaluated in a future larger trial. …”
Get full text

Putting measurement-based care into action: a multi-method study of the benefits of integrating routine client feedback in coordinated specialty care programs for early psychosis by Piper Meyer-Kalos, Grace Owens, Melissa Fisher, Lionel Wininger, Anne Williams-Wengerd, Kimberleigh Breen, Josephine Pita Abate, Ariel Currie, Nathan Olinger, Sophia Vinogradov

“…Abstract Background Measurement-based care (MBC) is an effective tool in the delivery of evidence-based practices (EBPs). …”
Get full text

Reviews and syntheses: Current perspectives on biosphere research 2024–2025 – eight findings from ecology, sociology, and economics by F. J. Bohn, F. J. Bohn, A. Bastos, R. Martin, A. Rammig, N. S. Koh, G. B. Sioen, G. B. Sioen, B. Buscher, L. Carver, F. DeClerck, M. Drupp, M. Drupp, R. Fletcher, M. Forrest, A. Gasparatos, A. Godoy-Faúndez, G. Hagedorn, M. C. Hänsel, J. Hetzer, T. Hickler, T. Hickler, C. B. Krug, S. Koot, S. Koot, X. Li, A. Luers, S. Matevich, H. D. Matthews, I. C. Meier, M. Migliavacca, A. Mohamed, S. O, D. Obura, B. Orlove, R. Orth, L. Pereira, M. Reichstein, L. Thakholi, P. H. Verburg, Y. Yoshida

“…Our focus is on the interactions between climate, biosphere, and society and on strategies to sustain, restore, or promote ecosystems and their services. …”
Get full text

Uptake of DU145 and LNCaP prostate cancer cell line derived extracellular vesicles is inversely correlated with blood–brain barrier integrity in vitro by Ana Špilak, Adrián Klepe, Sophia Theresa Kriwanek, Heinz-Peter Friedl, Andreas Brachner, Christa Nöhammer, Winfried Neuhaus

“…This study investigated the interaction and effects of sEVs derived from low (LNCaP) and moderately metastatic (DU145) prostate cancer (PCa) cell lines with the human brain endothelial cell line hCMEC/D3. …”
Get full text

Targeting PRMT1-mediated methylation of TAF15 to protect against myocardial infarction by inhibiting ferroptosis via the GPX4/NRF2 pathway by Guanshen Huang, Liwei He, Bishan Liang, Mingjian Gao, Jianming Huang, Hao Xia, Xinyu Li, Hai Li, Yunjun Ruan

“…Methods Bioinformatics analysis of gene expression datasets was conducted to identify differentially expressed genes in AMI samples. …”
Get full text

A Chimeric Peptide Derived from a Bacterial Effector Protein Attenuates TLR-2/4-Mediated Production of Pro-Inflammatory Cytokines and Enhances the Cellular Availability of Gentamic... by Nandi BR, Patra B, Radhakrishnan GK

“…A chimeric peptide, TB4-BBL2, was then generated and evaluated for cellular uptake, interaction with TLR adaptors, and functional activities. …”
Get full text

A study on early diagnosis for fracture non-union prediction using deep learning and bone morphometric parameters by Hui Yu, Qiyue Mu, Zhi Wang, Yu Guo, Jing Zhao, Guangpu Wang, Qingsong Wang, Xianghong Meng, Xiaoman Dong, Shuo Wang, Jinglai Sun

Get full text

Preparation and characterization of the PLA: GA: ZnO nanofibers-based drug delivery system by Ghadeer Ihsan Ali, Salih Abbas Habeeb

“…The statistical analysis of all samples (P < 0.05).…”
Get full text

Ecological assessment of forest management approaches to develop resilient forests in the face of global change in Central Europe by Franka Huth, Alexander Tischer, Petia Nikolova, Heike Feldhaar, Alexandra Wehnert, Lisa Hülsmann, Jürgen Bauhus, Katrin Heer, Juliane Vogt, Christian Ammer, Uta Berger, Markus Bernhardt-Römermann, Manuela Böhme, Harald Bugmann, Jörn Buse, Laura Demant, Inken Dörfler, Jörg Ewald, Eike Feldmann, Andreas Fichtner, Martin M. Gossner, Thorsten E.E. Grams, Karl-Heinz Häberle, Jonas Hagge, Henrik Hartmann, Sven Herzog, Ansgar Kahmen, Ulrich Kohnle, Doris Krabel, Klara Krämer-Klement, Jürgen Kreyling, Michael Manthey, Karl Mellert, Peter Meyer, Andreas Mölder, Lena Muffler-Weigel, Bettina Ohse, Lars Opgenoorth, Boris Rewald, Andreas Rothe, Nadine Ruehr, Tobias Scharnweber, Michael Scherer-Lorenzen, Jonas Schmeddes, Joachim Schmerbeck, Markus Schmidt, Dominik Seidel, Frank M. Thomas, Malin Tiebel, Goddert von Oheimb, Sven Wagner, Robert Weigel, Martin Wilmking, Christian Zang, Bernhard Schuldt

Get full text

ST6GALNAC1-mediated sialylation in uterine endometrial epithelium facilitates the epithelium-embryo attachment by Xinyue Dong, Hao Wang, Jinxuan Cai, Yichun Wang, Dezhi Chai, Zichen Sun, Jie Chen, Mengxia Li, Tianxia Xiao, Chunhua Shan, Jian V. Zhang, Ming Yu

“…Introduction: Embryo implantation requires synergistic interaction between the embryo and the receptive endometrium. …”
Get full text

Associations of exposure to acrylamide and glycidamide with psoriasis among adults: Findings from a population-based study by Rui Ma, Nan Yang, Hao Mei, Yu Zhuang, Yu Wang, Yuanyuan Wang, Xin Wang, Yuling Shi

“…HbGA exposure was negatively associated with HDL and vitamin B12. Interaction analyses indicated that higher levels of serum HDL, folate, vitamin B12, and peripheral white blood cell and monocyte counts attenuated the detrimental effects of HbGA exposure on psoriasis risk. …”
Get full text

Network Pharmacology Approaches to Myocardial Infarction Reperfusion Injury: Exploring Mechanisms, Pathophysiology, and Novel Therapies by Joy Das, Ashok Kumar Sah, Ranjay Kumar Choudhary, Rabab H. Elshaikh, Utpal Bhui, Shreya Chowdhury, Anass M. Abbas, Manar G. Shalabi, Nadeem Ahmad Siddique, Raji Rubayyi Alshammari, Navjyot Trivedi, Khoula Salim Ali Buwaiqi, Said Al Ghenaimi, Pranav Kumar Prabhakar

“…Ultimately, this work aims to support the development of innovative and effective interventions for improving outcomes in patients with myocardial infarction.…”
Get full text

Balancing selection at a wing pattern locus is associated with major shifts in genome-wide patterns of diversity and gene flow by Rodríguez de Cara, María Ángeles, Jay, Paul, Rougemont, Quentin, Chouteau, Mathieu, Whibley, Annabel, Huber, Barbara, Piron-Prunier, Florence, Ramos, Renato Rogner, Freitas, André V. L., Salazar, Camilo, Silva-Brandão, Karina Lucas, Torres, Tatiana Teixeira, Joron, Mathieu

Get full text

Field Inoculation of <i>Pleurotus tuoliensis</i> in Natural Habitat Promotes Microbial Communities That Enhance Its Growth by Ying Luo, Hanbing Liu, Wenjie Jia, Nuerziya Yalimaimaiti, Qi Zhu, Peisong Jia, Yilin Huang, Wenting Shi, Chunhua Sun, Jianhua Guan

“…This study offers new insights into conserving wild edible fungi and their interactions with soil microbiota.…”
Get full text

Investigating The Performance Of Local And Indigenous Businesses In Times Of Economic Recession With Emphasis On Developing The Capabilities Of Cooperatives In Sistan And Baluchest... by Ali Asghar Tabavar, Abdoulnaser Derakhshan, Sahar Arefi

“…This test evaluated the effects of the variables in the long term and also examined the reaction of the variables to the shock of the periods of economic recession. …”
Get full text

Similar Instances Reuse Based Numerical Control Process Decision Method for Prismatic Parts by Changhong XU, Shusheng ZHANG, Jiachen LIANG, Rui HUANG, Rong BIAN

“…The simulation result shows no overcut or interference occurs, and the dimensional accuracy satisfies the quality requirements of the part. Detailed analysis of tool paths for a subpart is implemented to confirm the approach’s effectiveness. …”
Get full text

Processing demands modulate the activities and functional connectivity patterns of the posterior (VWFA-1) and anterior (VWFA-2) VWFA by Aqian Li, Chuansheng Chen, Xiaoyan Wu, Yuan Feng, Jingyu Yang, Xiaoxue Feng, Rui Hu, Leilei Mei

“…Activation analysis revealed that the VWFA-2 showed higher activation for the verbal task than the non-verbal task, while there were no activation differences in the VWFA-1 after controlling for the stimulus driven effects. …”
Get full text

Evolving Cultural Experience of Historical Places: From Livability to Visibility (A Case Study of Naqsh-e Jahan Square in Isfahan) by Seyed Mahdi Etemadifard, Amirmohammad Niroumand

“…However, the changes observed in the rhythm and quality of presence within Naqsh-e Jahan Square in a two-way interaction with the subjects present had led to further transformations in relation to the city and even national elements.Whereas the visual beauty of the square was previously effective in creating and sustaining other meanings, this research suggested that the possibilities of the square were now arranged primarily to enable an appropriate visual experience. …”
Get full text