Multivalent display of VP28 on chimeric virus-like particles enhances binding to shrimp target tissues: A novel antiviral strategy against white spot syndrome virus by Somkid Jaranathummakul, Pitchanee Jariyapong, Orawan Thongsum, Supawich Boonkua, Charoonroj Chotwiwatthanakun, Monsicha Somrit, Somluk Asuvapongpatana, Attaboon Wathammawut, Wattana Weerachatyanukul

“…Inhibition assays confirmed that K5-VLP more effectively interfered with VP28 binding than peptides. …”
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Dynamic changes in orbitofrontal-hippocampal connectivity linked to cognitive map formation in humans by Yidan Qiu, Huakang Li, Yuanyuan Yang, Shuting Lin, Xiaoyu Zheng, Shuxin Jia, Ruiwang Huang

“…Generalized psychophysiological interaction (gPPI) analysis showed increased connectivity between the lOFC and MTL regions during navigation, and decreased connectivity between the mOFC and MTL regions. …”
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Patterns and drivers of water-land resources nexus in arid inland river basins of northwestern China by Lingge Wang, Wei Liu, Qi Feng, Zhenliang Yin, Rui Zhu, Meng Zhu, Jutao Zhang, Yuanyuan Xue, Zexia Chen, Xuejiao Li

“…Furthermore, interactions between natural and socio-economic factors exerted stronger effects on WLNI variations than that of each individual factor, highlighting the importance of interactions between natural factors and human activities in altering water-land resources nexus in arid inland basins.…”
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Global distribution prediction and ecological conservation of basking shark (Cetorhinus maximus) under integrated impacts by Runlong Sun, Kaiyu Liu, Wenhao Huang, Xiao Wang, Hongfei Zhuang, Zongling Wang, Zhaohui Zhang, Linlin Zhao

“…Ecological corridor analysis identifies critical migratory pathways and pinch points, emphasizing the importance of incorporating the effects of climate change and human activities in the formulation of conservation strategies. …”
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Medicinal plants for the treatment and prevention of post-menopausal obesity: a review by Jing Liu, Reshmi Akter, Esrat Jahan Rupa, Hoang Van-An, Jinfeng Li, Deok Chun Yang, Dong Uk Yang, Muhammad Awais, Jong-Hoon Kim

“…Drawing from both traditional ethnobotanical knowledge and emerging scientific evidence, these compounds may offer a naturally derived strategy that could carry fewer adverse effects. Nevertheless, current findings are preliminary, and more rigorous, large-scale clinical studies are necessary to better understand their efficacy, determine appropriate dosing, and assess possible interactions with conventional therapies.…”
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Optimal vaccination model of airborne infection under variable humidity and demographic heterogeneity for hybrid fractional operator technique by Saima Rashid, Ilyas Ali, Nida Fatima, Tehreem Fatima, Fekadu Tesgera Agam, Sayed K. Elagan

“…This study proposes the dynamics of the influenza epidemic in the province of Madrid, Spain, with an emphasis on the effects of control employing actual data. The main challenge is accurately estimating the virus’s rate of transmission and assessing the effectiveness of vaccination campaigns. …”
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Cross-feeding-based rational design of a probiotic combination of Bacterides xylanisolvens and Clostridium butyricum therapy for metabolic diseases by Shanshan Qiao, Tao Wang, Jingzu Sun, Junjie Han, Huanqin Dai, Mengxuan Du, Lan Yang, Chun-Jun Guo, Chang Liu, Shuang-Jiang Liu, Hongwei Liu

“…Moreover, the two-strain combinations more effectively restored gut microbial functions by reducing disease-associated pathways and opportunistic pathogen abundance. …”
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Versatile machine learning algorithms for FTIR spectroscopy: differentiating crosslinked and non-crosslinked gelatin samples by Juliana Rincón-López, Eliana Álvarez-Valdés, Daniela Velez-Arango, Estefanía Rojas Zuleta, Leidy Yuliana Vargas Soto, Liliana Lellesch, Victor Alonso García Londoño, Milton Rosero-Moreano, Gonzalo Taborda-Ocampo

“…FTIR analysis, being rapid, efficient, non-destructive and adaptable for in-line operations, has potential for early warning systems in cross-linking processes to avoid further denaturation of gelatin.…”
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Structural insights and clinical advances in small-molecule inhibitors targeting TGF-β receptor I by Carlota Leonardo-Sousa, Rodrigo Barriga, Helena F. Florindo, Rita C. Acúrcio, Rita C. Guedes

“…We provide a detailed analysis of the structural biology of TGF-βRI, highlighting key binding interactions and structural insights derived from high-resolution X-ray crystal structures. …”
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Synthesis of piperazine-based benzimidazole derivatives as potent urease inhibitors and molecular docking studies by Delaram Shahriarynejad, Navid Dastyafteh, Fouzia Naz, Meysam Talebi, Sajedeh Safapoor, Seyedeh Niloufar Ghafouri, Homa Azizian, Maryam Mohammadi-Khanaposhtani, Bagher Larijani, Mehdi Asadi, Massoud Amanlou, Mohammad Mahdavi, Khalid Mohammed Khan

“…These results were further verified by molecular docking analysis, which indicated favorable binding energies and interactions of the compounds with the urease active site. …”
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Digital transformation of modern corporation management tools: the current state and development paths by V. A. Laptev, S. Yu. Chucha, D. R. Feyzrakhmanova

“…The authors came to the conclusion that the main direction of improving corporate legislation in the context of digitalization is currently the creation and provision of conditions for effective interaction between corporate actors and persons directly associated with them in the digital environment.…”
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UBE2J1 is identified as a novel plasma cell-related gene involved in the prognosis of high-grade serous ovarian cancer by Yunjie Tian, Ruoyu Dong, Yingxia Guan, Ying Wang, Wei Zhao, Jun Zhang, Shan Kang

“…Methods We utilized single-cell sequencing data from the Gene Expression Omnibus (GEO) database to identify key immune cell types within HGSOC tissues and to extract related markers via the Seurat package. The effects of immune cell markers on prognosis were analyzed via univariate Cox regression, least absolute shrinkage and selection operator (LASSO) and gene set variation analysis (GSVA) of bulk sequencing data from The Cancer Genome Atlas (TCGA)-HGSOC cohort. …”
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THE MORAL AND ETHICAL POTENTIAL OF A FUTURE TEACHER’S PERSONALITY – THE FOUNDATION FOR THE PRODUCTIVITY OF THEIR PROFESSIONAL TRAINING by Krasiuk Iryna

“…The study operated methods of analysis, generalisation, and specification of theoretical positions and the results of empirical research on forming the moral and ethical potential of future teachers in university education conditions. …”
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Training and Assessing Teamwork in Interprofessional Virtual Reality–Based Simulation Using the TeamSTEPPS Framework: Protocol for Randomized Pre-Post Intervention Study by Marie Lehmann, Jan Mikulasch, Horst Poimann, Joy Backhaus, Sarah König, Tobias Mühling

“… BackgroundInterprofessional teamwork is essential for patient outcomes in emergency medicine; yet, effective training in this area is scarce. Virtual reality (VR) provides a promising, resource-efficient solution for simulating emergency scenarios and facilitating interprofessional collaboration. …”
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Spatial-Temporal Changes in Ecosystem Service Value and Its Overlap with Coal Mining Intensity in the Yellow River Basin, China, During 2000–2030 by Yongjun Yang, Renjie Gong, Qinyu Wu, Fu Chen

“…The results of this study demonstrate that spatial overlap analysis is effective in identifying the hotspots and provides a foundation for developing sustainable and high-quality policies for ecologically fragile basins.…”
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Evaluating the change and trend of construction land in Changsha City based GeoSOS-FLUS model and machine learning methods by Zuopeng Zhang, Zhe Li, Zhirong Li

“…Under the farmland protection scenario, the area will grow to 1826.32 km², indicating the effectiveness of policy interventions in preserving agricultural land. …”
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Exploring the Spatio-Temporal Dynamics and Factors Influencing PM_2.5 in China’s Prefecture-Level and Above Cities by Long Chen, Yanyun Nian, Minglu Che, Chengyao Wang, Haiyuan Wang

“…However, previous studies have often obscured the spatio-temporal interactions of PM_2.5 and neglected local spatio-temporal differences in influencing factors. …”
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Speech Acts in the Written Language of Advertisements: McDonald’s Advertisements as a Case Study by Jawad El Bakri

“…The researcher can make use of that theoretical framework to identify the most frequent and different acts and their effects on target consumers. The author qualitatively and quantitatively analyzes the gathered data in the sense that he uses content analysis, as a qualitative research tool, and quantifying the frequency of certain speech acts, as a quantitative research tool. …”
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Investigating potential targets of Wulingsan in diabetic nephropathy through network pharmacology and experimental validation by Xicheng Hu, Zhen Wang, Liyan Zhang

“…BackgroundDiabetic Nephropathy (DN), a major microvascular complication of diabetes, poses challenges for current treatments to effectively delay its progression. Wulingsan (WLS), a traditional Chinese medicine formula, possesses potential for regulating water-fluid metabolism, and exhibits anti-inflammatory and antioxidant properties, yet its multi-target mechanism in treating DN remains unclear. …”
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A Novel SERS Silent-Region Signal Amplification Strategy for Ultrasensitive Detection of Cu²⁺ by Jiabin Su, Kaixin Chen, Ping Zhou, Nan Li

“…Loading a large amount of Raman molecules with signal in the silent region on the hotspots of the electromagnetic field of the SERS substrate can effectively avoid severe background noise signals and significantly improve the signal intensity, making the sensitivity and specificity of SERS detection remarkably improved. …”
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