Approach to Lung Transplantation in Pulmonary Arterial Hypertension: A Delphi Consensus on Behalf of the Transplant Task Force of the Pulmonary Vascular Research Institute by Nicholas A. Kolaitis, Hayley Barnes, Deborah J. Levine, Howard Castillo, Selim M. Arcasoy, Matthew Bacchetta, Luke Benvenuto, Erika Berman‐Rosenzweig, Marisa Cevasco, Caitlin T. Demarest, Celine Dewachter, Michiel E. Erasmus, Allan R. Glanville, John Granton, Shaf Keshavjee, Vikramjit Khangoora, Sheila Krishnan, Olaf Mercier, Andrea N. Miltiades, David Montani, Edward Murphy, Ivan Robbins, Franck F. Rahaghi, Sahar A. Saddoughi, Laurent Savale, Marc A. Simon, Jean‐Luc Vachiery, Corey E. Ventetuolo, Helen M. Whitford, Reda E. Girgis

“…ABSTRACT Lung transplantation is indicated for selected patients with advanced pulmonary arterial hypertension (PAH). …”
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Analyzing the Association of Social Capital and Sleep Quality of the Elderly Community by Maryam Mohammadi, Sahar Mohammadnabizadeh, Mehdi Varmaghani, Mitra Moodi, Farshad Shrifi, Matin Shirazinia, Hossein Fakhrzadeh, Moloud Payab, Masoumeh Khorashadizadeh, Shohreh Naderimagham

“…Sampling was carried out by selecting eligible participants based on a simple random entry criterion. …”
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Development of machine learning models for predicting depressive symptoms in knee osteoarthritis patients by Dan Li, Han Lu, Junhui Wu, Hongbo Chen, Meidi Shen, Beibei Tong, Wen Zeng, Weixuan Wang, Shaomei Shang

“…The China Health and Retirement Longitudinal Survey (CHARLS) data were used for model development and the Osteoarthritis Initiative (OAI) for external validation. 18 potential predictors were selected using LASSO regression. 4 machine learning models—logistic regression, decision tree, random forest, and artificial neural network—were developed. …”
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Liraglutide use in pediatric type 2 familial partial lipodystrophy caused by LMNA mutation: a case report by Youran Li, Ronghua Yu, Ting Song, Yongmei Xiao, Wuhen Xu, Ting Zhang, Xiaolu Li

“…Abstract Background Type 2 familial partial lipodystrophy (FPLD2), or Dunnigan syndrome, is a rare genetic disorder characterized by selective subcutaneous fat loss, metabolic complications, and insulin resistance due to LMNA gene mutations. …”
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Mild hypothermia attenuates hepatic ischemia-reperfusion injury by regulating FoxO1/PPARα pathway by Zhongshan Lu, Hao Chen, Anxiong Liu, Shufang Na, Wei Wang, Zibiao Zhong, Qifa Ye

“…Mechanistically, MH promoted FoxO1-PPARα interaction, enhancing PCK1 and CPT1a transcription and boosting hepatic metabolism. Selective FoxO1 inhibition by AS1842856 worsened IRI and apoptosis by reducing gluconeogenesis and FAO, MH partially mitigated this damage and promoted energy metabolism. …”
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Hormonal modulation, mitochondria and Alzheimer’s prevention: the role of GLP-1 agonists and estrogens by Fernando Lizcano, Fernando Lizcano, Fernando Lizcano, Fernando Lizcano, Daniela Sanabria, Daniela Sanabria, Eliana Aviles, Eliana Aviles

“…Ongoing clinical trials and future research must consider sex-specific factors, receptor polymorphisms, and brain-region selectivity to optimize the translational potential of this combined strategy.…”
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Managing bladder tumor with long-segment anterior urethral stricture: Perineal urethrostomy as a critical surgical solution by Hamza El Abidi, Salim Ouskri, Idriss Ziani, Reda Tariqi, Imad Boualaoui, Ahmed Ibrahimi, Hashem El Sayegh, Yassine Nouini

“…Imaging revealed a large, vascularized bladder mass with invasion into perivesical fat and left-sided hydronephrosis. TURBT was initially planned, but a long-segment anterior urethral stricture prevented endoscopic access. …”
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Effect of Cumulative Exposure on the Efficacy of Paroxetine: A Population Pharmacokinetic‐Pharmacodynamic and Machine Learning Analyses by Keiichi Shigetome, Tomoko Egashira, Tetsu Tomita, Nagisa Higa, Kazuma Iwashita, Kazuya Morita, Miki Nishimura, Tetsuya Kaneko, Hitoshi Maeda, Kazunori D. Yamada, Ayami Kajiwara‐Morita, Kentaro Oniki, Norio Yasui‐Furukori, Junji Saruwatari

“…ABSTRACT Selective serotonin reuptake inhibitors (SSRIs) are widely used in depression treatment. …”
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Experimental study on the strengthening mechanism of carbon fiber-reinforced sand powder 3D-printed rock-like materials by Lishuai Jiang, Xin He, Ye Zhao, Pimao Li, Yang Zhao, Zongke Wang, Dingrui Guo, Qi Gu

“…In this study, silica sand and furan resin were selected as printing materials, and carbon fiber at various dosages were incorporated during the preparation process. …”
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End-of-life care for people with severe and persistent mental illness and a life-limiting disease: An umbrella review by Jonas Denduyver, Johan Detraux, Justien Weydts, Marc De Hert

“…A critical appraisal of the selected reviews was performed. Data were analyzed according to the four principles of biomedical ethics. …”
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DenseIncepS115: a novel network-level fusion framework for Alzheimer's disease prediction using MRI images by Fatima Rauf, Muhammad Attique Khan, Ghassen Ben Brahim, Wardah Abrar, Areej Alasiry, Mehrez Marzougui, Seob Jeon, Yunyoung Nam

“…The proposed architecture hyperparameters are initialized using Bayesian Optimization, which impacts the better learning of the selected datasets. …”
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E3 ligase RNF128 restricts A. alternata-induced ILC2 activation and type 2 immune response in the murine lung by Chenghua Yan, Wendong Kuang, Guangqiang Ma, Feifei Guo, Liang Jin, Hongjiao Wan, Jinhua Zhu, Yongcui Liao, Haijun Tan, Liyuan Wang

“…RNF128 deficiency caused a selective increase in the number of peripheral mature ILC2s, and mice with RNF128 deficiency were more susceptible to Alternaria alternata (A. alternata) -induced allergic lung inflammation. …”
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Differential Expression of Inflammation-Related Genes in Down Syndrome Patients with or without Periodontal Disease by M. Baus-Domínguez, R. Gómez-Díaz, D. Torres-Lagares, J. R. Corcuera-Flores, J. C. Ruiz-Villandiego, G. Machuca-Portillo, J. L. Gutiérrez-Pérez, M. A. Serrera-Figallo

“…Of the 92 inflammation-related genes taken initially, four genes showed a differential expression across both groups with a p value of <0.05 from the data obtained using RNA processing of the patient sample. …”
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Aptamer-based dual-enzyme, amplification-free biosensor integrating CRISPR-Cas12a and Exo III for sensitive detection of ATP by Baolin Li, Yaxin Huang, Zixin Zhu, Min Zhong, Guangrong Li, Jinbo Liu

“…This strand displaces an activation chain, which in turn interacts with Cas12a's crRNA, initiating trans-cleavage activity that cleaves a single-stranded DNA probe to produce a fluorescent signal. …”
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Innovations in Quail Welfare: Integrating Environmental Enrichment, Nutrition and Genetic Advances for Improved Health and Productivity by O. E. Oke, K. M. Oliyide, O. A. Akosile, A. I. Oni, E. O. Adekunle, B. O. Oyebanji, O. P. Aremu, I. M. Adeoba, T. A. Eletu, J. O. Daramola

“…Results are starting to emerge from selective breeding initiatives designed to increase stress tolerance, disease resistance and environmental adaptation. …”
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A Synoptic- and Remote Sensing-based Analysis of a Severe Dust Storm Event over Central Asia by Parya Broomandi, Kaveh Mohammadpour, Dimitris G. Kaskaoutis, Aram Fathian, Sabur F. Abdullaev, Vladimir A. Maslov, Amirhossein Nikfal, Ali Jahanbakhshi, Bakhyt Aubakirova, Jong Ryeol Kim, Alfrendo Satyanaga, Alireza Rashki, Nick Middleton

“…The dust storm originated in the steppes of southern Kazakhstan by violent downdraft winds. Initially it swept over eastern parts and then the whole of Uzbekistan, reaching the Caspian Sea in the west. …”
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Genetic Variability in eIF2α Gene Is Associated with Islet β-Cell Function in the Development of Diabetes in a Chinese Han Population by Nan Gu, Xiaowei Ma, Jianwei Zhang, Mengmeng Jin, Nan Feng, Ruifen Deng, Ge Bai, Hong Zhang, Xiaohui Guo

“…Protein kinase-like endoplasmic reticulum kinase (PERK)/eukaryotic translation initiation factor 2 alpha (eIF2α) pathway mutations lead to failure of β-cell function. …”
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Identification of optimum scopes of environmental drivers for schistosome-transmitting Oncomelania hupensis using agent-based model in Dongting Lake Region, China by Junhui Huang, Jiamin Wang, Yanfeng Gong, Ning Xu, Yu Zhou, Liyun Zhu, Liang Shi, Yue Chen, Qingwu Jiang, Yibiao Zhou

“…As soil temperature increased, the snail density initially rose before declining, reaching its peak at around 21°C. …”
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An experimental study of the effect of temperature on teeth breaking efficiency based on rock mechanical properties by Dongdong Song, Mingmin He, Jian Wang, Heyi Yuan, Ke Liu, Zijie Li, Heng Yin, Jun Yan, Yingxin Yang, Zhen Liu

“…Conical teeth can be used to select the tooth shapes of bits to improve drilling efficiency. …”
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Exploring the dilemma of secondary fracture prevention in Chinese families from the experience of elderly fragility fractures: a qualitative study based on Confucian cultural backg... by Nan Tang, Lingjie Jiang, Mingxing Lei, Qingqing Su, Jie Song, Dan Kong, Xiang Cui, Yuan Gao

“…Methods A purposive sampling method was used to select 20 elderly patients with osteoporotic subsequent fractures and 10 family caregivers from a tertiary hospital in Beijing for semi-structured interviews. …”
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