Unraveling the complex role of microglia in Alzheimer’s disease: amyloid β metabolism and plaque formation by Sho Takatori, Mayuna Kondo, Taisuke Tomita

“…Exploring potential therapeutic strategies that selectively enhance beneficial microglial functions while mitigating their detrimental effects remains an important goal.…”
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The role of coffee-based Agroforestry in improving food security through dietary diversification by Beshea Abdissa Chemeda, Feyera Senbeta Wakjira, Emiru Birhane

“…A multi-stage sampling procedure was used to select 402 sample households. Data were collected through household surveys, focus group discussions (FGDs), and key informant interviews. …”
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Continuous irrigation for refractory multidrug-resistant brain abscess in two patients by Nguyen Quang Thanh, Nguyen Trung Cap, Vu Dinh Phu, Mac Duy Hung, Nguyen Quoc Phuong, Dong Phu Khiem, Pham Ngoc Thach

“…These cases highlight the importance of considering continuous irrigation in selected patients and underscore the need for further research and multidisciplinary collaboration to optimise management protocols and improve patient outcomes.…”
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Preprocedural Mouthrinse During Dental Treatment in Covid -19 Patients: A Meta- analysis by Supinder Sudan, T.L Ravishankar, Puja C. Yavagal, M.D Nazamuddin Tafadar

“…This mouthrinse can be used 30 min before initiation of any dental treatment and even in between the procedure.…”
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The mechanism of functional up-regulation of P2X3 receptors of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine type 1 (FHM-1). by Swathi K Hullugundi, Michel D Ferrari, Arn M J M van den Maagdenberg, Andrea Nistri

“…A knock-in (KI) mouse model of FHM-1 expressing the R192Q missense mutation of the Cacna1a gene coding for the α1 subunit of CaV2.1 channels shows, at the level of the trigeminal ganglion, selective functional up-regulation of ATP -gated P2X3 receptors of sensory neurons that convey nociceptive signals to the brainstem. …”
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Place of tiotriazoline in the gallery of modern metabolitotropic medicines by I. F. Bielenichev, V. A. Vіzіr, V. Yo. Mamchur, O. V. Kuriata

“…The mechanism of action of Thiotriazolin is to increase the expression of antioxidant enzymes, reduce the concentration of free radicals, activate a compensatory malate-aspartate shunt of energy production, normalize the work of the Krebs cycle, and initiate Red / Oxi-dependent expression of transcription factors in ischemia. …”
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The Role of Automated Decision-Making in Modern Administrative Law: Challenges and Data Protection Implications by Grega Rudolf, Polonca Kovač

“…Design/Methodology/Approach: Utilising a combination of descriptive, normative, and doctrinal research methods, the study draws on recent regulatory initiatives, analyses selected ADM use cases in Slovenia and abroad, and closely examines the 2023 Schufa case decided by the Court of Justice of the European Union (CJEU). …”
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Cultural taboos and menstrual health: analysing practices in Gadchiroli’s Kurma Ghar (period huts) in Maharashtra by Sania Siddiqui, Karuna Nidhi

“…This practice is particularly prevalent among the Gond and Madiya ethnic groups in Maharashtra. Despite national initiatives aimed at improving menstrual health, Kurma Ghar continues to be widely practiced in the Gadchiroli district, where menstrual stigma and limited access to hygiene products remain significant concerns. …”
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Application value of multi-disciplinary collaborative diagnosis and treatment combined with CBL teaching model in gynecological oncology practice teaching by Fengrong Wen, Julan Mo, Renxiang Li

“…The questionnaire survey results indicated that the research group outperformed the control group in knowledge acquisition, learning initiative, learning interest, clinical analysis ability, clinical diagnosis, treatment thinking, teamwork ability, literature retrieval, and reading ability, and clinical language expression ability (p < 0.05). …”
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Optimizing the mechanical properties of sustainable self-compacting concrete contains industrial by-products by using Taguchi and Grey-Taguchi methods by Mahdi Mosafer, Ali Khodabakhshian, Mansour Ghalehnovi

“…Sixteen SCC mixtures were initially formulated using a standard L16 (45) orthogonal array comprising five factors, each with four levels. …”
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Public Housing Project Delivery in Nigeria: Quality versus Quantity by Oluwafemi Kehinde AKANDE, Lilian Chioma OBI-GEORGE, Jonam Jacob LEMBI, Ibrahim Adamu UMAR, Amos Musa TARNI, Adanna Joy NWOKORIE, Paul Haruna BABA

“…Nigeria, the most populous country in sub-Saharan Africa, has taken many initiatives to address its growing population's housing demands. …”
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Discovery of Genomic Targets and Therapeutic Candidates for Liver Cancer Using Single-Cell RNA Sequencing and Molecular Docking by Biplab Biswas, Masahiro Sugimoto, Md. Aminul Hoque

“…Based on molecular docking and binding-affinity scores with 36 receptor proteins, we proposed 10 potential therapeutic drugs, which we selected from a pool of 300 cancer meta-drugs. The choice of these drugs was further validated using 14 top-ranked published receptor proteins from a set of 42. …”
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THE EVALUATION OF COMPLIANCE TO ANTIHYPERTENSIVE THERAPY IN PATIENTS AFTER STROKE AND POSTSTROKE DEPRESSION DURING ANTIDEPRESSANT THERAPY by B. B. Fishman, A. I. Khoroshevskaya, A. A. Abdulin, G. G. Semenova, P. V. Starikov, O. V. Pavlova

“…Patients of group 1 (n=12) received adequate antihypertensive therapy and selective serotonin reuptake inhibitor paroxetine. …”
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Stakeholders' awareness and perception towards graphic health warning, opportunities and challenges for tobacco control policy in Nepal: A qualitative study. by Netra Lal Aryal, Binita Kumari Paudel, Babu Ram Pokhrel, Sushila Acharya, Saraswati Bhandari, Sheetal Bhandari, Manish Rajbanshi, Shalik Ram Dhital

“…Effective policy execution and community involvement were highlighted as critical to the success of tobacco control initiatives.…”
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Research on Feature Extraction of Performance Degradation for Flexible Material R2R Processing Roller Based on PCA by Yaohua Deng, Huiqiao Zhou, Kexing Yao, Zhiqi Huang, Chengwang Guo

“…The vibration signal features reduction dimension was realized, and F1,F2, and F3 contain 98.9% of the original vibration signal data, further illustrating that the method has high precision in feature parameters’ extraction and the advantage of eliminating the correlation between feature parameters and reducing the workload selecting feature parameters.…”
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Simultaneous triple cancer of the esophagus, pancreas and rectum treated with multimodal strategies: a case report by Hiroki Imamura, Hajime Hirose, Shunji Endo, Yasuji Hashimoto, Masashi Takeda, Shinya Kidogami, Yukako Mokutani, Tomoya Kishimoto, Shinichi Yoshioka, Shigeyuki Tamura, Yo Sasaki

“…Then treatment for pancreatic cancer was initiated by administering neoadjuvant chemotherapy with gemcitabine plus nab-paclitaxel. …”
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The Impact of Background Music on Flow, Work Engagement and Task Performance: A Randomized Controlled Study by Yuwen Sun

“…These findings reconcile the cognitive tuning and arousal–mood hypotheses by proposing a hybrid model where music initially operates through a novelty-driven dopamine release before transitioning to schema-based cognitive priming. …”
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Ranking data privacy techniques in cloud computing based on Tamir’s complex fuzzy Schweizer-Sklar aggregation approach by Jabbar Ahmmad, Hamiden Abd El-Wahed Khalifa, Hafiz Muhammad Waqas, Alhanouf Alburaikan, Taha Radwan

“…Then relying on these operational laws, we have initiated the notions of cartesian form of complex fuzzy Schweizer-Sklar power average and complex fuzzy Schweizer-Sklar power geometric AOs. …”
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Objective hyperemia and intraocular pressure changes following omidenepag isopropyl application. by Kana Tokumo, Tsuyoshi Yoneda, Yuta Nakaniida, Ryota Aoki, Shunsuke Nakakura, Taro Baba, Naoki Okada, Ayaka Edo, Hiromitsu Onoe, Hideaki Okumichi, Kazuyuki Hirooka, Diane Sonassa, Hitoshi Tabuchi, Yoshiaki Kiuchi, Hirokazu Sakaguchi

“…Here, we prospectively examined changes in hyperemia from before to 3 months after the initiation of the omidenepag isopropyl, a selective E-prostanoid receptor-2 receptor agonist, using hyperemia analysis software. …”
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Results of application for the treatment of bioingineering construction for occlusive vascular diseases in animal experiments by L. O. Bockeria, N. A. Chigogidze, I. D. Skhirtladze, M. V. Muradyan, N. T. Odishariya, M. M. Tkhagapsova

“…In seven experiments, 70 days after the operation was carried out repeated selective angiography to assess the patency of stents coated with cultured fibroblasts. …”
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