Operationalizing the principles of patient engagement through a Patient Advisory Council: Lessons and recommendations by Ingrid Nielssen, Maria Santana, Surakshya Pokharel, Kimberly Strain, Veronika Kiryanova, Sandra Zelinsky, Zoha Khawaja, Prachi Khanna, Anni Rychtera, Anshula Ambasta

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Smart diabetes management: remote monitoring and predictive health insights by K.S. Smelyakov, I.A. Lurin, K.V. Misiura, A.S. Chupryna, T.V. Tyzhnenko, O.D. Dolhanenko, V.M. Repikhov

“…It holds promise for improving outcomes, reducing complications, and enhancing quality of life, especially when adapted to meet the needs of underserved populations.…”
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Peer-assisted telemedicine hepatitis-C treatment for people who use drugs in rural communities: a mixed methods study by Kim Hoffman, Gillian Leichtling, Sarah Shin, Andrew Seaman, Tonhi Gailey, Hunter C. Spencer, P. Todd Korthuis

“…Innovative treatment models are needed that circumvent healthcare system barriers for people who use drugs (PWUD), particularly in rural areas. …”
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ABCG2 protein expression in tumors of patients with non-resectable pancreatic cancer treated with gemcitabine and nab-paclitaxel by Susy Shim, Susy Shim, Mette Bak Nielsen, Mikkel Eld, Jan Stenvang, Jan Stenvang, Rasmus Froberg Brøndum, Rasmus Froberg Brøndum, Britta Weber, Anne Krejbjerg Motavaf, Morten Ladekarl, Morten Ladekarl

“…Given the unexpected direction of this association, our findings should be interpreted as hypothesis-generating, and further studies are needed to elucidate underlying biological mechanisms and validate ABCG2 as a potential predictive biomarker in this setting.…”
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Presupuesto de referencia para unas condiciones de vida dignas. Concepto, metodología y resultados en el caso español by Thomas Ubrich, Raúl Flores Martos, Francisco Javier de Lorenzo Gilsanz

“…The PRCVD serves as a framework that quantifies the necessary expenses to ensure dignified living conditions, considering the composition and specific needs of each household, thus providing a useful tool for analyzing and assessing the socio-economic conditions of households in Spain.…”
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Nanoformulations Downregulating METTL16 Combined with mRNA Tumor Vaccines Suppress Triple-Negative Breast Cancer and Prevent Metastasis by Wang R, Zhang Y, Du S, Li Y, Ren Y, Lin J

“…Traditional treatments such as surgical resection, radiotherapy, and chemotherapy are no longer sufficient to meet clinical needs. Based on prior research that identified METTL16 as a potential target for TNBC, this study aimed to develop a nanoformulation to mitigate the malignancy of TNBC by silencing METTL16. …”
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Establishing a new human pneumococcal standard reference serum, MPRSS-01 by Joseph M. Antonello, Rocio D. Murphy, Chitrananda Abeygunawardana, Juliana C. Malinverni, Rajam Gowrisankar, Tina Green, Rebecca Greway, Jenna Schmauch, Adrienne Howlett, Cyrille J. Bonhomme, Katrina M. Nolan

“…With the development of next-generation PCVs, a new S. pneumoniae reference serum standard was needed to include serotypes beyond the existing 24 in 007sp. …”
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Integral Scientific Advice for Outbreak Response: Lessons learned from an Avian Influenza Simulation in the Netherlands by Dr Anja Schreijer, Dr. Femke Overbosch, Dr. Tomris Cesuroglu, Dr Charlotte Waltz, Drs. Bart Blokland, Drs Jeanette de Boer, Drs Tim Florschutz

“…Conclusions: Interdisciplinary discussions are needed in pandemic advice to identify blind spots within the disciplinary recommendations. …”
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Hypertensive disorders of pregnancy and breastfeeding practices: A secondary analysis of data from the All Our Families Cohort by Kristin Horsley, Kathleen Chaput, Deborah Da Costa, Tuong‐Vi Nguyen, Natalie Dayan, Lianne Tomfohr‐Madsen, Suzanne Tough

“…Conclusions Hypertensive disorders of pregnancy are associated with altered breastfeeding practices and experiences during the first year postpartum. Further research is needed to examine biopsychosocial mechanisms through which hypertensive disorders associate with shorter breastfeeding duration, and to examine whether greater breastfeeding duration, intensity or exclusivity reduces short‐ or long‐term maternal cardiovascular risk.…”
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Two pediatric patients with secondary glioblastoma following radiotherapy for acute lymphoblastic leukemia: a case report by Nanae Chiba, Noriyoshi Takahashi, Hiroaki Ogawa, Takaya Yamamoto, Rei Umezawa, Masayuki Kanamori, Hidenori Endo, Keiichi Jingu

“…One patient (Case 1) survived without recurrence for more than 104 months after the initiation of radiation, whereas other patient died due to progression. …”
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A dual readout embryonic zebrafish xenograft model of rhabdomyosarcoma to assess clinically relevant multi-receptor tyrosine kinase inhibitors by Joseph W. Wragg, Emma L. Gray, Rui Monteiro, Jo R. Morris, Andrew D. Beggs, Ferenc Müller, Susanne A. Gatz, Susanne A. Gatz

“…Better therapeutic regimens and preclinical models to test them in are needed. Multi-receptor tyrosine kinase inhibitors (MRTKIs) are licensed for adult indications and explored in the clinic in sarcoma patients. …”
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In-vitro diagnostic point-of-care tests in paediatric ambulatory care: A systematic review and meta-analysis. by Oliver Van Hecke, Meriel Raymond, Joseph J Lee, Philip Turner, Clare R Goyder, Jan Y Verbakel, Ann Van den Bruel, Gail Hayward

“…Research is urgently needed to understand where POCTs are likely to improve clinical outcomes in paediatric settings worldwide.…”
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Exploring challenges in implementing antimicrobial stewardship interventions across eight African nations: A multi case study by Ms Maxencia Nabiryo, Miss Maxencia Nabiryo, Dr Helena Rosado, Miss Frances Garraghan, Miss Claire Brandish, Miss Victoria Rutter

“…In addition, realignment of project plans when and where needed, as well as efforts to secure additional funding and resources are underway to address the challenges identified. …”
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PrimerX: A Bayesian Multistage Cohort Embedded Randomised Trial to Evaluate the Role of Deferred Local Therapy of the Primary Tumour in Combination with Immune Checkpoint Inhibitor... by Orlane Figaroa, Patricia Zondervan, Rob Kessels, Johannes Berkhof, Maureen Aarts, Paul Hamberg, Maartje Los, Djura Piersma, Bart Rikhof, Britt Suelmann, Metin Tascilar, Astrid van der Veldt, Paul Verhagen, Hans Westgeest, Hilin Yildirim, Axel Bex, Adriaan Bins

“…With the advent of immune checkpoint inhibitor (ICI) combination therapy in first line, the role of CN needs to be reassessed. There is indirect evidence from small retrospective series that deferred CN after ICI combination therapy may lead to better outcomes. …”
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Fish and marine fatty acids intakes, the FADS genotypes and long-term weight gain: a prospective cohort study by Yoriko Heianza, Dianjianyi Sun, Lu Qi, Louis R Pasquale, Jian-Min Yuan, Tao Huang, Frank B Hu, Tiange Wang, Janey Wiggs, Hyon-Kyoo Choi, Jin Fang Chai, Xueling Sim, Chiea Chuen Khor, Yechiel Friedlander, Andrew T Chan, Gary Curhan, Immaculata De Vivo, Rob Martinu van Dam, Chew Kiat Heng, Charles Fuchs, Woon Puay Koh

“…Further investigation is needed to confirm our findings in other cohorts.…”
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Metabolic modulation to improve MSC expansion and therapeutic potential for articular cartilage repair by Ching Ann Tee, Daniel Ninio Roxby, Rashidah Othman, Vinitha Denslin, Kiesar Sideeq Bhat, Zheng Yang, Jongyoon Han, Lisa Tucker-Kellogg, Laurie A. Boyer

“…Process improvements that reduce cell heterogeneity while increasing donor cell numbers with improved chondrogenic potential during expansion culture are needed to realize the full potential of MSC therapy. …”
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Genome-Wide Methylation Sequencing to Identify DNA Methylation Markers for Early-stage Hepatocellular Carcinoma in Liver and Blood by Siyu Fu, Ruben G. Boers, Joachim B. Boers, Pam E. van der Meeren, Jean Helmijr, Vanja de Weerd, Michail Doukas, Maurice Jansen, Bettina E. Hansen, Roeland F. de Wilde, Dave Sprengers, Joost Gribnau, Saskia M. Wilting, José D. Debes, Andre Boonstra

“…Better non-invasive surveillance methods are needed to improve early detection and maximize survival. …”
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Knowledge towards health impacts of climate change among Amhara Sayint community, Northeastern Ethiopia by Genanew Mulugeta Kassaw, Asmamaw Malede, Adinew Gizeyatu, Metadel Adane, Asha Embrandiri, Awoke Keleb, Gete Berihun, Abebe Kassa Geto, Belachew Tekleyohannes Wogayehu, Gebremeskel Kibret Abebe, Tibebu Habtie Zewde, Sisay Abebe Debela, Solomon Seyoum, Amana Ogeto Luke, Gashaw Wondaya, Atitegeb Abera Kide, Mekonnen Moges, Denise Metoyer, Mesfin Gebrehiwot

“…Its findings are crucial for guiding future research and developing targeted public health strategies and educational initiatives.…”
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Does Levosimendan hasten veno-arterial ECMO weaning? A propensity score matching analysis by Nicolas Paulo, Antoine Kimmoun, David Hajage, Pierre Hubert, David Levy, Marc Pineton de Chambrun, Juliette Chommeloux, Ouriel Saura, Grégoire Del Marmol, Quentin Moyon, Guillaume Hékimian, Melchior Gautier, Charles Edouard Luyt, Guillaume Lebreton, Bruno Levy, Alain Combes, Matthieu Schmidt

“…Results from double-blinded randomized controlled trials are urgently needed to clarify the effectiveness and optimal timing of levosimendan in this specific population.…”
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Diurnal production of cortisol and prediction of treatment response in rheumatoid arthritis: a 6-month, real-life prospective cohort study by George E Fragoulis, Antonis Fanouriakis, Maria G Tektonidou, Petros P Sfikakis, Gerasimos Evangelatos, Vasiliki-Kalliopi Bournia, Katerina Laskari, Stylianos Panopoulos, GEORGE P CHROUSOS, Maria P Yavropoulou, Maria G Filippa, Nikolaos I Vlachogiannis, Aimilia Mantzou, Aggeliki Papapanagiotou

“…Objectives A reduced adrenal reserve-associated cortisol production relative to the enhanced needs of chronic inflammation (disproportion principle) has been observed in rheumatoid arthritis (RA). …”
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