Differences in the Microbial Composition and Function of the <i>Arundo donax</i> Rhizosphere Under Different Cultivation Conditions by Fan Yang, Miaomiao Liu, Xin Wang, Yuting Hong, Qiuju Yao, Xiaoke Chang, Gongyao Shi, Weiwei Chen, Baoming Tian, Abeer Hegazy

“…To complement the metagenomic study of the <i>Arundo donax</i> rhizosphere, here, an amplicon-based metagenomic survey of bacteria and fungi was selected as a practical approach to analyzing the abundance, diversity index, and community structure of rhizosphere bacteria and fungi, as well as to study the effects of different cultivation methods on rhizosphere microbial diversity. …”
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InsNet-CRAFTY v1.0: integrating institutional network dynamics powered by large language models with land use change simulation by Y. Zeng, C. Brown, C. Brown, M. Byari, J. Raymond, T. Schmitt, M. Rounsevell, M. Rounsevell, M. Rounsevell

“…<p>To foster sustainable land use and management, it is crucial – but challenging – to enhance our understanding of how policy interventions influence decision-making actors and how these interactions can be effectively modelled. Key challenges include endowing modelled actors with autonomy, accurately representing their relational network structures, and managing the often unstructured information exchange among them. …”
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NeuroTutor: Neural Decoding of Student Engagement During Virtual and Robotic Tutoring by Shahd Elgammal, Shaymaa Alsereidi, Mahra Almansoori, Shamma Alblooshi, Abdelhadi Hireche, Abdelkader Nasreddine Belkacem

“…A transformer-based binary classifier was employed to evaluate the effectiveness of these characteristics in classifying EEG data collected during interactions with both types of tutors. …”
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Discovery of Specific Inhibitors for Intestinal E. coli  β-Glucuronidase through In Silico Virtual Screening by Ta-Chun Cheng, Kuo-Hsiang Chuang, Steve R. Roffler, Kai-Wen Cheng, Yu-Lin Leu, Chih-Hung Chuang, Chien-Chaio Huang, Chien-Han Kao, Yuan-Chin Hsieh, Long-Sen Chang, Tian-Lu Cheng, Chien-Shu Chen

“…Furthermore, the molecular docking analysis indicates that compound 4041 has two hydrophobic contacts to residues L361 and I363 in the bacterial loop, but 7145 has one contact to L361. …”
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Phenotypic stability and flowering tolerance in intermediate photoperiod onion cultivars in the Bolivian Altiplano by Gonzalo Quispe Choque, Irene Gutiérrez Limachi, Ariel Santivañez Aguilar, Nancy Huanca Alanoca

“…The results indicated that the LP-Altiplano line was the most stable in terms of yield at different locations (bi =1.13, S2di=26.93, R2=.56, ri2=24.63, Wi=125.74). From the main effects of genotype and genotype-environment interaction biplots, the lines with the best yield were Perilla (35.0 t h-1) and LP-Altiplano (34.8 t h-1), showing very stable yield and developed bulbs of shape and size in more than 90 % of the plants evaluated in the different locations. …”
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TRAF3IP3 Induces ER Stress‐Mediated Apoptosis with Protective Autophagy to Inhibit Lung Adenocarcinoma Proliferation by Guang Zhao, Jun Qi, Fang Li, Haotian Ma, Rui Wang, Xiuyi Yu, Yufei Wang, Sida Qin, Jie Wu, Chen Huang, Hong Ren, Boxiang Zhang

“…Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. …”
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IMB-XMA0038, a new inhibitor targeting aspartate-semialdehyde dehydrogenase of Mycobacterium tuberculosis by Xiao Wang, Ruifang Yang, Sihan Liu, Yan Guan, Chunling Xiao, Chuanyou Li, Jianzhou Meng, Yu Pang, Yishuang Liu

“…IMB-XMA0038 was identified as an inhibitor of MtASADH with an IC50 value of 0.59 μg/mL through screening. The interaction between IMB-XMA0038 and MtASADH was confirmed by surface plasmon resonance (SPR) assay and molecular docking analysis. …”
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Trim21 deficiency alleviates osteoporosis by inhibiting osteoclast differentiation through regulating Txnip by Ya-Chen Peng, Yong-Sheng Ye, Qin-Xiao Hu, Zhi-Quan Hao, Zhen-Yan Li, Luo-Yong Jiang, Hao-Ran Peng, Ri-Xu Liu, Zhen-Gang Zha, Huan-Tian Zhang

“…In our previous study, Trim21 deficiency was shown to exert dual effects by suppressing bone resorption and enhancing osteogenesis. …”
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Single-cell and transcriptome analyses revealed CTHRC1 a potential therapeutic target mediating invasion and tumor microenvironment in TNBC: experimental validation by Hong Wan, Hong Wan, Zichen Ling, Zichen Ling, Yuwei Xie, Yuwei Xie, Han Jiang, Han Jiang, Zhifan Ruan, Zhifan Ruan, Dashuai Yang, Xiaowei Yang, Xiaowei Yang, Jing Pei, Jing Pei

“…CTHRC1 positive CAFs exert regulatory effects within the immunosuppressive microenvironment of TNBC by modulating M2-type macrophages.…”
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Ecological security driving mechanisms and optimization of zoning in Chinese urban agglomerations: A case study of the central plains urban agglomeration by Jinyuan Zhang, Xuning Qiao, Yongju Yang, Liang Liu, Yalong Li, Shengnan Zhao

“…Spatial disparities in ecological security were relatively small, and counties with lower ecological security levels tended to show greater clustering; (2) The explanatory power of the driving factors is ranked as follows: human factors > natural factors > landscape factors. Interaction detection factors exhibit varying degrees of dual-factor or nonlinear enhancement, with the combined strength of positive effects being greater than that of negative effects; (3) The spatial distribution characteristics of ecological security zones in the CPUA align with those of ecological security conditions. …”
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Single‐cell transcriptomics reveals distinct cell response between acute and chronic pulmonary infection of Pseudomonas aeruginosa by Xueli Hu, Mingbo Wu, Teng Ma, Yige Zhang, Chaoyu Zou, Ruihuan Wang, Yongxin Zhang, Yuan Ren, Qianqian Li, Huan Liu, Heyue Li, Taolin Wang, Xiaolong Sun, Yang Yang, Miao Tang, Xuefeng Li, Jing Li, Xiang Gao, Taiwen Li, Xikun Zhou

“…Our single‐cell transcriptomic analysis revealed large‐scale comprehensive changes in immune cell composition and high variation in cell–cell interactions after acute and chronic P. aeruginosa infection. …”
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The mechanosensitive adhesion G protein-coupled receptor 133 (GPR133/ADGRD1) enhances bone formation by Juliane Lehmann, Hui Lin, Zihao Zhang, Maren Wiermann, Albert M. Ricken, Franziska Brinkmann, Jana Brendler, Christian Ullmann, Luisa Bayer, Sandra Berndt, Anja Penk, Nadine Winkler, Franz Wolfgang Hirsch, Thomas Fuhs, Josef Käs, Peng Xiao, Torsten Schöneberg, Martina Rauner, Jin-Peng Sun, Ines Liebscher

“…Current therapeutic options often come with potentially severe side effects or lack long-term efficacy, highlighting the urgent need for more effective treatments. …”
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Random Generalized Additive Logistic Forest: A Novel Ensemble Method for Robust Binary Classification by Oyebayo Ridwan Olaniran, Ali Rashash R. Alzahrani, Nada MohammedSaeed Alharbi, Asma Ahmad Alzahrani

“…Ensemble methods have proven highly effective in enhancing predictive performance by combining multiple models. …”
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Urban human-elephant conflict in Zimbabwe: a case study of the mitigation endeavour by Aliénor Scrizzi, Sébastien Le Bel, Mike La Grange, Daniel Cornélis, Cheryl Mabika, René Czudek

“…In this context, human-elephant interactions are expected to increase. Cases of urban elephant conflicts remain poorly documented, although they do exist. …”
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The Xenopyricularia zizaniicola exhibits a genome architecture distinct to the two-speed genome by Zhenyu Fang, Yuyong Li, Jianqiang Huang, Jianhong Wang, Xiwen Lian, Shuhui Lin, Zonghua Wang, Yongsheng Zhu, Huakun Zheng

“…These findings provide valuable genomic resources of family Pyriculariaceae and will facilitate future studies on host-pathogen interactions and the development of effective disease management strategies for X. zizaniicola.IMPORTANCEThe family Pyriculariaceae includes notorious pathogens that annually result in significant agricultural losses. …”
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The competition between Bidens pilosa and Setaria viridis alters soil microbial composition and soil ecological function by Qiao Li, Jianying Guo, Han Zhang, Mengxin Zhao

“…In this study, we conducted a systematic analysis focusing on B. pilosa and Setaria viridis, a common native companion plant in the invaded area. …”
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Metabolic biomarkers in patients with type 2 diabetes mellitus and heart failure with preserved ejection fraction by T. S. Sveklina, S. B. Shustov, S. N. Kolyubayeva, A. N. Kuchmin, V. A. Kozlov, E. V. Smirnova, A. V. Zharkov

“…BACKGROUND: Half of all patients with chronic heart failure (CHF) have preserved ejection fraction (CHF-nEF). The drug’s use effective for treatment of CHF with reduced ejection fraction (CHF-nFV) reduces the hospitalization incidence but does not affect the cardiovascular incidence or overall mortality in patients with CHF-nFV. …”
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Impact of Di-(2-Ethylhexyl)-Phthalate on Metabolic Syndrome: Insights from Network Toxicology and Molecular Docking and Dynamics by Chen L, Huang YL, Liu F, Huang N, Zeng DC, Zhong YB, Liao JH, Wang MY

“…The PPI network exhibited core targets, including TP53, ESR1, EGFR, TNF, and IL6. GO analysis showed entries in metabolic processes, transcriptional regulation, and redox reactions. …”
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Characteristics and Influence Mechanism of Cultural and Creative Enterprise Migration from the Amenity Perspective: A Case Study of Guangzhou by Liao Huihui, Wei Cheng, Luo Peng, Shen Jing

“…Although traditional regional factors are difficult to explain the migration characteristics and mechanisms of cultural and creative enterprises effectively, amenity theory provides a new perspective for interpreting these characteristics. …”
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Women's Lived Experiences of Sexual and Reproductive Health Challenges in Temporary Marriage: A Phenomenological Study by Fatemeh Ghasemi, Ghodratolah Khosroshahi, Amir Ghamarani, Mahnaz Noroozi

“…Identifying these challenges related to women's sexual and reproductive health is crucial for developing effective solutions. Previous research has not independently explored this issue using the phenomenological method in women with experience in temporary marriage. …”
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