Research progress of HGF/c-Met signaling pathway in oral squamous cell carcinoma by SHI Jiafan, GONG Lingling, SUN Mingze, LIU Lulu, ZHANG Huilin, LI Ming

“…This article aims to provide an in-depth analysis of the mechanism of action of the HGF/c-Met pathway in OSCC and its interaction with other pathways, and to review the current research status of existing therapeutic drugs. …”
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DEVELOPMENT OF CLIP THINKING OF HIGHER EDUCATION STUDENTS IN INFORMATION ENVIRONMENT by Sergey Bushuyev, Halyna Korchova, Yurii Krasylnyk, Mykola Rudenko, Borys Kozyr

“…It has been established that these and other factors force teachers to change the style, forms, methods and methods of obtaining, accumulating, processing and presenting educational information and to build effective educational practices on this basis. It was found out that information technologies, on the one hand, allow productive management of educational and cognitive activities, but also require appropriate information and technological support. …”
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Associations of microRNA Gene Polymorphisms With Salt Sensitivity, Longitudinal Blood Pressure Changes, and Hypertension Incidence in the Chinese Population by Xi Zhang, Shi Yao, Yang Wang, Chao Chu, Mingfei Du, Jianjun Mu

“…ABSTRACT MicroRNAs (miRNAs) are small endogenous RNA molecules that play an essential role in various disease processes including elevated blood pressure (BP). Although the effects of dietary salt and potassium intake on BP regulation have been established, their co‐interaction with miRNAs are still unclear. …”
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Rural women's preferences for cervical cancer screening via HPV self-sampling: a discrete choice experiment study in chidamoyo, Hurungwe District, ZimbabweAJOG Global Reports at a... by Mathias Dzobo, MSc, Tafadzwa Dzinamarira, PhD, Michael Strauss, MSc, Tivani Mashamba-Thompson, PhD

“…The stratified analysis also showed that preferences were consistent among the four subgroups. …”
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CONTEXTUAL DIMENSIONS OF M. PRODANOVYCH`S NOVELS POETICS by Nataliia L. Bilyk

“…Prodanovich`s works draws special attention to all effective indicative aspects. The context of the activity of creative figures is traditionally considered to be a separate inalienable fruitful plan of their coverage. …”
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Correlation Between miR-27a-3p Polymorphisms and Peri-Implantitis Susceptibility: A Case-Control Study by Xiaojie Gao, Yanan Ha

“…Functional enrichment analysis for target genes was performed via Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and Protein-Protein Interaction (PPI) networks. …”
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Circ_0114428 knockdown inhibits ROCK2 expression to assuage lipopolysaccharide-induced human pulmonary alveolar epithelial cell injury through miR-574-5p by Jing Zhao, Qin Zhao, Qiuxia Duan

“…LPS treatment led to decreased cell viability and proliferation and increased cell apoptosis, inflammation and oxidative stress; however, these effects were relieved after circ_0114428 knockdown. …”
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Perception and Utilization of Digital Literacy Knowledge by University Library Users from Representational Pers Perspective by SUN Zhimei, LIU Yan, LIU Wenyun, LI Ruiqin

“…First, the methodological level is mainly based on quantitative analysis, and the mining of qualitative dimensions such as details of teacher-student interaction and informal learning scenarios in digital literacy education is insufficient. …”
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The impact of using AI-powered voice-to-text technology for clinical documentation on quality of care in primary care and outpatient settings: a systematic reviewResearch in contex... by Ahmed Alboksmaty, Reham Aldakhil, Benedict W.J. Hayhoe, Hutan Ashrafian, Ara Darzi, Ana-Luisa Neves

“…All studies assessing effectiveness, patient-centredness, and efficiency (n = 9, 6, and 5, respectively) reported improvements, including faster documentation, reduced administrative burden, and enhanced patient-provider interaction. …”
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Targeting PCNA/PARP1 axis inhibits the malignant progression of hepatocellular carcinoma by Jipin Li, Jipin Li, Tao Yong, Tao Yong, Yali Chen, Tingyu Zeng, Kaifeng Zhang, Shuping Wang, Youcheng Zhang

“…The sensitivity of HCC cells to the PARP1 inhibitor Olaparib was evaluated under PCNA inhibition. Synergistic effects of AOH1160 (a PCNA inhibitor) and Olaparib were tested in vitro and in vivo using proliferation assays, DNA damage quantification, and cell cycle analysis. …”
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A Novel Two-Stage Approach for Nonlinearity Correction of Frequency-Modulated Continuous-Wave Laser Ranging Combining Data-Driven and Principle-Based Strategies by Shichang Xu, Guohui Yuan, Hongwei Zhang, Chunyu Hou, Zhirong Li, Pansong Zhang, Wenhao Xu, Zhuoran Wang

“…In this mechanism, the neural network (NN) model establishes a mapping relationship between the input and output of the real laser-modulation system, which effectively simulates this physical system and avoids the risk of trial-and-error damage. …”
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Therapeutic role of aripiprazole in cartilage defects explored through a drug repurposing approach by Jun-Ku Lee, Hyunjeong Yeo, Sujin Choi, Kyeong Mi Kim, Hannah Kim, Sung-Sahn Lee, Hyun Il Lee, Younghoon Jeong, Hyun-Ju An, Soonchul Lee

“…We utilized datasets GSE69110, GSE107649, GSE111822, and GSE116173 to identify genes associated with cartilage differentiation, employing StringTie for differential gene expression analysis and extracting drug data from the Drug-Gene Interaction database. …”
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Randomised controlled trial of a brief theory-based online intervention to reduce self-harm by Chris Keyworth, Jessica Z. Leather, Leah Quinlivan, Rory C. O’Connor, Christopher J. Armitage

“…Among people who had self-harmed in the past week at follow-up, mixed analysis of covariance revealed a significant interaction between time and condition for reflective motivation, F(1,102) = 7.08, P < 0.01, p n 2 = 0.07, such that significantly lower levels of reflective motivation were reported at follow-up in the control condition, t(57) = 2.42, P = 0.02. …”
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Evaluating the Adaptability and Sustainability of Different Straw Incorporation Strategies in Northeastern China: Impacts on Rice Yield Formation, Nitrogen Use Efficiency, and Temp... by Yuanyuan Sun, Bida Ren, Chang Liu, Bingchun Yan, Li Lin, Yanze Zhao, Hai Xu, Wenzhong Zhang, Xiaoyi Cheng, Xiaori Han

“…This study investigated the effects of straw incorporation on rice growth and the soil environment to understand the soil-crop interactions and their impact on rice yield. …”
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Participant experiences in HIV cure-directed trial with an extended analytical treatment interruption in Philadelphia, United States by Andrea Bilger, Eion Plenn, Frances K. Barg, Katharine A. Rendle, William B. Carter, Andrea Lamour-Harrington, Nora Jones, Beth Peterson, John A. Sauceda, Pablo Tebas, Karam Mounzer, David Metzger, Luis J. Montaner, Karine Dubé

“…Participants noted several significant experiences surrounding the interventions’ side effects, ATI, and returning to medication. Some participants had positive experiences with their ATI. …”
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High temperatures and microplastic enhanced inorganic phosphorus mineralization and phoD-harboring bacterial abundance in paddy soil by Muhammad Afzal, Xiyu Tan, Ma Liang Fang, Weicai Jin, Qihua Liang, Xiaolin Wang, Xiaoyuan Chen, Xiaoying Zhang, Zhiyuan Tan

“…Soil properties, gene expression, and microbial diversity were analyzed using flow injection analysis, qPCR, and high-throughput sequencing. At 29°C, MP exposure reduced soil inorganic phosphorus (Pi), dissolved organic carbon (DOC), dissolved organic nitrogen (DON), and NO₃⁻-N by 7–50 %, while increasing NH₄⁺-N by 21–26 %, with greater effects on heat-sensitive genotypes. …”
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Tumor-associated macrophages promote bladder cancer metastasis through the CCL20-CCR6 axis by Ryunosuke Nakagawa, Kouji Izumi, Kaoru Hiratsuka, Takahiro Inaba, Yoshiki Koketsu, Ren Toriumi, Shuhei Aoyama, Taiki Kamijima, Hiroshi Kano, Tomoyuki Makino, Renato Naito, Suguru Kadomoto, Hiroaki Iwamoto, Hiroshi Yaegashi, Shohei Kawaguchi, Takahiro Nohara, Kazuyoshi Shigehara, Hiroki Nakata, Wen-Jye Lin, Atsushi Mizokami

“…Additionally, CXCL1 secretion from BC cells was found to contribute to the M2-like polarization of macrophages and to enhance BC cell migration and invasion through autocrine and indirect effects. In summary, CCL20 and CXCL1 play crucial roles in the interaction between BC cells and TAMs.…”
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Sex differences in myocardial flow reserve among individuals with type 2 diabetes: insights from the DiaHeart study by Anne-Cathrine Skriver-Møller, Philip Hasbak, Ida K. B. Rasmussen, Martin B. Blond, Victor S. Wasehuus, Mats C. H. Lassen, Morten Lindhardt, Allan Kofoed-Enevoldsen, Urd L. Kielgast, Emilie H. Zobel, Jens P. Goetze, Lene Holmvang, Tor Biering-Sørensen, Peter Rossing, Andreas Kjaer, Rasmus S. Ripa, Tine W. Hansen

“…We investigated sex-dependent effects of risk factors on myocardial blood flow (MBF) and myocardial flow reserve (MFR) in individuals with type 2 diabetes without overt CVD. …”
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The CCL5/CCR5/SHP2 axis sustains Stat1 phosphorylation and activates NF-κB signaling promoting M1 macrophage polarization and exacerbating chronic prostatic inflammation by Chen Jin, Fei Zhang, Hailang Luo, Boyang Li, Xue Jiang, Christopher J. Pirozzi, Chaozhao Liang, Meng Zhang

“…In vitro, CCL5 combined with LPS stimulation amplified these effects, further promoting M1 polarization. CCL5 also sustained Stat1 activation by inhibiting its dephosphorylation through reduced interaction with SHP2, leading to prolonged inflammatory signaling. …”
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Fungal endophytes boost salt tolerance and seed quality in quinoa ecotypes along a latitudinal gradient by Roberto Miño, Roberto Miño, Gabriel I. Ballesteros, Gabriel I. Ballesteros, Karina B. Ruiz, Ian S. Acuña-Rodríguez, Ian S. Acuña-Rodríguez, Marco A. Molina-Montenegro, Marco A. Molina-Montenegro, Marco A. Molina-Montenegro

“…Remarkably, E+ plants exhibited no negative effects under non-saline conditions. These findings suggest that fungal endophytes interactions shift from neutral to beneficial under salinity, with no trade-offs under normal conditions. …”
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