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  1. 341

    Selective depletion of metastatic stem cells as therapy for human colorectal cancer by María Virtudes Céspedes, Ugutz Unzueta, Anna Aviñó, Alberto Gallardo, Patricia Álamo, Rita Sala, Alejandro Sánchez‐Chardi, Isolda Casanova, María Antònia Mangues, Antonio Lopez‐Pousa, Ramón Eritja, Antonio Villaverde, Esther Vázquez, Ramón Mangues

    Published 2018-09-01
    “…In contrast to free oligo‐FdU, intravenous T22‐GFP‐H6‐FdU selectively accumulates and internalizes in CXCR4+ cancer cells, triggering DNA damage and apoptosis, which leads to their selective elimination and to reduced tumor re‐initiation capacity. …”
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  2. 342
  3. 343

    The Impact of Disability Disclosure on Fairness and Bias in LLM-Driven Candidate Selection by Mahammed Kamruzzaman, Gene Louis Kim

    Published 2025-05-01
    “…This data is collected to support diversity and inclusion initiatives, but when provided to LLMs, especially disability-related information, it raises concerns about potential biases in candidate selection outcomes. …”
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  4. 344

    WDR75: An essential protein for ribosome assembly undergoing purifying selection. by Lauren Lee, Justen B Whittall

    Published 2025-01-01
    “…In our comparison of 70 mammalian WDR75 sequences, we found ~25% of sites with significant purifying selection and no evidence of positive selection. Purifying selection was ~5x stronger for sites folding into beta-sheets than those predicted to be coils. …”
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  5. 345

    Heme-mediated selection of encapsulated Streptococcus pneumoniae in the lungs by oxidative stress by Babek Alibayov, Ana G. Jop Vidal, Landon Murin, Anna Scasny, Kenichi Takeshita, Komal Beeton, Kristin S. Edwards, Tracy Punshon, Brian P. Jackson, Larry S. McDaniel, Jorge E. Vidal

    Published 2025-12-01
    “…However, the underlying mechanisms remain unclear and likely involve multiple bacterial and host factors.We investigated the selection process of encapsulated pneumococci, a critical factor in lung damage during pneumococcal pneumonia.Our study revealed that pneumococci initially lack capsules but re-encapsulate upon reaching the alveoli. …”
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  6. 346

    Identification of selective SWI/SNF dependencies in enzalutamide-resistant prostate cancer by Bengul Gokbayrak, Umut Berkay Altintas, Shreyas Lingadahalli, Tunc Morova, Chia-Chi Flora Huang, Betul Ersoy Fazlioglu, Ivan Pak Lok Yu, Batuhan M. Kalkan, Paloma Cejas, Sonia H. Y. Kung, Ladan Fazli, Akane Kawamura, Henry W. Long, Ceyda Acilan, Tamer T. Onder, Tugba Bagci-Onder, James T. Lynch, Nathan A. Lack

    Published 2025-02-01
    “…Abstract Enzalutamide is a potent second-generation antiandrogen commonly used to treat hormone-sensitive and castration-resistant prostate cancer (CRPC) patients. While initially effective, the disease almost always develops resistance. …”
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  7. 347
  8. 348

    A Highly Discriminative Hybrid Feature Selection Algorithm for Cancer Diagnosis by Tarneem Elemam, Mohamed Elshrkawey

    Published 2022-01-01
    “…The algorithm comprises a two-stage hybrid feature selection. In the first stage, an overall ranker is initiated to combine the results of three filter-based feature evaluation methods, namely, chi-squared, F-statistic, and mutual information (MI). …”
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  9. 349

    Choosing to succeed? Insights into doctoral students' supervisor selection and its outcomes. by Danila Pavliuk, Svetlana Zhuchkova

    Published 2025-01-01
    “…Research on doctoral supervision usually focuses on the attributes, styles, and roles of a supervisor during doctoral training, while the process and effects of initiating supervisor-supervisee relationships remain less explored. …”
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    Article
  10. 350

    Advancements in feature selection and extraction methods for text mining: a review by Lama Ayash, Abdulmohsen Algarni, Omar Alqahtani

    Published 2025-08-01
    “…The need to extract insights from text has initiated and overseen the progression of research in the text mining domain. …”
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    Article
  11. 351

    Mechanisms and therapeutic implications of selective autophagy in nonalcoholic fatty liver disease by Suwei Jin, Yujia Li, Tianji Xia, Yongguang Liu, Shanshan Zhang, Hongbo Hu, Qi Chang, Mingzhu Yan

    Published 2025-01-01
    “…Aim of review: This review aims to summarize the types, functions, and dynamics of selective autophagy that are of particular importance in the initiation and progression of NAFLD. …”
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  12. 352

    Cancer evolution is associated with pervasive positive selection on globally expressed genes. by Sheli L Ostrow, Ruth Barshir, James DeGregori, Esti Yeger-Lotem, Ruth Hershberg

    Published 2014-03-01
    “…In contrast, in the cancer evolutionary process the dominance of purifying selection is much reduced, allowing for a much easier detection of the signals of positive selection (adaptation). …”
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  13. 353

    Health promotion actions in mass-media for seniors in selected European countries by Maciej Bartłomiej Rogala

    Published 2022-03-01
    “… Background The paper consists results of research aimed at health promotion for older people (HP4OP) in mass-media in 10 selected European countries involved in project ProHealth 65+. …”
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  14. 354
  15. 355

    Selection of Trichoderma mutants with enhanced cellulase production and resistant to catabolite repression by Szakacs G, Megyeri L, Kovacs K, Zacchi G

    Published 2004-07-01
    “…Isolate F-1505 was subjected to NTG-mutation to select catabolite (glucose, glycerol) resistant mutants. …”
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  16. 356

    Assessing the effectiveness of social accountability interventions in selected district assemblies in Ghana by Patrick Osei-Kufuor, Emmanuel Yamoah Tenkorang, Frederick Koomson, Richard Oppong Ntiri

    Published 2024-12-01
    “…However, there has been a minimal systematic attempt to document the effectiveness of social accountability initiatives, especially their ability to stimulate accountability actions by citizens. …”
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  19. 359

    The bidirectional selection and shared adaptation mechanisms of tumor organ-specific metastasis by WANG Xing, XIAO Ruiling, BAI Jialu, JIANG Decheng, ZHOU Feihan, LUO Xiyuan, TANG Yuemeng, ZHAO Yupei

    Published 2025-05-01
    “…Thus, the bidirectional selection and adaptation between tumor cells and target organs form a dynamic, complex system that reshapes our understanding of metastatic tumor development. …”
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  20. 360

    The roadmap for creating a novel outdoor activity space in a rehabilitation hospital setting: the OASIS program initiative by Pazit Levinger, Jill Hall, Keith D Hill

    Published 2025-07-01
    “…Method This descriptive case study reports the step-by-step process from initial concept to activation of the space. Drawing on internal planning documents, site plans, meeting records, and project materials, it outlines key phases including stakeholder consultation, site selection, design development, equipment installation, staff training, risk management, and pilot testing of a group-based exercise program. …”
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