Design differences and variation in results between randomised trials and non-randomised emulations: meta-analysis of RCT-DUPLICATE data by Sebastian Schneeweiss, Shirley V Wang, Rachel Heyard, Leonhard Held

“…Objective To explore how design emulation and population differences relate to variation in results between randomised controlled trials (RCT) and non-randomised real world evidence (RWE) studies, based on the RCT-DUPLICATE initiative (Randomised, Controlled Trials Duplicated Using Prospective Longitudinal Insurance Claims: Applying Techniques of Epidemiology).Design Meta-analysis of RCT-DUPLICATE data.Data sources Trials included in RCT-DUPLICATE, a demonstration project that emulated 32 randomised controlled trials using three real world data sources: Optum Clinformatics Data Mart, 2004-19; IBM MarketScan, 2003-17; and subsets of Medicare parts A, B, and D, 2009-17.Eligibility criteria for selecting studies Trials where the primary analysis resulted in a hazard ratio; 29 RCT-RWE study pairs from RCT-DUPLICATE.Results Differences and variation in effect sizes between the results from randomised controlled trials and real world evidence studies were investigated. …”
Get full text

Suprainguinal fascia iliaca compartment block in pediatric-aged patients: An educational focused review by Anuranjan Ghimire, Sidhant Kalsotra, Joseph D. Tobias, Giorgio Veneziano

“…Although neuraxial techniques were initially the primary techniques used for intraoperative and postoperative anesthesia and analgesia, many of these techniques have been replaced by selective nerve blockade. …”
Get full text

Information preferences of patients with chronic blood cancer: A qualitative investigation. by Debra A Howell, Dorothy McCaughan, Alexandra Smith, Russell Patmore, Eve Roman

“…<h4>Conclusions</h4>Varied, dynamic information preferences indicate that resources should be developed in a way that provides maximum choice, enabling patients to select relevant material at different time-points on their trajectory. …”
Get full text

Impact of “Assessment and Accreditation” Process on Quality of Higher and Medical Education in India: A Systematic Review and Meta-analysis by Venkata Venu Gopala Raju Srijampana, Bodhi Srividya Vennam, Phanindra Dulipala, Rajesh Potti

“…Introduction: India’s higher education system is evolving to meet global standards, driven by initiatives like the National Education Policy 2020. …”
Get full text

The myeloid switch: immune drivers in atopic dermatitis — roles in pathogenesis and emerging therapeutic targeting by Erik Kupschke, Erik Kupschke, Mirjam Schenk, Mirjam Schenk

“…This review highlights recent findings on the role of myeloid cells in the initiation, maintenance, and amplification of inflammation in AD. …”
Get full text

The evaluation of the coronary arteries calcification degree by the method of cardiovascular MSCT in patients with vitamin D and homocysteine metabolism disturbance by O. S. Nykonenko, A. O. Nykonenko, K. O. Chmul, V. V. Osaulenko

“…Traditionally, the selective coronary angiography is used to obtain an image of the CAs. …”
Get full text

Corticotropin-releasing hormone receptor-1 antagonist attenuates visceral hypersensitivity induced by trinitrobenzene sulfonic acid colitis and maternal separation in rats by Ryoko Hasegawa, Kumi Nakaya, Motoyori Kanazawa, Shin Fukudo

“…The same experiments were repeated after administration of the selective CRH-R1 antagonist CP-154,526 (20 mg/kg) or vehicle at 45 min before CRD. …”
Get full text

Cortico-striatal action control inherent of opponent cognitive-motivational styles by Cassandra Avila, Martin Sarter

“…Turning on cue or stopping at a red light requires attending to such cues to select action sequences, or suppress action, in accordance with learned cue-associated action rules. …”
Get full text

Investigating a role for PUB17 and PUB16 in the self‐incompatibility signaling pathway in transgenic Arabidopsis thaliana by Paula K. S. Beronilla, Daphne R. Goring

“…Abstract In Brassicaceae self‐incompatibility (SI), self‐pollen rejection is initiated by the S‐haplotype specific interactions between the pollen S cysteine‐rich/S‐locus protein 11 (SCR/SP11) ligands and the stigma S receptor kinases (SRK). …”
Get full text

Robust weighted ridge regression based on S – estimator by Taiwo Stephen Fayose, Kayode Ayinde, Olatayo Olusegun Alabi, Abimbola Hamidu Bello

“…The selected Ridge estimators and Robust S estimator in two weighted versions (True weight (Wo) and suggested new weight (W1)) were combined to respectively develop the Robust S Ridge and Robust S Weighted Ridge estimators. …”
Get full text

Characterization of fruit production and market performance in northwest Ethiopia by Mengistie Mossie, Alemseged Gerezgiher, Zemen Ayalew, Zerihun Nigussie, Asres Elias

“…Stemming from this logical ground, this study is initiated with the objective of characterizing production systems and market performance of fruits in Ethiopia, focusing on apple and mango crops. …”
Get full text

Determining the Bordetella LPS structural features that influence TLR4 downstream signaling by Kiruthika Manivannan, Yasmine Fathy Mohamed, Yasmine Fathy Mohamed, Rachel C. Fernandez

“…Upon recognizing bacterial lipopolysaccharide (LPS), human TLR4 initiates two distinct signaling pathways: the MyD88 pathway from the cell surface or the TRIF pathway following endocytosis. …”
Get full text

Enhancing cancer care through a knowledge-sharing model: a systematic review of Project ECHO® programmes in India by Sangeeta Bhuyan, Shikha Yadav, Amit Verma, Shama Bhati, Ankit Anand, Sandeep Bhalla, Apoorva Karan Rai

“…The review aimed to assess the scale and impact of ECHO’s initiatives, evaluate findings, examine the model’s implementation, and assess its acceptability among healthcare professionals (HCPs) in preventing and treating cancer. …”
Get full text

The Prevalence of Temporomandibular Disorder in Iran: A Literature Review by Sajad Ghorbanizadeh, Kamran Azadbakht, Hamid Badrian, Nakisa Torabnia

“…Finally, 22 completely related studies were selected to investigate the main objective. The Comprehensive Meta-analysis (CMA) software was used for data analysis in this systematic review.Results: Initially, 212 articles were retrieved, of which 116 were duplicate studies. …”
Get full text

Global glaciological models: a new stage in the development of methods for predicting glacier evolution. Part 2. Formulation of experiments and practical applications by T. N. Postnikova, O. O. Rybak

“…In the second part, we present the methods for setting up of numerical experiments with these models, including model initialization, climate forcing, calibration, and validation procedures. …”
Get full text

OptiSAIL: A system for the simultaneous retrieval of soil, leaf, and canopy parameters and its application to Sentinel-3 Synergy (OLCI+SLSTR) top-of-canopy reflectances by Simon Blessing, Ralf Giering, Christiaan van der Tol

“…This paper describes the selected algorithm for the ESA climate change initiative vegetation parameters project. …”
Get full text

PERMA.teach: a study on the effectiveness of a standardized positive education training program in Austria by Martin Wammerl, Martin Wammerl, Ulrike Lichtinger

“…IntroductionPERMA.teach is the largest Positive Education initiative in German-speaking countries, offering a structured training program to help teachers integrate well-being interventions based on the PERMA model into their classrooms. …”
Get full text

Drilling Rate of Penetration Prediction Based on CBT-LSTM Neural Network by Kai Bai, Siyi Jin, Zhaoshuo Zhang, Shengsheng Dai

“…This model integrates the capability of a two-dimensional convolutional neural network (2D-CNN) for multi-feature extraction, the advantages of bidirectional long short-term memory networks (BiLSTM) for processing bidirectional temporal information, and the dynamic weight adjustment of the time pattern attention mechanism (TPA) for extracting crucial information in BiLSTM, effectively capturing key features in temporal data. Initially, data are denoised using the Savitzky–Golay filter, and five correlation coefficient methods are employed to select input features, with principal component analysis (PCA) used to reduce model complexity. …”
Get full text

Women’s experiences of living with adenomyosis and perceptions of the diagnostic journey: a scoping review by Tim J Croudace, Margaret A Taylor, Margot McBride, Fiona E Muir

“…A manual hand-search of references of selected studies was conducted. Prespecified data were extracted, charted and categorised into themes.Results Six eligible studies were found, with themes describing impact and burdens, as well as several categories of unsupported needs. …”
Get full text

The effectiveness of RIPAT approach in influencing smallholder farmers’ agroecological transition in Ruangwa District, Tanzania by Nickson J. Ringo, John F. Kessy, Emmanuel T. Malisa

“…Data were collected from 252 randomly selected farmers using questionnaire surveys and focus group discussion, and analyzed using descriptive and inferential statistics. …”
Get full text