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7081
Prognostic Impact of Oncogenic Fibroblast Growth Factor Receptor Alterations in Patients With Advanced Solid Tumors in a Real‐World Setting
Published 2025-02-01“…Patients without FGFR alterations (FGFRneg) were matched 3:1 with patients with FGFRalt using a combination of exact matching on tumor type and Mahalanobis‐distance matching on selected clinical confounders. The primary endpoint was OS from time of initiation of first‐line therapy in patients with FGFRalt versus FGFRneg. …”
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7082
Impact of local therapy in metastatic renal cell carcinoma during medical treatment in a retrospective analysis
Published 2025-07-01“…Our study has enhanced our understanding of LT utilization in mRCC after MT is already initiated. Ultimately, the inclusion of LT could improve OS in selected patients receiving MT.…”
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7083
An experimental target-based platform in yeast for screening Plasmodium vivax deoxyhypusine synthase inhibitors.
Published 2024-12-01“…DHS proteins from many are sufficiently different from their human orthologs for selective targeting against infectious diseases; however, no DHS inhibitor selective for parasite orthologs has previously been reported. …”
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7084
Potential targets for the new anti-tuberculosis drug of the diarylquinoline group thiozonide
Published 2025-06-01“…Compounds from the ChEMBL database were selected for the analysis, and structurally similar molecules were identified using the Tanimoto similarity measure. …”
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7085
Norepinephrine inhibits cell cycle re‐entry of neonatal rat ventricular cardiomyocytes characterized by the absence of de novo nestin expression
Published 2025-08-01“…Phorbol 12,13‐dibutyrate (PDBu; 100 nM) treatment attenuated 5‐bromo‐2′‐deoxyuridine incorporation, and SB203580 treatment predominantly initiated re‐entry into the cell cycle of the NNVM subpopulation characterized by de novo nestin expression. siRNA‐mediated PKC‐α protein downregulation in NNVMs selectively suppressed PDBu/SB203580‐mediated de novo nestin and subsequent cell cycle re‐entry. …”
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7086
The Effect of the COVID-19 Pandemic on Prescribing Medications for Opioid Use Disorder in the Mid-Michigan Region
Published 2025-04-01“…There was no significant difference in the percentage of new MOUD prescriptions among the selected cohort between the 2 selected timeframes, nor was there a significant difference in the prescriber/setting of new prescriptions. …”
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7087
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7088
The influence of farm connectedness on foot‐and‐mouth disease outbreaks in livestock
Published 2024-12-01“…Increased levels of connectivity of the initially infected farm had a significant incremental effect on the epidemic length and the number of farms, cattle, and sheep lost. …”
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7089
Collaborative work processes in establishing a MiniMaria treatment center for youth substance addiction: a qualitative inquiry of county council healthcare and municipal efforts
Published 2024-10-01“…Methods The municipality and county council were selected based on purposive sampling, owing to the proximity and accessibility of the field. …”
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7090
Patterns of postnatal weight gain and its predictors among preterm very low birth weight neonates born in Bahir-Dar city public hospitals, 2022: A cross sectional study.
Published 2025-01-01“…Mode of delivery, birth z-score, initiation time of the first feeding, and respiratory distress syndrome were associated with postnatal weight gain. …”
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7091
Theranos: the Ethics of Innovation and Deception in Healthcare Technology
Published 2024-09-01“…This analysis examines the company's fraudulent claims regarding its blood-testing technology, which promised groundbreaking results using minimal blood samples. Initially lauded for its potential, Theranos attracted significant investment and partnerships before facing growing scrutiny due to internal whistleblower accounts and investigative journalism. …”
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7092
PEMBERDAYAAN PETERNAK RUMINANSIA MELALUI PELATIHAN PEMBUATAN UREA MOLASSES BLOCK DI NAGARI PANGIAN KECAMATAN LINTAU BUO KABUPATEN TANAH DATAR
Published 2025-06-01“…A total of 30 active farmers participated, selected through coordination with local village authorities. …”
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7093
Challenges and solutions to nurse-delivered integrated primary health care in Nelson Mandela Bay
Published 2025-06-01“…Semi-structured interviews were conducted with nine nurses working in the selected facilities. Data were thematically analysed. …”
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7094
Assessment of the presence of antibiotic residues in meat from small-scale broiler farms in the Pwani region of Tanzania
Published 2024-12-01“…Samples taken from four-week-old birds tested positive for another antibiotic, sulfamethazine (SF), which was not initially one of the five antibiotics selected for this study. …”
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7095
Plant Growth-Promoting Rhizobacteria Isolated from Degraded Habitat Enhance Drought Tolerance of Acacia (Acacia abyssinica Hochst. ex Benth.) Seedlings
Published 2020-01-01“…The strains with the best DS tolerance ability were selected for the greenhouse trials with acacia plants. …”
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7096
Melatonin: An Anti-Tumor Agent in Hormone-Dependent Cancers
Published 2018-01-01“…Melatonin (N-acetyl-5-methoxytryptamine) is a hormone synthesized and secreted by the pineal gland mainly during the night, since light exposure suppresses its production. Initially, an implication of this indoleamine in malignant disease was described in endocrine-responsive breast cancer. …”
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7097
Structural findings obtained through Optic Coherence Tomography and Magnetic Resonance in Glaucoma: Systematic Review
Published 2025-02-01“…Methods: Following PRISMA guidelines, a systematic review of the current literature was conducted using the PubMed, Scopus, and Cochrane Library databases, searching for Medical Subject Headings (MeSH) terms related to optical coherence tomography, OCT, spectral-domain, magnetic resonance imaging, and glaucoma. Initially, 719 articles were identified. Independently, two researchers screened for duplicates, applied eligibility criteria, and selected 28 articles for data extraction and evaluation. …”
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7098
Poverty alleviation programmes and ruralization of corruption in Nigeria: A case study of Community and Social Development Programme (CSDP) in Edo State
Published 2025-08-01“…The study deployed the elite theory to demonstrate elite sabotage of poverty alleviation initiatives in the Nigerian rural areas. The study employed an in-depth interview to gather responses from 109 participants knowledgeable about the various CSDPs located across the selected communities. …”
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7099
Simulation of the Extruder Screw Parameters
Published 2020-12-01“…In the course of experimental studies, a value of impact strength was obtained that corresponded to the standard value of the initially selected steel grade (38 kilojoules per cubic meter), but didn’t meet the requirements for this structural element (at least 50 kilojoules per cubic meter).…”
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7100
On the Issue of Developing PROM as Part of the Value-based Healthcare
Published 2025-06-01“…Since the use of PROM in Russian healthcare has not yet widely used, but have proven effective in supporting value-based healthcare initiatives abroad, exploring methods for developing and selecting these measures is becoming a relevant trend. …”
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