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Multiple oscillators underlie circadian food anticipation in mice
Published 2025-05-01Get full text
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Status and trends in soil biodiversity – a national survey of Germany
Published 2025-06-01Get full text
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The National Regulatory Cost Burden on US aquaculture farms
Published 2025-04-01Get full text
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Impact of peer interaction on maternal health service utilization in rural northwest China
Published 2025-01-01Get full text
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Genomic and Transcriptomic Analysis to Explore the Biological Characteristics of <i>Cyclocybe chaxingu</i>
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Amentoflavone Impedes NF-&kappa;B Activation and Mediates Apoptosis Induction in Lung Cancer Cells: An in vitro and in silico exploration
Published 2025-07-01“…Chronic activation of NF-κB triggers activation of its target genes involved in promoting malignancy, metastasis, irregular proliferation of cells, and/or their resistance to programmed cell death. Amentoflavone (AMF) is a biflavonoid with intrinsic ability to modulate key signaling pathways associated with homeostatic and non-homeostatic conditions impels its exploration as therapeutic candidate against non-small cell lung carcinoma (NSCLC) A549 cells.Objective: This study investigates the anticancer potential of AMF in A549 cells, focusing on its unique dual role in NF-κB suppression and apoptosis induction, and compares its efficacy to the standard drug doxorubicin.Materials and Methods: A549 cells were treated with varying concentrations of AMF for 24 h. …”
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