Successful treatment of recurrent unresectable squamous cell carcinoma of the head and neck using pembrolizumab by A. M. Mudunov, I. М. Gelfand, О. D. Ryzhova, A. A. Akhundov, М. N. Narimanov, A. V. Ignatova

“…The study objective is to report a case of successful treatment of recurrent unresectable squamous cell carcinoma of the head and neck using pembrolizumab (selective inhibitor, preventing the interaction between the programmed death receptor 1 (PD1) and its ligands PD-L1 and PD-L2).Materials and methods. …”
Get full text

Female sex worker preferences for HIV pre-exposure prophylaxis delivery in Uganda: A discrete choice experiment. by Ruth Mpirirwe, Rita Makabayi-Mugabe, Laban Muteebwa, Onesmus Kamacooko, Felix Wamono, Mayanja M Kajumba, Joan Nangendo, Fred C Semitala, Peter Kyambadde, Katumba James Davis, Joan Kalyango, Charles Karamagi, Agnes Kiragga, Mari Armstrong-Hough, Sarah E G Moor, Anne R Katahoire, Moses R Kamya, Andrew Mujugira

“…We conducted a discrete choice experiment (DCE) with female sex workers (FSWs) aged 18 and above at the Most At-Risk Population Initiative (MARPI) clinic in Kampala, Uganda, from October to November 2023. …”
Get full text

Non-invasive blood glucose monitoring using PPG signals with various deep learning models and implementation using TinyML by Mahdi Zeynali, Khalil Alipour, Bahram Tarvirdizadeh, Mohammad Ghamari

“…The selected model, after being optimized and deployed on an embedded device, achieved immediate blood glucose estimation with a processing time of just 6.4 seconds, demonstrating the method’s practical applicability. …”
Get full text

Identifying the Components and Touchpoints of Promotional Advertising from the Perspectives of Social Marketing in Organ Donation by Majid Esmaeili, Hossein Budaghi Khajeh Noubar, Hossein Gharebeiglou, Ali Shahinpour

“…A total of 83 articles were selected for inclusion in the study. Subsequently, thematic analysis was employed, focusing on components and themes influencing behavior change related to organ donation. …”
Get full text

Systematic Review with Network Meta-Analysis: Efficacy of Induction Therapy with a Second Biological Agent in Anti-TNF-Experienced Crohn’s Disease Patients by Cristiano Pagnini, Spyros I. Siakavellas, Giorgos Bamias

“…A systematic review of the literature was conducted using specific criteria for selecting relevant randomized clinical trials evaluating response to administration of secondary biological therapy in “anti-TNF-experienced” CD patients. …”
Get full text

Immunochromatographic food control tools: New developments and practical prospects by A. V. Zherdev, E. A. Zvereva, N. A. Taranova, I. V. Safenkova, N. L. Vostrikova, B. B. Dzantiev

“…Contact of the test strip with the sample being tested, initiates all further interactions and generates the recordable or visually assessable optical signal. …”
Get full text

Association between ocular bacterial carriage and follicular trachoma following mass azithromycin distribution in The Gambia. by Sarah E Burr, John D Hart, Tansy Edwards, Ignatius Baldeh, Ebrima Bojang, Emma M Harding-Esch, Martin J Holland, Thomas M Lietman, Sheila K West, David C W Mabey, Ansumana Sillah, Robin L Bailey

“…<h4>Methodology/principal findings</h4>We examined associations between clinical signs of TF and ocular colonization with four pathogens commonly found in the nasopharnyx, three years after the initiation of mass azithromycin distribution. Children aged 0 to 5 years were randomly selected from 16 Gambian communities. …”
Get full text

Monotonicity Criterion-Based Power Quality Improvement in Distributed Energy Systems with Solar PV Integration by Phani Kumar Chittala, Elanchezhian E.B, Pragaspathy Subramani, Subramanian S

“…The monotonicity criterion was applied to select optimal PV distribution, aimed at compensating for load variation and improving power quality. …”
Get full text

Cardiological Findings in Children and Adolescents Before and After Guanfacine Treatment for Attention Deficit and Hyperactivity Disorder by Bekir Yükcü, Bedia Sultan Önal, Cansu Çobanoğlu Osmanlı, Gülsüm Yitik Tonkaz, Berkan Şahin

“…<b>Conclusions:</b> Guanfacine demonstrated minor, statistically significant effects on the selected cardiac parameters without clinically meaningful changes to or adverse impacts on the novel ECG markers investigated. …”
Get full text

Expression of Vascular Endothelial Growth Factor in Uveal Melanoma by V. G. Likhvantseva, O. A. Anurova, S. E. Astakhova, M. V. Vereshchagina, V. E. Ovanesyan, E. V. Stepanova

“…VEGF’s expression in UM is cyclical. The cycle is re-initiated, apparently, by increasing cell density in tumor proliferate and the development of hypoxia zones. …”
Get full text

Comprehensive Probabilistic Analysis and Practical Implications of Rainfall Distribution in Pakistan by Fahad Haseeb, Shahid Ali, Naveed Ahmed, Nassir Alarifi, Youssef M. Youssef

“…Accurately selecting an appropriate probability distribution model is a critical challenge when predicting extreme rainfall in arid and semi-arid regions, especially in countries with diverse climatic conditions. …”
Get full text

Enhancement and evaluation for deep learning-based classification of volumetric neuroimaging with 3D-to-2D knowledge distillation by Hyemin Yoon, Do-Young Kang, Sangjin Kim

“…However, this approach, by selecting only projected 2D slices from the entire volume, reflects only partial volumetric information. …”
Get full text

Subcutaneous sumatriptan for the treatment of postcraniotomy pain (SUPS trial): protocol for a randomised double-blinded placebo controlled trial by Ana Licina, Jeremy Russell, Andrew Silvers, Xin Jin, Jason Denny

“…Both patient groups will receive a subcutaneous injection at a point where recovery-nursing staff would initiate the usual intravenous opioid analgesia as per standardised pain management protocol. …”
Get full text

RELATIONSHIP BETWEEN PERIODONTAL DISEASES AND MENTAL HEALTH: A NARRATIVE REVIEW by Mariana O. Levkiv, Pavlo Yu. Ostrovskyi, Svitlana I. Boitsaniuk

“…It was utilized 4 databases to find articles published from 2010 to November 2024. Initially, it was identified 1712 records, and after screening and applying specific inclusion and exclusion criteria, 98 articles were selected for full-text review. …”
Get full text

“Scarlet Cloak and the Forest Adventure”: a preliminary study of the impact of AI on commonly used writing tools by Barbara Bordalejo, Davide Pafumi, Frank Onuh, A. K. M. Iftekhar Khalid, Morgan Slayde Pearce, Daniel Paul O’Donnell

“…However, the use of Microsoft Bing Copilot and Writefull on our selected texts were able to eschew AI detection fairly consistently. …”
Get full text

E3 ubiquitin ligase RNF128 negatively regulates the IL-3/STAT5 signaling pathway by facilitating K27-linked polyubiquitination of IL-3Rα by Jingge Yu, Jianguo Li, Ao Shen, Zhiping Liu, Tian-Sheng He

“…IL-3 receptor α (IL-3Rα) specifically binds to IL-3 and initiates intracellular signaling, resulting in the phosphorylation of STAT5. …”
Get full text

Applicant Factors for Matching Into an Orthopaedic Foot and Ankle Fellowship by Zachary C. Lum DO, Kyle Astleford BS, Christopher Kreulen MD, Eric Giza MD

“…Background: Over the past 2 decades, various initiatives have aimed to enhance diversity in orthopaedic surgery, promoting greater racial, ethnic, and gender equity. …”
Get full text

What is the current scope of research assessing patients’ and clinicians’ perspectives on clozapine treatment? A comprehensive scoping review by Jimmi Nielsen, Erik Simonsen, Ole Jakob Storebø, Michelle Iris Jakobsen, Stephen F Austin, Julie Perrine Schaug

“…Furthermore, citation tracking of selected studies was undertaken.Eligibility criteria We included primary, empirical studies reporting clinicians’ and/or patients’ perspectives on clozapine treatment. …”
Get full text

Building consumer loyalty through green marketing: an Egyptian perspective by Amr Samir Aly, Luna Santos-Roldán, Beatriz Palacios-Florencio

“…Conducted in the Egyptian context, this quantitative study surveyed 460 randomly selected respondents using a structured questionnaire, with data analyzed through the AMOS program. …”
Get full text

Research on the Inversion Method of Dust Retention in Grassland Plant Canopies Based on UAV-Borne Hyperspectral Data by Yibo Zhao, Shaogang Lei

“…The spectral index with the highest absolute value of the correlation coefficient with the canopy dust retention is selected as the feature variable for each spectral index. …”
Get full text