A phosphorylation switch in the Mediator MED15 controls cellular senescence and cognitive decline by Haozheng Li, Yuanming Zheng, Chunlei Yuan, Jiayi Wang, Xiaying Zhao, Ming Yang, Defei Xiong, Yenan Yang, Yunpeng Dai, Yiming Gao, Yuqi Wang, Lei Xue, Gang Wang

“…Transforming growth factor-β selectively induces CDK1-mediated MED15 T603 phosphorylation to control SASP gene expression. …”
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Evolution of Regional Innovation Strategies Towards the Transition to Green Energy in Europe 2014–2027 by Korneliusz Pylak, Jakub Pizoń, Ewa Łazuka

“…In addition, the study highlights the selective prioritization of decarbonization and energy efficiency goals, while goals such as consumer empowerment and offshore wind energy remain undervalued. …”
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CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to palbociclib by Eric Raspé, Katia Coulonval, Jaime M Pita, Sabine Paternot, Françoise Rothé, Laure Twyffels, Sylvain Brohée, Ligia Craciun, Denis Larsimont, Véronique Kruys, Flavienne Sandras, Isabelle Salmon, Steven Van Laere, Martine Piccart, Michail Ignatiadis, Christos Sotiriou, Pierre P Roger

“…We had shown that the activating T172 phosphorylation of CDK4 is the central rate‐limiting event that initiates the cell cycle decision and signals the presence of active CDK4. …”
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Prevalence of red, orange, and green microbial complexes in periodontal pockets of chronic kidney disease patients on hemodialysis: a systematic review and meta-analysis by Diego José Gambin, Jayne de Oliveira Manica, Daniela Dal Olmo Merib, Caroline Mirek, Felipe Gomes Dallepiane, Thais Mageste Duque, João Paulo De Carli, Micheline Sandini Trentin

“…Quantitative analysis with proportion meta-analysis was also performed. 4,737 studies were initially selected, and five were included. The study verified the prevalence of the green complex - Aggregatibacter actinomycetemcomitans (6.69%); the orange complex - Prevotella intermedia (16.85%) and Prevotella nigrescens (37.51%); and the red complex - Treponema denticola (29.11%), Porphyromonas gingivalis (49.45%), and Tannerella forsythia (56.37%), the most predominant microorganism. …”
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Conversion surgery for advanced jejunal adenocarcinoma with multiple peritoneal metastases: a case report by Miku Obayashi, Shimpei Otsuka, Ryo Ashida, Katsuhisa Ohgi, Mihoko Yamada, Takeshi Kawakami, Katsuhiko Uesaka, Teiichi Sugiura

“…Chemotherapy was continued, and four years after the initiation of therapy, the patient showed no evidence of disease progression. …”
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Nomenclatural standards of black currant cultivars bred by Sverdlovsk Horticultural Breeding Station. Part II by L. V. Bagmet, E. M. Chebotok, A. V. Shlyavas

“…Vavilov All-Russian Institute of Plant Genetic Resources (VIR) has initiated and is working on the creation of nomenclatural standards of domestic cultivars. …”
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Telemedical Support in Patients with Chronic Heart Failure: Experience from Different Projects in Germany by Axel Müller, Johannes Schweizer, Thomas M. Helms, Micheal Oeff, Claudia Sprenger, Christian Zugck

“…In Germany, various telemedical monitoring projects for patients with chronic heart failure have been initiated in the past few years; seven of them are presented here. …”
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An Update on a World Wide Study of Bullets Fired From 10 Consecutively Rifled 9mm Ruger Pistol Barrels by James E. Hamby, Eric Warren, David J. Brundage, Nicholas D. K. Petraco, James W. Thorpe

“…This technical note is the latest update on a continuing study, first designed and initiated by Brundage et al. over twenty years ago. …”
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A neural network-based method for input parameter optimization of edge transport modeling utilizing experimental diagnostics by Y. Luo, S. Xu, Y. Liang, E. Wang, J. Cai, Y. Feng, D. Reiter, A. Knieps, S. Brezinsek, D. Harting, M. Krychowiak, D. Gradic, P. Ren, D. Zhang, Y. Gao, G. Fuchert, A. Pandey, M. Jakubowski, the W7-X Team

“…A neural network-based method is developed to fast optimize EMC3-EIRENE input parameters, enabling EMC3-EIRENE to produce synthetic data that closely match experimental measurements on Wendelstein 7-X. Initially, an EMC3-EIRENE simulation database covering a range of key input parameters is generated. …”
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Collaborative Filtering Techniques for Predicting Web Service QoS Values in Static and Dynamic Environments: A Systematic and Thorough Analysis by Ghizlane Khababa, Sadik Bessou, Fateh Seghir, Nor Hazlyna Harun, Abdulaziz S. Almazyad, Pradeep Jangir, Ali Wagdy Mohamed

“…In recent years, the rapid growth of Web Services (WSs) has led to a proliferation of functionally similar options, making Quality of Service (QoS) a crucial factor for users in selecting the most suitable services. Predicting QoS values and recommending optimal services remain challenging, particularly in dynamic environments. …”
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HuoXueJieDu Formula Alleviates Diabetic Retinopathy in Rats by Inhibiting SOCS3-STAT3 and TIMP1-A2M Pathways by Hongliang Wang, Wei Xing, Shijie Tang, Zhenglin Wang, Tiantian Lv, Yan Wu, Shuzhen Guo, Chun Li, Jing Han, Ruixin Zhu, Wei Wang

“…The administration of HXJD was initiated at 20 weeks after diabetes induction and continued for 12 weeks. …”
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Mesh Stiffness and Dynamic Modeling and Analysis of Modified Straight Bevel Gears by Ding Zhang, Ze-Hua Hu, Wen-Tao Liu, Jin-Yuan Tang, Zhou Sun, Zhao-Yang Tian

“…Finally, by comparing the dynamic characteristics under different modification conditions, the study further elucidates that selecting the appropriate modification method and amount according to different service scenarios is an effective means to suppress gear transmission vibration. …”
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Chemoembolization with HepaSpheres in the treatment of recurrent pelvic tumors by A. G. Kedrova, D. P. Lebedev, E. A. Zvezdkina, D. A. Astakhov, V. V. Kosyy, R. V. Ishchenko

“…Selective catheterization of dominant arteries in recurrent tumors along with chemoembolization with drug-eluting microspheres is extremely challenging, since most of recurrent tumors have a well-developed neovascular network. …”
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Regional Variation in Comorbid Prediabetes and Diabetes and Associated Factors among Hypertensive Individuals in Rural Bangladesh, Pakistan, and Sri Lanka by Liang Feng, Aliya Naheed, H. Asita de Silva, Imtiaz Jehan, Rubhana Raqib, Md Tauhidul Islam, Nathasha Luke, Anuradhani Kasturiratne, Hamida Farazdaq, Sahar Senan, Tazeen H. Jafar, COBRA-BPS Study Group

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Vesicular Stomatitis Virus: Insights into Pathogenesis, Immune Evasion, and Technological Innovations in Oncolytic and Vaccine Development by Mohamed Mustaf Ahmed, Olalekan John Okesanya, Bonaventure Michael Ukoaka, Adamu Muhammad Ibrahim, Don Eliseo Lucero-Prisno

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The association between dolutegravir based first-line antiretroviral regimens and dyslipidemia among adults living with HIV on follow-up at health facilities in Hawassa city admini... by Agete Tadewos Hirigo, Alemayehu Abera, Daniel Yilma, Ayalew Astatkie, Zelalem Debebe

“…This study aimed to assess the association between DTG-based regimens and dyslipidemia among adults initiated on ART after the test-and-treat implementation in Ethiopia. …”
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A narrative review of veterinary pharmacovigilance situations and prospects in East African countries by Yesuneh Tefera Mekasha, Sete Nigussie, Abibo Wondie Mekonen, Kassahun Berrie, Asnakew Mulaw, Melaku Getahun Feleke

“…The search strategies relied heavily on selecting relevant published findings related to veterinary pharmacovigilance status, veterinary adverse drug event reporting practice, and collaborative efforts in veterinary pharmaceutical sectors within the East African landscape. …”
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Plasma cytokine levels and PCOS risk: Mendelian randomization analysis reveals IL6R as a preventive factor by Xiaopei Li, Yan Li, Bumei Zhang, Jianmei Wang, Yang Yang, Yongrui Du

“…Cytokines play diverse roles in the initiation and progression of inflammation, contributing to this inflammatory milieu. …”
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Colostrum feeding practice and associated factors among mothers who come for postnatal care to Asella referral and teaching hospital, Arsi Zone, South-East Ethiopia by Gisha Haji, Gebi Agero, Amde Eshete, Abdurahman Hasan, Ahmed Hiko

“…BackgroundEvery day throughout the world more than 4,000 infants and young children die because colostrum feeding was not initiated within an hour of birth as recommended by the World Health Organization (WHO)/United Nations Children’s Fund. …”
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Viral load change and time to death among adult HIV/AIDS patients on ART after test-and-treat in Northwest Ethiopia: a retrospective multi-center follow-up study using Bayesian joi... by Eyob Tilahun Abeje, Eskezyiaw Agedew, Bekalu Endalew, Gedefaw Diress Alen

“…IntroductionAmong patients infected with Human Immunodeficiency Virus who are on antiretroviral therapy, nearly one-fifth develop viral load rebound within 2 years of initiation of therapy. Studies on viral load change are limited in Ethiopia. …”
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