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Suggested Topics within your search.
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6241
Ubiquitin-specific peptidases in lymphoma: a path to novel therapeutics
Published 2024-11-01“…BackgroundUbiquitin-specific peptidases (USPs), also known as deubiquitinating enzymes (DUBs), play a crucial role in maintaining cellular homeostasis by selectively removing ubiquitin molecules from targeted proteins. …”
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6242
AI-driven healthcare innovations for enhancing clinical services during mass gatherings (Hajj): task force insights and future directions
Published 2025-07-01“…The task force constructed ten statements to guide future initiatives. Conclusion Expanding the role of AI in healthcare during MGs will help optimize healthcare outcomes and utilization. …”
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6243
Genomic epidemiology and evolution of Bordetella pertussis under the vaccination pressure of acellular vaccines in Beijing, China, 2020–2023
Published 2025-12-01“…Evolutionary analysis revealed significant genetic shifts associated with the introduction of vaccines, particularly acellular vaccines. Initially, the prevalent genotypes included ptxP-1, prn-1, ptxA-2, fim2-2, and fim3-2. …”
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6244
Medication non-adherence: reflecting on two decades since WHO adherence report and setting goals for the next twenty years
Published 2024-12-01“…Ten international experts, five from Europe and five from the United States, were assigned to these dimensions and participated in structured online discussions. Initially, based on their desk reviews, experts identified significant achievements and future targets. …”
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6245
Safety and efficacy of simple training protocol in patients after mild traumatic brain injury
Published 2024-11-01“…The aim of this prospective study was to evaluate the effect and safety of selected training protocol in patients after mTBI. …”
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6246
The Investigation of 84 TESS Totally Eclipsing Contact Binaries
Published 2025-01-01“…., 84 totally eclipsing contact binaries with stable light curves were selected. The Transiting Exoplanet Survey Satellite light curves of these 84 targets were studied using the Physics Of Eclipsing Binaries code. …”
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6247
Pharmacophore-based virtual screening and in silico investigations of small molecule library for discovery of human hepatic ketohexokinase inhibitors for the treatment of fructose...
Published 2025-04-01“…Ketohexokinase C (KHK-C), a pivotal enzyme in fructose metabolism, catalyzes the phosphorylation of fructose to fructose-1-phosphate, initiating a cascade of downstream metabolic processes. …”
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6248
Co-creating mental health promotion and prevention interventions with groups in vulnerable situations in Europe: a mixed-methods study protocol for co-creation implementation and p...
Published 2025-07-01“…The selection of intervention scenarios for implementation was performed using scenario-based workshops involving stakeholders in six partner countries. …”
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6249
Understanding mental health among university students in Kenya: what role do family support and age play?
Published 2025-05-01“…Additionally, integrating family engagement initiatives to strengthen family support structures can serve as a protective factor against mental health challenges. …”
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6250
Combined immunotherapy with dendritic cells and cytokine-induced killer cells for solid tumors: a systematic review and meta-analysis of randomized controlled trials
Published 2024-12-01“…Two authors independently performed study selection and data extraction, with disagreements resolved through consensus or consultation with a third reviewer. …”
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6251
Identification and validation of diagnostic biomarkers and immune cell abundance characteristics in Staphylococcus aureus bloodstream infection by integrative bioinformatics analys...
Published 2024-11-01“…Overall, three candidate hub genes (DRAM1, PSTPIP2, and UPP1) were identified initially for S. aureus bloodstream infection diagnosis. …”
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6252
Machine Learning Prediction of Airfoil Aerodynamic Performance Using Neural Network Ensembles
Published 2025-07-01“…The novelty of this study lies in the demonstration that the same machine learning model, trained on identical data and architecture, can exhibit up to 250% variation in prediction error solely due to differences in random seed selection. This finding highlights the often-overlooked impact of seed initialization on model performance and highlights the necessity of treating seed choice as an active design parameter in ML aerodynamic predictions.…”
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6253
Midazolam infusions for therapeutic management of pediatric refractory status epilepticus: a systematic review
Published 2025-04-01“…Twelve studies reported that seizure cessation occurred at a mean time of 1.4–546.0 min (range 0–720 min) after midazolam initiation. In 8 of these studies, effective midazolam doses clustered at 2.0–5.0 μg/kg/min (0.12–0.30 mg/kg/h), with seizure cessation occurring within 10–70 min in 204/221 (92%) participants. …”
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6254
Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials.
Published 2017-08-01“…Outcomes were guided by Initiative on Methods, Measurement and Pain Assessment in Clinical Trials guidelines, with pain relief and safety as the primary outcomes. …”
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6255
Historical Slovenian Language Resources
Published 2012-06-01“…It contains about 5 million words of hand-corrected transcriptions from the following digitised texts: • Slovenian books and editions of the newspaper »Kmetijske in rokodelske novice«, digitised by the National University Library (NUK) in the frame of the EU project IMPACT (5000 pages); • Digital library AHLib,1 comprising Slovenian books translated from German (100 books); • A selection of Slovenian books2 All three resources (corpus, lexicon, collection) are encoded according to the Text Encoding Initiative Guidelines TEI P5, which enable the definition of XML schemas for encoding texts for scholarly purposes. …”
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6256
Blockchain Research and Development Activities Sponsored by the U.S. Department of Energy and Utility Sector
Published 2025-01-01“…Department of Energy (DOE) and comparing them with industry-funded initiatives. A total of 110 funded activities within the U.S. power industry were successfully tracked and mapped into a newly developed categorization framework. …”
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6257
Modulation of Biochemical Traits in Cold-Stored ‘Karaerik’ Grapes by Different Edible Coatings
Published 2025-06-01“…We conclude that edible coating selection significantly influences grape biochemical stability during cold storage, with CMC emerging as a superior choice for maintaining certain quality parameters.…”
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6258
Identification of single nucleotide polymorphisms (SNPs) associated with heat stress and milk production traits in Chinese holstein cows
Published 2025-05-01“…In our previous work, the eukaryotic translation initiation factor 4E (EIF4E), heat shock protein family A member 4 (HSPA4), and inositol 1,4,5-trisphosphate receptor type 2 (ITPR2) genes were found to play critical roles in the HS response of dairy cows. …”
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6259
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6260
Landscape Strategies in Architecture
Published 2019-12-01“…The core of this thesis is three case studies of architectural designs that approach a building like a landscape. A selection of analytical techniques is applied to key cases in three central chapters. …”
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