Network Pharmacology and In Vivo Evaluation of Lycium barbarum Polysaccharide in Preventing Perfluorooctanoic Acid-Induced Damage in Broilers by Nana Gao, Wenmei Yao, Yang Li, Xu Liu, Heping Bai, Xiaodan Wang

“…To examine the guarding effects of Lycium barbarum polysaccharides (LBP) on liver and gut injury induced by perfluorooctanoic acid (PFOA) in broilers. Initially, a dose selection experiment for PFOA modeling was conducted. …”
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Atezolizumab Plus Bevacizumab in Patients with Unresectable Hepatocellular Carcinoma: Real-World Experience From a US Community Oncology Network by Cosgrove D, Tan R, Osterland AJ, Hernandez S, Ogale S, Mahrus S, Murphy J, Wilson T, Patton G, Loaiza-Bonilla A, Singal AG

“…These data can help guide selection of appropriate treatment candidates and maximize the benefits of atezo-bev in routine clinical practice.Keywords: advanced HCC, first-line, systemic treatment, real-world evidence…”
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Enhancing surgical safety in lateral calcaneal plating: a cadaveric study on screw placement and fluoroscopic optimisation by Mahmut Kalem, Merve Dursun Savran, Mehmet Yilmaz, Ercan Şahin, Halil İbrahim Acar

“…For each screw, the appropriate length was initially measured, but to facilitate identification during subsequent medial dissection, longer screws were intentionally inserted. …”
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Do Consumers Want to Create Shared Values? Building Trust in Times of Whitewashing by Joanna Lemańczyk, Magdalena Stefańska

“…Implications / Recommendations: The selected research method (IDI) allows the authors to explore the issue and identify the factors that prevent respondents from undertaking business initiatives toward creating shared value. …”
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Early extracorporeal membranous oxygenation and burn excision in severe burn and inhalation injury by Andrew P. Bain, Isabel Garcia, Matthew Leveno, Chiaka Akarichi

“…Veno-venous ECMO was initiated 12 h after injury, with a total ECMO run of 523 h. …”
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Expert identification blitz: A rapid high value approach for assessing and improving iNaturalist identification accuracy and data precision and confidence by Thomas Mesaglio, Kelly A. Shepherd, Juliet A. Wege, Russell L. Barrett, Hervé Sauquet, Will K. Cornwell

“…Of the 7,000 records initially identified to a species level, 92% were correctly identified. …”
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Perspectives of healthcare stakeholders in Nigeria on the impact of COVID-19 on health services by Adeponle O. Adeoye, Yewande T. Nejo, Chinwe L. Ochu, Josephine Bayigga, Rodgers R. Ayebare, Adedayo O. Faneye, Charles O. Adewemimo, Oluwaseun Emmanuel Falayi, Adeniyi Francis Fagbamigbe, Prosper Okonkwo, Adewale Victor Opayele, Gloria Ogochukwu Nwiyi, Sunday Obiajunwa Eziechina, Ikemefule Rex Uzoma, Priscilla Ibekwe, Tamrat Shaweno, Nebiyu Dereje, Francis Kakooza, Mosoka Papa Fallah, Georgina Njideka Odaibo

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The Effects of Pregnancy and Childbirth on Women's Health-Related Quality of Life: A Scoping Review by Asmaa Othman

“…A total of 82 articles were initially retrieved. Twenty-four duplications were removed. …”
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Identification of inflammation related gene signatures for bladder cancer prognosis prediction by Yonggui Xiao, Danping Xu, Erhao Bao, Zijie Liu, Xiaomao Zhou, Xia Li, Lijun Li

“…Abstract Early diagnosis and treatment of bladder cancer are crucial, and since inflammation plays a role in all stages of bladder cancer, this study aims to develop a model based on inflammation-related genes to accurately predict patient prognosis. The data were initially processed through differential analysis and prognostic correlation analysis, then a Least absolute shrinkage and selection operator (LASSO) regression model was constructed by M-cohort and a nomogram was designed to increase the model readability. …”
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Health Service‐Related Determinants of Health‐Seeking Behavior during Malaria Fever in a High‐Risk Region of Nepal by Ashok Kumar Paudel, Muni Raj Chhetri, Prem Prasad Panta, Nibha Rani Pandey

“…Methods Using a cross‐sectional descriptive design with a mixed‐method approach, the research focused on Kanchanpur district, selected from 20 high‐risk malaria districts of Nepal. …”
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Genome-wide discovery of circulating cell-free DNA methylation signatures for the differential diagnosis of triple-negative breast cancer by Lijing Gao, Yanbing Li, Chao Qu, Yan Dong, Qingzhen Fu, Haibo Zhou, Ning Zhao, Xianyu Zhang, Da Pang, Yashuang Zhao

“…Least absolute shrinkage and selection operator (LASSO) regression was applied to select optimal markers. …”
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Core Outcome Set Development for Tension-Type Headache Treatment Using Traditional Chinese Medicine: Protocol for a Delphi Consensus Study by Guojing Fu, Yunmeng Chen, Xiao Liang, Chunli Guo, Xueming Fan, Xiao Gong, Wenjie Chen, Jing Teng, Jun Tang, Xing Liao, Jingjing Wei, Yunling Zhang

“…However, the lack of standardized evidence—such as inconsistencies in outcome selection and reporting in clinical studies, a lack of consensus on outcomes and measures, high risks of selective reporting bias, and missing data—has limited the development of robust evidence supporting the efficacy of TCM in treating TTH. …”
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Effect of Machine Learning on Risk Stratification for Antiretroviral Treatment Failure in People Living with HIV by Zhang W, Ren L, Yang K, Yan J, Yu Q, Qi S, Ruan H, Zhao D, Ruan L

“…Multivariable logistic regression, with variables selected through least absolute shrinkage and selection operator (LASSO) regression, was employed. …”
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Efficacy and Safety of Various Intravenous Thrombolytics for Acute Ischemic Stroke (AIS) at Various Dosages: A Systematic Review and Network Meta-Analysis by Yibin Hu, Shengxian Wu, Haixuan Zhang, Kangfeng Wang, Lijuan Zhang, Yizheng Ma, He Li

“…Only data from participants with AIS treated with various intravenous thrombolytics within the 4.5-h time window were included. Among initially identified studies, 16 met the selection criteria. …”
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Anti-Inflammatory Versus Antifibrotic Therapies for the Management of Rheumatoid Arthritis–Associated Interstitial Lung Disease: Protocol for a Systematic Review and Meta-Analysis... by Sneh Sonaiya, Alexandra Jianu, Nicholas Jianu, Kavita Batra

“…In contrast, antifibrotic therapies such as pirfenidone and nintedanib, initially developed for idiopathic pulmonary fibrosis, are now being explored for their potential in treating fibrosing variants of RA-ILD. …”
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Risk prediction of QTc prolongation occurrence in cancer patients treated with commonly used oral tyrosine kinase inhibitors: machine learning modeling or conventional statistical... by Hsiang-Wen Lin, Tien-Chao Lin, Chien-Ning Hsu, Tzu-Pei Yeh, Yu-Chieh Chen, Liang-Chih Liu, Chen-Yuan Lin

“…They also underscore the importance of screening baseline ECG before initiating TKIs to assess the risk of QTc prolongation, facilitating early intervention and prevention in the future.…”
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A Brief Report on a Systematic Review of Real-World Effectiveness Studies of ICS/LAMA/LABA for Treatment of Adults with Asthma in the US by Stephen G. Noorduyn, Kejsi Begaj, Amber Martin, Sergio Forero-Schwanhaeuser, Kassandra Schaible, Alison Moore, Rosirene Paczkowski

“…Although inclusion of observational studies can result in reporting/selection bias, we identified greater clinical benefits with triple therapies versus dual therapies.…”
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Microplastics in beach sediments, seawater, and common fish in tourist destinations by M. Go, A. Ybanez, A. Ilano, F. Cababat, L. De La Calzada

“…This study monitors microplastic contamination in marine environments at tourist destinations and suggests policies and initiatives that encourage tourism operators, locals, and tourists to adopt practices that reduce microplastic pollution. …”
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Identification and Validation of Key Genes Involved in the Coupling of Mitochondria-Associated Endoplasmic Reticulum Membrane in Hemorrhoidal Disease by Mao L, Rao Z, Wang Y, Yang J, He J, Zheng Z, Chen L

“…Differential expression analysis and single-sample Gene Set Enrichment Analysis (ssGSEA) scores were initially employed to identify candidate genes. Key genes were further refined using Least Absolute Shrinkage and Selection Operator (LASSO) and Protein-Protein Interaction (PPI) networks. …”
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Mobile Phone Auscultation Accurately Diagnoses Chronic Obstructive Pulmonary Disease Using Nonlinear Respiratory Biofluid Dynamics by Caroline Emily Gosser, Luther Daniel, Martin Huecker, Rodrigo Cavallazzi, Hiram Rivas, Jarred Jeremy Thomas, Ryan Close

“…The recordings from the egophonic and axillary sites were initially modeled separately and then combined in a single composite model. …”
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