Rifampicin-resistant tuberculosis in Fujian Province, Southeast China: a retrospective analysis of drug resistance screening and treatment outcomes, 2019–2024 by Yinfa Zhou, Zhisong Dai, Zhisong Dai, Shufang Lin, Shufang Lin, Daiquan Chen, Jian Lin, Kun Chen, Yongming Lin, Yanqin Deng, Yanqin Deng

“…Of 1,056 RR-TB patients initiated on treatment, 720 had outcome data, revealing a low success rate (58.6%) due to high loss to follow-up (31.1%) and mortality (9.3%). …”
Get full text

The science at HIVR4P 2024: The era of choice in biomedical HIV prevention by Beatriz Grinsztejn, Victor Appay, Linda‐Gail Bekker, Chris Beyrer, Deborah Donnell, Jorge Sanchez, Davina Canagasabey, Carolina Coutinho, Yonatan Ganor, Vincent Muturi‐Kioi, Katrina F. Ortblad, Erin Cooney, Gastón Devisich, Paula Ellenberg, Yanina Ghiglione, Kevin K'Orimba, Phionah Kibalama Ssemambo, Natasha Tatiana Ludwig‐Barron, Dieter Kenneth Mielke, Ranajoy Mullick, Michelle Kathini Muthui, Pablo D. Radusky, Emmanuel Sendaula, Syed Raza Haider Tirmizi, Akemi V. Matsuno Sanchez, Julian Vega, Roger Pebody

Get full text

Impact of Big Data Analytics on Emergency Department Efficiency in Saudi Ministry of Health Hospitals: A Retrospective Data Analysis by Senitan M, Alzahrani BJ

“…By analyzing data from over 228,000 patient records across 10 hospitals, we assessed the impact of the Ada’a Health Program, a data-driven initiative designed to improve hospital performance. …”
Get full text

Seasonal Changes in Performance Metrics, Hormonal, Hematological, and Biochemical Markers Among Semi-Professional Soccer Players: Implications for Training and Recovery by Eleftherios Mylonis, Dimitrios I. Bourdas, Natalia Kompodieta, Athanasios Tegousis, Panteleimon Bakirtzoglou, Athanasios Souglis, Evangelos Bekris

“…<b>Objectives</b>: This study examined physiological, biochemical, and performance adaptations in 18 semi-professional male soccer players across three seasonal phases: pre-season initiation (PS), pre-competition (PC), and mid-season (MS). …”
Get full text

Exploring the synergistic effects of drought and heat stress on chickpea seed development: Insights into nutritional quality and seed yield by Rashmi Awasthi, Poonam Devi, Uday Chand Jha, Kamal Dev Sharma, Manish Roorkiwal, Sanjeev Kumar, Ashwani Pareek, Kadambot H.M. Siddique, PV Vara Prasad, Swarup K. Parida, Harsh Nayyar

“…Seed composition elements (starch, storage proteins, sugars, fat, crude fiber, and ash) exhibited significant reductions across all stress treatments, particularly for the combined stress. …”
Get full text

Effects of SGLT2 Inhibitors on Sleep Apnea Parameters and Cheyne–Stokes Respiration in Patients with Acute Decompensated Heart Failure: A Prospective Cohort Study by Petar Kalaydzhiev, Tsvetelina Velikova, Yanitsa Davidkova, Gergana Voynova, Angelina Borizanova, Natalia Spasova, Neli Georgieva, Radostina Ilieva, Elena Kinova, Assen Goudev

“…Cardiac assessments revealed reductions in NT-proBNP (−329.6 pg/mL; <i>p</i> < 0.001) and E/e′ ratio (−1.08; <i>p</i> < 0.001), with no significant change in LVEF or chamber dimensions. …”
Get full text

Innovative pH-responsive alginate-coated rosuvastatin-loaded chitosan nanoparticles: a targeted approach to inhibiting HMGB1-activated RAGE/TLR4-NFκB signaling in colonic inflammat... by Elsayed A. Elmorsy, Elsayed A. Elmorsy, Sameh Saber, Zubida M. Al-Majdoub, Rabab S. Hamad, Mustafa Ahmed Abdel-Reheim, Asmaa Ramadan, Norah Suliman Alsoqih, Mariam S. Alharbi, Hamad Alsaykhan, Alshaimaa A. Farrag, Hanan Eissa, Rasha Abdelhady, Rasha Abdelhady, Abousree T. Ellethy, Mostafa M. Khodeir, Mostafa M. Khodeir, Hossam A. Elsisi, Hossam A. Elsisi, Syed Suhail Ahmed, Ahmed Y. Kira

“…Treatment resulted in substantial reductions in key inflammatory markers, including HMGB1, RAGE, TLR4 expression, NFκB activity, pro-inflammatory cytokines (TNF-α and IL-6), and apoptosis marker caspase-3. …”
Get full text

Efficacy and safety of anlotinib in combination with ¹³¹I therapy in the treatment of distant metastatic differentiated thyroid cancer: a single-arm, phase II study by Yan Li, Jianjing Liu, Jianjing Liu, Qian Su, Xueyao Liu, Zhen Yang, Zhao Yang, Jie Fu, Yan Zhang, Lina Tong, Fang Yang, Dong Dai, Dong Dai

“…When confirmed iodine uptake in metastatic lesions, anlotinib would be given at 12 mg (QD, 2 weeks on/1 week off, Q3W) initially. One combination treatment cycle consisted of 12 weeks of anlotinib and 1 dose of iodine-131. …”
Get full text

Inhibition of FAM19A5 reverses synaptic loss and cognitive decline in mouse models of Alzheimer’s disease by Han-Byul Kim, Sangjin Yoo, Hoyun Kwak, Shi-Xun Ma, Ryunhee Kim, Minhyeok Lee, Nui Ha, Soonil Pyo, Soon-Gu Kwon, Eun-Ho Cho, Sang-Myeong Lee, Juwon Jang, Won Kyum Kim, Hae-Chul Park, Minkyung Baek, Yosub Park, Ji-Young Park, Jin-Woo Park, Sun Wook Hwang, Jong-Ik Hwang, Jae Young Seong

“…Results FAM19A5 binds to LRRC4B, a postsynaptic adhesion molecule, leading to reductions in spine density in mouse hippocampal neurons. …”
Get full text

Multicentre comparison of various microaxial pump devices as a bridge to durable assist device implantation by Marta L. Medina, Daniel Lewin, Hendrik Treede, Sebastian V. Rojas, Alexander Bernhardt, Michael Billion, Anna L. Meyer, Ivan Netuka, Janajade Kooij, Marina Pieri, Antonio Loforte, Mauro Rinaldi, Mariusz K. Szymanski, Adriaan O. Kraajieveld, Christian J.H. Moeller, Payam Akhyari, Khalil Jawad, Bastian Schmack, Gloria Färber, Assad Haneya, Daniel Zimpfer, Gaik Nersesian, Ilija Djordjevic, Diyar Saeed, Finn Gustafsson, Anna M. Scandroglio, Bart Meyns, Steffen Hofmann, Jan Belohlavek, Jan Gummert, Pia Lanmueller, Evgenij V. Potapov, Mehmet Oezkur

“…Patients in the 5+ group demonstrated greater reductions in both vasoactive inotropic scores (P = 0.006) and inotropic scores (P = 0.008). …”
Get full text

Isolation and identification of strawberry anthracnose and fungicide screening in Henan province by SUN Wenbin, ZHANG Jingjing, SONG Yanhong, ZHAO Xia, LI Gang, ZHOU Houcheng, LIU Lifeng

“…Specifically recorded measurements for root length (3.72 cm), fresh weight (0.452 g), and dry weight (0.082 g) reflected significant reductions of 40.7%, 43.7%, and 64.6% respectively when compared with healthy control groups. …”
Get full text