Personalized Support in Hereditary Breast and Ovarian Cancer After Genetic Counseling by the Chatbot-Based GENIE Mobile App: Proof-of-Concept Wizard of Oz Study by Dominik Wolff, Thomas Kupka, Chiara Reichert, Nils Ammon, Steffen Oeltze-Jafra, Beate Vajen

“…The evaluation was based on their interaction with GENIE, which was personalized using the details of a fictitious patient. …”
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Transcription factor networks and novel immune biomarkers reveal key prognostic and therapeutic insights in ovarian cancer by Aiqin Zhao, Sufang Zhou, Xiaoyi Yang, Haiying Lu, Dan Zou, Xuan Zhang, Li Liu

“…The risk model is an accurate method for forecasting the effectiveness of immunotherapies, clinicopathological characteristics, and survival. …”
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THE FIRST RESULTS OF STUDIES OF TEMPORARY VARIATIONS IN SOILRADON ACTIVITY OF FAULTS IN WESTERN PRIBAIKALIE by К. Zh. Seminsky, А. А. Bobrov

“…Radon exhalation increases and decreases according to periodic variations in atmospheric pressure, which, in additional to ‘pumping’ effects, may lead to opening/closure of pores and cracks in the rocks. …”
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Identification of Bacterial Oligopeptidase B Inhibitors from Microbial Natural Products: Molecular Insights, Docking Studies, MD Simulations, and ADMET Predictions by Malik Suliman Mohamed, Tilal Elsaman, Magdi Awadalla Mohamed, Eyman Mohamed Eltayib, Abualgasim Elgaili Abdalla, Mona Timan Idriss

“…<b>Background/Objectives:</b> The increasing threat of antibiotic resistance and the declining efficiency of traditional drug discovery pipelines highlight the urgent need for novel drug targets and effective enzyme inhibitors against infectious diseases. …”
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Simulation Study on the Spatiotemporal Difference of Complex Neurodynamics between P3a and P3b by Xin Wei, Xiaoli Ni, Junye Liu, Haiyang Lang, Rui Zhao, Tian Dai, Wei Qin, Wei Jia, Peng Fang

“…It is just that the modulation effects of the two processing mechanisms are different in different tasks. …”
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Combination of Adherence to a Traditional Mediterranean Diet and Ultra-Processed Food Consumption in Relation to All-Cause and Cardiovascular Mortality: Prospective Findings from t... by Marialaura Bonaccio, Augusto Di Castelnuovo, Simona Costanzo, Emilia Ruggiero, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello

“…Results: In multivariable-adjusted analysis controlled for known risk factors, compared to the ‘low MD and high UPF’ combination, taken as reference, the ‘high MD and low UPF’ combination had a significant 24% lower rate of all-cause mortality (Hazard ratio = 0.76; 95% CI 0.67–0.86). …”
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Digital mapping of soil erodibility factor in response to land use change using machine learning models by Wudu Abiye, Orhan Dengiz

“…The superior performance of ANN is attributed to its ability to model complex, non-linear interactions among variables influencing soil erodibility. …”
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Creation of a Safe Educational Environment for Ukrainian Youth During War Conditions by Natalia Tverdokhliebova, Nataliіa Yevtushenko

“…In so doing, we seek to ensure the effective educational integration of Ukrainian youth. …”
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Influence of the Un Formation Process to the Establishment of the XX Century World Order by Dmitry Guennadievich Novik

“…This article presents a review and analysis of discussion of several questions that gave rise for some deep controversies during the United Nations Conference on International Organization. …”
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Self-management dilemmas and influencing factors of patients during the waiting period for heart transplantation in China based on the social ecosystem: a qualitative study by Juan Chen, Fei Li, Shan-Shan Liu, Xiao-Min Zhang, Yu-Hong Chen, Si-Yu Liu

“…At the macro level, systemic challenges such as the unequal distribution of medical resources and the absence of a comprehensive long-term follow-up mechanism were identified as significant barriers to effective patient management.Conclusion The dynamic interaction among the micro, meso and macro systems significantly influenced patients’ motivation and capacity for self-management, thereby ultimately affecting the progression of their disease and their overall quality of life. …”
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Psychiatric Outcomes in Patients with Trigeminal Neuralgia Treated with Anticonvulsants with or without Antidepressants: A Retrospective Cohort Study Using TriNetX by Ashley Deng, Eduardo Espiridion

“…In TN, anticonvulsants are often prescribed to address pain, while antidepressants are prescribed to address psychiatric side effects of the chronic craniofacial pain. However, interaction between antidepressants and anticonvulsants are complicated and may influence the pharmacokinetics and pharmacodynamics of each other. …”
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Sex differences in CXCL4‐mediated lung damage in the bleomycin‐induced systemic sclerosis mice model by Yi'an Tian, Jingyan Li, Bingrui Yu, Yu Chen, Tianping Bao, Yuhong Li

“…In addition, immunofluorescence double staining detected the coexpression of S100 calcium‐binding protein A8 and matrix metalloproteinase 7. Two‐way analysis of variance was used to examine the independent effects of sex, CXCL4, and their interactions. …”
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Innovative engineering training in a competitive educational environment by N. I. Naumkin, N. N. Shekshaeva, E. V. Zabrodina

“…In the course of the research, a competitive educational environment was created as a system of interacting subjects and objects of educational activity, which has a multicomponent structure. …”
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CRISPR/Cas9 screening identifies SUV39H2 as a key regulator of oHSV-1 resistance in oral squamous cell carcinoma by Manman Qiu, Qicheng Zhang, Rui Li, Rongrong Wei, Jiawei Zhao, Juan Tan, Hongkai Zhang, Wentao Qiao

“…The inhibitor OTS186935 targeting SUV39H2 was administered to evaluate its effects on viral replication both in vitro and in vivo. …”
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Optimizing hybrid network topologies in communication networks through irregularity strength by Syed Aqib Abbas Naqvi, Faraha Ashraf, Ali Ovais, Muhammad Waheed Rasheed, Amir Asif, Abdu Alameri

“…Abstract Graph theory has emerged as an influential tool for communication network design and analysis, especially for designing hybrid network topologies for local area networks (LANs). …”
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Bulk and single-cell RNA sequencing identify prognostic signatures related to FGFBP2+ NK cell in hepatocellular carcinoma by Yinbing Wu, Huanjun Peng, Guangkang Chen, Yinuo Tu, Xinpei Yu

“…Pseudo-time trajectory analysis of FGFBP2+ NK cell revealed two differential expression gene clusters. …”
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Perinatal Women’s Perception of Maternal Health Information Quality on Digital Media: Scoping Review by Bowen Li, Ningning Jin, Yingli Wang, Xiaoni Hou, Jing Meng, Yihong Zhang

“…Understanding perinatal women’s perceptions of information quality is essential for enhancing the effectiveness of information services. ObjectiveThis review aims to (1) identify the key features that perinatal women focus on when perceiving the quality of maternal health information on digital media and (2) summarize the quality issues with maternal health information on digital media that perinatal women have reported. …”
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Genetic determinants of silver nanoparticle resistance and the impact of gamma irradiation on nanoparticle stability by Amira M. Mahfouz, Walaa A. Eraqi, Hala Nour El Din El Hifnawi, Alaa El Din Shawky, Reham Samir, Mohamed A. Ramadan

“…Therefore, there is an urgent need for greater knowledge regarding the effects of improper and excessive use of these medications. …”
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Integrating network pharmacology and experimental validation to explore the mechanism of action of BushenQiangxin Formula for the treatment of chronic heart failure by Jinhua Pang, Jiejun Hou, Jinyi Chen, Wenchu Zhao, Tiantian Tang, Taotao Li, Ding Liu, Jinkai Li, Xuan Wang

“…The enzyme-linked immunosorbent assay and immunohistochemistry showed that BSQX could effectively reduce the levels of IL-17, IL-6, cTnI, and NF-KB in chronic rats. …”
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Impact of Digital Health on Patient-Provider Relationships in Respiratory Secondary Care Based on Qualitative and Quantitative Evidence: Systematic Review by Michaela Senek, David Drummond, Hilary Pinnock, Kjeld Hansen, Anshu Ankolekar, Úna O'Connor, Apolline Gonsard, Oleksandr Mazulov, Katherina Bernadette Sreter, Christina Thornton, Pippa Powell

“…ConclusionsDigital health technology can either strengthen or weaken patient-provider relationships in respiratory care, with effects impacted by adoption factors, confidence in technology, connection, and patient empowerment. …”
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