Cellular pattern and orbital fat involvement are possible risk factors for the failure of corticosteroids in patients with pure idiopathic orbital inflammation syndrome: lessons fr... by David Saadoun, Eric Vicaut, Valérie Touitou, Jacques Lagier, Frédéric Mouriaux, Pierre-Yves Robert, Antoine Rousseau, Nicolas Schleinitz, Jean-Marie Michot, Loic Guillevin, Matthieu Groh, Antoine Martin, Philippe Blanche, Sébastien Abad, Robin Dhote, Felix Ackermann, Boris Bienvenu, Olivier Galatoire, Sophie Coffin-Pichonnet, Pierre Aucouturier, Françoise Heran, Bertrand Vabres, Ambre La Rosa, Stéphane Tran Ba, Nahla Cucherousset, Neila Sedira, Emmanuel Héron, Aïcha Abbas, Mboup Bassirou, Isabelle Badelon, Mathieu Zmuda, Alain Ducasse, Isabelle Larré, Amélie Brabant-Viau, Jean Luc George, Jean Maalouf, Anne-Laure Fisch, Nathalie Tieulé, Juliette Delmas, Alexandre Vallon, Natahlie Massart, Marie Alexandra Alyanakian, Pierre Olivier Schischmanoff, Nabila Pizzi, Nathalie Kingue-Elessa, Jad Abou Ghantous, Solohaja-Faniaha Dimby

“…Among the 35 patients with histologically proven orbital inflammation who had previously been studied for their IgG4 immunostaining status, we selected those with a negative IgG4 status (ie, pIOIS) who received corticosteroids as single first-line treatment. …”
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Methylation-based biological age and cardiotoxicity risk in breast cancer patients treated with trastuzumab by Jamila Mammadova, Alicia Richards, Adriana Gonzalez-Torriente, Evan R. Adler, Rachel J. Cruz, Stefanie Palfi, Dae Hyun Lee, Christine Sam, Mohammed Al-Jumayli, Anders Berglund, Jong Y Park, Mohammed Alomar, Jacob K. Kresovich

“…Results Among 157 patients selected for this study, 39 (25%) experienced cardiotoxicities within one year of treatment initiation. rs776746 was inversely associated with cardiotoxicity risk (OR: 0.38, 95% CI: 0.14, 1.00, P = 0.05). …”
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Genetic Diagnosis of Adult Hemodialysis Patients With Unknown Etiology by Takuya Fujimaru, Takayasu Mori, Motoko Chiga, Shintaro Mandai, Hiroaki Kikuchi, Fumiaki Ando, Yutaro Mori, Koichiro Susa, Yuta Nakano, Takao Shoji, Yuichiro Fukudome, Naoto Inaba, Kenichiro Kitamura, Taichi Nakanishi, Keiko Uchida, Toshihiro Kimura, Teiichi Tamura, Kiyoshi Ozawa, Shinichi Uchida, Eisei Sohara

“…Of the 1164 patients who attended 4 dialysis clinics in Japan, we first selected patients who started RRT between the ages of 20 and 49 years. …”
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Hydrogen Sulfide (H₂S)-Donating Formyl Peptide Receptor 2 (FPR2) Agonists: Design, Synthesis, and Biological Evaluation in Primary Mouse Microglia Culture by Leonardo Brunetti, Fabio Francavilla, Mauro Niso, Jakub Kosma Frydrych, Ewa Trojan, Igor A. Schepetkin, Liliya N. Kirpotina, Beata Grygier, Krzysztof Łukowicz, Mark T. Quinn, Agnieszka Basta-Kaim, Enza Lacivita, Marcello Leopoldo

“…Compounds <b>7b</b> and <b>8b</b> combined potent FPR2 agonist activity, selectivity over FPR1, and the ability to release H₂S. …”
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System dynamics modeling in support of community-based decision-making to reduce opioid overdose fatalities by Turner Canty, Matthew R. Lootens, Nasim S. Sabounchi, Rachel L. Thompson, Ayanava Ganguly, Nishita Dsouza, Steve Kilburn, Jill Beloch, Gary Hirsch, Terry T.-K. Huang, Nabila El-Bassel, David W. Lounsbury

“…This paper describes the Systems Think Tank (STT), a community-engaged approach that promoted the use of systems thinking skills and system dynamics (SD) modeling for the purpose of local action planning and decision-making to select, employ, and monitor community-based strategies to prevent opioid overdose fatalities. …”
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Human microbiome-derived peptide affects the development of experimental autoimmune encephalomyelitis via molecular mimicryResearch in context by Xin Ma, Jian Zhang, Qianling Jiang, Yong-Xin Li, Guan Yang

“…Our findings offer direct evidence of how microbes can initiate the development of EAE, suggesting a potential explanation for the correlation between certain gut microorganisms and MS prevalence. …”
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School nutrition programs in Dubai: a landscape analysis by Reem AlGurg, Reem AlGurg, Nour Abu Mahfouz, Farah Otaki, Farah Otaki, Agnes Paulus, Agnes Paulus, Amar Hassan Khamis, Mohamad Alameddine

“…These 48 SNPs had varying implementation scopes and program compositions (i.e., combination of initiatives) of Parents’ Involvement, Lunch Box, Educational Curriculum, Hydration, Awareness Activities, School Canteen, and/ or Food Safety and Hygiene. …”
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Smallholder Cattle Farmers’ Knowledge, Attitudes, and Practices Toward Rabies: A Regional Survey in Kazakhstan by Nurbek Ginayatov, Zukhra Aitpayeva, Izimgali Zhubantayev, Leila Kassymbekova, Assylbek Zhanabayev, Gulmira Abulgazimova, Raikhan Arynova, Alim Bizhanov, Assiya Mussayeva, Maxat Berdikulov, Marat Aisin, Zaure Sayakova, Spandiyar Tursunkulov, Nurkuisa Rametov, Ainur Akhmadiyeva, Aigul Bulasheva, Nurgul Jussupbekova, Olzhas Yeskhojayev, Gulnara Baikadamova, Kaissar Kushaliyev, Nadezhda Burambayeva, Arman Issimov

“…This study highlights the need for targeted educational initiatives to improve rabies awareness and promote safer livestock management practices. …”
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Effect of bariatric endoscopy on liver fibrosis and steatosis and the course of NAFLD – a prospective interventional study by Adam Vašura, Evžen Machytka, Ondřej Urban, Jitka Macháčková, Lubomír Pavliska, Zdeněk Berka, Zdeněk Švagera, Marek Bužga

“…In a subset of patients with NAFLD, an inflammatory process arises in the steatotic liver, known as non-alcoholic steatohepatitis, that leads to liver fibrosis and liver cirrhosis. In selected patients with obesity, bariatric surgery, and bariatric endoscopy are important therapeutic options. …”
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Seabed Acoustic Mapping Revealing an Uncharted Habitat of Circular Depressions Along the Southeast Brazilian Outer Shelf by Ana Carolina Lavagnino, Marcos Daniel Leite, Tarcila Franco, Pedro Smith Menandro, Fernanda Vedoato Vieira, Geandré Carlos Boni, Alex Cardoso Bastos

“…Initiatives such as the United Nations Decade of Ocean Science for Sustainable Development and Seabed 2030 promote seabed mapping worldwide. …”
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Recurrence of hypoglycaemia and associated factors among neonates admitted with perinatal asphyxia in Northwest Ethiopia: multicentre, retrospective follow-up study with negative b... by Wubet Tazeb Wondie, Gezahagn Demsu Gedefaw, Asnake Tadesse Abate, Degalem Tilahun Worku, Mulugeta Endalamaw Ayenew, Temesgen Brilie Asmare, Astewil Moges Bazezew, Tsehayu Melak Siyoum, Yaregal Semanew Endeshaw

“…Presence of neonatal meningitis, delayed initiation of feeding 72 hours after birth, stage 3 hypoxic-ischaemic injury, length of hospital stay and macrosomia were the key factors associated with recurrence of hypoglycaemia.…”
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Repurposing drugs for the human dopamine transporter through WHALES descriptors-based virtual screening and bioactivity evaluation by Ding Luo, Zhou Sha, Junli Mao, Jialing Liu, Yue Zhou, Haibo Wu, Weiwei Xue

“…Subsequently, ADMETlab was employed to predict the pharmacokinetic and toxicological properties of these candidates, while induced-fit docking (IFD) was performed to estimate their binding affinities. Six compounds were selected for in vitro assessments of neurotransmitter reuptake inhibitory activities. …”
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The clinical utility and safety of biomarker-guided immunosuppression withdrawal in liver transplantation: the LIFT prospective RCT by Julien Vionnet, Rosa Miquel, Juan G Abraldes, Juan-Jose Lozano, Pablo Ruiz, Miquel Navasa, Aileen Marshall, Frederik Nevens, William Gelson, Joanna Leithead, Steven Masson, Elmar Jaeckel, Richard Taubert, Phaedra Tachtatzis, Dennis Eurich, Kenneth Simpson, Eliano Bonaccorsi-Riani, James Ferguson, Alberto Quaglia, Maria Elstad, Marc Delord, Abdel Douiri, Alberto Sánchez-Fueyo

“…Ten out of the 56 (18%) of patients who initiated immunosuppression withdrawal in Arm A achieved operational tolerance at 12 months versus 3 among the 24 patients (13%) who initiated withdrawal in Arm B. …”
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RZYMSKA GENEZA INSTYTUCJI ZAWIADOMIENIA DŁUŻNIKA O PRZELEWIE WIERZYTELNOŚCI. DENUNTIATIO Z C. 8,41,3 PR. A WYBRANE USTAWODAWSTWA WSPÓŁCZESNE by Piotr Ściślicki

“… THE ROMAN ORIGINS OF THE NOTICE TO DEBTOR OF ASSIGNMENT DENUNTIATIO IN C. 8,41,3 PR. AND SELECTED CONTEMPORARY LEGAL SYSTEMS Summary The transferability of relative rights is now commonly admitted as one of the most basic and indispensable foundations of economic turnover. …”
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Breeding of a new high-quality and mid-ripening peach cultivar Zijinyucui by XU Jianlan, SHEN Zhijun, GUO Lei, CAI Zhixiang, ZHANG Yuyan, ZHANG Binbin, ZHANG Chunhua, SONG Siyan, YU Mingliang, MA Ruijuan, DING Hui

“…The average flower bud initiation occurs at the 2.1st node, with flower buds being 1.62 times more than leaf buds. …”
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Recurrent adenoid cystic carcinoma of the left upper palate accompanied by massive maxillary hemorrhage: a case report and literature review by ZHANG Wangru, CHEN Yuanyuan, LI Zhiping, MENG Jian

“…The patient was a 36-year-old female with ACC located in the left palate, initially diagnosed at clinical stage T3N0M0 in 2013. …”
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Challenges and Strategies in Healthcare Workforce Management: A Scoping Review by Ali Mohammad Mossadeghrad, Shervin Mossavarali, Seyed Hamid Hosseini Neishabouri, Arman Khanjani, Shabnam Afraz, Alireza Jafari Azad, hoda Ghobeishipour

“…Information sources and selected methods for study:  A scoping review was conducted in August 2023 to identify the challenges faced by healthcare workers and suggest appropriate solutions. …”
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The impact of technology use for care by informal female caregivers on their well-being: a scoping review by Andrés Aparicio, María Alejandra Inostroza-Correa, Paula Miranda, Carolina Salinas, Valeria Herskovic, Camila Chackiel, Catalina Alarcón

“…Sources were screened in stages by two independent reviewers; data were extracted from selected full texts, and results were integrated into a narrative summary. …”
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Clinical outcomes of antifungal therapy on Candida pulmonary colonisation in immunocompetent patients with invasive ventilation: a systematic review and meta-analysis by Shan Su, Linqi Li, Hongzhong Yang, He-Bin Xie

“…Subgroup analysis of different treatment types indicates that the combined effect size is stable and unaffected by different treatment types including inhalation (OR: 2.32; 95% CI 0.30 to 18.09) and intravenous (OR: 0.65; 95% CI 0.13 to 3.34).Conclusion The application of antifungal treatment did not improve clinical outcomes in patients with MV. We do not suggest initiating antifungal treatment in patients with Candida pulmonary colonisation after invasive ventilation.Trial registration number International Prospective Register of Systematic Reviews, CRD42020161138.…”
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Determinants of knowledge of preconception care among healthcare providers in Ethiopia: a systematic review and meta-analysis by Biruk Beletew Abate, Gizachew Yilak, Befkad Derese Tilahun, Nimona Amena, Tegene Atamenta Kitaw, Mulat Ayele, Addis Wondmagegn Alamaw, Eyob Shitie Lake

“…Objective To assess the determinants of knowledge of preconception care (PCC) among healthcare providers in Ethiopia.Design Systematic review and meta-analysis.Data source Comprehensive literature searches were conducted in PubMed, Scopus and Health Internetwork Access to Research Initiative (HINARI) published until 20 March 2024.Eligibility criteria for selecting studies Primary studies that reported the prevalence, determinants or associated factors were included.Data extraction and analysis Three authors extracted all the relevant data using a standardised Joanna Briggs Institute data extraction format. …”
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