Temporal Changes in Blood Metabolome Among Patients on Hemodialysis by Vida Dehghan Niestanak, Natasha Wiebe, Lun Zhang, David S. Wishart, Marcello Tonelli, Larry D. Unsworth

“…Future work on correlating toxins and clinical outcomes is needed to drive the development of technologies that improve blood purification for people with kidney failure.…”
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"Muro baixo, o povo pula": iniciativas institucionais de participação digital e seus desafios fundamentais by Francisco Paulo Jamil Almeida Marques

“…After presenting the participatory tools found on two institutional websites (the Brazilian Presidency and the House of Representatives), I examine how the constraints pointed out by a relevant part of the literature in e-participation are reflected on such initiatives. The discussion grounded on empirical evidences highlights the argument that promoting online participation needs more than providing communication resources, since civic culture and other issues are still key factors in influencing our patterns of political involvement. …”
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“I think people have been in survival mode”: a qualitative study of community connectivity in a neighbourhood of North East England before and during COVID-19 by Mandy Cheetham, Alice Wiseman, Stephen Ward, Sarah Gorman, Fiona Pollard

“…Further comparative implementation research is needed to examine the partnerships, values and principles that drive success and inclusion.…”
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Effect of remineralization after in office followed by home treatment of white spot lesions in children randomized controlled trial by Maryam M. El Mansy, Mohamed F. Rashed, Reham S. Saleh

“…Combined in office followed by continuous home application of different remineralizing agents could mask the WSLs which satisfy the patients’ needs. Trial registration: This study was initially registered on https://ClinicalTrials.gov on 12/02/2025 as first posted date, with ID: NCT06821724 - https://clinicaltrials.gov/study/NCT06821724 .…”
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Optimizing the interaction of service robots in elderly care institutions using multi-modal emotion recognition system based on transfer learning by Yongguan Ai, Yuanjun Zhang, Juan Wang, Nianfang Xu

“…Abstract As the global population continues to age, the emotional and mental health needs of older adults are becoming increasingly significant. …”
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Shinyscreen: mass spectrometry data inspection and quality checking utility by Todor Kondić, Anjana Elapavalore, Jessy Krier, Adelene Lai, Hiba Mohammed Taha, Mira Narayanan, Emma L. Schymanski

“…Its versatile list-based approach supports the curation of data starting from either known or “suspected” compounds (compound list-based screening) or detected masses (mass list-based screening), making it adaptable to diverse analytical needs (target, suspect or non-target screening). …”
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Insights into retention and safety/tolerability of apomorphine sublingual film in patients with Parkinson’s disease and OFF episodes: post hoc analyses of a phase III, open-label s... by Jan Kassubek, Diego Santos Garcia, Wolfgang H. Jost, Lars Wojtecki, Fradique Moreira, Miguel M. Fonseca, Glynn Harrison-Jones, Isabel Pijuan, Carmen Denecke Muhr

“…Background: Managing OFF episodes in patients with Parkinson’s disease becomes increasingly challenging over time, making it critical to tailor treatment to each patient’s needs and characteristics for effective care. Objectives: Study CTH-301 assessed the long-term safety/tolerability and efficacy of sublingual apomorphine (SL-APO) for the on-demand treatment of OFF episodes. …”
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Rethinking Human Security Through Feminist Lenses by Şirin Duygulu, Pınar Sayan

“…Problematizing the state's central role as the principal object of security allowed human beings' security needs and concerns to be put in front and center, at least in theory, if not necessarily in practice. …”
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Genotyping Genebank Collections: Strategic Approaches and Considerations for Optimal Collection Management by Noelle L. Anglin, Peter Wenzl, Vania Azevedo, Charlotte Lusty, David Ellis, Dongying Gao

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Nationwide experience of treatment with protease inhibitors in chronic hepatitis C patients in Denmark: identification of viral resistance mutations. by Christina Sølund, Henrik Krarup, Santseharay Ramirez, Peter Thielsen, Birgit T Røge, Suzanne Lunding, Toke S Barfod, Lone G Madsen, Britta Tarp, Peer B Christensen, Jan Gerstoft, Alex L Laursen, Jens Bukh, Nina Weis, DANHEP group

“…<h4>Methods</h4>80 patients, who initiated and completed triple therapy in Denmark between May 2011 and November 2012, were included. …”
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Intelligent Control of Smooth Blasting Quality in Rock Tunnels Using BP-ANN, ENN, and ANFIS by Baoping Zou, Jianxiu Wang, Zhanyou Luo, Lisheng Hu

“…The following are the conclusions of this study: (1) This paper presented a method of constructing a tunnel smooth blasting quality control index system and established this system with seven criteria layers, namely, geological conditions, explosive properties, borehole parameters, charge parameters, method of initiation, tunnel parameters, and construction factors, as well as a total of nine indexes. (2) The comprehensive optimization control model of BP-ANN, ANFIS, and ENN for tunnel smooth blasting quality was established. (3) The uniform design method was used to optimize the blasting parameters of the tunnel section, which needs to be controlled, and verify that the construction of these comprehensive optimization control models can change the focus of tunnel smooth blasting quality control from the traditional single index control method into a dynamic, intelligent, pluralistic, and integrated control technology.…”
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PO65 | Utilization of emicizumab in acquired hemophilia A: a case report

“…No further substitution of coagulation factors was needed. Conclusions: These findings underscore the therapeutic value of Emicizumab in patients with AHA and complex clinical profiles, demonstrating the efficacy in the reduction in bleeding risk throughout the course of treatment.   …”
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Who is the drug user activist?: recounting the conceptualisation of drug user activism in the United Kingdom by Raymond John S. Naguit, Shayla S. Schlossenberg, Praveena K. Fernes

“…Further forms of documentation are needed to develop a more holistic historical account of drug user activism in the UK.…”
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Factors that influence the feasibility and implementation of a complex intervention to improve the treatment of peripheral arterial disease in primary and secondary care: a qualita... by Athanasios Saratzis, Vanessa Lawrence, Ruth Benson, Emma Watson, Prakash Saha, Clair Le Boutillier, Bernadeta Bridgwood

“…The impetus for prioritising and delivering the intervention was further driven by its flexibility and adaptability to be tailored to the individual and to the environment.Conclusions The LEGS intervention can be tailored for use at early and late stages of peripheral arterial disease, provides an opportunity to meet patient needs and can be used to promote shared working across the primary–secondary care interface.…”
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Biomaterial-based drug delivery: evaluating the safety profiles of liposomal Vyxeos by Zhicheng Liu, Zhuo Fu, Yahui Liu, Yan Jiao

“…Most adverse events occurred within 30 days of treatment initiation, and 16.92% of reports involved hospitalization, while 18.33% reported death. …”
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Barriers and Facilitators to the Uptake and Maintenance of Healthy Behaviours by People at Mid-Life: A Rapid Systematic Review. by Sarah Kelly, Steven Martin, Isla Kuhn, Andy Cowan, Carol Brayne, Louise Lafortune

“…To engage people in health promotion initiatives in mid-life, a good understanding is needed of why people do not undertake healthy behaviours or engage in unhealthy ones.…”
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Sclerostin and Cardiovascular Risk: Evaluating the Cardiovascular Safety of Romosozumab in Osteoporosis Treatment by Shi-Hsun Chiu, Wen-Tien Wu, Ting-Kuo Yao, Cheng-Huan Peng, Kuang-Ting Yeh

“…Long-term studies are needed to evaluate chronic safety. Future therapeutic strategies should aim to maintain bone health while minimizing cardiovascular risks, ensuring a balance between efficacy and safety in osteoporosis treatment.…”
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Where there is no toilet: water and sanitation environments of domestic and facility births in Tanzania. by Lenka Benova, Oliver Cumming, Bruce A Gordon, Moke Magoma, Oona M R Campbell

“…However, a better conceptual understanding of potentially harmful exposures and better data are needed in order to devise and apply more empirical definitions of WATSAN-safe environments, both at home and in facilities.…”
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Prevalence of Pediculus humanus capitis and associated risk factors among elementary school-aged girls in Paveh, West Iran by Gona Bekri, Abdolreza Shaghaghi

“…Conclusions: Synchronized efforts to enhance public knowledge, periodic examination of school-aged children for pediculosis, and proper treatment of infested patients are needed to control the disease in the Iranian elementary schools. …”
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Analysis From Seven Years of DDA-Centered Collections Strategy Indicates Long-Term Effectiveness for Acquiring Electronic Monographs by Abbey Lewis

“…Supplementary strategies may be necessary for developing areas of the collection where needs are not met by the DDA plan, such as purchasing ebook packages and utilizing approval plans. …”
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