Restorative Effects of Synbiotics on Colonic Ultrastructure and Oxidative Stress in Dogs with Chronic Enteropathy by Dipak Kumar Sahoo, Tracey Stewart, Emily M. Lindgreen, Bhakti Patel, Ashish Patel, Jigneshkumar N. Trivedi, Valerie Parker, Adam J. Rudinsky, Jenessa A. Winston, Agnes Bourgois-Mochel, Jonathan P. Mochel, Karin Allenspach, Romy M. Heilmann, Albert E. Jergens

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Effectiveness of Switching from Multiple-Inhaler to Once-Daily Single-Inhaler Triple Therapy in Patients with COPD in a Real-World Setting in Japan by Requena G, Camidge LJ, Ford A, Yarita M, Hashimoto K, Jennison T, Massey OS, Noorduyn SG, Mizukami A

“…There was a significant reduction in severe exacerbations post-switch (RR: 0.68, 95% CI: 0.51– 0.90; p=0.0084). …”
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Evaluation of mobile health technology combining telemonitoring and teleintervention versus usual care in vulnerable-phase heart failure management (HERMeS): a multicentre, randomi... by Sergi Yun, MD, ProfPhD Josep Comín-Colet, MD, Esther Calero-Molina, RN, Encarnación Hidalgo, RN, Núria José-Bazán, RN, Marta Cobo Marcos, MD, Teresa Soria, RN, Pau Llàcer, PhD, Cristina Fernández, MSc, José Manuel García-Pinilla, PhD, Concepción Cruzado, RN, Álvaro González-Franco, MD, Eva María García-Marina, RN, José Luis Morales-Rull, PhD, Cristina Solé, MD, Elena García-Romero, MD, Julio Núñez, PhD, José Civera, RN, Coral Fernández, RN, Mercedes Faraudo, RN, Pedro Moliner, PhD, Francesc Formiga, PhD, Javier de-Juan Bagudá, MD, Isabel Zegri-Reiriz, PhD, José María Verdú-Rotellar, PhD, Emili Vela, PhD, David Monterde, MSc, Jordi Piera-Jiménez, PhD, Gerard Carot-Sans, PhD, Cristina Enjuanes, PhD, Santiago Jiménez-Marrero, Alberto Garay, Raúl Ramos-Polo, Alexandra Pons-Riverola, Herminio Morillas, Sílvia Jovells-Vaqué, Marta Tajes, Rafael de la Espriella, Elisa Esther Rodríguez, Jessica Paola Rugeles, Maria del Carmen Moreno, Carla Castillo, Ainhoa Robles-Mezcua, Ramon Bascompte, Paola Macarena Beltran Troncoso, Rocío Rodríguez, Román Freixa Pamias, Olga Guri, Cristina Delso Gafarot, Sònia Sarret Vila, Angelique-Casas Thomsen, Jordi Fernández

“…Methods: The Heart Failure Events Reduction with Remote Monitoring and eHealth Support (HERMeS) trial was a 24-week, randomised, controlled, open-label with masked endpoint adjudication, phase 3 trial conducted in ten centres (hospitals [n=9] and a primary care service [n=1]) experienced in heart failure management in Spain. …”
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A Comprehensive Analysis of Spitzer 4.5 μm Phase Curves of Hot Jupiters by Lisa Dang, Taylor J. Bell, Ying (Zoe) Shu, Nicolas B. Cowan, Jacob L. Bean, Drake Deming, Eliza M.-R. Kempton, Megan Weiner Mansfield, Emily Rauscher, Vivien Parmentier, Alexandra Rochon, Kevin B. Stevenson, Mark Swain, Laura Kreidberg, Tiffany Kataria, Jean-Michel Désert, Robert Zellem, Jonathan J. Fortney, Nikole K. Lewis, Michael Line, Caroline Morley, Adam Showman

“…We present a comprehensive reduction and analysis of Spitzer’s 4.5 μ m phase curves of 29 hot Jupiters on low-eccentricity orbits. …”
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Effectiveness of Molnupiravir and Nirmatrelvir-Ritonavir in CKD Patients With COVID-19 by Franco Wing Tak Cheng, Vincent Ka Chun Yan, Eric Yuk Fai Wan, Celine Sze Ling Chui, Francisco Tsz Tsun Lai, Carlos King Ho Wong, Xue Li, Irene Ran Zhang, Sydney Chi Wai Tang, Ian Chi Kei Wong, Esther Wai Yin Chan

“…There was a greater risk reduction in males and those with higher Charlson Comorbidity Index (CCI). …”
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Baseline characteristics of patients with acute ischaemic stroke included in the randomised controlled Find-AF 2 trial by Katrin Wasser, Tobias Uhe, Wolf-Rüdiger Schäbitz, Martin Köhrmann, Martin Dichgans, Johannes Brachmann, Ulrich Laufs, Götz Gelbrich, David Petroff, Christiane Prettin, Dominik Michalski, Johann Pelz, Andrea Kraft, Thorleif Etgen, Hassan Soda, Florian Bethke, Peter D. Schellinger, Katharina Althaus, Gerhard F. Hamann, Martin Grond, Bernd Kallmünzer, Martina Petersen, Lars-Peder Pallesen, Michael Ertl, Philipp Zickler, Sven Poli, Karl Georg Haeusler, Thorsten Steiner, Paul Sparenberg, Pawel Kermer, Anna Kopczak, Lars Kellert, Martin Nückel, Jan Liman, Peter Arthur Ringleb, Meinhard Mende, Marcus Wagner, Deborah Bochert, Marlena Schnieder, Imke Amanzada, Sonja Gröschel, Marianne Hahn, Timo Uphaus, Klaus Gröschel, Rolf Wachter, on behalf of the Find-AF 2 study group

“…Abstract Background In the Find-AF 2 randomised controlled trial, we investigate whether a risk-adapted intensified heart rhythm monitoring with subsequent initiation of oral anticoagulation in ischaemic stroke patients leads to a reduction of recurrent ischaemic stroke and systemic embolism. …”
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Intersecting factors of disadvantage and discrimination and their effect on daily life during the coronavirus pandemic: the CICADA-ME mixed-methods study by Carol Rivas, Amanda P Moore, Alison Thomson, Kusha Anand, Zainab Zuzer Lal, Alison Fang-Wei Wu, Ozan Aksoy

“…Existing patients given a revised date were initially less likely to feel in limbo, a novel finding. …”
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Investigating the Relationship between Financialization and Long-Term Use of Short-Term Debt by Seyed Reza Seyed Nezhad Fahim

“…Furthermore, financialization is associated with a reduction in investment in productive assets. The findings also indicate that financialization diminishes firms' willingness to obtain internal financing. …”
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Measurement report: Crustal materials play an increasing role in elevating particle pH – insights from 12-year records in a typical inland city of China by H. Zhang, H. Zhang, S. Wang, S. Wang, Z. Dong, Z. Dong, X. Li, X. Li, R. Zhang, R. Zhang

“…Emerging concerns regarding aerosol acidity trends have been highlighted amid China's sustained initiatives to mitigate emissions of both acidic and alkaline precursors, especially in North China, which is significantly affected by dust aerosol. 12-year observational data in Zhengzhou reveal that the annual average <span class="inline-formula">PM_2.5</span> concentration decreased from <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M2" display="inline" overflow="scroll" dspmath="mathml"><mrow><mn mathvariant="normal">162</mn><mo>±</mo><mn mathvariant="normal">81</mn><mspace linebreak="nobreak" width="0.125em"/><mrow class="unit"><mi mathvariant="normal">µ</mi><mi mathvariant="normal">g</mi><mspace linebreak="nobreak" width="0.125em"/><msup><mi mathvariant="normal">m</mi><mrow><mo>-</mo><mn mathvariant="normal">3</mn></mrow></msup></mrow></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="78pt" height="15pt" class="svg-formula" dspmath="mathimg" md5hash="1a4aa4fbe0af84bc430f08a7efccb361"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="acp-25-6943-2025-ie00001.svg" width="78pt" height="15pt" src="acp-25-6943-2025-ie00001.png"/></svg:svg></span></span> in 2011 to <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M3" display="inline" overflow="scroll" dspmath="mathml"><mrow><mn mathvariant="normal">60</mn><mo>±</mo><mn mathvariant="normal">41</mn><mspace linebreak="nobreak" width="0.125em"/><mrow class="unit"><mi mathvariant="normal">µ</mi><mi mathvariant="normal">g</mi><mspace width="0.125em" linebreak="nobreak"/><msup><mi mathvariant="normal">m</mi><mrow><mo>-</mo><mn mathvariant="normal">3</mn></mrow></msup></mrow></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="72pt" height="15pt" class="svg-formula" dspmath="mathimg" md5hash="35a55c93e066c64a97a6a33966b6bee8"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="acp-25-6943-2025-ie00002.svg" width="72pt" height="15pt" src="acp-25-6943-2025-ie00002.png"/></svg:svg></span></span> in 2022, with the largest reduction in sulfate (73 %). …”
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Development and Validation of a Critical Thinking Questionnaire: A Case Study of the Lived Experience of Students from the University of Isfahan and Isfahan University of Medical S... by Esmaeil Kashef, Maghsod Farasatkhah, Vahid Ghasemi, Mozhgan Mohammadi Naeni

“…This reduction was achieved by eliminating factors with lower loadings or insufficient explanatory power in accounting for data variance. …”
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Clinical and cost-effectiveness of lithium versus quetiapine augmentation for treatment-resistant depression in adults: LQD a pragmatic randomised controlled trial by Jess Kerr-Gaffney, Zohra Zenasni, Kimberley Goldsmith, Nahel Yaziji, Huajie Jin, Alessandro Colasanti, John Geddes, David Kessler, R Hamish McAllister-Williams, Allan H Young, Alvaro Barrera, Lindsey Marwood, Rachael W Taylor, Helena Tee, Anthony J Cleare

“…Of those randomised to quetiapine, 95 were prescribed and initiated the medication. Of those allocated to lithium, 86 were prescribed and 84 initiated the medication. …”
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The underground argon project: procurement and purification of argon for dark matter searches and beyond by P. Agnes, P. Agnes, H. O. Back, W. Bonivento, M. G. Boulay, N. Canci, M. Caravati, M. Caravati, S. Cebrian, V. Cocco, D. Diaz Mairena, D. Franco, F. Gabriele, D. Gahan, D. Gahan, C. Galbiati, C. Galbiati, C. Galbiati, P. Garcia Abia, A. Gendotti, T. Hessel, S. Horikawa, S. Horikawa, R. Lopez Manzano, L. Luzzi, M. Martinez, V. Pesudo, M. Razeti, A. L. Renshaw, L. Romero, A. Rubbia, R. Santorelli, M. Simeone, M. Simeone, R. Stefanizzi, R. Stefanizzi, A. Steri, A. Steri, S. Sulis, S. Sulis

“…Following the results of DarkSide-50, the GADMC initiated the UAr project for extraction from underground and cryogenic purification of 100 t of argon to be used as a target in the next-generation experiment DarkSide-20k. …”
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Microbial diversity and composition in the gut microbiome of patients during systemic inflammatory response syndrome: can we use gut bacteria as potential biomarkers to characteriz... by Rafaela Ramalho Guerra, Rafaela Ramalho Guerra, Rafaela Ramalho Guerra, Patricia da Silva Fernandes, Otávio von Ameln Lovison, Otávio von Ameln Lovison, Giovanna de Ross Forni, Giovanna de Ross Forni, Gabriel Silva de Oliveira, Luana Cristina Viana, Dariane Castro Pereira, William Latosinski Matos, William Latosinski Matos, Miriane Melo Silveira Moretti, Fabiana Zempulski Volpato, Luciana Giordani, Luciana Giordani, Patricia Orlandi Barth, Patricia Orlandi Barth, Tarsila Vieceli, Diego Rodrigues Falci, Márcio Manozzo Boniatti, Afonso Luís Barth, Afonso Luís Barth, Afonso Luís Barth, Andreza Francisco Martins, Andreza Francisco Martins, Andreza Francisco Martins, Andreza Francisco Martins

“…Turicibacter spp. showed a reduction in the prolonged AT sepsis group, while Klebsiella spp. was more abundant in the BL-combined sepsis patients.ConclusionsSepsis and non-sepsis patients showed distinct gut microbiota profiles in early AT. …”
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Seroprevalence of dengue in the Democratic Republic of Congo, Ghana and Senegal: results of the SERODEN study by Anthony Afum-adjei Awuah, Aboubacry Gaye, Antoine Nkuba-Ndaye, Anna Vicco, Moussa Dia, Oumar Ndiaye, Ndoumbe Ndiaye, Franck William Mendy, Mame Daba Thiam, Idrissa Dieng, Benoit Mputu-Ngoyi, Paul Tshiminyi Munkamba, Lionel Baketana-Kinzonzi, Elysé Matungulu-Biyala, Frida Nkawa, Evans Asamoah Adu, Eric Ebenezer Boham, Hakim Alani, Akua Pomaah Wiredu, Louis Adu-Amoah, Clare McCormack, Martine Guillerm, Christian Obirikorang, Shubham Shrivastava, Guillaume Thaurignac, Eva Lorenz, Nicole S. Struck, Jürgen May, Sheila Makiala-Mandanda, Isabela Ribeiro, Cheikh Loucoubar, Cheikh Talla, Christl A. Donnelly, Belen Pedrique, Steve Ahuka-Mundeke, John H. Amuasi, Oumar Faye, Ilaria Dorigatti

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Novel Pt@PCN-Cu-induced cuproptosis amplifies αPD-L1 immunotherapy in pancreatic ductal adenocarcinoma through mitochondrial HK2-mediated PD-L1 upregulation by Pengyu Wang, Weihua Guo, Shuyue Liu, Shouyi Li, Jiaqi Li, Bowen Ding, Fengyi Yin, Yang Yang, Xingjiang Li, Pei Cao, Chaozhe Ma, Wanying Zhang, Yidan Song, Yating Geng, Lantao Liu, Jing Hu, Jihui Hao, Yukuan Feng

“…Methods Pt@PCN-Cu was synthesized via a one-pot method, and its therapeutic potential was assessed in combination with αPD-L1 for the treatment of PDAC. Initially, the material’s properties were characterized, and its efficient cellular uptake was confirmed. …”
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Connecting climate science and society: reflections from early and mid-career researchers at the World Climate Research Programme Open Science Conference 2023 by Leandro B. Díaz, Leandro B. Díaz, Leandro B. Díaz, Carla Gulizia, Carla Gulizia, Carla Gulizia, Shipra Jain, Shipra Jain, Gaby S. Langendijk, Hindumathi Palanisamy, Valentina Rabanal, Valentina Rabanal, Candice S. Charlton, Alima Dajuma, Felix K. Donkor, Temitope S. Egbebiyi, Temitope S. Egbebiyi, Ghafi Kondi Akara, Ghafi Kondi Akara, Amna Jrrar, Md Rezwan Siddiqui, Yassine Ait Brahim, Yassine Ait Brahim, Bapentire D. Angnuureng, Anna-Adriana Anschütz, Founi M. Awo, Founi M. Awo, Alejandro Builes-Jaramillo, Alison Cobb, Mohamadou A. Diallo, Mohamadou A. Diallo, Houda Er-Retby, Houda Er-Retby, Houda Er-Retby, Thierry C. Fotso-Nguemo, Benjamin Gwinneth, Masilin Gudoshava, Franck E. Kemgang Ghomsi, Franck E. Kemgang Ghomsi, Franck E. Kemgang Ghomsi, Inés M. Leyba, Inés M. Leyba, Redouane Lguensat, Redouane Lguensat, Roché Mahon, Shailendra K. Mandal, Lucia Mumo, Meshel Muzuva, Meshel Muzuva, Rodric M. Nonki, Juan A. Rivera, Juan A. Rivera, Alcade C. Segnon, Alcade C. Segnon, Laouali I. Tanimoune, Erlich-Honest E. I. Zauisomue, Gilbert Siame

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Trajectory of plasma lipidome associated with the risk of late-onset Alzheimer's disease: a longitudinal cohort studyResearch in context by Tingting Wang, Matthias Arnold, Kevin Huynh, Patrick Weinisch, Corey Giles, Natalie A. Mellett, Thy Duong, Bharadwaj Marella, Kwangsik Nho, Alysha De Livera, Xianlin Han, Colette Blach, Chenglong Yu, John J. McNeil, Paul Lacaze, Andrew J. Saykin, Gabi Kastenmüller, Peter J. Meikle, Rima Kaddurah-Daouk

“…Methods: We employed longitudinal lipidomic profiling on 4730 plasma samples from 1517 participants of the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort to investigate the temporal evolution of lipidomes among diagnostic groups. …”
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The dynamics of the gut microbiota in prediabetes during a four-year follow-up among European patients—an IMI-DIRECT prospective study by Liwei Lyu, Yong Fan, Josef Korbinian Vogt, Marc Clos-Garcia, Amelie Bonnefond, Helle Krogh Pedersen, Avirup Dutta, Robert Koivula, Sapna Sharma, Kristine Højgaard Allin, Caroline Brorsson, Henna Cederberg, Elizaveta Chabanova, Federico De Masi, Emmanouil Dermitzakis, Petra J. Elders, Marieke T. Blom, Monika Hollander, Rebeca Eriksen, Ian Forgie, Gary Frost, Giuseppe N. Giordano, Harald Grallert, Mark Haid, Tue Haldor Hansen, Bernd Jablonka, Tarja Kokkola, Anubha Mahajan, Andrea Mari, Timothy J. McDonald, Petra B. Musholt, Imre Pavo, Cornelia Prehn, Martin Ridderstråle, Hartmut Ruetten, Leen M.‘t Hart, Jochen M. Schwenk, Evelina Stankevic, Henrik S. Thomsen, Jagadish Vangipurapu, Henrik Vestergaard, Ana Viñuela, Mark Walker, Torben Hansen, Allan Linneberg, Henrik Bjørn Nielsen, Søren Brunak, Mark I. McCarthy, Philippe Froguel, Jerzy Adamski, Paul W. Franks, Marku Laakso, Joline W. J. Beulens, Ewan Pearson, Oluf Pedersen

“…Trial registration The Diabetes Research on Patient Stratification (DIRECT) study, an exploratory observational study initiated on October 15, 2012, was registered on ClinicalTrials.gov under the number NCT03814915.…”
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Investigating the Location-Spatial Effects of Urban Tourism on the Stability of the Urban Spatial System (Case Study: Region 3 of Isfahan City) by Mina Kazemi, Aboozar Vafaei, Rasool Heydari Sureshjani

“…Materials & MethodsThis research employed a descriptive and analytical approach, focusing on practical objectives. Initially, a review of relevant texts, sources, and theoretical framework was conducted. …”
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日本解決學力下降問題之政策分析： 以課綱修訂和全國學力測驗為主 The Policy Analysis to Solve Academic Decline in Japan– Course of Study and National Assessment of Academic Ability... by 李宜麟 Yi-Lin Lee, 楊思偉 Szu-Wei Yang

“…To clarify the content of academic ability and address academic decline scientifically, Japan initiated the “National Academic Ability and Learning Status Survey” annually from 2007. …”
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