Regorafenib versus local standard of care in patients with grade 2–3 meningioma no longer eligible for loco-regional treatments: a phase II randomized controlled trial (the MIRAGE... by Alberto Bosio, Giulia Cerretti, Marta Padovan, Paola Del Bianco, Maurizio Polano, Susanna Mandruzzato, Stefano Indraccolo, Renzo Manara, Giovanni Librizzi, Mario Caccese, Martina Corrà, Marta Maccari, Sara Lonardi, Gian Luca De Salvo, Giuseppe Lombardi

“…Abstract Background Regorafenib is an oral multi-tyrosine kinase (RTK) inhibitor. It exhibits high selectivity for VEGFR1/2/3, while also inhibiting PDGFRβ, FGFR1, and oncogenic signaling cascades involving c-RAF/RAF1 and BRAF. …”
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Clinical activity of pembrolizumab in metastatic prostate cancer with microsatellite instability high (MSI-H) detected by circulating tumor DNA by Neeraj Agarwal, Oliver Sartor, Brian Lewis, Hani Babiker, Elisa Ledet, Lesli Kiedrowski, Pedro Barata, Roberto Nussenzveig, Benjamin Gerendash, Ellen Jaeger, Whitley Hatton, Jodi Layton, Alan Bryce, Cy Stein, Philip Saylor

“…The robust activity of pembrolizumab in selected patients supports the generalized testing for MSI-H.…”
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Essential aid made fully visible: understanding the proCHW financing landscape analysing accessible donor data sources by James O’Donovan, Daniel Palazuelos, Madeleine Ballard, Mallika Raghavan, Stephanie Rapp, Ash Rogers, Carla López Castañeda, Benedicte Razafinjato, Matthew French, Cleo Baskin, Sarah Lindsay, Carey Carpenter Westgate, Laura Shellaby, Rachel Hofmann, Pauline Picho Keronyai, Niloofar Ganjian, Sonia Tiedt, Diana Nambatya Nsubuga, Jude Aidam

“…First, eight major global funders were selected through a consultative process with CHIC members, chosen based on their perceived influence, leadership in community health and scale of financial commitments. …”
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Effects of theta burst stimulation on cognitive function and characteristics of blood oxygen alterations based on near-infrared spectroscopy in chronic schizophrenia by Chunying Gao, Guangjian Li, Xiangrong Zhang, Tongbo Lu, Zhou Wang, Chenzhi Zhou, Gang Chen, Di Ma, Wenjie Wang, Xinyu Fang, Suwan Guo, Chengbao Huang, Chao Zhou

“…Methods One hundred stable chronic schizophrenia patients were selected and divided randomly into the experimental group (50 cases) and control group (50 cases). …”
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Clinical predictors of 3-month isoniazid rifapentine (3HP)-related adverse drug reactions (ADR) during tuberculosis preventive therapy (PAnDoRA-3HP study): an observational study p... by Turyahabwe Stavia, Barbara Castelnuovo, Christine Sekaggya-Wiltshire, Kelly E Dooley, Grace Banturaki, Irene Mbabazi, Ruth Mirembe Nabisere, Lucy Alinaitwe, Brian Otaalo, Florence Aber, Juliet Nampala, Rogers Owori, Josephine Bayigga, Jonathan Mayito, Eva Agnes Odongpiny Laker, Moorine Penninah Sekadde, Jotam Pasipanodya, Stella Zawedde‐Muyanja

“…ADR evaluation includes clinical assessment and liver function tests. Cases are selected from those who experience ADRs and controls from those who do not. …”
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Store‐operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease by Marilena Letizia, Yin‐Hu Wang, Ulrike Kaufmann, Lorenz Gerbeth, Annegret Sand, Max Brunkhorst, Patrick Weidner, Jörn Felix Ziegler, Chotima Böttcher, Stephan Schlickeiser, Camila Fernández, Megumi Yamashita, Kenneth Stauderman, Katherine Sun, Désirée Kunkel, Murali Prakriya, IBDome Researchers, Ashley Sanders, Britta Siegmund, Stefan Feske, Carl Weidinger

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Robot-Assisted Approach to Diabetes Care Consultations: Enhancing Patient Engagement and Identifying Therapeutic Issues by Yuya Asada, Tomomi Horiguchi, Kunimasa Yagi, Mako Komatsu, Ayaka Yamashita, Ren Ueta, Naoto Yamaaki, Mikifumi Shikida, Shuichi Nishio, Michiko Inagaki

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Scoping review of evidence-based practice guidelines for the evaluation and care of young children with developmental disabilities in LMIC settings: evidence for action by Melissa Gladstone, David Coghill, Andrew Blaikie, Tracey Smythe, Bolajoko O Olusanya, Sheffali Gulati, Agnes M Mutua, Dorcas N Magai, Brad D Berman, Angelina Kakooza Mwesige, Rebecca Claire Lusobya

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Effects of Suryanamaskara and Sheetali Pranayama on College Students Aggression: A Prospective Interventional Study by Youganjaly Mehra, Malika Sharma, Kalpana Sharma

“…Voluntary participants were initially screened using the Buss and Perry Aggression Questionnaire (AQ) and those who exhibited high aggression scores were selected for the intervention training programme. …”
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Learning Lessons for Evaluating Complexity Across the Nexus: A Meta-Evaluation of Environmental Projects by William Robert Sheate, Clare Twigger-Ross, Liza Papadopoulou, Rolands Sadauskis, Owen White, Paula Orr, Richard Eales

“…Research design: A multiple embedded case study design was adopted, selecting 23 CEP evaluation cases from across a 10-year period (2006-2016). …”
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Sustainability performance, corporate governance, and financial performance: Evidence from Poland and Central European listed companies by Joanna Błach, Elżbieta Bukalska, Bogna Kaźmierska-Jóźwiak, Anita Radman Pesa

“…Our results provide an argument for firm engagement in sustainability initiatives, as it may improve its profitability and market value. …”
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Hypertension among people living with HIV receiving dolutegravir-based antiretroviral therapy in ethiopia: a cross-sectional study by Mohammed Jemal, Desalegn Abebaw, Yabibal Tsegaye Workineh, Worku Abie Liyew, Tabarak Malik, Adane Adugna

“…Participants with a diagnosis of hypertension before DTG-based ART initiation, pregnant women, and patients who were seriously ill and unable to respond were excluded from the study. …”
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The prevalence of all types of diabetes and pre‑diabetes in the Eastern Mediterranean countries: a meta‑analysis study by Asra Moradkhani, Mobin Azami, Pardis Mohammadzadeh, Hamid Reza Baradaran, Lotfolah Saed, Kianush Asvad, Rojina Kakaei, Sorour Khateri, Farhad Moradpour, Yousef Moradi

“…Results Out of 5,238 primary studies initially screened, 186 articles were included in the meta-analysis. …”
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Mutation-Specific Cardiomyocyte Lines from Patients with Fabry Disease: A Sustainable In Vitro Model to Investigate Structure, Function, and Disease Mechanisms by Kathleen Nicholls, Andrea Wise, David Elliot, Menno ter Huurne, Maria Fuller, Sharon Ricardo

“…As a multisystemic disorder, FD initiates at the cellular level; however, the mechanism/s underlying Gb3-induced cell dysfunction remains largely unknown. …”
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Community-level mental health screening and referral using task-sharing with student volunteers in Kerala, India: a scalable model for low and middle income countries by Saju Madavanakadu Devassy, Lorane Scaria, Shyba Babu, Rajeev S.P., Lijo K.J., Amal Tom Jose, Kiran Thampi, Robin E. Gearing

“…The stability of the referral model was ensured through long term initiatives, including establishment of mental health clinics and senior daycare centres.…”
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Awareness among Women about Epidural Analgesia in Riyadh, Saudi Arabia by Sarah W. Alnosaier, Asrar A. Alahmadi, Sarah W. Alnafe, Bandar S. Alshehry

“…Participants were randomly selected, and verbal consent was obtained. The sample size was 392. …”
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Using the CIPP Model to elicit perceptions of health professions faculty and students about virtual learning by Sakineh Gerayllo, Mohammadali Vakili, Leila Jouybari, Zahra Moghadam, Ali Jafari, Alireza Heidari

“…Abstract Background The outbreak of the Coronavirus epidemic has caused a huge crisis initiating fundamental changes in education since this crisis has turned face-to-face education into virtual training. …”
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Exploring the Impact of Homophily Attitude, Physical, and Social Attractiveness on Purchase Intentions by Honya Ghasemi, Ramin Bashir Khodaparasti, Hooshmand Bagheri Garbollagh

“…Customers encounter diverse marketing initiatives that businesses swiftly promote and execute in the digital realm of social media networks, disregarding space or time constraints. …”
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INFLAMMATION's cognitive impact revealed by a novel "Line of Identity" approach. by Donald R Royall, Raymond F Palmer

“…<h4>Conclusions and relevance</h4>Our inflammation-specific psychometric classifier selects individuals with pre-specified biomarker profiles and predicts conversion to "AD" across cohorts, biofluids, and ethnicities. …”
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UNEXPECTED SPONTANEOUS REGRESSION IN CLL AFTER LETROZOLE TREATMENT: COINCIDENCE OR CONNECTION? by Ennur Ramadan, Mesut Seker, Guven Cetin

“…One month after letrozole initiation, the peripheral blood lymphocyte count was observed within normal limits (Table 1). …”
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