Microparticles Loaded with <i>Bursera microphylla</i> A. Gray Fruit Extract with Anti-Inflammatory and Antimicrobial Activity by Víctor Alonso Reyna-Urrutia, Ramón Enrique Robles-Zepeda, Miriam Estevez, Marlen Alexis Gonzalez-Reyna, Grecia Vianney Alonso-Martínez, Juan Ramón Cáñez-Orozco, Julio César López-Romero, Heriberto Torres-Moreno

“…Gray, a plant native to northwest Mexico, has long been utilized in traditional medicine for its anti-inflammatory effects. Previous studies have highlighted the bioactivity of <i>B. microphylla</i> fruit extract. …”
Get full text

Low-Cost Titania-Hydroxyapatite (TiHAp) nanocomposites were synthesized for removal of Methylene blue under Solar and UV irradiation by Souhayla Latifi, Sanaa Saoiabi, Mohammed M. Alanazi, Omar Boukra, Anas Krime, Larbi El Hammari, Khalil Azzaoui, Belkheir Hammouti, Ghadir Hanbali, Shehdeh Jodeh, Ahmad Saoiabi, Rachid Sabbahi, Manuel Algarra, Noureddine Abidi

“…Photocatalytic degradation of MB under both solar and UV irradiation was evaluated using kinetic (pseudo-first-order and pseudo-second-order) and isotherm (Langmuir and Freundlich) models, demonstrating hydroxyapatite's key role in enhancing adsorption and facilitating effective interactions with the catalyst. Under optimized conditions, the TiHAp nanocomposite achieved 96.58 % degradation of MB at an initial concentration of 120 mg/L and retained over 95 % activity after five reuse cycles. …”
Get full text

Micheliolide Alleviates Hepatic Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via the TrxR1/2-Mediated ROS/MEK/ERK Pathway by Yi Liu, Ling Yao, Yuanyuan Liu, Yunheng Yang, Ailing Liang, Honglin He, Yao Lei, Wenfu Cao, Zhiwei Chen

“…The ROS scavenger N-acetylcysteine (NAC) attenuated MCL-induced MEK/ERK pathway activation and increased collagen type I alpha 1 (COL1A1) and fibronectin (FN) expression. Further analysis confirmed that MCL directly interacts with TrxR1 and TrxR2, leading to the inhibition of their enzymatic activities and the induction of ROS generation. …”
Get full text

Spatiotemporal evolution and driving factors of soil erosion function in a typical basin of the alpine region in the upper Yellow River by Xiaomei Kou, Qi Li, Zhen Song, Zhen Song, Qin Yu, Qin Yu, Baicheng Niu, Baicheng Niu, Baicheng Niu, Shan Wang, Shan Wang, Kaifang Mu, Kaifang Mu, Wenlin Du

“…Geodetector analysis revealed that the primary factors influencing soil erosion intensity were vegetation cover and elevation, along with their two - factor interaction. …”
Get full text

Resting state brain network segregation is associated with walking speed and working memory in older adults by Sumire D. Sato, Valay A. Shah, Tyler Fettrow, Kristina G. Hall, Grant D. Tays, Erta Cenko, Arkaprava Roy, David J. Clark, Daniel P. Ferris, Chris J. Hass, Todd M. Manini, Rachael D. Seidler

“…The interaction of left sensorimotor network segregation and age groups was associated with higher working memory function. …”
Get full text

Facilitating remote and virtual access provision by European research infrastructures – requirements, issues, and recommendations [version 2; peer review: 1 approved, 2 approved wi... by Ivan Rodero, Menattallah Elserafy, Michael RAESS, Johanna Bischof, Omran Alhaddad, Ayoub El Ghadraoui, John Dolan, Ulla Lächele, Marco Galeotti, Oguz Ozkan, Xavier Meyer, John Shepherdson, Hannele Savela, Valentina Tegas, Vanessa Spadetto, Alen Vodopijevec, Susanne Vainio, Claudia Alen Amaro, Bonnie Wolff-Boenisch, Annika Thies

“…The eRImote project collected the experiences gained in different scientific fields through targeted surveys, stakeholder workshops, expert groups discussions, and the analysis of specific use cases, with the aim of identifying good practice and presenting recommendations. …”
Get full text

Associations of lung function impairment and biological aging with mortality and cardiovascular disease incidence: findings from UK biobank participants by Jiali Chen, Cheng Wang, Pengyu Duan, Yonghong Bi, Yao Meng, Weiyu Feng, Zhehao Jin, Hangbing Li, Huihui Wang, Xiaoyan Li, Kun Zuo, Xiangcheng Zhao, Longfei Li, Yuling Xing, Lan Luo, Yang Yu, Miao Yu, Muyan Cui, Bing Zhang

“…This study aimed to investigate the mediating role of biological aging, as well as the interactions and joint effects of lung function impairment and biological aging on adverse health outcomes.MethodsA total of 349,456 UK Biobank participants (aged 40–69 years) were categorized into normal, PRISm, and AL groups based on baseline spirometric measurements. …”
Get full text

Cardiotoxicity of Chemotherapeutic Drugs (Literature Review and Clinical Case Description) by Avagimyan Ashot A., Mkrtchyan Lusine G.

“…Anthracyclines are highly effective in the treatment of solid tumors and malignant diseases of the blood system, but due to their expressed side effects on the heart, failure to use them can negatively affect the prognosis. …”
Get full text

The application of One Health concept in China and its practice and innovation in cross-sector cooperation by Yang Gao, Chengyue Li, Qingyu Zhou, Mo Hao

“…Secondly, the low two-way interaction and the lack of effective information exchange and data sharing mechanisms also limit the full implementation of the One Health concept. …”
Get full text

Application of response surface methodology (RSM) for experimental optimization in biogenic silica extraction from rice husk and straw ash by Yigezu Temesgen Zewide, Temesgen Atnafu Yemata, Adane Adugna Ayalew, Hawi Jihad Kedir, Asab Alemneh Tadesse, Asmarech Yeshaneh Fekad, Alemayehu Keflu Shibesh, Fentahun Adamu Getie, Tegen Dagnew Tessema, Tessera Alemneh Wubieneh, Wondmagegn Wonago Kululo, Muluken Tilahun Mihiret

“…A quadratic model was used to correlate the interaction effects of the independent variables for maximum silica production at the optimum process parameters by employing central composite design (CCD) with RSM. …”
Get full text

Differential Responses of Plankton Communities to Environmental Changes in the Liuqinghe Bay Estuary by Chenshi WENG, Zhixiang LI, Yingzhe WANG, Dongsheng DING, Zhengguo CUI, Keming QU, Haiyan HU, Yuqiu WEI

“…Therefore, we collected water samples from seven stations in the waters of the Liuqinghe Bay in March (spring), August (summer), and October (autumn) 2021. Redundancy analysis and Pearson's correlation analysis were used to explore the effects of environmental factors on dominant phytoplankton and zooplankton species and communities. …”
Get full text

A Novel Quinoline Inhibitor of the Canonical NF-κB Transcription Factor Pathway by Panagiotis Ntavaroukas, Konstantinos Michail, Rafaela Tsiakalidou, Eleni Stampouloglou, Katerina Tsiggene, Dimitrios Komiotis, Nikitas Georgiou, Thomas Mavromoustakos, Stella Manta, Danielle Aje, Panagiotis Michael, Barry J. Campbell, Stamatia Papoutsopoulou

“…It is therefore of vital importance to design and test new effective NF-κB inhibitors that have the potential to be utilized in clinical practice. …”
Get full text

Nanotherapeutic strategies exploiting biological traits of cancer stem cells by Hongyu Wang, Wenjing Zhang, Yun Sun, Xican Xu, Xiaoyang Chen, Kexu Zhao, Zhao Yang, Huiyu Liu

“…This review aims to provide a comprehensive framework for understanding the intersection of nanomedicine and CSC biology, contributing to more effective cancer treatment modalities.…”
Get full text

A Conformationally Driven Mechanism in n‐Type Doping of Naphthalene Diimide‐Bithiophene Copolymer by 1H‐Benzimidazoles by Simone Cimò, Ilaria Denti, Lorenzo Rossi, Marco Cassinelli, Martina Rossi, Rossella Castagna, Garrett LeCroy, Alberto Salleo, Mario Caironi, Antonino Famulari, Chiara Castiglioni, Chiara Bertarelli

“…Finally, based on the results of density functional theory simulations, the conformational modifications of the 1H‐benzimidazole dopant molecules, induced by the interaction with the P(NDI2OD‐T2), are proposed as a possible mechanism explaining the effective doping at room temperature.…”
Get full text

Chitosan based edible coating reinforced with citrus mandarin cv. terigas essential oil for shelf life extension and green mold prevention in Nagami Kumquats by Imro’ah Ikarini, Atika Hamaisa, Fitriani Fitriani, Mokhamad Nur, Fairuzan Pasyah Al Hakim, Irene Masitoh Fajrin Kurniawati, Susi Lesmayati, Unun Triasih, Anang Triwiratno, Mutia Erti Dwiastuti, Aniswatul Khamidah, Ita Yustina, Sri Widowati, Elsera Br Tarigan, Alvi Yani

“…Edible coating with 2 % chitosan minimized fruit weight loss (29.04 % on day 7) and delayed peel discoloration over 14 days of storage at room temperature. FTIR analysis confirmed the presence of intermolecular interactions between the essential oil components and the chitosan functional groups. …”
Get full text

The role of ply clustering in the impact damage of woven carbon/epoxy laminates: An experimental-numerical study by P.G. Rodríguez-Luján, R. del Cuvillo, J.M. Rodríguez-Sereno, J.A. Artero-Guerrero, D. Varas, J. Pernas-Sánchez

“…This study investigates the impact behaviour of carbon/epoxy woven laminates through experimental and numerical analysis, with particular emphasis on the effects of ply clustering. …”
Get full text

Enhanced spin polarization in GQDs/TiO2 fibers via magnetic field and oxygen vacancies for photocatalysis by Yu-Ze Sun, Jin-Hua Liu, Zhi Li, Li-Peng Qiu, Jia-Bin Song, Shuai-Jie Wang, Zhen Zhang, Ru Li, Hong-Di Zhang, Wen-Peng Han, Jun Zhang, Yun-Ze Long

Get full text

Injured tubule derived CCN1 exacerbates renal congestion-mediated acute kidney injury and fibrosis by Atsushi Minamida, Tomohiro Nakata, Ryo Kurose, Shinji Sawai, Masashi Nakamura, Minato Umehara, Hiroko Yamauchi-Sawada, Yasuto Sunahara, Yayoi Matoba, Natsuko Okuno-Ozeki, Itaru Nakamura, Kunihiro Nakai, Noriyuki Yamashita, Yuhei Kirita, Keiichi Tamagaki, Satoaki Matoba, Tetsuro Kusaba

“…We further examined the effects of CCN1 deletion in tubular epithelia and found that it reduced pFAK expression and alleviated tissue fibrosis. …”
Get full text

Intensive Glycemic Treatment Mitigates Cardiovascular and Mortality Risk Associated With Cardiac Autonomic Neuropathy in Type 2 Diabetes by Huimin Zhou, Yiquan Huang, Peihan Xie, Shaozhao Zhang, Menghui Liu, Zhenyu Xiong, Rihua Huang, Xingfeng Xu, Miaohong Li, Ziwei Zhou, Wenjing Zhang, Junqi Zhong, Yue Guo, Jingzhou Jiang, Xinxue Liao, Xiaodong Zhuang

“…Methods and Results This secondary analysis included 7866 patients from the ACCORDION (Action to Control Cardiovascular Risk in Diabetes Follow‐On) study. …”
Get full text

Isolation of phytochemicals and exploration the mechanism of Dolichandrone spathacea in the treatment of chronic bronchitis by integrating network pharmacology, molecular docking,... by Dang-Khoa Nguyen, Ta-Wei Liu, Man-Hsiu Chu, Quoc-Dung Tran Huynh, Truc-Ly Thi Duong, Thuy-Tien Thi Phan, Duyen Thi My Huynh, Yun-Han Wang, Shu-Mei Wang, Su-Jung Hsu, Ching-Kuo Lee

“…The protein–protein interaction analysis identified core targets, including TNF, AKT1, SRC, EGFR, IL2, MMP-9, HSP90AA1, and PTGS2. …”
Get full text