Nanoparticle-Encapsulated Plant Polyphenols and Flavonoids as an Enhanced Delivery System for Anti-Acne Therapy by Ririn Puspadewi, Tiana Milanda, Muhaimin Muhaimin, Anis Yohana Chaerunisaa

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Nanotechnology in oncology: advances in biosynthesis, drug delivery, and theranostics by Mohamed M. Ammar, Rania Ali, Naira Ali Abd Elaziz, Heba Habib, Fatima M. Abbas, Mohamed Taha Yassin, Khalid Maniah, Rewan Abdelaziz

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Assessing the impact of the TB response in Taiwan – the journey towards ending TB by P.-C. Chan, C.-Y. Chiang, P.-H. Lee, H.-Y. Lo, P.-W. Chu, J.-J. Chen, S. Kato, M.C.B. Raviglione

“…During 2005-2024, Taiwan universally adopted new diagnostic tools for drug-resistant TB, shorter regimens and user-friendly platforms for reporting and case management. Nationwide policy innovations included active case finding, and TB infection (TBI) treatment. …”
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Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity by Stephane Isnard, Stephane Isnard, Tsoarello Mabanga, Tsoarello Mabanga, Léna Royston, Léna Royston, Léna Royston, Carolina A. Berini, Carolina A. Berini, Simeng Bu, Simeng Bu, Orthy Aiyana, Orthy Aiyana, Hansen Feng, Hansen Feng, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Cecilia T. Costiniuk, Cecilia T. Costiniuk, Joseph Cox, Joseph Cox, Guido Kroemer, Guido Kroemer, Guido Kroemer, Madeleine Durand, Jean-Pierre Routy, Jean-Pierre Routy, Jean-Pierre Routy, the Biobanque Québécoise de la COVID-19 (BQC-19)

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Sociocultural project as communication with the city and citizens: from the experience of the Ekaterinburg Libraries by Irina A. Cheremisinova, Olga B. Rybakova

“…Thanks to the implementation of various projects, Yekaterinburg Libraries are able not only to perform traditional functions, but also to go beyond them, becoming platforms for informal education, creative development, exchange of experience and ideas. …”
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Evaluating Virtual Game Design for Cultural Heritage Interpretation: An Exploratory Study on arkeOyun by Sevde Güner, Leman Figen Gül

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Digital strategies to promote crowdsourcing open calls for co-creating HIV interventions: a youth community-based participatory approach by Olaoluwaposi Ogunlana, Peter Kalulu, Ucheoma Nwaozuru, Olufunto A. Olusanya, Oluwayemisi T. Olaoluwa, Temitope Ojo, Titilola Gbaja-Biamila, Chiyere Arinze, Lateef Akeem, Lauren Fidelak, Chisom Obi-Jeff, Oliver C. Ezechi, Joseph D. Tucker, Joseph D. Tucker, Juliet Iwelunmor

“…The open call was promoted on social media platforms and through peer youth ambassadors. Submissions were received via various channels, including Google Forms, WhatsApp, and in-person submissions. …”
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A Review on the Stability Challenges of Advanced Biologic Therapeutics by Sruthi Sarvepalli, Shashank Reddy Pasika, Vartika Verma, Anusha Thumma, Sandeep Bolla, Pavan Kumar Nukala, Arun Butreddy, Pradeep Kumar Bolla

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Collaborative Governance in the Digital Transformation Age: A Systematic Literature Review with Bibliometric Mapping by Rio Yusri Maulana, Mitja Dečman

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Engineered Mycobacterium smegmatis expressing anti-PD-L1/IL-15 immunocytokine induces and activates specific antitumor immunity by Lin Li, Yang Yang, Baorui Liu, Jie Shen, Jie Shao, Fangcen Liu, Yi Mei, Junmeng Zhu, Xiaoxuan Sha, Rutian Li

“…Background Immune checkpoint inhibitors and cytokines have revolutionized tumor treatment but are still limited by dose-dependent toxicity and efficacy. In situ vaccine platforms based on intelligent microbes are promising therapeutic strategies that sustainably deliver drugs locally without causing severe systemic risks.Methods In this study, we have innovatively engineered a non-pathogenic, adjuvant-acting Mycobacterium smegmatis (M. smegmatis) that co-expresses a programmed cell death-ligand 1 (PD-L1) inhibitor and an interleukin-15 (IL-15) cytokine complex containing the interleukin-15 receptor alpha (IL-15Rα) sushi domain (Ms-PDL1scfv-IL15).Results We demonstrate that the fusion protein of PD-L1 inhibitor and IL-15 cytokine systemically binds mouse or human PD-L1 and maintains IL-15 stimulatory activity. …”
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Integral Assessment of the Development Level of Electronic Business in the Regions of the Volga Federal District by M. V. Bikeeva, K. V. Belash

“…The development of innovative digital technologies in Russia and in the world is widely discussed in the framework of various discussion platforms. …”
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