Exploring the Impact of Different Approaches to Healthcare Support for Older Care Home Residents in Greater Manchester on Ambulance Services and Unplanned Hospital Admissions by Claire Hargreaves, Sue Tucker, Jane Hughes, Grace Hothersall, Megan Patterson, Vincent Gillan, David Challis

“… Context: Meeting the healthcare needs of care home residents is an international concern. …”
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Transcriptional regulatory network analysis identifies GRN as a key regulator bridging chemotherapy and immunotherapy response in small cell lung cancer by Seungyeul Yoo, Ayushi S. Patel, Sarah Karam, Yi Zhong, Li Wang, Feng Jiang, Ranran Kong, Sharon Bikvan, Wenhui Wang, Abhilasha Sinha, Charles A. Powell, Jun Zhu, Hideo Watanabe

“…Abstract Small cell lung cancer (SCLC) is an aggressive and heterogeneous subtype, representing 15% of lung cancer cases. Although SCLC initially responds to etoposide and platinum (EP) chemotherapy, nearly all patients relapse with resistant tumors. …”
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Robust development of data-driven models for methane and hydrogen mixture solubility in brine by Kashif Saleem, Abhinav Kumar, K. D. V. Prasad, Ahmad Alkhayyat, T. Ramachandran, Protyay Dey, Navdeep Kaur, R. Sivaranjani, I. B. Sapaev, Mehrdad Mottaghi

“…Abstract Within the domain of hydrogen storage initiatives inside subterranean structures, the accurate estimation of solubility of methane and hydrogen mixtures in brine becomes vital. …”
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Belatacept-based immunosuppression in heart transplant recipients: A single center experience by Wairimu Magua, PhD, MS, Maggie Wang, MD, MSc, Darlington Pobee, MD, Anna Morris, PhD, Alexis K. Okoh, MD, Emily M. Eichenberger, MD, MHS, Geeta M. Karadkhele, MS, Divya Gupta, MD, J. David Vega, MD, Christian P. Larsen, MD, PhD, Anne Van Beuningen, MD, Alanna A. Morris, MD MSc

“…Conclusion: Recipients treated with belatacept-based regimen exhibited a trend of reduced de novo DSA development compared to standard tacrolimus-based regimen controls. Larger studies are needed to evaluate the benefit of belatacept use in heart transplant populations.…”
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The effects of high-intensity training on walking speed and endurance in the subacute phase poststroke: a systematic review by Alejandro Ojeda-Manzano, Elsy Arlene Pérez-Padilla, Sergio Iván Sanguino-Suárez, Christine Cabelka, Humberto Salgado, Alexandra Borstad

“…Further randomized clinical trials are needed to strengthen the evidence.…”
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Effects of school-based interventions on all 24-hour movement behaviours in young people: a systematic review and meta-analysis of randomised controlled trials by José Francisco López-Gil, Javier Rodrigo-Sanjoaquín, Miguel Ángel Tapia-Serrano, Javier Sevil-Serrano

“…The study was registered in International Prospective Register of Systematic Reviews (PROSPERO) (ID: removed for peer review).Results Of the 5141 records initially identified, 41 studies remained for full-text review. …”
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Management of an Earthquake in a Pediatric Intensive Care Unit by Murat Tanyıldız, Ömer Özden, Lasin Özbek, Karya Şenköylü, Aysu Çakar, İlker Eren, Aslıcan Çakkalkurt, Mehmet Emin Menentoğlu, Ilmay Bilge

“…Fasciotomy was performed on 46.1% (n=6) of patients. Debridement was needed in 61.5% (n=8), averaging 3.6±3.8 procedures per patient. …”
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Selection of efficient broiler strain for productive performances and immunity under local farming system in Bangladesh by Mostafizor Rahman, Hemayet Hossain, Milon Mia, Md. Jamilur Rahman, Abu Al Farabi, Zhokhar Dudayev, Khadiza Akter Brishty, Nadia Afrin, Md. Arif Ishtiaq Shovon, Md. Shahidur Rahman Chowdhury, Md. Masudur Rahman, Md. Mahfujur Rahman

“…The poultry sector has emerged as an important contributor to the national economy of Bangladesh, meeting essential protein needs with quality products and progressing steadily toward a poultry-sufficient nation. …”
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Pulmonary lymphangiomatosis: insights into an ultra-rare disease by M. Polke, N. Polke, S. Piel, E. Brunnemer, J. Wälscher, K. Buschulte, A. Warth, C. P. Heussel, M. Eichinger, L. Frankenstein, M. Eichhorn, S. Miliauskas, F. J. F. Herth, M. Kreuter

“…However, further investigation is needed to understand the pathogenesis of lymphangiomatosis in order to establish therapeutic approaches.…”
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Genomic insights about the effect of sodium-glucose cotransporter 2 inhibitors: a systematic review by Pavitraa Saravana Kumar, Yogapriya Chidambaram, G. Shree Devi, Vettriselvi Venkatesan, Ramesh Sankaran, Nagendra Boopathy Senguttuvan, Thanikachalam Sadagopan, Dorairaj Prabhakaran

“…Sodium-glucose cotransporter 2 (SGLT2) inhibitors, initially developed for diabetes management, have demonstrated cardiovascular benefits, including reductions in HF hospitalizations and mortality. …”
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Co-designing solutions to tackle food insecurity in higher education settings: a scoping review by Taylah Scutts, Nadia Farnaz, Gantsetseg Ganbold, Alexandra J Bhatti, Shirley Phan, Miriam J Williams, Seema Mihrshahi

“…Conclusions: Co-designed research methodologies are important for addressing student FI, enhancing advocacy and understanding stakeholder needs. Future studies should prioritise collaborative approaches when exploring solutions to FI and similar social justice issues affecting students. …”
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Effectiveness of school-based active breaks on classroom behavior, executive functions and physical fitness in children and adolescent: a systematic review by Tomás Reyes-Amigo, Gabriel Salinas-Gallardo, Edgardo Mendoza, Camilo Ovalle-Fernández, Jessica Ibarra-Mora, Nicolás Gómez-Álvarez, Hernaldo Carrasco-Beltrán, Jacqueline Páez-Herrera, Juan Hurtado-Almonácid, Rodrigo Yañez-Sepúlveda, Rafael Zapata-Lamana, Rafael Zapata-Lamana, Felipe Sepúlveda-Figueroa, Jorge Olivares-Arancibia, Jorge Mota

“…Interventions involving active breaks and outcomes related to classroom behavior, executive functions, and physical fitness were considered.ResultsInitially, 145 studies were identified, with 22 duplicates excluded. …”
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A collaborative learning approach to improving health worker performance in adolescent sexual and reproductive health service provision: a descriptive feasibility study in six heal... by Sylvie Olela Odimba, Frances Squires, Erin Ferenchick, Symplice Mbola Mbassi, Paul Chick, Marina Plesons, Venkatraman Chandra-Mouli

“…We also carried out a quantitative analysis of the number, location, participants and topics of collaborative learning sessions conducted as part of this initiative, and thematic analysis to synthesise findings on perceived benefits and challenges. …”
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Adoption of E2PLUS tools and resources to promote the development of institutional capacity for patient-centered and community-engaged research at a cancer center by Katherine J. Briant, Prajakta Adsul, Elizabeth A. Carosso, Marty Chakoian, Diane Mapes, Terri Coutee, Bridgette Hempstead, Laurie Hassell, Wendy Law, Jason A. Mendoza

“…Results: Through E2PLUS engagement, the Champion Team identified four strategies to address institutional health inequities: 1) increase participation of underrepresented groups at all levels of institutional leadership and advisory boards; 2) create an Office of Patient Engagement to train and support patients who participate in institutional initiatives and advise research teams; 3) expand community engagement training, resources, and institutional commitment to focus on community-identified social and health needs; and 4) establish an umbrella entity for health equity efforts across the Consortium. …”
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Comparative evaluation of porcine and bovine bone xenografts in bone grafting: a systematic review and meta-analysis by Kun Wang, Jiatong Zhang, Mengyao Ding, Yifan Xie, Yan Wang, Chuyi Jin, Mengqing Yan, Lipei Liu, Cheng Ding, Xing Chen

“…Further well-designed randomized controlled trials are needed to evaluate long-term outcomes such as implant survival, graft resorption, and bone stability. …”
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Cost-effectiveness of an insertable cardiac monitor in a high-risk population in the UK by Mitchell S V Elkind, Claudia I Rinciog, Laura M Sawyer, Alexander Diamantopoulos, Matthew Reynolds, Stylianos I Tsintzos, Paul D Ziegler, Maria E Quiroz, Claudia Wolff, Klaus K Witte

“…ICMs were cost-effective in 77.4% of PSA simulations. The number of ICMs needed to prevent one stroke was 21 and to cause a major bleed was 37. …”
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Pertussis clinical profile shift, severity, prediction in a tertiary hospital: A comparative study before, during, and after COVID-19 in Southern China by Shufeng Tian, Yulan Chen, Qiru Su, Biao Sun, Zengrui Lin, Yuchun Long, Hongmei Wang, Cuijuan Liao, Ying Zhang, Jinjun Zheng, Lvjun Chen, Song Guan, Sen Wang, Xinlei Xu, Jingwen Ai, Wenhong Zhang, Jikui Deng

“…Conclusions: Post-pandemic, pertussis cases shifted from infants to school-aged children, with increased clinical severity and high macrolide resistance. Urgent measures are needed to optimize vaccination schedules and develop management strategies addressing and changing epidemiological patterns.…”
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Dual-faced guardians: SGLT2 inhibitors’ kidney protection and health challenges: a position statement by Kasralainy nephrology group (KANG) by Amin Roshdy Soliman, Mohamed Elkhatib, Sahier El-Khashab, Rasha Ahmed Darwish, Ahmed Fayed, Tarek S. Abdelaziz, Hany Hammad, Rabab Mahmoud Ahmed, Hoda Abdelhamid Maamoun

“…Kidney transplant recipients benefit from SGLT2 inhibitors’ protective effects on kidney health and assistance with diabetes management; however, further research is needed on drug compatibility with immunosuppressants and infection prevention.…”
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Creation of new anastomosis for management of obstructive symptoms related to gastrojejunal anastomosis in patients who undergo gastric bypass: a case series by Rohit Agrawal, MD, Ethan M. Cohen, MD, Ayowumi A. Adekolu, MD, Soban Maan, MD, Mouaz Haffar, MD, Monica Chowdhry, MD, Shyam Thakkar, MD, Shailendra Singh, MD

“…Large prospective studies with longer follow-up are needed to assess long-term outcomes of this intervention.…”
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Relationship between TyG-related index and hearing loss in people over 45 s in China by Chao Wang, Mengdi Shi, Liangzhen Xie, Chenhao Jiang, Yunxin Li, Jingxiao Li, Shulin Li, Yan Li

“…These findings highlight the importance of considering aging-related factors in public health initiatives aimed at preventing hearing loss. Further research is needed to elucidate the mechanisms underlying these associations and to develop age-inclusive strategies for addressing hearing impairment in the aging population.…”
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