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Allele-specific depletion of GNAQQ209L via siRNA or an rAAV2-shRNA vector induces selective toxicity in GNAQQ209L uveal melanoma cells
Published 2025-09-01“…The most effective siRNA sequence was subsequently encoded into a short hairpin RNA (shRNA) cassette (shGNAQQ209L), expressed in a recombinant adeno-associated virus (rAAV), and the AAV2 capsid was selected for viral production upon completion of a serotype survey in UVM cells. …”
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MECHANISMS OF DESTRUCTION AND SYNTHESIS OF LIQUID MEDIA, USED IN THE FOOD INDUSTRY UNDER NON-EQUILIBRIUM CONDITIONS
Published 2019-12-01“…The possibility to control these processes for initiation of mechanical and kinetic reactions that change the structure of the medium has been demonstrated. …”
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1224
Targeted proteomics reveals compositional dynamics of 60S pre‐ribosomes after nuclear export
Published 2012-12-01“…Here, we devised a workflow that combines genetic trapping, affinity‐capture, and selected reaction monitoring mass spectrometry (SRM‐MS), to overcome this deficiency. …”
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1225
Studies on Electrochemical Deposition and Characterization of Co3o4 Films
Published 2011-01-01Get full text
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1226
Antibody of Undetermined Specificity - The Eyes Do Not See What the Mind Does Not Know: Are You Dealing with a Low Prevalence Red Blood Cell Antigens?
Published 2024-11-01“…To confirm the presence of anti-Co(b) antibodies, a selected panel cell was treated with an enzyme to enhance the expression of the Co(b+) antigen. …”
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1227
Preparation of Magnetic Molecularly Imprinted Polymers Based on Group Sensing Quenching and Their Adsorption Characteristics on Signaling Molecules
Published 2025-02-01“…Using methacrylic acid (MAA) as a functional monomer, and azobisisobutyronitrile (AIBN) as the initiator, a magnetic molecularly imprinted polymer (DMHF/SMIP) with selective adsorption for DMHF was successfully prepared via surface polymerization. …”
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1228
Solutions of a Class of Switch Dynamical Systems
Published 2025-02-01“…In this paper, a novel approach of the solutions of this class of discontinuous equations is presented. The initial value problem is restated as a differential inclusion via Filippov’s regularization, after which, via the approximate selection results, the differential inclusion is transformed into a continuous, single-valued differential equation. …”
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Classification algorithm for imbalance data of ECG based on PSOFS and TSK fuzzy system
Published 2022-09-01“…A new classification model of electrocardiogram (ECG) signal based on particle swarm optimization feature selection (PSOFS) and TSK (Takagi-Sugeno-Kang) fuzzy system was proposed, i.e., parallel ensemble fuzzy neural network based on PSOFS and TSK (PE-PT-FN), which was used for ECG prediction.Each class sample in the training set was randomly sampled, and the samples obtained by randomly sampled were added.Then, the feature selection method PSOFS was carried out independently and parallelly.In PSOFS, particles that were random initial positions represent different feature subsets and converge to the optimal positions after many iterations.Each subset had a corresponding feature subset.Several groups of TSK fuzzy neural network (TSK-FNN) were trained by each feature subset in parallel.Medical researchers could effectively find the correlation between ECG signal data and different types of disease through the interpretability of the fuzzy system and the feature subsets by the PSOFS algorithm.Experiments prove that PE-PT-FN greatly improves the macro-R to 92.35% while retaining interpretability.…”
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1230
THE ARAB'S «PEACE PLAN» ON SYRIA ON THE PAGES OF «AL-SHARQ AL-AWSAT»
Published 2021-09-01Get full text
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1231
From fledging to independence: Post-fledging movements and space use of the Crested Ibis (Nipponia nippon)
Published 2025-09-01“…We quantified changes in activity levels (based on overall dynamic body acceleration), independence timing, onset of post-fledging dispersal, habitat selection, and daily activity rhythms after independence. …”
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Non-utilization of selected newborn postnatal care and associated factors among postpartum women in East Africa: a multilevel mixed-effect analysis using the most recent DHS data 2...
Published 2025-04-01“…To address this, governments, policymakers, and all other relevant authorities must prioritize initiatives to improve the utilization of selected postnatal care in East Africa, including promoting paternal and maternal education, strengthening ANC use, enhancing media use, improving health facility delivery, and fostering long-term economic development. …”
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Comparison between 18F-DCFPyL PET/MRI-guided ultrasound fusion targeted biopsy and systematic biopsy for tumor detection and grading in selected patients: A prospective randomized...
Published 2025-01-01“…Methods: Eighty-seven selected biopsy-naive patients were randomized into two groups: TB (n=41) and systematic biopsy (control; n=46). …”
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Engineering Design for Aircraft-Based Observations of Typhoons
Published 2025-04-01“…Based on the typhoon observation practices using aircraft in China and abroad, this study proposes key considerations regarding the engineering design for aircraft-based observations of typhoons, encompassing aircraft selection, construction of support bases, airborne detection equipment, flight route planning, observation data transmission, and data application and evaluation. …”
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Multi-Objective Optimization of Speed Profile for Railway Catenary Maintenance Vehicle Operations Based on Improved Non-Dominated Sorting Genetic Algorithm III
Published 2025-04-01“…Subsequently, the enhanced selection strategy of the Non-Dominated Sorting Genetic Algorithm III (ESS-NSGA-III) algorithm is proposed to refine the mating and environmental selection processes. …”
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Assessing above ground biomass of Wunbaik Mangrove Forest in Myanmar using machine learning and remote sensing data
Published 2025-03-01“…Reference AGB information was derived from field inventory plots via an allometric equation. Initially, we tested machine learning models such as Random Forest (RF), Support Vector Machine (SVM), and Extreme Gradient Boost (XGBoost). …”
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Redundant Path Optimization in Smart Ship Software-Defined Networking and Time-Sensitive Networking Networks: An Improved Double-Dueling-Deep-Q-Networks-Based Approach
Published 2024-12-01“…Additionally, conventional end-to-end transmission algorithms that rely on single-metric and single-path selection are inadequate in fulfilling the high reliability and real-time transmission requirements essential for high-priority service data. …”
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BLF1 Affects ATP Hydrolysis Catalyzed by Native and Mutated eIF4A1 and eIF4A2 Proteins
Published 2025-05-01“…<i>Burkholderia</i> lethal factor 1 (BLF1), a toxin derived from <i>Burkholderia pseudomallei</i>, reacts with eukaryotic initiation factor (eIF) 4A to inhibit protein synthesis. eIF4A1 and eIF4A2 are involved in translation initiation and share over 90% sequence similarity. …”
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