Synthesis and evaluation of carmofur analogs as antiproliferative agents, inhibitors to the main protease (Mpro) of SARS-CoV-2, and membrane rupture-inducing agents by Tiffany Gu, Amber Lu, Xina Wang, Natalie Brahan, Lexi Xu, Leyuan Zhang, Kaitlyn Su, Kody Seow, Julia Vu, Charissa Luk, Yunseo Lee, Anirudh Raman, Joseph Pazzi, Edward Njoo

“…Abstract Initially developed as a derivatized analog of 5-fluorouracil for the treatment of colorectal cancer, carmofur has more recently demonstrated potent covalent inhibition of the main protease (Mpro) of SARS-CoV-2. …”
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Multimodal versus non-contrast computed tomography for assessment of acute ischaemic stroke: the PRACTISE RCT by Keith W Muir, Salwa El Tawil, Alex McConnachie, Alicia Murray, Ian Ford, Grant Mair, Joanna Wardlaw

“…The potential for improved patient selection and treatment targeting is balanced by concern that additional imaging might delay reperfusion treatment. …”
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Regional Design by Verena Balz

“…The chapter presents an initial review of a regional-design practice that was conducted between 2005 and 2007 by South Wing Studio (Atelier Zuidvleugel). …”
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Breeding of a new white-fleshed loquat cultivar Puhuabai by LIN Shoukai, TU Siping, MA Shiwei, LIN Zhicong, FAN Guofan, LIN Shunquan, WU Jincheng

“…., Xiazheng, Longqiao Yangxi, Xiuyu District, Dayang Keshan, and Yuanpu) revealed its stable traits, including large fruit size, excellent flavor, high yield, and good disease resistance, leading to its preliminary selection as an elite line. In 2020, Putian University initiated systematic breeding and temporarily named it Puhuabai. …”
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Milk ladder: Who? When? How? Where? with the lowest risk of reaction by Betul Buyuktiryaki, Ozge Soyer, Duygu Yazici, Duygu Yazici, Gulbin Bingol, Ceren Can, Hikmet Tekin Nacaroglu, Aysen Bingol, Ebru Arik Yilmaz, Metin Aydogan, Cansin Sackesen

“…Here, we reviewed current data on implementing the ML, suggested a 4-step ML including receipts and amounts, and shared our experience on optimal patient selection, appropriate time and steps for initiating ML, and time intervals between the steps targeting the lowest risk of reaction. …”
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Metabolic Reprogramming in Toll-like Receptor-Mediated Platelet Activation by Lih T. Cheah, Jawad S. Khalil, Mary McKay, Mohammad Ali, Cedric Duval, Amanda J. Unsworth, Khalid M. Naseem

“…Targeting platelet metabolism plasticity may offer a novel strategy to inhibit platelet function in TLR-initiated diseases.…”
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Optimizing mobile cognitive assessment reduces administration time while maintaining screening accuracy in older adults by Hyun Jeong Ko, Jin Sung Kim, Whani Kim, Byung Hun Yun, So Yoon Park, Dong Han Kim, Ui Jun Kwon, Sang Kwon Lim, Bo Ri Kim, Jee Hang Lee, Geon Ha Kim, Jin Woo Kim

“…The best-performing CatBoost model achieved an area under the curve (AUC) of 0.813, with sensitivity of 0.903, requiring an average completion time of 321 s. Subsequent feature selection identified two essential subtests for a compact DACI. …”
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Extreme UV sensitivity of native Metarhizium spp. as potential biocontrol agent for False Codling Moth (Thaumatotibia leucotreta Meyrick) on chili pepper in Ghana by Patricia Akua Sitsofe Nyahe, Vincent Yao Eziah, Laith Khalil Tawfeeq Al-Ani, Monica Akumyoungta, Candice Anne Coombes, Drauzio Eduardo Naretto Rangel, Alene Alder-Rangel, Dalia Sukmawati, Owusu Fordjour Aidoo, Mavis Agyeiwaa Acheampong

“…To facilitate the selection of these virulent isolates for development into a mycoinsecticide for FCM, the UV sensitivity and virulence following UV exposure were investigated for all seven isolates in this study. …”
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A Fish-Counting Method Using Fusion of Spatial Sensing and Temporal Information by Zhaozhi Wu, Xinze Zheng, Yi Zhu, Longhao Wu, Congcong Li, Qiang Tu, Fei Yuan

“…This paper introduces a fish-counting approach that integrates spatial sensing with temporal information. Initially, a spatial sensing matrix is constructed using ultrasonic Frequency-Modulated Continuous Wave (FMCW) technology, which facilitates the extraction of multidimensional features from fish echoes and reduces reliance on prior knowledge of fish schools. …”
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The impact of vitamin D deficiency on caries, periodontitis, and oral cancer: A systematic review by A.S. Hussein, R.A. Rosli, R.S. Ramle, G.H Khor

“…The PRISMA process was used for the screening and selection studies. Results: Initially, 3001 studies were identified. …”
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Human immunodeficiency virus-1 induces host genomic R-loops and preferentially integrates its genome near the R-loop regions by Kiwon Park, Dohoon Lee, Jiseok Jeong, Sungwon Lee, Sun Kim, Kwangseog Ahn

“…The invisible infection by HIV-1 integrating into non-genic regions, challenging the traditional understanding of HIV-1 integration site selection, is more problematic because they are selected for preservation in the host genome during prolonged antiretroviral therapies. …”
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Self-Perceived Comfort in Performing Basic Life Support Among Medical Students in Saudi Arabia: A Cross-Sectional Study by Maan Jamjoom, Bsaim Abdulsalam Altirkistani, Mohammed Ahmed Sayes, Hassan Alalawi, Abdulrahman Osama Alibrahim

“…Background: High quality and immediate initiation of cardiopulmonary resuscitation (CPR) can contribute to improve the survival rates and outcomes of cardiac arrests. …”
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Haptic Icons: A Hands-On Approach to Haptic HMI in Automated Vehicles by Joseba Sarabia, Myriam Vaca, Mauricio Marcano, Sergio Diaz, Joshue Perez Rastelli, Asier Zubizarreta

“…An iterative, three-phase methodology was employed: (1) The initial set of haptic notifications was designed based on input from the literature review, (2) These notifications were then tested in a driving simulator to identify the most effective options, and (3) The selected notifications were evaluated in a dynamic simulator under realistic conditions, including noise, vibration, and harshness (NVH). …”
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Dimensionality Reduction using Hybrid Algorithms and Their Application to Remote Sensing Data by Maha Hasso, Mona Siddiq

“…By applying it on the first group of images it concluded that the sixth band is the best one, because the value of its Eigen vector is the biggest one. when the algorithm was applied on the second group of images it concluded that the second band is the best one, and the value of its Eigen vector is the biggest one, when the algorithm was applied on the third group of images it concluded that the fifth band is the best, and the value of its Eigen vector is the biggest one (regarding separating the sixth infrared band in the three groups By using wavelet transform algorithm for one level of analysis and selecting the best band according to the least value of mean square error , to show the result of selecting the best ,the k_means algorithm  was used to classify images By using K_mean classification algorithm in images .A new way was proposed to determine  centers which is an important matter in accurate  classifications and specifying initial centers  by finding the maximum value and minimum value   and finding the mean between them until getting the wanted number of centers. …”
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Requirements for Becoming a Startup: A Study with an Economic Sociology Approach (Case Study: Managers of Startups in Isfahan City) by Rahmatollah Torkan, Seyed Samad Beheshty, Ramin Moradi

“…Iran is no exception to this movement with various initiatives aimed at developing its startup sector. …”
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Designing for Engagement in Primary Health Education Through Digital Game-Based Learning: Cross-National Behavioral Evidence from the iLearn4Health Platform by Evgenia Gkintoni, Emmanuella Magriplis, Fedra Vantaraki, Charitini-Maria Skoulidi, Panagiotis Anastassopoulos, Alexandra Cornea, Begoña Inchaurraga, Jaione Santurtun, Ainhoa de la Cruz Mancha, George Giorgakis, Kleri Kouppas, Stella Timotheou, Maria Jose Moreno Juan, Miren Muñagorri, Marta Harasiuk, Alfredo Garmendia Lopez, Efi Skoulidi, Apostolos Vantarakis

“…Multiple regression analysis identified initial design experience as the strongest predictor of continued engagement (β = 0.479, <i>p</i> < 0.001), followed by country-specific implementation factors (Romania vs. …”
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Predicting Endpoint Temperature of Molten Steel in VD Furnace Refining Process Using Metallurgical Mechanism and Bayesian Optimization XGBoost by Ji XU, Zicheng XIN, Mo LAN, Wenhui LIN, Bo ZHANG, Qing LIU

“…The dataset is randomly shuffled, with 80% selected as the training set and the remaining 20% as the testing set. …”
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Barriers to effective antimicrobial resistance management in Nigerian livestock: the role of veterinary practices and client expectations by Oluwafemi Babatunde Daodu, Esther Gbeja Olusegun, Godwin Adegbehingbe, Sola Emmanuel Komolafe, Oluwakemi Christiana Daodu

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Predicting Mortality in Low-Income Country ICUs: The Rwanda Mortality Probability Model (R-MPM). by Elisabeth D Riviello, Willy Kiviri, Robert A Fowler, Ariel Mueller, Victor Novack, Valerie M Banner-Goodspeed, Julia L Weinkauf, Daniel S Talmor, Theogene Twagirumugabe

“…Mechanical ventilation was initiated for 85.3%, and 41.9% received vasopressors. …”
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The The effects of the SPARK program on physical activity engagement in 11-year-old children by SITI AISHAH ABD RAHMAN, Nurul Diyana Sanuddin, Norlaila Azura Kosni, Nurshahira Ibrahim, Adjullea James @ Noew, Asmalini Che Abu Shafie, Theresa Ahing, Gordon Nicolaus Jemat Anchang, Mohamed Azizul Mohamed Afandi

“…This SPARK program contains four physical and four skill fitness activities that will be applied for eight (8) weeks in four selected primary schools in Perak. This study is a quasi-experimental pre and post-control group design. 240 children consisting of boys and girls were selected as a study sample. …”
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