A Deep Learning Methodology for Screening New Natural Therapeutic Candidates for Pharmacological Cardioversion and Anticoagulation in the Treatment and Management of Atrial Fibrill... by Tim Dong, Rhys D. Llewellyn, Melanie Hezzell, Gianni D. Angelini

“…Whilst deep learning (a subtype of machine learning that uses multiple layers of artificial neural networks) methods may be useful for drug compound interaction and discovery analysis, graphical processing units (GPUs) are expensive and often required for deep learning. …”
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Evolution of microbial carbon sequestration potential in farmland soil driven by natural restoration in coal mine subsidence area by Chunming HAO, Yantang WANG, Sihai YI, Shuo LIU

“…Results indicated that natural recovery effectively restored the physicochemical properties and enzyme activities of farmland soils in coal mining subsidence areas. …”
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Evolution laws and control technology of near and far stress field in hard roof mining roadway by Jie HE, Peng CHENG, Le WU, JunPing FAN

“…Consequently, the rock surrounding the gallery’s stress control scheme for both far-field and near-field has been proven effective, providing a theoretical basis and technical reference for similar galleries.…”
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Consequences of loneliness/isolation and visitation restrictions on the mood of long-term care residents without severe dementia pre-COVID-19 and during COVID-19: a scoping review by John P Hirdes, Carrie McAiney, George A Heckman, Reem T Mulla, Brittany Kroetsch

“…Studies highlighted the importance of quality interactions with others for the well-being of LTC residents. …”
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Protective Role and Enhanced Intracellular Uptake of Curcumin in Retinal Cells Using Self-Emulsifying Drug Delivery Systems (SNEDDS) by Elide Zingale, Sebastiano Masuzzo, Tatu Lajunen, Mika Reinisalo, Jarkko Rautio, Valeria Consoli, Agata Grazia D’Amico, Luca Vanella, Rosario Pignatello

“…CUR-SNEDDS resulted in a better stability and release profile than free CUR under simulated ocular conditions. In vitro analysis of mucoadhesive properties revealed that CUR-SNEDDS, modified with a cationic lipid, demonstrated enhanced interactions with mucin, indicating the potential for improved ocular retention. …”
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Mental health in children with and without ADHD: the role of physical activity and parental nativity by David Adzrago, Saanie Sulley, Faustine Williams

“…Abstract Background Physical activity (PA) can improve mental health, including anxiety/depression, in individuals with attention-deficit/hyperactivity disorder (ADHD) with minimal side effects, unlike pharmacotherapy that can result in significant side effects. …”
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CRISPR‐Based Environmental Biosurveillance Assisted via Artificial Intelligence Design of Guide‐RNAs by Benjamín Durán‐Vinet, Jo‐Ann L. Stanton, Gert‐Jan Jeunen, Ulla vonAmmon, Jackson Treece, Xavier Pochon, Anastasija Zaiko, Neil J. Gemmell

“…CRISPR‐Cas technology also presents challenges, including searching and optimizing a guide RNA (gRNA) that is highly sensitive and has no off‐target interactions for use as an effective environmental biosurveillance tool. …”
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Exploring the therapeutic promise of Trichodesma indicum: A phytochemical, antioxidant, and in silico insights into anti-arthritis properties by Thavasiaanatham Seenivasan Shalini, Ragothaman Prathiviraj, Poomalai Senthilraja

“…Molecular docking studies further validated the therapeutic potential of these compounds, with Grossamide (PubChem ID: 101262727) demonstrating the highest binding affinity against both antibacterial (LibDock score: 173.57 shown as E. coli; GyrB) and anti-arthritic, Sphinganine (PubChem ID: 91486) exhibiting multi-interaction binding modes of (LibDock score: 169.42; 6COX) and Grossamide (LibDock score: 201.94; 8K5V) as lead candidates, Thus, T. indicum promising bioactive molecules that could serve as effective candidates for antimicrobial and anti-arthritic drug development.…”
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Instructional design of smart technology use in teacher digital educational environment by G. B. Sarzhanova, R. S. Bobesh, G. Zh. Smagulova, A. Turkel, N. B. Serikbayeva

“…The modern teacher is supposed both to adapt to and perform the professional activity within the digital setting of the educational institution and be able to design his/her own digital educational environment to transfer the educational content and organise effective “educator-learner” educational interaction. …”
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Nicotine-induced CHRNA5 activation modulates CES1 expression, impacting head and neck squamous cell carcinoma recurrence and metastasis via MEK/ERK pathway by Chen Feng, Wei Mao, Chenyang Yuan, Pin Dong, Yuying Liu

“…Cell proliferation following nicotine exposure is assessed using the CCK-8 assay, while migration and invasion are evaluated through wound healing and Transwell assays. The effects of CHRNA5 knockdown and overexpression are also investigated. …”
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ReNeuWell mental well-being app: protocol for a randomised controlled trial by Justine M Gatt, Luke A Egan

“…Data will be analysed using linear mixed models to estimate condition-by-time interaction effects on the primary and secondary outcomes, and to assess whether any such effects are themselves moderated by other key variables.Ethics and dissemination This protocol has been approved by the Human Research Ethics Committee of the University of New South Wales (reference number: HC210302). …”
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Factors Influencing Spatial Variability in Nitrogen Processing in Nitrogen-Saturated Soils by Frank S. Gilliam, Frank C.C. Somerville, Frank N.L. Lyttle, Frank M.B. Adams

“…This study examined the effects of temperature on net N mineralization and nitrification in N-saturated soils from FEF, and how these effects varied between high N-processing vs. low N-processing soils collected from two watersheds, WS3 (fertilized with [NH4]2SO4) and WS4 (untreated control). …”
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Evaluating the Elements of Vitality in Jahānshahr Walkway, Karaj City, Iran by Mina Heydari Tamrabadi, Habibollah Fasihi, Tajaddin Karami

“…The sample population consisted of 270 randomly selected walkway users. Data analysis was conducted using EXCEL software, employing an innovative model. …”
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Population dynamics and monitoring applied to decision-making by M. J. Conroy, D. C. Lee

“…Their paper provides a good example of why Bayesian analysis is particularly suited to many management problems. …”
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Platelet-derived exosomal LINC00183 facilitate colorectal cancer malignant progression driven by histone lactylation through stabilizing ENO1 by Guoqing Su, Jinghang Qian, Yi Wang, Yu Zhu, Yanyan Chen, Jingru Shen, Jiayuan Jiang, Yuepeng Cao, Nannan Wang, Xing Huang, Chengshuai Si, Xu Zhang, Peng Shao, Yongxia Ye, Yang Wang, Jun Bao, Liu Yang

“…Effective transfer of exosomal LINC00183 to human CRC cells was verified by FISH, western blotting, and RT-qPCR analyses. …”
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Article RETRACTED due to manipulation by the authors Achievement of Physical Education Learning Results Based on Gender Review and Learning Motivation on High School Students in th... by Martono Martono, Wawan Sundawan Suherman, Sigit Nugroho, Hendra Setyawan, Sulistiyono Sulistiyono, Duwi Kurnianto Pambudi, Lintang Waskita Puri, Riko Septiantoko, Yudan Hermawan, José Vicente García-Jiménez, Ratko Pavlovic, Özgür Eken, Nuridin Widya Pranoto, Arief Darmawan, Abdul Aziz Purnomo Shidiq, Muhammad Imam Rahmatullah

“…The conclusion is that motivational factors and gender significantly interact and influence students' PE learning outcomes. …”
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MODELS FOR DEVELOPMENT OF LEADERSHIP QUALITIES IN STUDENT YOUTH: DOMESTIC AND FOREIGN EXPERIENC by Lavrentieva Olena, Krupskyi Oleksandr

“…It has been found out that all existing programs for effective leader development are based on a single humanistic concept that a leader is, first of all, an individual who, guided primarily by higher spiritual needs, strives for self-realization. …”
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Possible causes, ways of development and stages of formation of atopic dermatitis in children by O.V. Gryn, O.M. Okhotnikova

“…Understanding and further study of this interaction is necessary for developing effective approaches to the prevention and treatment of atopic dermatitis.…”
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Engineering of covalent organic framework (COF) via mono-doping and co-doping for the detection of CO2 gas pollutant by John A. Agwupuye, Ekere Nwachukwu Romanus, Janefrances Ngozi Ihedioha, Ismail O. Amodu, Bassey O. Ekpong, Destiny E. Charlie, Fehintola E. Umo, Modestar Chinecherem Agwupuye, Muhammad Zeeshan

“…Upon adsorption, the studied systems showcased a non-covalent form of interaction in most cases as observed in AIM analysis. …”
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Co-design and clinician evaluation of resources to address weight stigma in antenatal care by Briony Hill, Haimanot Hailu, Bec Jenkinson, Siarn Rakic, Taniya S. Nagpal, Jacqueline A. Boyle, Penelope Sheehan, Sarah Darlison, Helen Skouteris

“…Transcripts were analysed using descriptive thematic analysis. Results We produced a set of evidence-based resources co-designed by consumers and clinicians including a consumer video designed to elicit empathy about lived experiences of weight stigma in maternity care, images representing women with diverse body sizes for use in clinic waiting rooms, a short podcast to raise awareness of weight stigma in maternity care, and signposts for the antenatal clinic to prompt clinicians to consider weight stigma in everyday clinical interactions. …”
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