A phase 2 study of pembrolizumab in combination with plinabulin and docetaxel in previously treated patients with metastatic non-small cell lung cancer and progressive disease (PD)... by Yan Xu, Xiaoxing Gao, Minjiang Chen, Xiaoyan Liu, Jing Zhao, Wei Zhong, Mengzhao Wang

“…Methods: In this investigator-initiated, single-arm, open-label, phase 2 trial, metastatic NSCLC pts who acquired resistance after ICI treatment were enrolled (Clinical trial information: NCT05599789). …”
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Exploring the Landscape of Standards and Guidelines in AgeTech Design and Development: Scoping Review and Thematic Analysis by Shahabeddin Abhari, Josephine McMurray, Tanveer Randhawa, Gaya Bin Noon, Thokozani Hanjahanja-Phiri, Heather McNeil, Fiona Manning, Patricia Debergue, Jennifer Teague, Plinio Pelegrini Morita

“…The synthesis of results and data analysis involved both quantitative and qualitative methods. ResultsInitially, 736 documents were identified across various databases. …”
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Structural-Functional Analysis of the Rural Housing Using Sustainable Development Approach (Case Study: in Eastern Roumeshkhan County, Kuhdasht township) by Ahmad Roumiani, Hamdollah Sojasi Qeidari, Kheirulensa Mansouri Mansouri

“…Initially, a list of 48 items in the economic, social, environmental and physical aspects of the rural housing stock in the village of East Rumshaghan was evaluated. …”
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Decoding a novel non-enzymatic protein acetylation mechanism in sperm that is essential for fertilizing potential by María Iniesta-Cuerda, Jan Nevoral, Dario Krapf, Julián Garde, Ana Josefa Soler-Valls, Marc Yeste

“…To more precisely investigate the occurrence of non-enzymatic acetylation events, acetyltransferase activity was selectively attenuated using a specific cocktail of inhibitors. …”
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Co-development of an evidence-informed, theoretically driven exercise programme for people with chronic non-specific neck pain (the EPIC-Neck programme - “Exercise Prescription Imp... by Jonathan Price, Alison Rushton, Natalie Ives, Kate Jolly, Colin Greaves

“…In Step 3, change techniques for each determinant were selected using the Theory and Techniques Tool and patient workshops. …”
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Ethnobotanical study of medicinal plants used by Lois community of Kakching district, Manipur, India by Salam Shyamchandra Singh, Laldinfeli Ralte, Hmingremhlua Sailo, Athokpam Pinokiyo, M. Roma Devi, Sandhyarani Devi Khomdram, Y. Tunginba Singh

“…Of the 5 factors studied considering selected informant based ranking, deforestation records to be the highest risk factor. …”
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Risk factors for low resilience among Grade 10 adolescents in the Gampaha district, Sri Lanka: a case-control study by Pavithra Godamunne, Shamila Manori, Pushpa Lalani Jayawardana

“…In multivariable logistic regression analysis, out of 24 independent variables entered initially into the model, only 9 were retained in the final model. …”
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A systematic scoping review of health-seeking behavior and healthcare utilization in tribal communities of odisha, india: concentration on maternal and child health by N Siva, Kasturi Mohanty, Rashmipriya Rath, Shubhasmita Mishra, Monalisa Mishra, Krishna Samal, Sasmita Das, Navaneeta Rath

“…The methodological quality of the selected studies was independently assessed by two reviewers using the JBI Quality Assessment Checklist. …”
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Prevalence, antimicrobial resistance pattern, and associated factors of Salmonella serovars among human-animal interfaces in the Amhara National Regional State, Ethiopia by Getachew Mengistu, Anwar Nuru, Baye Gelaw, Feleke Moges

“…To help reduce these infections, public health initiatives should focus on improving animal handling practices and promoting better hygiene in both the environment and personal habits through one health approach.…”
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Cartilage lesions are not the main factor influencing pain and functional impairment in early knee osteoarthritis: a multivariate analysis on intra- and extra-articular factors aff... by Luca Bianco Prevot, Alessandro Bensa, Pietro S Randelli, Giuseppe Filardo

“…Methods: The subjects were selected from the Osteoarthritis Initiative database according to the following inclusion criteria: Kellgren-Lawrence (KL) grade 0-1-2, MRI at baseline, and availability of cartilage-denuded subchondral bone values. …”
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Algunos aspectos relacionados con la sexualidad de los adolescentes del Preuniversitario Luz Palomares de Holguín by María Nereyda Ramírez Rodríguez, Nelsy Torres Pérez, Reina Len Cardet Escalona, Marisela Hernández Pérez, Bárbara Terán Guera

“…Methods: a cross- sectional study was performed in all students of eleven grade, who were selected because they were those of the intermediate level. …”
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AI-driven cybersecurity framework for software development based on the ANN-ISM paradigm by Habib Ullah Khan, Rafiq Ahmad Khan, Hathal S. Alwageed, Alaa Omran Almagrabi, Sarra Ayouni, Mohamed Maddeh

“…The proposed system provides developers and managers with valuable insights, enabling them to select security enhancements tailored to their organization's development stages. …”
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Geographic inequalities, and social-demographic determinants of reproductive, maternal and child health at sub-national levels in Kenya by Janette Karimi, Anitah Cherono, Victor Alegana, Martin Mutua, Hellen Kiarie, Rose Muthee, Marleen Temmerman, Peter Gichangi

“…Abstract Background Global initiatives have emphasized tracking indicators to monitor progress, particularly in countries with the highest maternal and child mortality. …”
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Investigation and application of data balancing and combined discriminant model in rock burst severity prediction by Shaohong Yan, Runze Liu, Yanbo Zhang, Xulong Yao, Yueqi Yang, Qi Wang, Bin Guo, Shuai Wang

“…Then, using the L2 norm to optimize the dimensionality of the indicators and supplementing with indicator importance ranking and hypothesis testing, we selected the maximum tangential stress of the surrounding rock, the ratio of the maximum tangential stress of the surrounding rock to the uniaxial compressive strength of the rock (stress coefficient), and the elastic energy index as the criteria for rock burst intensity grading. …”
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Screening of West Siberian patients with primary congenital glaucoma for CYP1B1 gene mutations by D. E. Ivanoshchuk, S. V. Mikhailova, O. G. Fenkova, E. V. Shakhtshneider, A. Z. Fursova, I. V. Bychkov, M. I. Voevoda

“…Consequently, in children with signs of increased intraocular pressure, molecular genetic analysis of the CYP1B1 gene is advisable for early diagnosis and timely initiation of PCG therapy.…”
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Development of a novel risk score for diagnosing urinary tract infections: Integrating Sysmex UF-5000i urine fluorescence flow cytometry with urinalysis. by Vo Anh Vinh Trang, Thien Tan Tri Tai Truyen, Minh Thuan Nguyen, Huu Phong Mai, Tri Cuong Phan, Son Hoang Phan, Han My Le Nguyen, Huong-Dung Thi Nguyen, Nguyen Hai Dang Le, Man Nhi Tu, Vo Thanh Vi Huynh, Hoang Tram Anh Nguyen, Dac Bao Han Ho, Ngoc Thuy Uyen Tran, Nguyen Ha Uyen Tran, Bich-Nhat Thi Le, Duc Tuan Doan, Huu Doan Pham, Truong Bao Phan, Phu Phat Pham, Tuan Vinh Nguyen, Phuc Cam Hoang Nguyen

“…Inclusion criteria were patients aged ≥18, initially diagnosed with UTI, available urinalysis, flow cytometry, and urinary culture. …”
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Prevalence and associated factors of active trachoma among children of 1 to 9 years in low-income countries of Africa: a systematic review and meta-analysis by Leykun Berhanu, Gete Berihun, Belay Desye, Abebe Kassa Geto, Chala Daba

“…As a result, it is recommended to use latrines and incorporate trachoma awareness into school curricula and community outreach initiatives.…”
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Double degree programs and education for sustainable development implementation: Experience of Ukrainian and UK universities cooperation in wartime by Iryna Skliar, Mykola Kostel’, Olena Melnyk, Kseniia Bliumska-Danko

“…This study employed semi-structured interviews. Interviewees were selected from the academic staff of five of the six Ukrainian universities involved in DDPs. …”
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Meta-analyses of mouse and human prostate single-cell transcriptomes reveal widespread epithelial plasticity in tissue regression, regeneration, and cancer by Luis Aparicio, Laura Crowley, John R. Christin, Caroline J. Laplaca, Hanina Hibshoosh, Raul Rabadan, Michael M. Shen

“…Abstract Background Despite extensive analysis, the dynamic changes in prostate epithelial cell states during tissue homeostasis as well as tumor initiation and progression have been poorly characterized. …”
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Immunization Coverage, Equity, and Access for Children with Disabilities: A Scoping Review of Challenges, Strategies, and Lessons Learned to Reduce the Number of Zero-Dose Children by Godfrey Musuka, Diego F. Cuadros, F. DeWolfe Miller, Zindoga Mukandavire, Tapiwa Dhliwayo, Patrick Gad Iradukunda, Oscar Mano, Tafadzwa Dzinamarira

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