Safety and Antihypertensive Effect of Selara® (Eplerenone): Results from a Postmarketing Surveillance in Japan by Shoko Takahashi, Megumi Hiramatsu, Shinichi Hotta, Yukie Watanabe, Osamu Suga, Yutaka Endo, Isamu Miyamori

“…The change in blood pressure after initiation of eplerenone treatment was also examined. …”
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X-photon 3D lithography by fs-oscillators: wavelength-independent and photoinitiator-free by Dimitra Ladika, Antanas Butkus, Vasileia Melissinaki, Edvinas Skliutas, Elmina Kabouraki, Saulius Juodkazis, Maria Farsari, Mangirdas Malinauskas

“…Controlled energy deposition per focal volume is achieved due to localized heating enabling efficient 3D printing. Such spatio-selective photo-chemical cross-linking widens optical manufacturing capacity of non-photo-sensitive materials.…”
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The impact of human resource management on irrigation and drainage management in Indonesia by Khalisah Hayatuddin, Asel Mohmuod, Ainur O. Ongdash, Seyed Saeed Asghari Zonouz, Shukur-Ali Ataev

“…A mixed-methods approach was employed, combining quantitative surveys of 500 irrigation managers and engineers from five major islands with qualitative interviews of 50 selected participants. The research utilised stratified random sampling and conducted data collection from March to August 2023. …”
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Tracking the genetic diversity of SARS-CoV-2 variants in Nicaragua throughout the COVID-19 pandemic by Gerald Vásquez Alemán, Cristhiam Cerpas, Jose G. Juarez, Hanny Moreira, Sonia Arguello, Josefina Coloma, Eva Harris, Aubree Gordon, Shannon N. Bennett, Ángel Balmaseda

“…These sequences were selected nationwide and analyzed for variant classification, lineage predominance, and phylogenetic diversity. …”
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Novel PI3kδ inhibitor roginolisib synergizes with venetoclax in hematologic malignancies by Binu Kandathilparambil Sasi, Chiara Tarantelli, Stephen Martindale, Elisa Civanelli, Eleonora Cannas, Giulio Sartori, Alberto J. Arribas, Stacey M. Fernandes, Samantha J. Shupe, John-Hanson Machado, Svitlana Tyekucheva, Yue Ren, Michael Lahn, Lars van der Veen, Giusy Di Conza, Francesco Bertoni, Jennifer R. Brown

“…A clinical trial of roginolisib with venetoclax and an anti-CD20 antibody is initiating in CLL. …”
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Probing the optimal architecture and molecular mechanism of insect odorant receptor heteromeric channels by Wei Xue, Xiao-Li Lu, Tian-Min Zhang, Yi Guo, Yong-Hu Li, Gang Li, Chang Xu, Hui-Meng Lu

“…Abstract Insects have a powerful olfactory system that is far more selective and sensitive than artificial detectors. …”
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Evaluating the Energy Resources and Environmental Impacts for Blueberry Packaging Materials with a Focus on End-of-Life Scenarios by Viktoria Mannheim, Ulvi Moor, Liina Laumets, Klára Tóthné Szita

“…There are also ongoing initiatives to enhance sustainability in blueberry packaging by selecting appropriate materials. …”
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Multi-Threshold Remote Sensing Image Segmentation Based on Improved Black-Winged Kite Algorithm by Yi Zhang, Xinyu Liu, Wei Sun, Tianshu You, Xin Qi

“…Quantitative evaluations reveal substantial improvements in the dice coefficient across six randomly selected remote sensing images, achieving performance enhancements of 7.76%, 11.99%, 30.75%, 22.91%, 44.37%, and 18.55%, respectively. …”
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Establishing meaningful change thresholds for European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire CLL‐specific module domain scores: An analysi... by Laurie Eliason, Fatoumata Fofana, Lin Wang, Peter A. Riedell, Shien Guo

“…EORTC QLQ‐CLL17 and selected anchor measures were assessed at baseline and multiple postbaseline visits up to 24 months after treatment initiation. …”
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Nanotherapeutic strategies exploiting biological traits of cancer stem cells by Hongyu Wang, Wenjing Zhang, Yun Sun, Xican Xu, Xiaoyang Chen, Kexu Zhao, Zhao Yang, Huiyu Liu

“…Cancer stem cells (CSCs) represent a distinct subpopulation of cancer cells that orchestrate cancer initiation, progression, metastasis, and therapeutic resistance. …”
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Recent advances and challenges in solid sorbents for CO2 capture by Hamid Zentou, Bosirul Hoque, Mahmoud A. Abdalla, Ahmed F. Saber, Omar Y. Abdelaziz, Mansur Aliyu, Abdullah M. Alkhedhair, Abdullah J. Alabduly, Mahmoud M. Abdelnaby

“…Furthermore, the document highlights the significance of thermodynamic stability, sorbent selectivity, and impurity tolerance to enhance adsorption efficiency in various operating conditions. …”
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Assessment of calorie intake and micronutrient consumption in rural North-Central Nigeria by Abubakar Yah-Ya Ibrahim, Kayode Ayantoye, Ambali Olatunji Yusuf, Salau Shehu Abdulganiyu

“…Consequently, food security initiatives in these regions must include programs that are focused on dietary adequacy to promote productive and healthy living.…”
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Proteinuria and Progression of Renal Damage: The Main Pathogenetic Mechanisms and Pharmacological Approach by Elisa Longhitano, Vincenzo Calabrese, Chiara Casuscelli, Silvia Di Carlo, Salvatore Maltese, Adolfo Romeo, Massimo Calanna, Giovanni Conti, Domenico Santoro

“…Recent advancements include sodium–glucose cotransporter 2 inhibitors, initially used for glycemic control, now recognized for their renoprotective properties in both diabetic and non-diabetic populations. …”
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Regulation of Stress-Induced Immunosuppression in the Context of Neuroendocrine, Cytokine, and Cellular Processes by Evgenii Balakin, Ksenia Yurku, Mark Ivanov, Alexander Izotov, Valeriya Nakhod, Vasiliy Pustovoyt

“…The data also highlight the crucial role of cortisol and catecholamines (adrenaline and noradrenaline) in initiating immunosuppressive mechanisms under chronic stress.…”
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HDAC5, an early osimertinib-responsive gene, is a novel therapeutic target for the drug resistance in EGFR-mutant lung adenocarcinoma cells by Hanbing Lyu, Akihiko Ishimura, Ryusuke Suzuki, Khurelsukh Buyanbat, Gerelsuren Batbayar, Makiko Meguro-Horike, Shin-ichi Horike, Seiji Yano, Takeshi Suzuki

“…Furthermore, treatment with LMK235, a selective HDAC5 inhibitor, significantly increased global histone acetylation and enhanced osimertinib-induced apoptosis. …”
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The Effect of Coping Skills Training on Early Maladaptive Schemas, Health- Promoting Lifestyle, and Mental Well-Being in Individuals with Borderline Personality Disorder by Barzan Soleimani, Anvar Dastbaz, Sara Kazemi

“…Thirty participants were purposefully selected and randomly assigned to experimental and control groups,15 people each. …”
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Coordinated Role of Autophagy and ERAD in Maintaining Neuroendocrine Function by Preventing Prohormone Aggregation by Xuya Pan, Xing He, Su Wu, Na Xiong, Xinyu Hou, Heting Wang, Diane Somlo, Martin Spiess, Haiyang Wang, Jifeng Yang, Chunliang Li, Shasha Li, Wenbin Ma, Yanming Chen, Jun Cui, Ling Qi, Guojun Shi

“…However, the mechanisms governing the initiation and degradation of misfolded or aggregated proteins in neurons remain largely unknown in vivo. …”
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“Unraveling EMILIN-1: A Multifunctional ECM Protein with Tumor-Suppressive Roles” Mechanistic Insights into Cancer Protection Through Signaling Modulation and Lymphangiogenesis Con... by Samanta Muzzin, Enrica Timis, Roberto Doliana, Maurizio Mongiat, Paola Spessotto

“…EMILIN-1 (Elastin Microfibril Interface Located Protein 1) is an extracellular matrix homotrimeric glycoprotein belonging to the EMILIN/Multimerin family, with both structural and regulatory roles, increasingly recognized for its tumor-suppressive functions. Initially identified for its involvement in elastogenesis and vascular homeostasis, EMILIN-1 has gradually emerged as a key player in cancer biology. …”
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Seroprevalence of strongyloidiasis and toxocariasis among hypereosinophilic patients seeking care at diagnostic centers in Tehran, Iran by Zohre Fakhrieh- Kashan, Eshrat Beigom Kia, Mohammad Taghi Haghi Ashtiani, Seyed Reza Dabaghi, Mohammad Amin Sari, Enayat Darabi

“…The aim of this study was to explore the seroprevalence of Strongyloides stercoralis and Toxocara spp. among hypereosinophilic patients undergoing evaluation at selected diagnostic centers in Tehran. Methods: A comprehensive questionnaire was completed, and a blood sample was collected from each participant. …”
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Study on the Numerical Simulation of Coupling Interference Law of AC Transmission Lines to Buried Pipelines by ZHAO Yalei, CHEN Wei, CHENG Wei, LAN Wei, WU Xiang, MA Liming

“…In energy public corridors， the similar routing of AC transmission lines and buried pipelines inevitably causes the pipeline to enter the AC interference zone， leading to pipeline AC corrosion， abnormal cathodic protection systems， and posing a threat to pipeline operation safety.To study the coupling interference law of AC transmission lines on buried pipelines， based on the pipeline equivalent circuit and electromagnetic induction theory， a model of AC interference of transmission lines on buried pipelines was established using CDEGS.The AC interference intensity and safety distance under typical transmission line characteristic parameters，pipeline parameters and laying environment parameters were calculated.Results showed that the AC interference voltage on the pipeline was directly proportional to the AC transmission current.When the parallel length between the 3PE pipeline and the transmission line was less than 20 km， the AC interference voltage was directly proportional to the parallel length.When the distance between the pipelines and transmission lines was small，the phase spacing and average height significantly impacted the AC interference voltage.As the distance increased， the AC interference voltage initially increased and then decreased.Based on extensive numerical simulations， a safety distance determination chart and AC interference voltage curve suitable for on-site engineering were proposed， providing a reference for selecting new pipeline routing and protecting existing pipelines from interference， thereby reducing the risk of AC interference on pipelines.…”
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