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Personalized dose reduction strategies for biologic disease-modifying antirheumatic drugs for treating axial spondyloarthritis: a clinical and economic evaluation with predictive m...
Published 2025-05-01“…Methods This 12-month prospective study, 368 AS patients receiving ≥ 3 months of full-dose bDMARDs were included. Among 215 initial responders (ASDAS < 2.1), 146 underwent dose reduction while 69 continued full-dose therapy. …”
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543
Comparison of clinical outcomes in acute versus staged open reduction-internal fixation of OTA/AO type 43C tibial pilon fractures
Published 2025-08-01“…Traditionally, delayed two-stage Open Reduction-Internal Fixation (sORIF) has been the standard treatment, involving initial external fixation followed by definitive fixation. …”
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Effects of External Water Pressure Reduction Coefficient on Parameters for High-Pressure Water injection test in Deep Boreholes of Pumped Storage Power Stations
Published 2025-01-01“…Generally, additional hydraulic pressure calculated with external water pressure reduction coefficient is greater than that specified in current standards, and shows a negative correlation with external water pressure reduction coefficient. …”
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546
Random forest algorithm integrated with an initial basic feasible solution in buckling analysis of a two-dimensional functionally graded porous taper beam
Published 2025-01-01“…Porosity is included by a porosity index, and the tapering effects are captured using linear thickness and width ratios. The Initial Basic Feasible Solution method is used to define boundary conditions and provide an initial physically consistent solution, which is further enhanced by the Random Forest model to handle complex nonlinear interactions. …”
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Effect of Initial Substrate pH and Light Intensity on Biohydrogen Production through photo-fermentation from Palm Oil Mill Effluent (POME)
Published 2024-07-01“…This research explores the influence of initial substrate pH and light intensity on the conversion of POME into biohydrogen through photo-fermentation. …”
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549
Striving for excellence in ventilator bundle compliance through continuous quality improvement initiative in the intensive care unit of a tertiary care hospital in India
Published 2024-11-01“…A P-value <0.05 was considered statistically significant. Results The initial observed compliance was 40.7%, with a significant difference between knowledge and implementation. …”
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550
Weight Percentile Is Maintained During Spica Casting: A Retrospective Cohort Study of Patients Treated with Closed or Open Reduction for Developmental Dysplasia of the Hip
Published 2024-11-01“…The primary aim of this study was to determine weight percentile change from cast initiation to cast removal. Secondary aims were to assess weight percentile changes from initiation to mid-term follow-up visits after cast removal and to assess the mean weight change from cast initiation to cast removal. …”
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551
Analysis of Factors Influencing Public Participation in Energy Conservation and Carbon Emission Reduction Projects in China’s Energy Industry Based on the Theory of Planned Behavio...
Published 2025-05-01“…As China’s carbon inclusion policies are gradually implemented, significant progress has been made in energy conservation and emission reduction. The economical use of energy is the basis for the reduction in carbon emissions, which is a direct reflection of the benefits of energy efficiency initiatives. …”
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552
Determinants of two-year mortality among HIV positive patients with Cryptococcal meningitis initiating standard antifungal treatment with or without adjunctive dexamethasone in Uga...
Published 2020-11-01“…Globally, early initiation of antiretroviral therapy for HIV led to a reduction in the estimated mortality from cryptococcal meningitis (CCM) from 624,700 in 2009 to 181,100 in 2014. …”
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Sustainable Governance on the Belt and Road Initiative Toward a Carbon-Zero, Regional, Eco-Friendly Logistics Hub: A Difference-In-Differences Perspective
Published 2024-11-01“…The Belt and Road Initiative (BRI) proposed by China in in 2013 prioritizes environmental sustainability and regional economic development from a global perspective. …”
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Trends in Salt Consumption and Reduction Practices in Vietnam During 2015–2021: Analyzing Urinary Sodium Levels Among 18–69 Aged Populations
Published 2025-03-01“…High-risk groups, including those with hypertension and diabetes, consumed more salt but also showed reductions. Awareness of salt reduction advice remained low, with only 60.9% of the general population informed.ConclusionWhile progress has been made in reducing salt intake, ongoing public health initiatives are essential to meet recommended levels, especially for high-risk populations.…”
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Gradual Variation-Based Dual-Stream Deep Learning for Spatial Feature Enhancement With Dimensionality Reduction in Early Alzheimer’s Disease Detection
Published 2025-01-01“…We evaluated the model on two datasets, Complete 1Yr 1.5T and Complete 3Yr 3T, from the Alzheimer’s Disease Neuroimaging Initiative (ADNI), using MRI scans from three planes (axial, sagittal, and coronal). …”
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Reduction in Average Ambulance Response Time of Interfacility Transfer for Life-saving Cases (STEMI, STROKE, RTA) in Eastern Health Cluster of Saudi Arabia
Published 2024-03-01“…Certain interventions were applied and there was a significant reduction in average response time for three life-saving categories from 17 minutes to 9 minutes. …”
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Vagus nerve stimulation: Novel concept for the treatment of glioblastoma and solid cancers by cytokine (interleukin-6) reduction, attenuating the SASP, enhancing tumor immunity
Published 2024-12-01“…The hypothesis predicts that electrical activation of the vagus nerve, with cytokine reduction, in combination with ICIs, would convert an immune resistant (“cold”) tumor to an immune responsive (“hot”) tumor, and halt glioma progression. …”
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Comparative Evaluation of Two Audio-analgesic Tracks on Reduction of Anxiety Level in Patients Undergoing Root Canal Treatment: A Randomised Clinical Study
Published 2025-06-01“…Aim: To compare the reduction in anxiety levels of patients undergoing endodontic therapy with two different audio-analgesic tracks. …”
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